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Step 2 - Pharmacy 2014
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2 із 200
A pharmaceutist has to prepare an oil emulsion with menthol. Specify the appropriate way of the active substance incorporation:
Dissolution in oil
Dissolution in water intended for diluting the primary emulsion
Dispersion with the addition of ready emulsion
Incorporation into the ready primary emulsion
Dissolution in the ready emulsion by heating
3 із 200
It is required to prepare a decoction of bearberry leaves. Specify the ratio of raw materials to the extractant if not indicated in the formulation:
1:10
1:5
1:30
1:20
1:400
4 із 200
A pharmaceutist prepared an injectable solution of novocaine. What stabilizer had been used?
Hydrochloric acid solution
Sodium thiosulfate solution
Sodium sulfite solution
Stabilizator of Weibel
Sodium bicarbonate solution
5 із 200
A disabled veteran of the WW2 has been prescribed codeine powder. What is the maximum permissible amount of codeine that can be dispensed by the prescription?
0,2
1, 2
0, 1
1, 0
0, 6
6 із 200
Certain groups of drugs are subject to strict record keeping and storage in pharmacies. Specify a drug that relates to the group of narcotics:
Ethylmorphine hydrochloride
Dicaine
Clonidine
Dephedrinum
Analgene
7 із 200
Under the analytical normative documents, atropine sulfate should be titrated with hydrochloric acid solution in the anhydrous acetic acid medium in the presence of the following indicator:
Crystal violet
Thymol blue
Phenolphtalein
Methylene blue
Methyl orange
8 із 200
Losartan as a part of treatment of arterial hypertension is contraindicated in case of:
Pregnancy
Hypokalemia
Hyperlipidemia
Urine acid diathesis
Hyperglycemia
9 із 200
Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?
Streptokinase
Phenylinum
Ticlopidine
Heparin
Acetylsalicylic acid
10 із 200
At the end of the dug action drug addicts develop severe mental, neurological and somatic disorders. This complex of symptoms is called:
Withdrawal syndrome
Cumulation
Tolerance
Sensibilization
Tachyphylaxis
11 із 200
Patients with heart failure caused by persisting cardiac and coronary vessel dysfunction can be recommended preparations produced from the following herbal raw material:
Hawthorn fruits
Ginseng roots
Calendula flowers
Aralia roots
Barberry roots
12 із 200
Rutin exhibits P-vitamin activity. What medicinal plant is used as starting materials for the industrial production of rutin?
Fructus Sophorae japonicae
Flores Helichrysi arenarii
Herba Bidentis tripartitae
Herba Polygoni avicularis
Fructus Hippophaes rhamnoides
13 із 200
A patient came to a pharmacy to purchase cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?
Folium Uvae ursi
Herba Achilleae millefolii
Rizoma et radix Sanquisorbae officinalis
Radix Taraxaci officinalis
Rizoma Calami
14 із 200
Pharmaceutical warehouse received a batch of herbal raw material of cinnamon rose. Under the State Pharmacopoeia, it is required to test this raw material for the following active substances:
Ascorbic acid
Essential oil
Flavonoids
Tannins
Anthracene derivatives
15 із 200
Under the analytical normative documents, prior to direct bromatometric determination of arsenous acid anhydride the following substance should be added to the analyzed solution:
Potassium bromide
Sodium chloride
Potassium nitrate
Sodium hydroxide
Sodium thiosulfate
16 із 200
A pharmaceutical analyst of an analytical laboratory performs quantitative determination of silver nitrate by thiocyanatometry. What indicator is used in this case?
Iron (III) ammonium sulphate
Phenolphtalein
Sodium eosinate
Starch
Potassium chromate
17 із 200
A pharmaceutical company produces concentrated extracts. Specify the concentration of ethanol in the extractant required for the production:
20-40%
90-96 %
50-60 %
70-75 %
70-90 %
18 із 200
A factory workshop producing suspensions and emulsions is going to start manufacturing new drugs. What equipment can be used for the ultrasound processing of drugs?
Liquid whistle, magnetostrictive source
Dismembrator, electrical impulse plasmolyzer
Rotor-pulsation apparatus, di-smembrator
Disintegrator, liquid whistle
Centrifugal mixer with rotating housing
19 із 200
The ointment workshop of a pharmaceutical plant launches production of a new ointment. Specify the manufacturing operation that ensures equal distribution of the drug substance in the base:
Homogenization
Packaging
Standardization
Preparation of the base
Pre-packing
20 із 200
The aerosol workshop of a pharmaceutical plant uses various groups of propellants in the production. What propellants relate to the group of volatile organic solvents?
Methylene chloride, ethylene chloride
Propane, butane, isobutane
Freon (CFCs)
Vinyl and methyl chloride
Carbon dioxide
21 із 200
The phytochemical workshop of a pharmaceutical plant manufactures liquid extracts. How many volume parts of the liquid extract can be produced from one weight part of herbal raw material in compliamce with the State Pharmacopoeia?
1 part
10 parts
0,5 part
3 parts
5 parts
22 із 200
An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?
Chelatometry
Bromatometry
Nitritometric determination
Iodometry
Mercurimetric determination
23 із 200
A chemist of the production unit for ampouled medicinal preparations analyzes injectable solution of calcium chloride. According to the requirements, the analyzed solution should be colorless. To meet this requirement, the analyte should be compared to:
Water
Alcohol
Acetone
Hydrochloric acid
Chloroform
24 із 200
What drug is used as the specific antidote in case of intoxication with iron preparations?
Deferoxamine
Bemegride
Atropine
Penicillamine
Protamine sulfate
25 із 200
Specify the type of capsules which are used for dispensing camphor powders:
Parchment
Cellophane
Paraffin
Waxed
Common paper
26 із 200
A pharmacy received a formulation for an extemporaneously compounded medication. Specify the document that is used to set the price for such medication:
Retail price list for drugs
Inventory report
Certificate of analysis
Cash receipt voucher
Certificate of quality
27 із 200
A pharmaceutist has prepared a suspension ointment. Specify the substance used for this type of ointments:
Zinc oxide
Menthol
Protargolum
Ichthyol
Potassium iodide
28 із 200
Ergot (Secale cornutum) is used as an uterotonic agent in obstetric practice and for the treatmet of cardiovascular diseases. The authenticity of the raw materials is proved by the content of:
Ergotoxine
Ajmaline
Hyoscyamine
Atropine
Reserpine
29 із 200
Among the given principles of market segmentation select a principle that is used in the study of drug market most often:
Demographic
Behavioral
Psychological
Psychographic
Socio-economic
30 із 200
Personnel records refer to the following type of documents:
Managerial
Scientific
Pharmaceutical
Reference information
Directive
31 із 200
A pharmacy received a formulation for eye drops containing 1% solution of pilocarpine hydrochloride. What substance should be used to ensure that the resultant solution is isotonic?
Sodium chloride
Boric acid
Sodium sulfate
Sodium nitrate
Glucose
32 із 200
A pharmaceutist prepared 10 powders containing atropine sulfate in an amount of 0,00005 per dose. What trituration had been used?
1:100
1:50
1:1000
1:20
1:10
33 із 200
Which of the following antihypertensive drugs has potassiumsparing effect?
Triamterene
Diltiazem
Metoprolol
Prazosin
Furosemide
34 із 200
Immunochemical test for detection of opiates in urine is carried out on polystyrene plates with the use of horseradish peroxidase as a label. This method is classified as:
Heterogeneous immunoassay
Homogeneous immunoassay
Homogeneous immunofluorescence
Heterogeneous immunofluorescence
Heterogeneous radioimmunoassay
35 із 200
When developing the system of marketing communications, a company should consider the characteristics of each tool used for market promotion of a drug. Which of the following characteristics is typical for advertising?
Depersonalization (non-personal communication)
All answers are correct
Non-mass communication
There is no correct answer
Two-way communication
36 із 200
Quantitative determination of pyridine derivatives is performed by acidimetry in nonaqueous medium. What titrant is used for this purpose?
Perchlorate acid
Nitric acid
Sodium hydroxide
Sodium thiosulfate
Sulfuric acid
37 із 200
What antiprotozoal agent can be recommended to a female patient with trichomoniasis?
Metronidazole
Primaquine
Solusurminum
Chiniofonum
Chloridinum
38 із 200
A patient has a history of chronic bronchitis. Recommend him an expectorant which can be purchased at a pharmacy to facilitate the expectoration of thick and viscous mucus:
Ambroxol
Salbutamol
Glauvent
Libexin
Falimint
39 із 200
What drug from the group of cardiac glycosides can be used as an alternative for strophanthine if it is not available at a pharmacy?
Corglycon
Isolanidum
Celanidum
Adonisidum
Digitoxin
40 із 200
A pharmacy received the following formulation: Rp.: Xeroformii Picis Liquidae Betulae Olei Ricini 100,0 M.D.S. For wound anointing. Specify the dosage form:
Liniment
Paste
Solution
Combined ointment
Hydrophilic ointment
41 із 200
What is the most common symptom of atropine intoxication?
Mydriatic pupils with no light response
Reduction of intraocular pressure
Hyperhidrosis
Bradycardia
Myotic pupils with no light response
42 із 200
In order to detect the presence of thiosulfate ions a pharmaceutical analyst added the excess reagent. The resulting reaction produced a white precipitate which was slowly turning yellow, then brown, and black. What solution was added?
Silver nitrate
Barium chloride
Diphenylamine
Lead (II) acetate
Ammonium oxalate
43 із 200
Quantitative analysis of boric acid can be performed by alkalimetric titration in the presence of:
Mannitol
Mercury (II) acetate
Ethyl alcohol
Ammonia buffer
Nitric acid
44 із 200
A customer came to a pharmacy and presented the prescription for Tramadol tablets. For how long such a prescription must be kept at a pharmacy?
5 years, exclusive of the current year
6 months, exclusive of the current year
10 years, exclusive of the current year naЕ.01 month, exclusive of the current year
1 year, exclusive of the current year
45 із 200
A 6-year-old child with pneumonia had been administered an antibiotic. After treatment the child lost the hearing. What group of antibiotics might have caused this complication?
Aminoglycosides
Natural penicillins
Cephalosporins
Semi-synthetic penicillins
Macrolides
46 із 200
Suppositories are prepared by various methods such as rolling, pouring, pressing. What base is used in the pouring method?
Butyrolum
Cocoa butter
Paraffin
Vaseline
Coriander oil
47 із 200
Select the optimal antibacterial drug for the treatment of mycoplasma pneumonia:
Rovamycin
Penicillin
Gentamicin
Amoxiclav
Ampicillin
48 із 200
Quantitative determination of pesticides in organic extracts after the isolation from the biological material can be done by various methods. What method of quantitative analysis of chlorophos is based on measuring the peak height parameter?
Gas-liquid chromatography
Biochemical method
Argentometry
Photometry
Thin-layer chromatography
49 із 200
An analytical chemist of the quality control department of a pharmaceutical plant has to determine the average weight of glibenclami-de tablets. How many tablets should be tested for this purpose?
20
50
5
30
10
50 із 200
A pharmacy received 10 kg of hawthorn tincture which was packaged in 80 ml bottles. This operation should be recorded in the following document:
Journal of laboratory and prepacking operations
Consolidated register
Cashbook
Formulation journal
Receipt for the ordered medication
51 із 200
Employees of a pharmacy receive hourly rate wage and bonuses based on individual performance. What document is issued when calculating the payroll advance?
Payroll record
Inventory report
Cash receipt voucher
Cash payment voucher
Invoice
52 із 200
Help a medical student to select an adrenergic drug for the treatment of anaphylactic shock:
Epinephrine hydrochloride
Clonidine
Fenoterolum
Galazolin
Isadrinum
53 із 200
A 5-year-old child had accidentally drunk a bottle of eye drops. After 30 minutes the child developed shortness of breath, difficult swallowing, voice hoarseness, dilated pupils, hyperthermia. Which of the drugs might have induced the described manifestations?
Atropine
Adrenaline
Novocaine
Pilocarpine
Mesatonum
54 із 200
A patient purchased peppermint leaves at a pharmacy. What recommendations on infusing this herbal raw material must be given by the pharmaceutist?
The infusion is to be prepared in a tightly closed vessel
The extract is to be immediately filtered after infusing
The infusion is to be prepared on an open fire
The extract is to be artificially cooled 15 minutes after infusing
The infusion is to be prepared at room temperature
55 із 200
It is required to prepare 50 g of zinc ointment for a patient. What amount of zinc and vaseline must be weighed out by a pharmaceutist?
5,0 and 45,0 g
1,0 and 49,0 g
0,5 and 49,5 g
2,5 and 40,0 g
10,0 and 40,0 g
56 із 200
Sterilization methods applied for the preparation of drugs under aseptic conditions can be differentiated into physical, mechanical, and chemical ones. Specify the chemical method of sterilization:
Addition of preservatives
Pressure steam sterilization
Dry heat sterilization
UV light sterilization
Radiation sterilization
57 із 200
A patient had been given an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient developed red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucosa. What is the cause of this complication?
Immediate allergy
Tachyphylaxis
Local irritation
Withdrawal syndrome
Delayed allergy
58 із 200
What is the mechanism of action of diclofenac sodium?
It blocks cyclooxygenase
It activates adenylate cyclase
It activates the synthesis of phosphodiesterase
It inhibits phosphodiesterase
It inhibits cholinesterase
59 із 200
In order to identify deoxycorticosterone acetate a pharmaceutical analyst performed a steroid cycle reaction which produced cherry-red color and green fluorescence. What reagent was added?
Concentrated sulfuric acid
Potassium hydroxide solution
Iodine solution
Iron (III) chloride solution
Chloroform
60 із 200
When investigating the case of drug intoxication, the expert commission should find out, whether intoxication had been caused by opium or omnopon. For this purpose it is required to conduct an addititional test for:
Meconic acid and meconin
Thebaine
Papaverine
Codeine
Morphine
61 із 200
Within an accounting period a pharmacy has been providing the population with the finished medications. What business transaction will have an effect on increasing inventory of the pharmacy?
Arrivals from the pharmaceutical warehouse
Markdown according to the prepacking journal
Write-off of low-value inventory
Salary accounting
Write-off of goods
62 із 200
Which of the following nonsteroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?
Nimesulide
Piroxicam
Diclofenac
Acetylsalicylic acid
Indomethacin
63 із 200
A manufacturing enterprise plans to retail a new drug through the corporate network of pharmacies. What strategy of drug distribution will be used?
Direct
Horizontal integration
Flexible
Multi-echelon
Vertical integration
64 із 200
When preparing an ointment with castor oil and vaseline a pharmaceutist failed to obtain a homogeneous system. What is the most likely cause of incompatibility between these components?
Immiscibility of the ingredients
Limited solubility
Release of water of crystallization
Adsorption
Coagulation
65 із 200
In order to identify the toxic substance which was extracted from the acidic aqueous extract by an organic solvent, a toxicologist performed a murexide test which resulted in development of pink coloration. This indicates presence of the following substance in the sample:
Barbamyl
Atropine
Morphine
Strychnine
Cocaine
66 із 200
Woolly foxglove is used as raw material for the production of the following drug:
Lantosidum
Digitoxin
Erysimosidum
Corglycon
Adonizid
67 із 200
A 60-year-old female patient has a history of essential hypertension (stage II), ischemic heart disease, bronchial asthma. After the correction of pharmacotherapy, a patient experienced an attack of bronchospasm, and an escalation of dyspnea. What drug had caused the complication?
Propranolol
Mucaltinum
Aminophylline
Nifedipine
Salbutamol
68 із 200
A pharmaceutical analyst with a 6-year length of service is on a sick leave due to temporary disability. He is entitled to the sickness allowance in the amount of:
80% of average wage
30 % of average wage
70 % of average wage
100 % of average wage
50 % of average wage
69 із 200
Sage leaves procured for the production of essential oil should be dried at a temperature of:
25-30° C
70-80 °C
100 °C
60-70 °C
50-60 °C
70 із 200
Which of the following antibiotics can be identified by means of the maltol formation test?
Streptomycin sulfate
Kanamycin monosulfate
Amoxicillin
Doxycycline hydrochloride
Lincomycin hydrochloride
71 із 200
What is the main mechanism of action that underlies the bactericidal effect of penicillin on the coccal flora?
Disruption of synthesis of the microbial cell wall
Damage to the cytoplasmic membrane permeability
Activation of the immune system of the macroorganism
Inhibition of protein synthesis
Phagocytic activity of leukocytes
72 із 200
What is the drug of choice for the treatment of acute pyelonephritis in a pregnant woman in the I trimester?
Amoxicillin
Norfloxacin
Gentamicin
Biseptolum
Chloramphenicol
73 із 200
What is the most suitable drug that can be recommended for the treatment of rhinitis accompanying an ARVI in a 7-month-old child?
0,9% warm water solution of NaCl
Galazolin
Pinosol
Naphthyzin
Boromentol ointment
74 із 200
What drug may cause the development of constipation in patients undergoing combined therapy for arterial hypertension?
Verapamil
Pananginum
Furosemide
Trimetazidine
Acetylsalicylic acid in small doses
75 із 200
In a pharmaceutical company both American and Japanese management styles are used. Select a characteristic feature of the Japanese management style:
Collective responsibility
Clearly formalized management structure
Short-term employment
Fast evaluation and career advancement
Individual decision-making process
76 із 200
Drug A is in the stage of market saturation. In order to push up intensive sales, management of the manufacturing company decided to use the following type of advertising:
Aggressive
Sales promotion
Informational
Public relations
Personal sales
77 із 200
A person got poisoned with alcohols. What alcohol derivatives are used for the analysis by the method of gas-liquid chromatography?
Alkyl nitrites
Alkyl sulfates
Alkyl sulfites
Alkyl nitrates
Alkyl acetates
78 із 200
A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the analyte?
Tartaric acid
Potassium permanganate
Zinc oxide
Iron (III) chloride
Sodium hydroxide
79 із 200
A pharmaceutical analyst tests potassium bromide for magnesium and alkaline earth metals impurity. What solution is used for this purpose?
Sodium edetate
Potassium permanganate
Hydrochloric acid
Sodium nitrite
Silver nitrate
80 із 200
A patient with a history of essential hypertension has been administered lisinopril. What is the mechani- sm of action of this drug?
It inhibits ACE
It inhibits alpha-adrenergic receptors
It inhibits M-cholinergic receptors
It stimulates beta-adrenergic receptors
It inhibits beta-adrenergic receptors
81 із 200
A male patient has been administered an antiulcerant that blocks histamine receptors of the gastric mucosa. What drug is it?
Famotidine
Atropine sulfate
Omeprazole
Almagelum
Pirenzepine
82 із 200
Stimulation of beta-cells of the pancreas causes the hypoglycemic effect of the following drug:
Glibenclamide
Heparin
Prednisolone
Adrenaline hydrochloride
Retabolilum
83 із 200
A pharmaceutist prepared an ointment by the following formulation: Rp.: Tannini 0,2 Lanolini 3,0 Vaselini 10,0 M. utf. ung.
Water dissolution, emulsification with anhydrous lanolin
Dissolution in molten vaseline
Trituration with an alcohol in a mortar, blending with the base F. Dissolution in liquid petrolate
S. To anoint the affected skin areas. What method of tannin incorporation was used?
Trituration with liquid petrolate in a mortar by Deryagin rule
84 із 200
Business transactions are displayed in the accounts. The entry in the account ledger that is made to record the incoming of economic resources is called:
Debit
Assets
Equity
Liabilities
Credit
85 із 200
Within the matrix of Boston Consulting Group, a certain drug refers to a group of products called 'milking cash cows'. Specify the stage of the lifecycle of this drug:
Maturity
Introduction
Growth
Decline
Withdrawal
86 із 200
An analytical laboratory has been commissioned to prove the presence of ethylenediamine in aminophylli-ne. Which of the following reagents makes it possible to detect ethylenedi-amine?
Copper (II) sulfate
Concentrated sulfuric acid
Sodium hydroxide
Barium chloride
Silver nitrate
87 із 200
A patient has glaucoma. Recommend him a drug of the M-cholinomimetic group:
Pylocarpine hydrochloride
Atropine sulfate
Ephedrine hydrochloride
Laevomycetin
Sulfacyl sodium
88 із 200
Advise an internship doctor on why iron preparations should not be administered together with antacids:
This causes malabsorption of iron
This accelerates elimination of iron preparations
This increases intoxication with iron preparations
This prevents deposition of iron in the body
This causes increased binding to blood proteins
89 із 200
A female patient with pneumonia has been administered doxycycline hydrochloride. This drug relates to the following group of antibiotics:
Tetracyclines
Cephalosporins
Penicillins
Aminoglycosides
Macrolides
90 із 200
A pharmacy received the goods according to the accompanying documentation. Who is responsible for keeping the record of medicines received by a business entity?
Authorized representative
Chief accountant
Trustee
Materially responsible person
Pharmacist of the pharmacy
91 із 200
Under the SPh of Ukraine, one of the reactions for the detection of calcium cation presence in drugs is the reaction with:
Glyoxal-hydroxyanil
Hydroxyquinoline
Alizarin
Sulfuric acid
Hydroxylamine
92 із 200
A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:
Ursodeoxycholic acid
Mefenamic acid
Gamma-aminobutyric acid
Citric acid
Acetylsalicylic acid
93 із 200
A patient with acute heart failure and cardiac glycoside intolerance was given an injection of dobutamine. What is the mechanism of its action?
Stimulation of в1-adrenoceptors
Stimulation of M-cholinergic receptors
Inhibition of phosphodiesterase
Block of K+-, Aa+-ATPase
Stimulation of a1 -adrenoceptors
94 із 200
Which of the methods to fill ampoules with injectable solutions makes it possible to protect capillaries from contamination with thick and viscous solutions?
Syringe
Vapor condensation
Squeezing-through
Vacuum
Turbo vacuum
95 із 200
When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the board members in a joint-stock company?
Limited to the value of their shares
Limited to the amount of deposits
Limited to the contributions to the statutory fund and their property
Unlimited and solidary
Limited to the double amount of deposits
96 із 200
In order to verify the purity of the essential oil, some ethanol was added into the test tube with peppermint oil. The mixture became turbid. This means that the peppermint oil contains the following impurity:
Fatty oil
Phenol
Acetone
Diethyl ether
Ethyl acetate
97 із 200
5 % solution of methylcellulose is used as a stabilizer for preparing a suspension of the following drug substance:
Terpine hydrate
Starch
Bismuth nitrate basic
Zinc oxide
Magnesium oxide
98 із 200
An analytical chemist of the quality control department of a pharmaceutical plant can prove the presence of the cation in the test substance with a solution of potassium:
Pyroantimonate
Hydroxide
Nitrate
Ferrocyanide (III)
Chloride
99 із 200
Magnesium peroxide identification is performed by the reaction of perchromic acid formation. What color is produced as a result of this reaction?
Blue
Black
Green
Yellow
Red
100 із 200
A forensic medicine laboratory received some biological material. It was to be tested for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:
Chloroform
Water acidified with sulfuric acid
Ethanol acidified with oxalic acid
Propanol acidified with oxalic acid
Water alkalized with ammonia solution
101 із 200
Pharmacies prepare injectable solutions. Which solution is prepared without any stabilizer?
Sodium bicarbonate solution
Glucose solution
Solution of caffeine sodium benzoate
Novocaine solution
Sodium thiosulfate solution
102 із 200
Ammifurinum contains furocumari-nes. These biologically active substances are derived from:
Fruits of large ammi
Fruits of common parsnip
Fruits of psoralea
Fruits of toothpick ammi
Rhizomes and roots of angelica
103 із 200
Quality of ampouled injection solutions is tested as to various parameters. How many ampullae are to be checked for assessing the quality of sealing (hermeticity)?
100%
50 %
75 %
80 %
97 %
104 із 200
A pharmacy compounds suspensions. What substance can be used for preparing a suspension without adding the stabilizer?
Magnesium oxide
Menthol
Camphor
Phenyl salycylate
Sulfur
105 із 200
All employees are entitled to annual leave. What is the duration of the additional leave for pharmacy employees with non-standard working hours?
Seven calendar days
Ten calendar days
Thirty calendar days
The additional leave is not granted
Twenty calendar days
106 із 200
One of the packagings stored at the warehouse of finished products has a damaged label. It is known that the drug substance in this packaging relates to alkaloids. In course of group qualitative tests for alkaloids the drug substance reacted positively with murexide. Further identification of the drug substance should be limited to the following group of derivatives:
Purine
Isoquinoline
Tropane
Quinoline
Indole
107 із 200
Industrial, labor and socioeconomic relations between the head of a pharmaceutical company and the employees are regulated by:
Collective agreement
Corporate code
Employment agreement
Statute
Contract
108 із 200
A pharmacy received the following formulation: Rp.: Dibazoli 0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose:
0,27
0, 25
0, 26
2, 7
0, 30
109 із 200
Xenobiotics are metabolized in the body. The main metabolite of the acetic acid is:
Acetaldehyde
Methyl alcohol
Isopentyl alcohol
Valeric acid
Formic acid
110 із 200
Under the SPhU, the pharmacopei-al preparation 'Aether anaestheti-cus'is not allowed to have peroxide impurity. What reagent should be used to detect peroxides?
Solution of starch and potassium iodide
Lugol’s reagent
Solution of starch and potassium tetraiodomercurate
Grade reagent
Solution of starch and potassium bromide
111 із 200
Arrangement of drugs in the retail space of a pharmacy can be characterized as either strong or weak. What arrangement of drugs is regarded as weak?
On the lower shelves
Cashier desk zone
The shelves on the right side as the buyers pass along
At the intersection of the ranks of shelves
Zones with a good frontal look
112 із 200
When calculating the personal income tax, the tax social privilege is taken into account. Its rate depends on a certain statutory amount. Specify this amount:
Minimum statutory wage
Cost of living for one person
Maximum payroll fund
Cost of living for children aged 6 to 18 years
Cost of living for incapacitated persons
113 із 200
Fatty oils containing unsaturated fatty acids are used for the prophylaxis of atherosclerosis. Specify the starting materials of herbal origin that contain fatty oil:
Pumpkin seed
Chestnut seed
Parsnip fruits
Ispaghula seed
Psoralea fruits
114 із 200
The phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different starting materials. Specify the biogenic stimulators of animal origin:
Vitreous body, placental suspension for injections, plasmolum, solcoseryl
Peloidinum, humisolum, torfotum, Fibs Rro injectionibus
Peloidinum, humisolum, torfotum, plasmolum, solcoseryl
Liquid aloe extract, aloe liniment, aloe juice, biossedum
Liquid aloe extract, aloe liniment, plasmolum
115 із 200
A pharmacy network received a batch of raw material without analysis protocol. It was identified as marshmallow root by the external charcteristics. The reaction with 5% alkali liquor was positive. This indi- cates the presence of:
Slimes
Cellulose
Starch
Pectins
Gums
116 із 200
A pharmaceutical analyst tests anhydrous glucose for purity according to the requirements of the SPhU. Inadmissible barium impurity can be detected by using the following acid:
Sulphuric
Perchloric
Nitric
Acetic
Hydrochloric
117 із 200
The chemical name 1-benzoyl-5-ethyl-5-phenyl-barbituric acid stands for the following substance relating to barbiturates:
Benzonal
Phenobarbital
Hexenal
Benzobamil
Barbital
118 із 200
What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?
Novopassit
Securinine nitrate
Ergotamine
Glaucine hydrochloride
Vinblastine
119 із 200
A pharmaceutist prepares 3000 mL of valerian root infusion for a hospital department. The given amount of extract should be infused in a water bath for:
25 minutes
30 minutes
10 minutes
45 minutes
15 minutes
120 із 200
A pharmaceutist has prepared a solution of menthol oil. Specify the dissolution temperature of the active substance:
40-50° C
20-30 °C
60-70 °C
70-80 ° C
30-40 °C
121 із 200
Forensic toxicological analysis of a mineralizate revealed copper. For the initial detection of copper ions the following substance is used:
Plumbum diethyldithiocarbamate
Diphenylamine
Diphenylcarbazide
Sodium diethyldithiocarbamate
Dithizone
122 із 200
A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?
Dichlorvos
Ethyl mercury chloride
DDT
Heptachlor
Hexachlorocyclohexane
123 із 200
As a result of condensation of substituted malonic esters and urea the derivatives of the following substance are obtained:
Pyrimidine
Pyrazine
Pyridazine
Pyridine
Pyrazole
124 із 200
Which of the following ophthalmic dosage forms is produced only industrially?
Ophthalmic inserts
Ophthalmic ointments
Eye washes
Eye rinses
Eye drops
125 із 200
What medication should be used as an antidote to eliminate the respiratory depression caused by an overdose of a narcotic analgesic?
Naloxone
Camphor
Cordiamine
Aethimizolum
Ammonia
126 із 200
Fenofibrate relates to the following pharmacological group:
Hypolipidemics
Hypnotics
Antihypertensives
Indirect anticoagulants
Fibrinolysis inhibitors
127 із 200
Which of the following vaginal dosage forms relate to the officinal formula, that is, are prepared in a pharmacy?
Pessaries
Vaginal capsules
Vaginal tablets
Vaginal foams
Vaginal tablets for preparing solutions and suspensions
128 із 200
The glidants aerosil or magnesium stearate together with talc are added to the excipients in hard gelatin capsules in order to facilitate the following property:
Powder flowability
Compactibility
Homogenity
Moisture regulation
Homogeneous mixing
129 із 200
A student has been prescribed a tonic. This may be the tincture of the following medicinal plant:
Rhodiola rosea
Common yarrow
Black locust
Java tea (orthosiphon aristatus)
Purple foxglove
130 із 200
A 25-year-old female patient had been taking antibiotics for 7 days, the disease was complicated by the development of intestinal dysbiosis. This complication should be treated by the drugs of the following group:
Probiotics
Choleretics
Antacids
Adaptogens
Antispasmodics
131 із 200
Which group of adjuvants includes polyvinyl alcohol used under the SPhU?
Prolongators
Antioxidants
Preservatives
Isotonizing agents
pH adjusters
132 із 200
Which of the following drugs should be used for prevention of bronchial asthma attacks?
Cromolyn sodium
Drotaverine
Salbutamol
Diphenhydramine hydrochloride
Ambroxol
133 із 200
A pharmaceutist has to prepare a medication by the following formulation: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place:
Mint water
Sodium benzoate
Sugar syrup
Sodium hydrogen carbonate
Liquoris Ammonii anisatis
134 із 200
A pharmaceutist prepares an ointment under aseptic conditions on the sterile ointment base, namely the composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technique of ointment preparation is typical for the following substance:
Benzylpenicillin sodium salt
Sodium chloride
Pilocarpine hydrochloride
Sodium sulfate
Thiamine chloride
135 із 200
Under the chemico-toxicological classification, toxic compounds are grouped according to the method of their isolation from the biological material. What compound can be isolated by steam distillation?
Chloral hydrate
Diazepam
Atropine
Analgene
Arsenicum
136 із 200
Toxic medicines are isolated from biological material at a certain pH level of the medium. What substance is extracted from acidic aqueous extracts?
Caffeine
Chlorpromazine
Cocaine
Morphine
Atropine
137 із 200
What drug is indicated in case of taking an overdose of depolarizing muscle relaxants?
Neostigmine methylsulfate
Naloxone
Magnesium sulfate
Unithiol
Metoprolol
138 із 200
A 20-year-old female patient has been administered bicillin for rheumatic fever prophylaxis. Specify the frequency of bicillin-5 administration:
Once every 3 weeks
Once per week
Once a day
Once per month
Once in 3 days
139 із 200
A 65-year-old male patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient takes dai- ly 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?
Glycoside intoxication
Tachyphylaxis
Hypersensitivity reaction
Withdrawal syndrome
Food poisoning
140 із 200
Vincamine alkaloid reduces blood pressure, has a pronounced sedation effect, as well as hemostatic and anti-inflammatory effect. What herb is the source of this alkaloid?
Common periwinkle
Yellow water-lily
Bluish larkspur
Northern wolfsbane
Thick-fruited pagoda tree
141 із 200
The galenical preparations workshop produces belladonna tincture. Specify the required ratio for this dosage form:
1:10
1:5
1:20
1:1
1:2
142 із 200
Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:
Polyethylene oxide
Hydrogenated fat
Methyl cellulose
Vaseline, lanolin
Silicon
143 із 200
A patient with acute heart failure has been administered an adrenomimetic agent. What drug is it?
Dobutamine
Corglycon
Digoxin
Metoprolol
Salbutamol
144 із 200
Oil liniments are produced with fatty oils used as a base. What kind of oil should be used by a pharmacist if it was not specified in the formulation?
Sunflower oil
Eucalyptus oil
Sesame oil
Petrolatum
Cod-liver oil
145 із 200
A pharmacy received a formula for an alcohol solution of methylene blue with unspecified alcohol concentration. In this case, a pharmacutist must use ethyl alcohol of the following concentration:
60%
96 %
70 %
40 %
90 %
146 із 200
Production unit for ampouled medicinal preparations produces procaine hydrochloride solution. This solution is stabilized by adding:
0,1 mol/l of hydrochloric acid solution
0,1 mol/l of sodium hydroxide solution
20,0 of sodium hydrogen carbonate
1,5 g of amino-propylene glycol
0,1 mol/l of sodium hydrogen carbonate solution
147 із 200
Recommend a drug for the treatment of tachyarrhythmia epi- sodes:
Propranolol
Adrenaline
Dobutamine
Atropine
Caffeine sodium benzoate
148 із 200
A 35-year-old female customer came to a pharmacy to purchase a medicine for the prevention of influenza. Which of the following drugs can be recommended?
Rimantadine
Lamivudine
Ganciclovir
Ribavirin
Acyclovir
149 із 200
Employees of a company can be instructed to go on a business trip by the orders of the company’s head. Specify the deadline for submission of an expense report after the employee’s return from the trip:
3 days
6 days
2 days
4 days
5 days
150 із 200
A pharmaceutical analyst analyzes a dosage form containing zinc sulfate. What reagent enables him to confirm the presence of the zinc cation in the analyte?
Sodium sulfide
Sodium tetraphenylborate
Potassium ferrocyanide
Ammonium chloride
Silver nitrate
151 із 200
Lily of the valley is widely regarded as a cardiac stimulant and sedative. During the raw material procurement, the following plant may occur in the harvested crop:
Round-leaved pyrola
Viola arvensis
Treacle-mustard (Erysimum chei-ranthoides)
Viola tricolor
Spring adonis
152 із 200
A pharmaceutist prepares an infusion at a ratio of 1:30. What herbal raw material will be used?
Lily of the valley grass
Sage leaves
Oak bark
Shoots of Marsh Labrador tea
Marshmallow root
153 із 200
A pharmaceutist has prepared vaginal suppositories. Specify the form of these suppositories:
Marbles
Cone
Sticks
Torpedo
Cylinder
154 із 200
Under the SPhU (appendix 2), leaves of ginkgo are standardized by the content of:
Flavonoids
Chromones
Alkaloids
Coumarins
Saponins
155 із 200
A clinical pharmaceutist invited to a medical conference made a report on the antiviral drug acyclovir. What is its mechanism of action?
It inhibits the synthesis of nucleic acids
It increases the permeability of the cell membrane
It blocks the synthesis of the cell wall
It antagonizes with PABA
It inhibits the synthesis of proteins
156 із 200
What kind of marketing is provided in case of negative demand for goods and services, that is, in a situation when the demand is absent in a substantial part of the potential market?
Conversion
Stimulating
Synchro marketing
Remarketing
Demarketing
157 із 200
Prescriptions for the controlled drugs dispensed under the reimbursement program (except for the narcotic and psychotropic preparations in substance) are issued on the following prescription form:
№1 in duplicate
№3 in duplicate
№1, single copy
№1 and № 3
№3, single copy
158 із 200
In case of the planned closure of a pharmacy for repair works, technical re-equipment or other works, a business entity is obliged to give a written notice to the Territorial State Inspectorate for Quality Control of Medicines in advance, but not later than:
5 days in advance
7 days in advance
12 days in advance
10 days in advance
3 days in advance
159 із 200
Pharmacy №7 is engaged in both sales and production. What operations ARE NOT REGISTERED in the journal of laboratory and prepacking works?
Extemporaneous compounding of dosage forms
Packaging of finished products in certain amounts
Preparation of commercially available medications
Preparation of concentrated solutions
Preparation of semi-finished products
160 із 200
Specify a drug having an analeptic and psychostimulant effect:
Caffeine sodium benzoate
Diclofenac sodium
Diazepam
Neostigmine methylsulfate
Corglycon
161 із 200
What medicines are used to eliminate bronchospasm?
в-adrenergic agonists
a-adrenergic agonists
Cholinesterase inhibitors
M-cholinomimetics
в-blockers
162 із 200
Alkaloid glaucine has an antitussive effect that is stronger and longer if compared to that of codeine, and exhibits no narcotic side effects. What medicinal plant contains glauci-ne?
Yellow hornpoppy
Henbane bell (Scopolia carniolica)
Celandine
Datura
Thermopsis lanceolata
163 із 200
Drug plant Dioscorea nipponi-ca is the starting materials for the production of Polysponinum drug which is used in the complex treatment of atherosclerosis. Specify the active compounds of dioscorea:
Steroid saponins
Essential oil
Cardiac glycosides
Alkaloids
Triterpene saponins
164 із 200
A hypertensive patient had been administered a diuretic as a part of the combined therapy. The administered drug caused hypokalemia. Specify this drug:
Hydrochlorothiazide
Amiloride
Triamterene
Spironolactone
Allopurinol
165 із 200
A pharmaceutical factory produces herbal juice from fresh raw material. What operation should be performed at the stage of juice purification?
Heating followed by rapid cooling
Sedimentation
Filtration
Crystallization
Adsorption
166 із 200
Cash receipts and payments at a pharmacy are recorded in the cashbook. Which of the following cash transactions IS NOT REGARDED as a receipt transaction?
Issuing funds to be accounted for
Recognizing cash receipts from sales at a pharmacy
Return of unused disbursement funds
Recognizing cash receipts from sales at pharmacy outlets and kiosks
Recognizing accrued salaries and advance payable
167 із 200
What system includes a set of legal rules that regulate the amounts, forms, methods and time limits for collecting taxes and tax-like charges that enable the state to perform its functions?
Tax
Statistic
Reporting
Accounting
Remuneration of labor
168 із 200
Phytochemical workshop of a factory manufactures pancreatin. What is the starting material for obtaining pancreatin?
Pancreas of pigs or cattle
Heart of cattle
Gastric mucosa of pigs
Lungs of cattle
Egg white
169 із 200
In case of simultaneous use of metronidazole and oral anticoagulants derived from coumarin patients must be warned about:
Potentiation of anticoagulants effect and the risk of bleeding
Potentiation of metronidazole effect
Higher neurotoxicity
Reduction of anticoagulants effect
Reduction of metronidazole effect
170 із 200
Specify the principle of the pharmacy accounting which complies with the following definition: 'This principle provides for continuous following the adopted accounting policy. Any changes to the accounting policy must be well-grounded and fixed in the financial statements':
Consistency
Periodicity
Full disclosure
Going concern
Expenses against revenues matching
171 із 200
At a maternity hospital a pregnant woman with weak uterine contractions has been administered oxytocin. This drug relates to the following pharmaceutical group:
Pituitary hormone preparations
Mineral corticoids
Thyroid hormone preparations
Anabolic steroids
Glucocorticoids
172 із 200
What factor underlies the mechanism of the analgesic effect of morphine hydrochloride?
Stimulation of opiate receptors
Inhibition of cholinesterase
Inhibition of phosphodiesterase
Stimulation of adenylate cyclase
Inhibition of histamine receptors
173 із 200
Analytical and control laboratory determines quality of fatty oils by using certain chemical indices. Specify the chemical index that is demonstrative of the fatty oil drying:
Iodine absorption number
Peroxide number
Saponification number
Acid number
Ester number
174 із 200
The head of a pharmaceutical company 'Azalea'applies different types of control. The control which starts with logging in to the system of organization before commencement of work and is exercised through rules, procedures, etc. refers to:
Preliminary control
Decentralized control
Final control
Current control
Centralized control
175 із 200
A 30-year-old male patient diagnosed with acute osteomyelitis has been administered an antibiotic that is highly effective in penetrating the bone tissue. What drug has been chosen?
Lincomycin
Penicillin
Ampicillin
Polymyxin-M
Bicillin 3
176 із 200
A pharmaceutist dispensed doxycycline to a patient and recommended to abandon dairy products. What is the reason for such recommendation?
Deceleration of the antibiotic absorption
Increase in the antibiotic toxicity
Dairy products are not digested
Increased risk of dysbiosis
Disruption of digestion process
177 із 200
Commercial and financial activity of a pharmacy involves using returnable tare. Which of the following containers are returned to the supplier?
Metal cylinders
Glassware
Paper boxes
Packaging materials
Glass-stoppered bottles
178 із 200
A pharmacy has a set of documents which confirm the ownership of computer programs. Specify the balance sheet item that shows the pharmacy’s property:
Intangible assets
Low-value equipment
Stock
Monetary assets
Goods
179 із 200
In order to expand its range of activities, pharmacy №12 purchased some manufacturing equipment. What group of economic resources does the manufacturing equipment relate to?
Fixed assets
Goods
Tara
Incomplete capital investments
Tangible assets
180 із 200
A pharmaceutical analyst added solutions of zirconyl nitrate and alizarin to a drug substance. The reaction produced red color turning into yellow. Specify the analyte:
Sodium fluoride
Sodium iodide
Sodium chloride
Sodium bromide
Sodium thiosulfate
181 із 200
A pharmaceutical company studies the market situation in terms of a relationship between supply and demand, price level, stock of goods, etc. What is the company’s actual object of study?
Market behaviour
Conditions for the market existence
Market structure
Market scope
Market infrastructure
182 із 200
During a medical briefing a pharmacy intern was asked about the mechanism of antiatherosclerotic effect of clofibrate (fenofibrate). What is the correct answer?
It lowers triglycerides
It binds bile acids in the small intestine
It inhibits the release of free fatty acids from adipose tissue
It has an antioxidant effect
It inhibits the cholesterol absorption
183 із 200
What style of behavior in conflict situations involves partial satisfaction of the interests of both parties by mutual concessions with due consideration of all pros and cons?
Compromise
Dominance
Evasion
Competition
Cooperation
184 із 200
A pharmacy received a formulation for an extemporaneously compounded dosage form. The formula includes phenobarbital compounded with other drugs. Specify the required prescription form:
Form № 1 in duplicate
Form № 2
Form № 1
Form № 2 in duplicate
Form № 3
185 із 200
A pharmacy has purchased a refrigerator and computer. These fixed assets are placed on the pharmacy’s balance sheet at the following value:
Historic
Amortized
Residual
Market
Liquidating
186 із 200
Galenic preparations are produced with the use of various extractants. What extractants require pressure as a prior condition for the extraction process?
Liquefied gases
Vegetable oils
Dichloroethane, chloroform
Methyl alcohol, acetone
Ethanol
187 із 200
In the production of dry extracts the drying of purified extracts may not involve condensation of the the liquid extractions. What equipment should be used in this case?
Spray drier
Vacuum oven
Thermostat
Rotary one-flow drier
Shelf drier
188 із 200
Buckthorn bark is used as a laxative. Specify the period for procurement of raw material of alder buckthorn bark:
Spring, during the circulation of sap
The period of full ripeness
Autumn
Winter
Frondescence
189 із 200
A pharmacy received a prescription for phenobarbital tablets written out by a physician of the city clinic to an epileptic patient. Prescripti- ons for this drug must be written out on the following prescription form:
Form № 3 and № 1 in a single copy
Form № 1 in duplicate
Form № 3 in duplicate
Form № 1 in a single copy
Form № 2
190 із 200
A pharmaceutical analyst has to test the substance of iron sulfate heptahydrate for purity. What reagent should be used to detect zinc cation in the substance?
Potassium ferrocyanide
Silver nitrate
Barium chloride
Ammonium oxalate
Sodium tetraphenylborate
191 із 200
A pharmaceutical analyst performs the identification of phthalylsulphathiazole (phthalazol). In compliance with the SPhU requirements, the substance is to be heated with resorcinol in the presence of sulfuric acid. The subsequent addition of sodium hydroxide and water results in:
Intensive green fluorescence
Red-violet color
Abundant white precipitate
Intensive blue color
Extensive yellow precipitate
192 із 200
Under the SPhU, presence of ammonium salts in sodium tetraborate can be detected by method A by using a solution of the following substance:
Alkaline potassium tetrai-odomercurate
Silver nitrate
Sodium tetraphenylborate
Barium chloride
Potassium ferrocyanide
193 із 200
A pharmaceutical analyst performs the identification test of lidocaine hydrochloride under the SPhU. The identity is determined by the melting point of precipitate which is produced as a result of reaction with a solution of the following acid:
Picric
Thioglycolic
Phosphoric
Citric
Acetic
194 із 200
A pharmaceutist with 10 years of service legth is on a sick leave due to temporary disability. What allowance is he entitled to?
100% of the average wage
80 % of the average wage
60 % of the average wage
40 % of the average wage
70 % of the average wage
195 із 200
Pharmacy cashier is responsible for recording all credit and debit transactions. To enter into the books the cash received, a cashier should issue:
Cash receipt voucher
Cash payment voucher
Goods delivery note
Receipt note
Goods receipt note
196 із 200
Organizational form of business in which a company does not produce goods or services itself but owns other companies’ controlling stake and thereby supervises their activity is called:
Holding
Syndicate
Conglomerate
Cartel
Trust
197 із 200
The head of a wholesale pharmaceutical company applies modern theories in order to effectively motivate sales staff and determine the amount of remuneration. Specify one of the groups of motivation theories:
Process
Structural
Primary
System
Secondary
198 із 200
Which of these drugs kept in the pharmacy stock relates to the group of laxatives?
Bisacodyl
Morphine
Vicasol
Heparin
Atropine
199 із 200
A pharmacy received a batch of chemotherapeutic agents. Select an antiviral drug:
Acyclovir
Benzylpenicillin sodium salt
Isoniazid
Rifampicin
Doxycycline
200 із 200
A 40-year-old patient has a history of bronchial asthma and heart rhythm disorders in form of bradyarrhythmia. Bronchospasm can be eliminated by the drugs of the following pharmacological group:
M-cholinergic antagonists
в-blockers
Muscle relaxants
M-cholinomimetics
Cholinesterase inhibitors