Step 2 - Pharmacy 2014

A sample of biological material contains mercury. Specify the method of mercury isolation:

Destruction

Isolation by organic solvents

Isolation by acidified alcohol

Mineralization

Steam distillation

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A pharmaceutist has to prepare an oil emulsion with menthol. Specify the appropriate way of the active substance incorporation:

Dissolution in oil

Dispersion with the addition of ready emulsion

Dissolution in water intended for diluting the primary emulsion

Incorporation into the ready primary emulsion

Dissolution in the ready emulsion by heating

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It is required to prepare a decoction of bearberry leaves. Specify the ratio of raw materials to the extractant if not indicated in the formulation:

1:20

1:30

1:400

1:5

1:10

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A pharmaceutist prepared an injectable solution of novocaine. What stabilizer had been used?

Sodium sulfite solution

Stabilizator of Weibel

Hydrochloric acid solution

Sodium bicarbonate solution

Sodium thiosulfate solution

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A disabled veteran of the WW2 has been prescribed codeine powder. What is the maximum permissible amount of codeine that can be dispensed by the prescription?

0, 6

0,2

1, 2

0, 1

1, 0

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Certain groups of drugs are subject to strict record keeping and storage in pharmacies. Specify a drug that relates to the group of narcotics:

Dicaine

Analgene

Ethylmorphine hydrochloride

Dephedrinum

Clonidine

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Under the analytical normative documents, atropine sulfate should be titrated with hydrochloric acid solution in the anhydrous acetic acid medium in the presence of the following indicator:

Methyl orange

Phenolphtalein

Methylene blue

Crystal violet

Thymol blue

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Losartan as a part of treatment of arterial hypertension is contraindicated in case of:

Hyperglycemia

Urine acid diathesis

Hypokalemia

Hyperlipidemia

Pregnancy

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Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?

Phenylinum

Acetylsalicylic acid

Heparin

Streptokinase

Ticlopidine

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At the end of the dug action drug addicts develop severe mental, neurological and somatic disorders. This complex of symptoms is called:

Sensibilization

Tolerance

Cumulation

Withdrawal syndrome

Tachyphylaxis

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Patients with heart failure caused by persisting cardiac and coronary vessel dysfunction can be recommended preparations produced from the following herbal raw material:

Calendula flowers

Aralia roots

Ginseng roots

Barberry roots

Hawthorn fruits

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Rutin exhibits P-vitamin activity. What medicinal plant is used as starting materials for the industrial production of rutin?

Herba Polygoni avicularis

Fructus Hippophaes rhamnoides

Herba Bidentis tripartitae

Fructus Sophorae japonicae

Flores Helichrysi arenarii

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A patient came to a pharmacy to purchase cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?

Herba Achilleae millefolii

Rizoma Calami

Radix Taraxaci officinalis

Folium Uvae ursi

Rizoma et radix Sanquisorbae officinalis

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Pharmaceutical warehouse received a batch of herbal raw material of cinnamon rose. Under the State Pharmacopoeia, it is required to test this raw material for the following active substances:

Tannins

Anthracene derivatives

Essential oil

Ascorbic acid

Flavonoids

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Under the analytical normative documents, prior to direct bromatometric determination of arsenous acid anhydride the following substance should be added to the analyzed solution:

Potassium nitrate

Sodium hydroxide

Sodium chloride

Potassium bromide

Sodium thiosulfate

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A pharmaceutical analyst of an analytical laboratory performs quantitative determination of silver nitrate by thiocyanatometry. What indicator is used in this case?

Phenolphtalein

Iron (III) ammonium sulphate

Starch

Sodium eosinate

Potassium chromate

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A pharmaceutical company produces concentrated extracts. Specify the concentration of ethanol in the extractant required for the production:

70-90 %

70-75 %

90-96 %

20-40%

50-60 %

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A factory workshop producing suspensions and emulsions is going to start manufacturing new drugs. What equipment can be used for the ultrasound processing of drugs?

Disintegrator, liquid whistle

Liquid whistle, magnetostrictive source

Dismembrator, electrical impulse plasmolyzer

Rotor-pulsation apparatus, di-smembrator

Centrifugal mixer with rotating housing

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The ointment workshop of a pharmaceutical plant launches production of a new ointment. Specify the manufacturing operation that ensures equal distribution of the drug substance in the base:

Homogenization

Pre-packing

Preparation of the base

Packaging

Standardization

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The aerosol workshop of a pharmaceutical plant uses various groups of propellants in the production. What propellants relate to the group of volatile organic solvents?

Vinyl and methyl chloride

Carbon dioxide

Freon (CFCs)

Methylene chloride, ethylene chloride

Propane, butane, isobutane

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The phytochemical workshop of a pharmaceutical plant manufactures liquid extracts. How many volume parts of the liquid extract can be produced from one weight part of herbal raw material in compliamce with the State Pharmacopoeia?

1 part

10 parts

0,5 part

3 parts

5 parts

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An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?

Chelatometry

Mercurimetric determination

Bromatometry

Nitritometric determination

Iodometry

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A chemist of the production unit for ampouled medicinal preparations analyzes injectable solution of calcium chloride. According to the requirements, the analyzed solution should be colorless. To meet this requirement, the analyte should be compared to:

Hydrochloric acid

Alcohol

Acetone

Water

Chloroform

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What drug is used as the specific antidote in case of intoxication with iron preparations?

Protamine sulfate

Bemegride

Deferoxamine

Atropine

Penicillamine

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Specify the type of capsules which are used for dispensing camphor powders:

Paraffin

Common paper

Waxed

Parchment

Cellophane

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A pharmacy received a formulation for an extemporaneously compounded medication. Specify the document that is used to set the price for such medication:

Cash receipt voucher

Retail price list for drugs

Certificate of quality

Certificate of analysis

Inventory report

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A pharmaceutist has prepared a suspension ointment. Specify the substance used for this type of ointments:

Menthol

Protargolum

Zinc oxide

Ichthyol

Potassium iodide

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Ergot (Secale cornutum) is used as an uterotonic agent in obstetric practice and for the treatmet of cardiovascular diseases. The authenticity of the raw materials is proved by the content of:

Reserpine

Hyoscyamine

Atropine

Ergotoxine

Ajmaline

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Among the given principles of market segmentation select a principle that is used in the study of drug market most often:

Socio-economic

Psychological

Behavioral

Demographic

Psychographic

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Personnel records refer to the following type of documents:

Pharmaceutical

Reference information

Directive

Scientific

Managerial

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A pharmacy received a formulation for eye drops containing 1% solution of pilocarpine hydrochloride. What substance should be used to ensure that the resultant solution is isotonic?

Boric acid

Glucose

Sodium nitrate

Sodium chloride

Sodium sulfate

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A pharmaceutist prepared 10 powders containing atropine sulfate in an amount of 0,00005 per dose. What trituration had been used?

1:10

1:100

1:1000

1:50

1:20

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Which of the following antihypertensive drugs has potassiumsparing effect?

Prazosin

Triamterene

Furosemide

Diltiazem

Metoprolol

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Immunochemical test for detection of opiates in urine is carried out on polystyrene plates with the use of horseradish peroxidase as a label. This method is classified as:

Homogeneous immunofluorescence

Heterogeneous radioimmunoassay

Heterogeneous immunoassay

Heterogeneous immunofluorescence

Homogeneous immunoassay

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When developing the system of marketing communications, a company should consider the characteristics of each tool used for market promotion of a drug. Which of the following characteristics is typical for advertising?

All answers are correct

There is no correct answer

Depersonalization (non-personal communication)

Two-way communication

Non-mass communication

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Quantitative determination of pyridine derivatives is performed by acidimetry in nonaqueous medium. What titrant is used for this purpose?

Sodium hydroxide

Sodium thiosulfate

Perchlorate acid

Nitric acid

Sulfuric acid

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What antiprotozoal agent can be recommended to a female patient with trichomoniasis?

Chiniofonum

Primaquine

Chloridinum

Metronidazole

Solusurminum

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A patient has a history of chronic bronchitis. Recommend him an expectorant which can be purchased at a pharmacy to facilitate the expectoration of thick and viscous mucus:

Glauvent

Ambroxol

Falimint

Libexin

Salbutamol

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What drug from the group of cardiac glycosides can be used as an alternative for strophanthine if it is not available at a pharmacy?

Celanidum

Isolanidum

Adonisidum

Corglycon

Digitoxin

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A pharmacy received the following formulation: Rp.: Xeroformii Picis Liquidae Betulae Olei Ricini 100,0 M.D.S. For wound anointing. Specify the dosage form:

Solution

Paste

Hydrophilic ointment

Liniment

Combined ointment

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What is the most common symptom of atropine intoxication?

Hyperhidrosis

Mydriatic pupils with no light response

Bradycardia

Myotic pupils with no light response

Reduction of intraocular pressure

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In order to detect the presence of thiosulfate ions a pharmaceutical analyst added the excess reagent. The resulting reaction produced a white precipitate which was slowly turning yellow, then brown, and black. What solution was added?

Barium chloride

Lead (II) acetate

Diphenylamine

Ammonium oxalate

Silver nitrate

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Quantitative analysis of boric acid can be performed by alkalimetric titration in the presence of:

Ammonia buffer

Mercury (II) acetate

Mannitol

Ethyl alcohol

Nitric acid

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A customer came to a pharmacy and presented the prescription for Tramadol tablets. For how long such a prescription must be kept at a pharmacy?

6 months, exclusive of the current year

10 years, exclusive of the current year naЕ.01 month, exclusive of the current year

5 years, exclusive of the current year

1 year, exclusive of the current year

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A 6-year-old child with pneumonia had been administered an antibiotic. After treatment the child lost the hearing. What group of antibiotics might have caused this complication?

Aminoglycosides

Cephalosporins

Macrolides

Natural penicillins

Semi-synthetic penicillins

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Suppositories are prepared by various methods such as rolling, pouring, pressing. What base is used in the pouring method?

Paraffin

Coriander oil

Cocoa butter

Butyrolum

Vaseline

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Select the optimal antibacterial drug for the treatment of mycoplasma pneumonia:

Penicillin

Gentamicin

Rovamycin

Ampicillin

Amoxiclav

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Quantitative determination of pesticides in organic extracts after the isolation from the biological material can be done by various methods. What method of quantitative analysis of chlorophos is based on measuring the peak height parameter?

Argentometry

Thin-layer chromatography

Photometry

Biochemical method

Gas-liquid chromatography

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An analytical chemist of the quality control department of a pharmaceutical plant has to determine the average weight of glibenclami-de tablets. How many tablets should be tested for this purpose?

10

30

50

20

5

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A pharmacy received 10 kg of hawthorn tincture which was packaged in 80 ml bottles. This operation should be recorded in the following document:

Cashbook

Journal of laboratory and prepacking operations

Consolidated register

Receipt for the ordered medication

Formulation journal

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Employees of a pharmacy receive hourly rate wage and bonuses based on individual performance. What document is issued when calculating the payroll advance?

Cash payment voucher

Invoice

Inventory report

Cash receipt voucher

Payroll record

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Help a medical student to select an adrenergic drug for the treatment of anaphylactic shock:

Epinephrine hydrochloride

Galazolin

Fenoterolum

Isadrinum

Clonidine

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A 5-year-old child had accidentally drunk a bottle of eye drops. After 30 minutes the child developed shortness of breath, difficult swallowing, voice hoarseness, dilated pupils, hyperthermia. Which of the drugs might have induced the described manifestations?

Novocaine

Mesatonum

Adrenaline

Pilocarpine

Atropine

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A patient purchased peppermint leaves at a pharmacy. What recommendations on infusing this herbal raw material must be given by the pharmaceutist?

The extract is to be artificially cooled 15 minutes after infusing

The infusion is to be prepared at room temperature

The infusion is to be prepared on an open fire

The extract is to be immediately filtered after infusing

The infusion is to be prepared in a tightly closed vessel

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It is required to prepare 50 g of zinc ointment for a patient. What amount of zinc and vaseline must be weighed out by a pharmaceutist?

0,5 and 49,5 g

2,5 and 40,0 g

1,0 and 49,0 g

5,0 and 45,0 g

10,0 and 40,0 g

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Sterilization methods applied for the preparation of drugs under aseptic conditions can be differentiated into physical, mechanical, and chemical ones. Specify the chemical method of sterilization:

UV light sterilization

Addition of preservatives

Radiation sterilization

Dry heat sterilization

Pressure steam sterilization

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A patient had been given an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient developed red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucosa. What is the cause of this complication?

Delayed allergy

Tachyphylaxis

Local irritation

Withdrawal syndrome

Immediate allergy

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What is the mechanism of action of diclofenac sodium?

It inhibits phosphodiesterase

It blocks cyclooxygenase

It activates the synthesis of phosphodiesterase

It activates adenylate cyclase

It inhibits cholinesterase

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In order to identify deoxycorticosterone acetate a pharmaceutical analyst performed a steroid cycle reaction which produced cherry-red color and green fluorescence. What reagent was added?

Iodine solution

Potassium hydroxide solution

Iron (III) chloride solution

Concentrated sulfuric acid

Chloroform

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When investigating the case of drug intoxication, the expert commission should find out, whether intoxication had been caused by opium or omnopon. For this purpose it is required to conduct an addititional test for:

Papaverine

Meconic acid and meconin

Morphine

Thebaine

Codeine

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Within an accounting period a pharmacy has been providing the population with the finished medications. What business transaction will have an effect on increasing inventory of the pharmacy?

Arrivals from the pharmaceutical warehouse

Markdown according to the prepacking journal

Salary accounting

Write-off of low-value inventory

Write-off of goods

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Which of the following nonsteroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?

Indomethacin

Nimesulide

Diclofenac

Piroxicam

Acetylsalicylic acid

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A manufacturing enterprise plans to retail a new drug through the corporate network of pharmacies. What strategy of drug distribution will be used?

Flexible

Multi-echelon

Direct

Horizontal integration

Vertical integration

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When preparing an ointment with castor oil and vaseline a pharmaceutist failed to obtain a homogeneous system. What is the most likely cause of incompatibility between these components?

Release of water of crystallization

Coagulation

Adsorption

Limited solubility

Immiscibility of the ingredients

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In order to identify the toxic substance which was extracted from the acidic aqueous extract by an organic solvent, a toxicologist performed a murexide test which resulted in development of pink coloration. This indicates presence of the following substance in the sample:

Morphine

Barbamyl

Atropine

Strychnine

Cocaine

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Woolly foxglove is used as raw material for the production of the following drug:

Digitoxin

Lantosidum

Adonizid

Corglycon

Erysimosidum

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A 60-year-old female patient has a history of essential hypertension (stage II), ischemic heart disease, bronchial asthma. After the correction of pharmacotherapy, a patient experienced an attack of bronchospasm, and an escalation of dyspnea. What drug had caused the complication?

Salbutamol

Aminophylline

Nifedipine

Propranolol

Mucaltinum

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A pharmaceutical analyst with a 6-year length of service is on a sick leave due to temporary disability. He is entitled to the sickness allowance in the amount of:

30 % of average wage

70 % of average wage

100 % of average wage

50 % of average wage

80% of average wage

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Sage leaves procured for the production of essential oil should be dried at a temperature of:

70-80 °C

25-30° C

100 °C

60-70 °C

50-60 °C

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Which of the following antibiotics can be identified by means of the maltol formation test?

Lincomycin hydrochloride

Amoxicillin

Streptomycin sulfate

Kanamycin monosulfate

Doxycycline hydrochloride

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What is the main mechanism of action that underlies the bactericidal effect of penicillin on the coccal flora?

Phagocytic activity of leukocytes

Disruption of synthesis of the microbial cell wall

Inhibition of protein synthesis

Activation of the immune system of the macroorganism

Damage to the cytoplasmic membrane permeability

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What is the drug of choice for the treatment of acute pyelonephritis in a pregnant woman in the I trimester?

Norfloxacin

Amoxicillin

Chloramphenicol

Biseptolum

Gentamicin

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What is the most suitable drug that can be recommended for the treatment of rhinitis accompanying an ARVI in a 7-month-old child?

Naphthyzin

Boromentol ointment

0,9% warm water solution of NaCl

Galazolin

Pinosol

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What drug may cause the development of constipation in patients undergoing combined therapy for arterial hypertension?

Verapamil

Acetylsalicylic acid in small doses

Furosemide

Trimetazidine

Pananginum

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In a pharmaceutical company both American and Japanese management styles are used. Select a characteristic feature of the Japanese management style:

Short-term employment

Individual decision-making process

Fast evaluation and career advancement

Clearly formalized management structure

Collective responsibility

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Drug A is in the stage of market saturation. In order to push up intensive sales, management of the manufacturing company decided to use the following type of advertising:

Public relations

Personal sales

Aggressive

Sales promotion

Informational

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A person got poisoned with alcohols. What alcohol derivatives are used for the analysis by the method of gas-liquid chromatography?

Alkyl nitrates

Alkyl sulfites

Alkyl sulfates

Alkyl acetates

Alkyl nitrites

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A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the analyte?

Potassium permanganate

Sodium hydroxide

Tartaric acid

Zinc oxide

Iron (III) chloride

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A pharmaceutical analyst tests potassium bromide for magnesium and alkaline earth metals impurity. What solution is used for this purpose?

Sodium edetate

Silver nitrate

Hydrochloric acid

Sodium nitrite

Potassium permanganate

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A patient with a history of essential hypertension has been administered lisinopril. What is the mechani- sm of action of this drug?

It inhibits M-cholinergic receptors

It inhibits beta-adrenergic receptors

It inhibits ACE

It inhibits alpha-adrenergic receptors

It stimulates beta-adrenergic receptors

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A male patient has been administered an antiulcerant that blocks histamine receptors of the gastric mucosa. What drug is it?

Omeprazole

Pirenzepine

Almagelum

Atropine sulfate

Famotidine

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Stimulation of beta-cells of the pancreas causes the hypoglycemic effect of the following drug:

Prednisolone

Retabolilum

Glibenclamide

Adrenaline hydrochloride

Heparin

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A pharmaceutist prepared an ointment by the following formulation: Rp.: Tannini 0,2 Lanolini 3,0 Vaselini 10,0 M. utf. ung.

Trituration with liquid petrolate in a mortar by Deryagin rule

Trituration with an alcohol in a mortar, blending with the base F. Dissolution in liquid petrolate

Dissolution in molten vaseline

Water dissolution, emulsification with anhydrous lanolin

S. To anoint the affected skin areas. What method of tannin incorporation was used?

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Business transactions are displayed in the accounts. The entry in the account ledger that is made to record the incoming of economic resources is called:

Equity

Credit

Debit

Liabilities

Assets

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Within the matrix of Boston Consulting Group, a certain drug refers to a group of products called 'milking cash cows'. Specify the stage of the lifecycle of this drug:

Maturity

Withdrawal

Decline

Introduction

Growth

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An analytical laboratory has been commissioned to prove the presence of ethylenediamine in aminophylli-ne. Which of the following reagents makes it possible to detect ethylenedi-amine?

Sodium hydroxide

Concentrated sulfuric acid

Barium chloride

Silver nitrate

Copper (II) sulfate

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A patient has glaucoma. Recommend him a drug of the M-cholinomimetic group:

Pylocarpine hydrochloride

Atropine sulfate

Sulfacyl sodium

Laevomycetin

Ephedrine hydrochloride

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Advise an internship doctor on why iron preparations should not be administered together with antacids:

This prevents deposition of iron in the body

This increases intoxication with iron preparations

This causes increased binding to blood proteins

This accelerates elimination of iron preparations

This causes malabsorption of iron

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A female patient with pneumonia has been administered doxycycline hydrochloride. This drug relates to the following group of antibiotics:

Aminoglycosides

Cephalosporins

Tetracyclines

Macrolides

Penicillins

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A pharmacy received the goods according to the accompanying documentation. Who is responsible for keeping the record of medicines received by a business entity?

Chief accountant

Materially responsible person

Authorized representative

Pharmacist of the pharmacy

Trustee

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Under the SPh of Ukraine, one of the reactions for the detection of calcium cation presence in drugs is the reaction with:

Hydroxyquinoline

Glyoxal-hydroxyanil

Sulfuric acid

Hydroxylamine

Alizarin

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A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:

Ursodeoxycholic acid

Citric acid

Gamma-aminobutyric acid

Acetylsalicylic acid

Mefenamic acid

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A patient with acute heart failure and cardiac glycoside intolerance was given an injection of dobutamine. What is the mechanism of its action?

Inhibition of phosphodiesterase

Stimulation of M-cholinergic receptors

Stimulation of в1-adrenoceptors

Stimulation of a1 -adrenoceptors

Block of K+-, Aa+-ATPase

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Which of the methods to fill ampoules with injectable solutions makes it possible to protect capillaries from contamination with thick and viscous solutions?

Squeezing-through

Syringe

Vapor condensation

Vacuum

Turbo vacuum

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When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the board members in a joint-stock company?

Limited to the double amount of deposits

Unlimited and solidary

Limited to the amount of deposits

Limited to the value of their shares

Limited to the contributions to the statutory fund and their property

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In order to verify the purity of the essential oil, some ethanol was added into the test tube with peppermint oil. The mixture became turbid. This means that the peppermint oil contains the following impurity:

Diethyl ether

Ethyl acetate

Fatty oil

Phenol

Acetone

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5 % solution of methylcellulose is used as a stabilizer for preparing a suspension of the following drug substance:

Starch

Terpine hydrate

Magnesium oxide

Bismuth nitrate basic

Zinc oxide

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An analytical chemist of the quality control department of a pharmaceutical plant can prove the presence of the cation in the test substance with a solution of potassium:

Chloride

Ferrocyanide (III)

Hydroxide

Pyroantimonate

Nitrate

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Magnesium peroxide identification is performed by the reaction of perchromic acid formation. What color is produced as a result of this reaction?

Yellow

Green

Blue

Black

Red

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A forensic medicine laboratory received some biological material. It was to be tested for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:

Ethanol acidified with oxalic acid

Chloroform

Water alkalized with ammonia solution

Water acidified with sulfuric acid

Propanol acidified with oxalic acid

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Pharmacies prepare injectable solutions. Which solution is prepared without any stabilizer?

Sodium bicarbonate solution

Novocaine solution

Solution of caffeine sodium benzoate

Glucose solution

Sodium thiosulfate solution

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Ammifurinum contains furocumari-nes. These biologically active substances are derived from:

Rhizomes and roots of angelica

Fruits of psoralea

Fruits of toothpick ammi

Fruits of large ammi

Fruits of common parsnip

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Quality of ampouled injection solutions is tested as to various parameters. How many ampullae are to be checked for assessing the quality of sealing (hermeticity)?

97 %

75 %

80 %

50 %

100%

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A pharmacy compounds suspensions. What substance can be used for preparing a suspension without adding the stabilizer?

Menthol

Sulfur

Phenyl salycylate

Magnesium oxide

Camphor

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All employees are entitled to annual leave. What is the duration of the additional leave for pharmacy employees with non-standard working hours?

Thirty calendar days

Ten calendar days

The additional leave is not granted

Seven calendar days

Twenty calendar days

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One of the packagings stored at the warehouse of finished products has a damaged label. It is known that the drug substance in this packaging relates to alkaloids. In course of group qualitative tests for alkaloids the drug substance reacted positively with murexide. Further identification of the drug substance should be limited to the following group of derivatives:

Purine

Isoquinoline

Indole

Quinoline

Tropane

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Industrial, labor and socioeconomic relations between the head of a pharmaceutical company and the employees are regulated by:

Statute

Contract

Employment agreement

Collective agreement

Corporate code

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A pharmacy received the following formulation: Rp.: Dibazoli 0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose:

0,27

0, 26

0, 30

0, 25

2, 7

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Xenobiotics are metabolized in the body. The main metabolite of the acetic acid is:

Methyl alcohol

Isopentyl alcohol

Acetaldehyde

Valeric acid

Formic acid

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Under the SPhU, the pharmacopei-al preparation 'Aether anaestheti-cus'is not allowed to have peroxide impurity. What reagent should be used to detect peroxides?

Solution of starch and potassium tetraiodomercurate

Solution of starch and potassium bromide

Lugol’s reagent

Grade reagent

Solution of starch and potassium iodide

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Arrangement of drugs in the retail space of a pharmacy can be characterized as either strong or weak. What arrangement of drugs is regarded as weak?

Cashier desk zone

On the lower shelves

The shelves on the right side as the buyers pass along

Zones with a good frontal look

At the intersection of the ranks of shelves

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When calculating the personal income tax, the tax social privilege is taken into account. Its rate depends on a certain statutory amount. Specify this amount:

Cost of living for incapacitated persons

Cost of living for one person

Cost of living for children aged 6 to 18 years

Minimum statutory wage

Maximum payroll fund

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Fatty oils containing unsaturated fatty acids are used for the prophylaxis of atherosclerosis. Specify the starting materials of herbal origin that contain fatty oil:

Psoralea fruits

Parsnip fruits

Ispaghula seed

Chestnut seed

Pumpkin seed

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The phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different starting materials. Specify the biogenic stimulators of animal origin:

Vitreous body, placental suspension for injections, plasmolum, solcoseryl

Liquid aloe extract, aloe liniment, aloe juice, biossedum

Liquid aloe extract, aloe liniment, plasmolum

Peloidinum, humisolum, torfotum, plasmolum, solcoseryl

Peloidinum, humisolum, torfotum, Fibs Rro injectionibus

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A pharmacy network received a batch of raw material without analysis protocol. It was identified as marshmallow root by the external charcteristics. The reaction with 5% alkali liquor was positive. This indi- cates the presence of:

Pectins

Gums

Slimes

Cellulose

Starch

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A pharmaceutical analyst tests anhydrous glucose for purity according to the requirements of the SPhU. Inadmissible barium impurity can be detected by using the following acid:

Hydrochloric

Sulphuric

Acetic

Nitric

Perchloric

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The chemical name 1-benzoyl-5-ethyl-5-phenyl-barbituric acid stands for the following substance relating to barbiturates:

Barbital

Phenobarbital

Benzobamil

Hexenal

Benzonal

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What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?

Securinine nitrate

Novopassit

Glaucine hydrochloride

Vinblastine

Ergotamine

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A pharmaceutist prepares 3000 mL of valerian root infusion for a hospital department. The given amount of extract should be infused in a water bath for:

45 minutes

25 minutes

10 minutes

15 minutes

30 minutes

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A pharmaceutist has prepared a solution of menthol oil. Specify the dissolution temperature of the active substance:

70-80 ° C

30-40 °C

20-30 °C

40-50° C

60-70 °C

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Forensic toxicological analysis of a mineralizate revealed copper. For the initial detection of copper ions the following substance is used:

Diphenylcarbazide

Diphenylamine

Sodium diethyldithiocarbamate

Dithizone

Plumbum diethyldithiocarbamate

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A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?

Ethyl mercury chloride

Hexachlorocyclohexane

Heptachlor

DDT

Dichlorvos

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As a result of condensation of substituted malonic esters and urea the derivatives of the following substance are obtained:

Pyridazine

Pyridine

Pyrimidine

Pyrazine

Pyrazole

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Which of the following ophthalmic dosage forms is produced only industrially?

Eye rinses

Eye drops

Ophthalmic ointments

Ophthalmic inserts

Eye washes

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What medication should be used as an antidote to eliminate the respiratory depression caused by an overdose of a narcotic analgesic?

Camphor

Aethimizolum

Naloxone

Cordiamine

Ammonia

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Fenofibrate relates to the following pharmacological group:

Hypnotics

Hypolipidemics

Antihypertensives

Fibrinolysis inhibitors

Indirect anticoagulants

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Which of the following vaginal dosage forms relate to the officinal formula, that is, are prepared in a pharmacy?

Vaginal capsules

Vaginal foams

Vaginal tablets for preparing solutions and suspensions

Pessaries

Vaginal tablets

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The glidants aerosil or magnesium stearate together with talc are added to the excipients in hard gelatin capsules in order to facilitate the following property:

Compactibility

Moisture regulation

Homogenity

Powder flowability

Homogeneous mixing

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A student has been prescribed a tonic. This may be the tincture of the following medicinal plant:

Purple foxglove

Black locust

Java tea (orthosiphon aristatus)

Common yarrow

Rhodiola rosea

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A 25-year-old female patient had been taking antibiotics for 7 days, the disease was complicated by the development of intestinal dysbiosis. This complication should be treated by the drugs of the following group:

Adaptogens

Antispasmodics

Probiotics

Antacids

Choleretics

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Which group of adjuvants includes polyvinyl alcohol used under the SPhU?

pH adjusters

Prolongators

Preservatives

Isotonizing agents

Antioxidants

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Which of the following drugs should be used for prevention of bronchial asthma attacks?

Diphenhydramine hydrochloride

Drotaverine

Cromolyn sodium

Salbutamol

Ambroxol

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A pharmaceutist has to prepare a medication by the following formulation: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place:

Sodium benzoate

Sugar syrup

Liquoris Ammonii anisatis

Mint water

Sodium hydrogen carbonate

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A pharmaceutist prepares an ointment under aseptic conditions on the sterile ointment base, namely the composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technique of ointment preparation is typical for the following substance:

Sodium sulfate

Sodium chloride

Benzylpenicillin sodium salt

Pilocarpine hydrochloride

Thiamine chloride

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Under the chemico-toxicological classification, toxic compounds are grouped according to the method of their isolation from the biological material. What compound can be isolated by steam distillation?

Analgene

Diazepam

Arsenicum

Chloral hydrate

Atropine

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Toxic medicines are isolated from biological material at a certain pH level of the medium. What substance is extracted from acidic aqueous extracts?

Cocaine

Atropine

Chlorpromazine

Caffeine

Morphine

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What drug is indicated in case of taking an overdose of depolarizing muscle relaxants?

Metoprolol

Unithiol

Neostigmine methylsulfate

Magnesium sulfate

Naloxone

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A 20-year-old female patient has been administered bicillin for rheumatic fever prophylaxis. Specify the frequency of bicillin-5 administration:

Once in 3 days

Once every 3 weeks

Once per week

Once per month

Once a day

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A 65-year-old male patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient takes dai- ly 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?

Hypersensitivity reaction

Food poisoning

Tachyphylaxis

Withdrawal syndrome

Glycoside intoxication

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Vincamine alkaloid reduces blood pressure, has a pronounced sedation effect, as well as hemostatic and anti-inflammatory effect. What herb is the source of this alkaloid?

Thick-fruited pagoda tree

Northern wolfsbane

Yellow water-lily

Common periwinkle

Bluish larkspur

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The galenical preparations workshop produces belladonna tincture. Specify the required ratio for this dosage form:

1:1

1:20

1:2

1:5

1:10

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Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:

Hydrogenated fat

Polyethylene oxide

Methyl cellulose

Silicon

Vaseline, lanolin

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A patient with acute heart failure has been administered an adrenomimetic agent. What drug is it?

Metoprolol

Salbutamol

Corglycon

Dobutamine

Digoxin

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Oil liniments are produced with fatty oils used as a base. What kind of oil should be used by a pharmacist if it was not specified in the formulation?

Cod-liver oil

Sunflower oil

Petrolatum

Eucalyptus oil

Sesame oil

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A pharmacy received a formula for an alcohol solution of methylene blue with unspecified alcohol concentration. In this case, a pharmacutist must use ethyl alcohol of the following concentration:

70 %

96 %

40 %

60%

90 %

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Production unit for ampouled medicinal preparations produces procaine hydrochloride solution. This solution is stabilized by adding:

1,5 g of amino-propylene glycol

0,1 mol/l of sodium hydroxide solution

0,1 mol/l of hydrochloric acid solution

0,1 mol/l of sodium hydrogen carbonate solution

20,0 of sodium hydrogen carbonate

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Recommend a drug for the treatment of tachyarrhythmia epi- sodes:

Caffeine sodium benzoate

Atropine

Propranolol

Adrenaline

Dobutamine

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A 35-year-old female customer came to a pharmacy to purchase a medicine for the prevention of influenza. Which of the following drugs can be recommended?

Lamivudine

Acyclovir

Rimantadine

Ganciclovir

Ribavirin

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Employees of a company can be instructed to go on a business trip by the orders of the company’s head. Specify the deadline for submission of an expense report after the employee’s return from the trip:

5 days

3 days

2 days

4 days

6 days

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A pharmaceutical analyst analyzes a dosage form containing zinc sulfate. What reagent enables him to confirm the presence of the zinc cation in the analyte?

Silver nitrate

Sodium sulfide

Sodium tetraphenylborate

Ammonium chloride

Potassium ferrocyanide

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Lily of the valley is widely regarded as a cardiac stimulant and sedative. During the raw material procurement, the following plant may occur in the harvested crop:

Viola tricolor

Treacle-mustard (Erysimum chei-ranthoides)

Viola arvensis

Spring adonis

Round-leaved pyrola

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A pharmaceutist prepares an infusion at a ratio of 1:30. What herbal raw material will be used?

Marshmallow root

Oak bark

Lily of the valley grass

Shoots of Marsh Labrador tea

Sage leaves

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A pharmaceutist has prepared vaginal suppositories. Specify the form of these suppositories:

Torpedo

Marbles

Cone

Cylinder

Sticks

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Under the SPhU (appendix 2), leaves of ginkgo are standardized by the content of:

Flavonoids

Coumarins

Alkaloids

Chromones

Saponins

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A clinical pharmaceutist invited to a medical conference made a report on the antiviral drug acyclovir. What is its mechanism of action?

It inhibits the synthesis of nucleic acids

It increases the permeability of the cell membrane

It antagonizes with PABA

It blocks the synthesis of the cell wall

It inhibits the synthesis of proteins

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What kind of marketing is provided in case of negative demand for goods and services, that is, in a situation when the demand is absent in a substantial part of the potential market?

Synchro marketing

Demarketing

Stimulating

Conversion

Remarketing

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Prescriptions for the controlled drugs dispensed under the reimbursement program (except for the narcotic and psychotropic preparations in substance) are issued on the following prescription form:

№3, single copy

№1 in duplicate

№1 and № 3

№1, single copy

№3 in duplicate

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In case of the planned closure of a pharmacy for repair works, technical re-equipment or other works, a business entity is obliged to give a written notice to the Territorial State Inspectorate for Quality Control of Medicines in advance, but not later than:

5 days in advance

3 days in advance

10 days in advance

7 days in advance

12 days in advance

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Pharmacy №7 is engaged in both sales and production. What operations ARE NOT REGISTERED in the journal of laboratory and prepacking works?

Packaging of finished products in certain amounts

Preparation of commercially available medications

Preparation of concentrated solutions

Extemporaneous compounding of dosage forms

Preparation of semi-finished products

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Specify a drug having an analeptic and psychostimulant effect:

Diazepam

Diclofenac sodium

Corglycon

Caffeine sodium benzoate

Neostigmine methylsulfate

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What medicines are used to eliminate bronchospasm?

в-blockers

M-cholinomimetics

в-adrenergic agonists

a-adrenergic agonists

Cholinesterase inhibitors

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Alkaloid glaucine has an antitussive effect that is stronger and longer if compared to that of codeine, and exhibits no narcotic side effects. What medicinal plant contains glauci-ne?

Celandine

Thermopsis lanceolata

Yellow hornpoppy

Henbane bell (Scopolia carniolica)

Datura

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Drug plant Dioscorea nipponi-ca is the starting materials for the production of Polysponinum drug which is used in the complex treatment of atherosclerosis. Specify the active compounds of dioscorea:

Steroid saponins

Triterpene saponins

Alkaloids

Essential oil

Cardiac glycosides

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A hypertensive patient had been administered a diuretic as a part of the combined therapy. The administered drug caused hypokalemia. Specify this drug:

Allopurinol

Amiloride

Hydrochlorothiazide

Triamterene

Spironolactone

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A pharmaceutical factory produces herbal juice from fresh raw material. What operation should be performed at the stage of juice purification?

Adsorption

Sedimentation

Crystallization

Heating followed by rapid cooling

Filtration

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Cash receipts and payments at a pharmacy are recorded in the cashbook. Which of the following cash transactions IS NOT REGARDED as a receipt transaction?

Recognizing cash receipts from sales at a pharmacy

Recognizing cash receipts from sales at pharmacy outlets and kiosks

Recognizing accrued salaries and advance payable

Return of unused disbursement funds

Issuing funds to be accounted for

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What system includes a set of legal rules that regulate the amounts, forms, methods and time limits for collecting taxes and tax-like charges that enable the state to perform its functions?

Remuneration of labor

Tax

Accounting

Reporting

Statistic

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Phytochemical workshop of a factory manufactures pancreatin. What is the starting material for obtaining pancreatin?

Gastric mucosa of pigs

Lungs of cattle

Pancreas of pigs or cattle

Heart of cattle

Egg white

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In case of simultaneous use of metronidazole and oral anticoagulants derived from coumarin patients must be warned about:

Potentiation of metronidazole effect

Higher neurotoxicity

Potentiation of anticoagulants effect and the risk of bleeding

Reduction of anticoagulants effect

Reduction of metronidazole effect

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Specify the principle of the pharmacy accounting which complies with the following definition: 'This principle provides for continuous following the adopted accounting policy. Any changes to the accounting policy must be well-grounded and fixed in the financial statements':

Expenses against revenues matching

Going concern

Consistency

Periodicity

Full disclosure

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At a maternity hospital a pregnant woman with weak uterine contractions has been administered oxytocin. This drug relates to the following pharmaceutical group:

Anabolic steroids

Thyroid hormone preparations

Mineral corticoids

Pituitary hormone preparations

Glucocorticoids

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What factor underlies the mechanism of the analgesic effect of morphine hydrochloride?

Inhibition of histamine receptors

Inhibition of phosphodiesterase

Stimulation of adenylate cyclase

Inhibition of cholinesterase

Stimulation of opiate receptors

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Analytical and control laboratory determines quality of fatty oils by using certain chemical indices. Specify the chemical index that is demonstrative of the fatty oil drying:

Saponification number

Peroxide number

Acid number

Iodine absorption number

Ester number

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The head of a pharmaceutical company 'Azalea'applies different types of control. The control which starts with logging in to the system of organization before commencement of work and is exercised through rules, procedures, etc. refers to:

Final control

Centralized control

Decentralized control

Current control

Preliminary control

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A 30-year-old male patient diagnosed with acute osteomyelitis has been administered an antibiotic that is highly effective in penetrating the bone tissue. What drug has been chosen?

Polymyxin-M

Ampicillin

Penicillin

Lincomycin

Bicillin 3

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A pharmaceutist dispensed doxycycline to a patient and recommended to abandon dairy products. What is the reason for such recommendation?

Disruption of digestion process

Dairy products are not digested

Deceleration of the antibiotic absorption

Increased risk of dysbiosis

Increase in the antibiotic toxicity

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Commercial and financial activity of a pharmacy involves using returnable tare. Which of the following containers are returned to the supplier?

Glassware

Glass-stoppered bottles

Packaging materials

Metal cylinders

Paper boxes

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A pharmacy has a set of documents which confirm the ownership of computer programs. Specify the balance sheet item that shows the pharmacy’s property:

Monetary assets

Goods

Stock

Low-value equipment

Intangible assets

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In order to expand its range of activities, pharmacy №12 purchased some manufacturing equipment. What group of economic resources does the manufacturing equipment relate to?

Goods

Incomplete capital investments

Tara

Fixed assets

Tangible assets

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A pharmaceutical analyst added solutions of zirconyl nitrate and alizarin to a drug substance. The reaction produced red color turning into yellow. Specify the analyte:

Sodium bromide

Sodium fluoride

Sodium thiosulfate

Sodium chloride

Sodium iodide

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A pharmaceutical company studies the market situation in terms of a relationship between supply and demand, price level, stock of goods, etc. What is the company’s actual object of study?

Market structure

Market infrastructure

Market scope

Market behaviour

Conditions for the market existence

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During a medical briefing a pharmacy intern was asked about the mechanism of antiatherosclerotic effect of clofibrate (fenofibrate). What is the correct answer?

It inhibits the release of free fatty acids from adipose tissue

It has an antioxidant effect

It binds bile acids in the small intestine

It lowers triglycerides

It inhibits the cholesterol absorption

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What style of behavior in conflict situations involves partial satisfaction of the interests of both parties by mutual concessions with due consideration of all pros and cons?

Dominance

Compromise

Cooperation

Competition

Evasion

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A pharmacy received a formulation for an extemporaneously compounded dosage form. The formula includes phenobarbital compounded with other drugs. Specify the required prescription form:

Form № 3

Form № 1

Form № 2

Form № 2 in duplicate

Form № 1 in duplicate

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A pharmacy has purchased a refrigerator and computer. These fixed assets are placed on the pharmacy’s balance sheet at the following value:

Liquidating

Market

Historic

Residual

Amortized

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Galenic preparations are produced with the use of various extractants. What extractants require pressure as a prior condition for the extraction process?

Methyl alcohol, acetone

Liquefied gases

Dichloroethane, chloroform

Ethanol

Vegetable oils

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In the production of dry extracts the drying of purified extracts may not involve condensation of the the liquid extractions. What equipment should be used in this case?

Shelf drier

Spray drier

Rotary one-flow drier

Thermostat

Vacuum oven

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Buckthorn bark is used as a laxative. Specify the period for procurement of raw material of alder buckthorn bark:

Winter

Autumn

Spring, during the circulation of sap

Frondescence

The period of full ripeness

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A pharmacy received a prescription for phenobarbital tablets written out by a physician of the city clinic to an epileptic patient. Prescripti- ons for this drug must be written out on the following prescription form:

Form № 1 in duplicate

Form № 2

Form № 1 in a single copy

Form № 3 in duplicate

Form № 3 and № 1 in a single copy

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A pharmaceutical analyst has to test the substance of iron sulfate heptahydrate for purity. What reagent should be used to detect zinc cation in the substance?

Silver nitrate

Ammonium oxalate

Barium chloride

Sodium tetraphenylborate

Potassium ferrocyanide

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A pharmaceutical analyst performs the identification of phthalylsulphathiazole (phthalazol). In compliance with the SPhU requirements, the substance is to be heated with resorcinol in the presence of sulfuric acid. The subsequent addition of sodium hydroxide and water results in:

Abundant white precipitate

Extensive yellow precipitate

Red-violet color

Intensive blue color

Intensive green fluorescence

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Under the SPhU, presence of ammonium salts in sodium tetraborate can be detected by method A by using a solution of the following substance:

Potassium ferrocyanide

Sodium tetraphenylborate

Silver nitrate

Barium chloride

Alkaline potassium tetrai-odomercurate

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A pharmaceutical analyst performs the identification test of lidocaine hydrochloride under the SPhU. The identity is determined by the melting point of precipitate which is produced as a result of reaction with a solution of the following acid:

Thioglycolic

Acetic

Citric

Picric

Phosphoric

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A pharmaceutist with 10 years of service legth is on a sick leave due to temporary disability. What allowance is he entitled to?

100% of the average wage

70 % of the average wage

40 % of the average wage

60 % of the average wage

80 % of the average wage

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Pharmacy cashier is responsible for recording all credit and debit transactions. To enter into the books the cash received, a cashier should issue:

Goods delivery note

Cash payment voucher

Cash receipt voucher

Goods receipt note

Receipt note

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Organizational form of business in which a company does not produce goods or services itself but owns other companies’ controlling stake and thereby supervises their activity is called:

Holding

Cartel

Trust

Syndicate

Conglomerate

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The head of a wholesale pharmaceutical company applies modern theories in order to effectively motivate sales staff and determine the amount of remuneration. Specify one of the groups of motivation theories:

Primary

Process

Structural

System

Secondary

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Which of these drugs kept in the pharmacy stock relates to the group of laxatives?

Atropine

Morphine

Vicasol

Bisacodyl

Heparin

‹ Назад

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A pharmacy received a batch of chemotherapeutic agents. Select an antiviral drug:

Isoniazid

Acyclovir

Doxycycline

Benzylpenicillin sodium salt

Rifampicin

‹ Назад

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A 40-year-old patient has a history of bronchial asthma and heart rhythm disorders in form of bradyarrhythmia. Bronchospasm can be eliminated by the drugs of the following pharmacological group:

в-blockers

M-cholinomimetics

Cholinesterase inhibitors

Muscle relaxants

M-cholinergic antagonists

‹ Назад

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