Step 2 - Pharmacy 2014

A sample of biological material contains mercury. Specify the method of mercury isolation:

Isolation by acidified alcohol

Steam distillation

Isolation by organic solvents

Mineralization

Destruction

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A pharmaceutist has to prepare an oil emulsion with menthol. Specify the appropriate way of the active substance incorporation:

Incorporation into the ready primary emulsion

Dissolution in oil

Dissolution in water intended for diluting the primary emulsion

Dispersion with the addition of ready emulsion

Dissolution in the ready emulsion by heating

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It is required to prepare a decoction of bearberry leaves. Specify the ratio of raw materials to the extractant if not indicated in the formulation:

1:400

1:20

1:30

1:10

1:5

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A pharmaceutist prepared an injectable solution of novocaine. What stabilizer had been used?

Sodium sulfite solution

Sodium thiosulfate solution

Sodium bicarbonate solution

Stabilizator of Weibel

Hydrochloric acid solution

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A disabled veteran of the WW2 has been prescribed codeine powder. What is the maximum permissible amount of codeine that can be dispensed by the prescription?

0, 1

1, 0

0, 6

1, 2

0,2

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Certain groups of drugs are subject to strict record keeping and storage in pharmacies. Specify a drug that relates to the group of narcotics:

Ethylmorphine hydrochloride

Dicaine

Clonidine

Dephedrinum

Analgene

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Under the analytical normative documents, atropine sulfate should be titrated with hydrochloric acid solution in the anhydrous acetic acid medium in the presence of the following indicator:

Methylene blue

Methyl orange

Phenolphtalein

Crystal violet

Thymol blue

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Losartan as a part of treatment of arterial hypertension is contraindicated in case of:

Hyperglycemia

Hyperlipidemia

Hypokalemia

Urine acid diathesis

Pregnancy

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Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?

Ticlopidine

Phenylinum

Acetylsalicylic acid

Streptokinase

Heparin

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At the end of the dug action drug addicts develop severe mental, neurological and somatic disorders. This complex of symptoms is called:

Tachyphylaxis

Withdrawal syndrome

Cumulation

Sensibilization

Tolerance

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Patients with heart failure caused by persisting cardiac and coronary vessel dysfunction can be recommended preparations produced from the following herbal raw material:

Ginseng roots

Hawthorn fruits

Calendula flowers

Barberry roots

Aralia roots

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Rutin exhibits P-vitamin activity. What medicinal plant is used as starting materials for the industrial production of rutin?

Fructus Hippophaes rhamnoides

Herba Bidentis tripartitae

Herba Polygoni avicularis

Flores Helichrysi arenarii

Fructus Sophorae japonicae

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A patient came to a pharmacy to purchase cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?

Folium Uvae ursi

Herba Achilleae millefolii

Rizoma et radix Sanquisorbae officinalis

Rizoma Calami

Radix Taraxaci officinalis

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Pharmaceutical warehouse received a batch of herbal raw material of cinnamon rose. Under the State Pharmacopoeia, it is required to test this raw material for the following active substances:

Flavonoids

Tannins

Anthracene derivatives

Ascorbic acid

Essential oil

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Under the analytical normative documents, prior to direct bromatometric determination of arsenous acid anhydride the following substance should be added to the analyzed solution:

Sodium hydroxide

Potassium bromide

Sodium chloride

Potassium nitrate

Sodium thiosulfate

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A pharmaceutical analyst of an analytical laboratory performs quantitative determination of silver nitrate by thiocyanatometry. What indicator is used in this case?

Phenolphtalein

Sodium eosinate

Potassium chromate

Iron (III) ammonium sulphate

Starch

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A pharmaceutical company produces concentrated extracts. Specify the concentration of ethanol in the extractant required for the production:

70-90 %

20-40%

50-60 %

90-96 %

70-75 %

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A factory workshop producing suspensions and emulsions is going to start manufacturing new drugs. What equipment can be used for the ultrasound processing of drugs?

Centrifugal mixer with rotating housing

Rotor-pulsation apparatus, di-smembrator

Disintegrator, liquid whistle

Dismembrator, electrical impulse plasmolyzer

Liquid whistle, magnetostrictive source

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The ointment workshop of a pharmaceutical plant launches production of a new ointment. Specify the manufacturing operation that ensures equal distribution of the drug substance in the base:

Packaging

Pre-packing

Homogenization

Standardization

Preparation of the base

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The aerosol workshop of a pharmaceutical plant uses various groups of propellants in the production. What propellants relate to the group of volatile organic solvents?

Methylene chloride, ethylene chloride

Vinyl and methyl chloride

Propane, butane, isobutane

Freon (CFCs)

Carbon dioxide

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The phytochemical workshop of a pharmaceutical plant manufactures liquid extracts. How many volume parts of the liquid extract can be produced from one weight part of herbal raw material in compliamce with the State Pharmacopoeia?

5 parts

0,5 part

1 part

10 parts

3 parts

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An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?

Bromatometry

Mercurimetric determination

Iodometry

Nitritometric determination

Chelatometry

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A chemist of the production unit for ampouled medicinal preparations analyzes injectable solution of calcium chloride. According to the requirements, the analyzed solution should be colorless. To meet this requirement, the analyte should be compared to:

Chloroform

Water

Hydrochloric acid

Acetone

Alcohol

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What drug is used as the specific antidote in case of intoxication with iron preparations?

Bemegride

Penicillamine

Atropine

Deferoxamine

Protamine sulfate

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Specify the type of capsules which are used for dispensing camphor powders:

Paraffin

Common paper

Cellophane

Parchment

Waxed

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A pharmacy received a formulation for an extemporaneously compounded medication. Specify the document that is used to set the price for such medication:

Inventory report

Cash receipt voucher

Certificate of analysis

Retail price list for drugs

Certificate of quality

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A pharmaceutist has prepared a suspension ointment. Specify the substance used for this type of ointments:

Menthol

Zinc oxide

Protargolum

Ichthyol

Potassium iodide

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Ergot (Secale cornutum) is used as an uterotonic agent in obstetric practice and for the treatmet of cardiovascular diseases. The authenticity of the raw materials is proved by the content of:

Ergotoxine

Atropine

Reserpine

Ajmaline

Hyoscyamine

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Among the given principles of market segmentation select a principle that is used in the study of drug market most often:

Socio-economic

Psychological

Psychographic

Behavioral

Demographic

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Personnel records refer to the following type of documents:

Pharmaceutical

Reference information

Directive

Scientific

Managerial

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A pharmacy received a formulation for eye drops containing 1% solution of pilocarpine hydrochloride. What substance should be used to ensure that the resultant solution is isotonic?

Sodium sulfate

Sodium nitrate

Glucose

Sodium chloride

Boric acid

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A pharmaceutist prepared 10 powders containing atropine sulfate in an amount of 0,00005 per dose. What trituration had been used?

1:20

1:50

1:1000

1:10

1:100

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Which of the following antihypertensive drugs has potassiumsparing effect?

Diltiazem

Metoprolol

Prazosin

Triamterene

Furosemide

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Immunochemical test for detection of opiates in urine is carried out on polystyrene plates with the use of horseradish peroxidase as a label. This method is classified as:

Homogeneous immunofluorescence

Heterogeneous immunoassay

Heterogeneous radioimmunoassay

Heterogeneous immunofluorescence

Homogeneous immunoassay

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When developing the system of marketing communications, a company should consider the characteristics of each tool used for market promotion of a drug. Which of the following characteristics is typical for advertising?

Depersonalization (non-personal communication)

Non-mass communication

There is no correct answer

All answers are correct

Two-way communication

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Quantitative determination of pyridine derivatives is performed by acidimetry in nonaqueous medium. What titrant is used for this purpose?

Sodium hydroxide

Nitric acid

Sodium thiosulfate

Sulfuric acid

Perchlorate acid

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What antiprotozoal agent can be recommended to a female patient with trichomoniasis?

Primaquine

Metronidazole

Solusurminum

Chloridinum

Chiniofonum

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A patient has a history of chronic bronchitis. Recommend him an expectorant which can be purchased at a pharmacy to facilitate the expectoration of thick and viscous mucus:

Falimint

Salbutamol

Ambroxol

Libexin

Glauvent

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What drug from the group of cardiac glycosides can be used as an alternative for strophanthine if it is not available at a pharmacy?

Isolanidum

Adonisidum

Celanidum

Digitoxin

Corglycon

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A pharmacy received the following formulation: Rp.: Xeroformii Picis Liquidae Betulae Olei Ricini 100,0 M.D.S. For wound anointing. Specify the dosage form:

Liniment

Hydrophilic ointment

Combined ointment

Solution

Paste

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What is the most common symptom of atropine intoxication?

Mydriatic pupils with no light response

Myotic pupils with no light response

Bradycardia

Hyperhidrosis

Reduction of intraocular pressure

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In order to detect the presence of thiosulfate ions a pharmaceutical analyst added the excess reagent. The resulting reaction produced a white precipitate which was slowly turning yellow, then brown, and black. What solution was added?

Silver nitrate

Diphenylamine

Barium chloride

Lead (II) acetate

Ammonium oxalate

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Quantitative analysis of boric acid can be performed by alkalimetric titration in the presence of:

Ammonia buffer

Ethyl alcohol

Mannitol

Mercury (II) acetate

Nitric acid

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A customer came to a pharmacy and presented the prescription for Tramadol tablets. For how long such a prescription must be kept at a pharmacy?

10 years, exclusive of the current year naЕ.01 month, exclusive of the current year

6 months, exclusive of the current year

1 year, exclusive of the current year

5 years, exclusive of the current year

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A 6-year-old child with pneumonia had been administered an antibiotic. After treatment the child lost the hearing. What group of antibiotics might have caused this complication?

Aminoglycosides

Natural penicillins

Macrolides

Cephalosporins

Semi-synthetic penicillins

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Suppositories are prepared by various methods such as rolling, pouring, pressing. What base is used in the pouring method?

Paraffin

Cocoa butter

Coriander oil

Butyrolum

Vaseline

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Select the optimal antibacterial drug for the treatment of mycoplasma pneumonia:

Penicillin

Ampicillin

Rovamycin

Amoxiclav

Gentamicin

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Quantitative determination of pesticides in organic extracts after the isolation from the biological material can be done by various methods. What method of quantitative analysis of chlorophos is based on measuring the peak height parameter?

Biochemical method

Argentometry

Photometry

Thin-layer chromatography

Gas-liquid chromatography

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An analytical chemist of the quality control department of a pharmaceutical plant has to determine the average weight of glibenclami-de tablets. How many tablets should be tested for this purpose?

20

50

5

10

30

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A pharmacy received 10 kg of hawthorn tincture which was packaged in 80 ml bottles. This operation should be recorded in the following document:

Cashbook

Consolidated register

Formulation journal

Receipt for the ordered medication

Journal of laboratory and prepacking operations

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Employees of a pharmacy receive hourly rate wage and bonuses based on individual performance. What document is issued when calculating the payroll advance?

Cash receipt voucher

Invoice

Cash payment voucher

Inventory report

Payroll record

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Help a medical student to select an adrenergic drug for the treatment of anaphylactic shock:

Isadrinum

Fenoterolum

Galazolin

Clonidine

Epinephrine hydrochloride

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A 5-year-old child had accidentally drunk a bottle of eye drops. After 30 minutes the child developed shortness of breath, difficult swallowing, voice hoarseness, dilated pupils, hyperthermia. Which of the drugs might have induced the described manifestations?

Pilocarpine

Atropine

Adrenaline

Mesatonum

Novocaine

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A patient purchased peppermint leaves at a pharmacy. What recommendations on infusing this herbal raw material must be given by the pharmaceutist?

The infusion is to be prepared on an open fire

The infusion is to be prepared in a tightly closed vessel

The infusion is to be prepared at room temperature

The extract is to be artificially cooled 15 minutes after infusing

The extract is to be immediately filtered after infusing

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It is required to prepare 50 g of zinc ointment for a patient. What amount of zinc and vaseline must be weighed out by a pharmaceutist?

1,0 and 49,0 g

0,5 and 49,5 g

2,5 and 40,0 g

5,0 and 45,0 g

10,0 and 40,0 g

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Sterilization methods applied for the preparation of drugs under aseptic conditions can be differentiated into physical, mechanical, and chemical ones. Specify the chemical method of sterilization:

Dry heat sterilization

Addition of preservatives

UV light sterilization

Pressure steam sterilization

Radiation sterilization

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A patient had been given an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient developed red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucosa. What is the cause of this complication?

Tachyphylaxis

Immediate allergy

Local irritation

Delayed allergy

Withdrawal syndrome

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What is the mechanism of action of diclofenac sodium?

It activates adenylate cyclase

It blocks cyclooxygenase

It inhibits phosphodiesterase

It activates the synthesis of phosphodiesterase

It inhibits cholinesterase

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In order to identify deoxycorticosterone acetate a pharmaceutical analyst performed a steroid cycle reaction which produced cherry-red color and green fluorescence. What reagent was added?

Chloroform

Potassium hydroxide solution

Iodine solution

Concentrated sulfuric acid

Iron (III) chloride solution

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When investigating the case of drug intoxication, the expert commission should find out, whether intoxication had been caused by opium or omnopon. For this purpose it is required to conduct an addititional test for:

Papaverine

Codeine

Meconic acid and meconin

Thebaine

Morphine

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Within an accounting period a pharmacy has been providing the population with the finished medications. What business transaction will have an effect on increasing inventory of the pharmacy?

Salary accounting

Markdown according to the prepacking journal

Arrivals from the pharmaceutical warehouse

Write-off of low-value inventory

Write-off of goods

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Which of the following nonsteroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?

Nimesulide

Diclofenac

Acetylsalicylic acid

Indomethacin

Piroxicam

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A manufacturing enterprise plans to retail a new drug through the corporate network of pharmacies. What strategy of drug distribution will be used?

Flexible

Direct

Horizontal integration

Vertical integration

Multi-echelon

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When preparing an ointment with castor oil and vaseline a pharmaceutist failed to obtain a homogeneous system. What is the most likely cause of incompatibility between these components?

Immiscibility of the ingredients

Coagulation

Release of water of crystallization

Adsorption

Limited solubility

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In order to identify the toxic substance which was extracted from the acidic aqueous extract by an organic solvent, a toxicologist performed a murexide test which resulted in development of pink coloration. This indicates presence of the following substance in the sample:

Barbamyl

Morphine

Strychnine

Cocaine

Atropine

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Woolly foxglove is used as raw material for the production of the following drug:

Digitoxin

Corglycon

Erysimosidum

Lantosidum

Adonizid

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A 60-year-old female patient has a history of essential hypertension (stage II), ischemic heart disease, bronchial asthma. After the correction of pharmacotherapy, a patient experienced an attack of bronchospasm, and an escalation of dyspnea. What drug had caused the complication?

Aminophylline

Propranolol

Mucaltinum

Nifedipine

Salbutamol

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A pharmaceutical analyst with a 6-year length of service is on a sick leave due to temporary disability. He is entitled to the sickness allowance in the amount of:

80% of average wage

30 % of average wage

50 % of average wage

100 % of average wage

70 % of average wage

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Sage leaves procured for the production of essential oil should be dried at a temperature of:

100 °C

25-30° C

70-80 °C

50-60 °C

60-70 °C

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Which of the following antibiotics can be identified by means of the maltol formation test?

Streptomycin sulfate

Kanamycin monosulfate

Amoxicillin

Lincomycin hydrochloride

Doxycycline hydrochloride

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What is the main mechanism of action that underlies the bactericidal effect of penicillin on the coccal flora?

Activation of the immune system of the macroorganism

Disruption of synthesis of the microbial cell wall

Inhibition of protein synthesis

Phagocytic activity of leukocytes

Damage to the cytoplasmic membrane permeability

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What is the drug of choice for the treatment of acute pyelonephritis in a pregnant woman in the I trimester?

Biseptolum

Gentamicin

Norfloxacin

Amoxicillin

Chloramphenicol

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What is the most suitable drug that can be recommended for the treatment of rhinitis accompanying an ARVI in a 7-month-old child?

Naphthyzin

Boromentol ointment

0,9% warm water solution of NaCl

Pinosol

Galazolin

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What drug may cause the development of constipation in patients undergoing combined therapy for arterial hypertension?

Acetylsalicylic acid in small doses

Trimetazidine

Verapamil

Furosemide

Pananginum

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In a pharmaceutical company both American and Japanese management styles are used. Select a characteristic feature of the Japanese management style:

Fast evaluation and career advancement

Collective responsibility

Short-term employment

Individual decision-making process

Clearly formalized management structure

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Drug A is in the stage of market saturation. In order to push up intensive sales, management of the manufacturing company decided to use the following type of advertising:

Sales promotion

Personal sales

Informational

Aggressive

Public relations

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A person got poisoned with alcohols. What alcohol derivatives are used for the analysis by the method of gas-liquid chromatography?

Alkyl sulfates

Alkyl sulfites

Alkyl acetates

Alkyl nitrates

Alkyl nitrites

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A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the analyte?

Iron (III) chloride

Tartaric acid

Zinc oxide

Potassium permanganate

Sodium hydroxide

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A pharmaceutical analyst tests potassium bromide for magnesium and alkaline earth metals impurity. What solution is used for this purpose?

Sodium edetate

Silver nitrate

Potassium permanganate

Sodium nitrite

Hydrochloric acid

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A patient with a history of essential hypertension has been administered lisinopril. What is the mechani- sm of action of this drug?

It inhibits M-cholinergic receptors

It stimulates beta-adrenergic receptors

It inhibits alpha-adrenergic receptors

It inhibits ACE

It inhibits beta-adrenergic receptors

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A male patient has been administered an antiulcerant that blocks histamine receptors of the gastric mucosa. What drug is it?

Almagelum

Famotidine

Pirenzepine

Atropine sulfate

Omeprazole

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Stimulation of beta-cells of the pancreas causes the hypoglycemic effect of the following drug:

Heparin

Adrenaline hydrochloride

Prednisolone

Retabolilum

Glibenclamide

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A pharmaceutist prepared an ointment by the following formulation: Rp.: Tannini 0,2 Lanolini 3,0 Vaselini 10,0 M. utf. ung.

Trituration with liquid petrolate in a mortar by Deryagin rule

Dissolution in molten vaseline

S. To anoint the affected skin areas. What method of tannin incorporation was used?

Trituration with an alcohol in a mortar, blending with the base F. Dissolution in liquid petrolate

Water dissolution, emulsification with anhydrous lanolin

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Business transactions are displayed in the accounts. The entry in the account ledger that is made to record the incoming of economic resources is called:

Assets

Liabilities

Credit

Debit

Equity

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Within the matrix of Boston Consulting Group, a certain drug refers to a group of products called 'milking cash cows'. Specify the stage of the lifecycle of this drug:

Maturity

Growth

Withdrawal

Introduction

Decline

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An analytical laboratory has been commissioned to prove the presence of ethylenediamine in aminophylli-ne. Which of the following reagents makes it possible to detect ethylenedi-amine?

Sodium hydroxide

Copper (II) sulfate

Silver nitrate

Concentrated sulfuric acid

Barium chloride

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A patient has glaucoma. Recommend him a drug of the M-cholinomimetic group:

Ephedrine hydrochloride

Pylocarpine hydrochloride

Laevomycetin

Atropine sulfate

Sulfacyl sodium

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Advise an internship doctor on why iron preparations should not be administered together with antacids:

This prevents deposition of iron in the body

This causes increased binding to blood proteins

This causes malabsorption of iron

This increases intoxication with iron preparations

This accelerates elimination of iron preparations

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A female patient with pneumonia has been administered doxycycline hydrochloride. This drug relates to the following group of antibiotics:

Tetracyclines

Aminoglycosides

Cephalosporins

Penicillins

Macrolides

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A pharmacy received the goods according to the accompanying documentation. Who is responsible for keeping the record of medicines received by a business entity?

Chief accountant

Pharmacist of the pharmacy

Materially responsible person

Trustee

Authorized representative

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Under the SPh of Ukraine, one of the reactions for the detection of calcium cation presence in drugs is the reaction with:

Glyoxal-hydroxyanil

Hydroxyquinoline

Hydroxylamine

Alizarin

Sulfuric acid

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A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:

Gamma-aminobutyric acid

Acetylsalicylic acid

Mefenamic acid

Ursodeoxycholic acid

Citric acid

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A patient with acute heart failure and cardiac glycoside intolerance was given an injection of dobutamine. What is the mechanism of its action?

Stimulation of a1 -adrenoceptors

Stimulation of в1-adrenoceptors

Block of K+-, Aa+-ATPase

Stimulation of M-cholinergic receptors

Inhibition of phosphodiesterase

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Which of the methods to fill ampoules with injectable solutions makes it possible to protect capillaries from contamination with thick and viscous solutions?

Squeezing-through

Vapor condensation

Syringe

Turbo vacuum

Vacuum

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When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the board members in a joint-stock company?

Limited to the contributions to the statutory fund and their property

Limited to the double amount of deposits

Unlimited and solidary

Limited to the amount of deposits

Limited to the value of their shares

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In order to verify the purity of the essential oil, some ethanol was added into the test tube with peppermint oil. The mixture became turbid. This means that the peppermint oil contains the following impurity:

Ethyl acetate

Phenol

Acetone

Fatty oil

Diethyl ether

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5 % solution of methylcellulose is used as a stabilizer for preparing a suspension of the following drug substance:

Terpine hydrate

Bismuth nitrate basic

Magnesium oxide

Zinc oxide

Starch

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An analytical chemist of the quality control department of a pharmaceutical plant can prove the presence of the cation in the test substance with a solution of potassium:

Pyroantimonate

Chloride

Ferrocyanide (III)

Hydroxide

Nitrate

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Magnesium peroxide identification is performed by the reaction of perchromic acid formation. What color is produced as a result of this reaction?

Black

Yellow

Green

Blue

Red

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A forensic medicine laboratory received some biological material. It was to be tested for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:

Water alkalized with ammonia solution

Propanol acidified with oxalic acid

Water acidified with sulfuric acid

Ethanol acidified with oxalic acid

Chloroform

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Pharmacies prepare injectable solutions. Which solution is prepared without any stabilizer?

Solution of caffeine sodium benzoate

Novocaine solution

Sodium thiosulfate solution

Sodium bicarbonate solution

Glucose solution

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Ammifurinum contains furocumari-nes. These biologically active substances are derived from:

Fruits of common parsnip

Fruits of toothpick ammi

Rhizomes and roots of angelica

Fruits of psoralea

Fruits of large ammi

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Quality of ampouled injection solutions is tested as to various parameters. How many ampullae are to be checked for assessing the quality of sealing (hermeticity)?

50 %

80 %

75 %

97 %

100%

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A pharmacy compounds suspensions. What substance can be used for preparing a suspension without adding the stabilizer?

Phenyl salycylate

Menthol

Sulfur

Magnesium oxide

Camphor

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All employees are entitled to annual leave. What is the duration of the additional leave for pharmacy employees with non-standard working hours?

The additional leave is not granted

Twenty calendar days

Ten calendar days

Thirty calendar days

Seven calendar days

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One of the packagings stored at the warehouse of finished products has a damaged label. It is known that the drug substance in this packaging relates to alkaloids. In course of group qualitative tests for alkaloids the drug substance reacted positively with murexide. Further identification of the drug substance should be limited to the following group of derivatives:

Quinoline

Purine

Indole

Isoquinoline

Tropane

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Industrial, labor and socioeconomic relations between the head of a pharmaceutical company and the employees are regulated by:

Statute

Collective agreement

Contract

Corporate code

Employment agreement

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A pharmacy received the following formulation: Rp.: Dibazoli 0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose:

0, 30

2, 7

0,27

0, 26

0, 25

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Xenobiotics are metabolized in the body. The main metabolite of the acetic acid is:

Isopentyl alcohol

Formic acid

Acetaldehyde

Methyl alcohol

Valeric acid

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Under the SPhU, the pharmacopei-al preparation 'Aether anaestheti-cus'is not allowed to have peroxide impurity. What reagent should be used to detect peroxides?

Solution of starch and potassium tetraiodomercurate

Solution of starch and potassium iodide

Solution of starch and potassium bromide

Lugol’s reagent

Grade reagent

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Arrangement of drugs in the retail space of a pharmacy can be characterized as either strong or weak. What arrangement of drugs is regarded as weak?

Cashier desk zone

Zones with a good frontal look

At the intersection of the ranks of shelves

On the lower shelves

The shelves on the right side as the buyers pass along

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When calculating the personal income tax, the tax social privilege is taken into account. Its rate depends on a certain statutory amount. Specify this amount:

Minimum statutory wage

Cost of living for incapacitated persons

Cost of living for one person

Maximum payroll fund

Cost of living for children aged 6 to 18 years

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Fatty oils containing unsaturated fatty acids are used for the prophylaxis of atherosclerosis. Specify the starting materials of herbal origin that contain fatty oil:

Ispaghula seed

Pumpkin seed

Chestnut seed

Psoralea fruits

Parsnip fruits

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The phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different starting materials. Specify the biogenic stimulators of animal origin:

Peloidinum, humisolum, torfotum, Fibs Rro injectionibus

Liquid aloe extract, aloe liniment, aloe juice, biossedum

Vitreous body, placental suspension for injections, plasmolum, solcoseryl

Liquid aloe extract, aloe liniment, plasmolum

Peloidinum, humisolum, torfotum, plasmolum, solcoseryl

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A pharmacy network received a batch of raw material without analysis protocol. It was identified as marshmallow root by the external charcteristics. The reaction with 5% alkali liquor was positive. This indi- cates the presence of:

Starch

Cellulose

Slimes

Gums

Pectins

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A pharmaceutical analyst tests anhydrous glucose for purity according to the requirements of the SPhU. Inadmissible barium impurity can be detected by using the following acid:

Sulphuric

Perchloric

Nitric

Hydrochloric

Acetic

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The chemical name 1-benzoyl-5-ethyl-5-phenyl-barbituric acid stands for the following substance relating to barbiturates:

Phenobarbital

Benzobamil

Barbital

Benzonal

Hexenal

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What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?

Glaucine hydrochloride

Vinblastine

Securinine nitrate

Ergotamine

Novopassit

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A pharmaceutist prepares 3000 mL of valerian root infusion for a hospital department. The given amount of extract should be infused in a water bath for:

25 minutes

10 minutes

45 minutes

15 minutes

30 minutes

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A pharmaceutist has prepared a solution of menthol oil. Specify the dissolution temperature of the active substance:

30-40 °C

40-50° C

70-80 ° C

20-30 °C

60-70 °C

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Forensic toxicological analysis of a mineralizate revealed copper. For the initial detection of copper ions the following substance is used:

Diphenylamine

Sodium diethyldithiocarbamate

Plumbum diethyldithiocarbamate

Dithizone

Diphenylcarbazide

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A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?

Hexachlorocyclohexane

DDT

Dichlorvos

Ethyl mercury chloride

Heptachlor

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As a result of condensation of substituted malonic esters and urea the derivatives of the following substance are obtained:

Pyridine

Pyrazole

Pyrimidine

Pyrazine

Pyridazine

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Which of the following ophthalmic dosage forms is produced only industrially?

Ophthalmic ointments

Eye drops

Eye washes

Eye rinses

Ophthalmic inserts

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What medication should be used as an antidote to eliminate the respiratory depression caused by an overdose of a narcotic analgesic?

Camphor

Aethimizolum

Naloxone

Cordiamine

Ammonia

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Fenofibrate relates to the following pharmacological group:

Hypolipidemics

Antihypertensives

Indirect anticoagulants

Fibrinolysis inhibitors

Hypnotics

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Which of the following vaginal dosage forms relate to the officinal formula, that is, are prepared in a pharmacy?

Pessaries

Vaginal tablets for preparing solutions and suspensions

Vaginal capsules

Vaginal foams

Vaginal tablets

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The glidants aerosil or magnesium stearate together with talc are added to the excipients in hard gelatin capsules in order to facilitate the following property:

Compactibility

Moisture regulation

Homogeneous mixing

Powder flowability

Homogenity

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A student has been prescribed a tonic. This may be the tincture of the following medicinal plant:

Java tea (orthosiphon aristatus)

Purple foxglove

Common yarrow

Black locust

Rhodiola rosea

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A 25-year-old female patient had been taking antibiotics for 7 days, the disease was complicated by the development of intestinal dysbiosis. This complication should be treated by the drugs of the following group:

Probiotics

Choleretics

Adaptogens

Antispasmodics

Antacids

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Which group of adjuvants includes polyvinyl alcohol used under the SPhU?

Preservatives

Antioxidants

pH adjusters

Prolongators

Isotonizing agents

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Which of the following drugs should be used for prevention of bronchial asthma attacks?

Diphenhydramine hydrochloride

Cromolyn sodium

Drotaverine

Ambroxol

Salbutamol

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A pharmaceutist has to prepare a medication by the following formulation: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place:

Sodium benzoate

Liquoris Ammonii anisatis

Sodium hydrogen carbonate

Mint water

Sugar syrup

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A pharmaceutist prepares an ointment under aseptic conditions on the sterile ointment base, namely the composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technique of ointment preparation is typical for the following substance:

Sodium sulfate

Benzylpenicillin sodium salt

Thiamine chloride

Sodium chloride

Pilocarpine hydrochloride

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Under the chemico-toxicological classification, toxic compounds are grouped according to the method of their isolation from the biological material. What compound can be isolated by steam distillation?

Arsenicum

Chloral hydrate

Atropine

Analgene

Diazepam

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Toxic medicines are isolated from biological material at a certain pH level of the medium. What substance is extracted from acidic aqueous extracts?

Cocaine

Chlorpromazine

Caffeine

Atropine

Morphine

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What drug is indicated in case of taking an overdose of depolarizing muscle relaxants?

Magnesium sulfate

Unithiol

Metoprolol

Neostigmine methylsulfate

Naloxone

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A 20-year-old female patient has been administered bicillin for rheumatic fever prophylaxis. Specify the frequency of bicillin-5 administration:

Once per month

Once per week

Once every 3 weeks

Once in 3 days

Once a day

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A 65-year-old male patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient takes dai- ly 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?

Hypersensitivity reaction

Tachyphylaxis

Withdrawal syndrome

Glycoside intoxication

Food poisoning

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Vincamine alkaloid reduces blood pressure, has a pronounced sedation effect, as well as hemostatic and anti-inflammatory effect. What herb is the source of this alkaloid?

Common periwinkle

Thick-fruited pagoda tree

Yellow water-lily

Bluish larkspur

Northern wolfsbane

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The galenical preparations workshop produces belladonna tincture. Specify the required ratio for this dosage form:

1:2

1:1

1:5

1:20

1:10

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Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:

Polyethylene oxide

Methyl cellulose

Vaseline, lanolin

Silicon

Hydrogenated fat

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A patient with acute heart failure has been administered an adrenomimetic agent. What drug is it?

Metoprolol

Digoxin

Dobutamine

Corglycon

Salbutamol

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Oil liniments are produced with fatty oils used as a base. What kind of oil should be used by a pharmacist if it was not specified in the formulation?

Petrolatum

Sunflower oil

Eucalyptus oil

Cod-liver oil

Sesame oil

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A pharmacy received a formula for an alcohol solution of methylene blue with unspecified alcohol concentration. In this case, a pharmacutist must use ethyl alcohol of the following concentration:

60%

70 %

90 %

96 %

40 %

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Production unit for ampouled medicinal preparations produces procaine hydrochloride solution. This solution is stabilized by adding:

0,1 mol/l of sodium hydroxide solution

20,0 of sodium hydrogen carbonate

0,1 mol/l of sodium hydrogen carbonate solution

1,5 g of amino-propylene glycol

0,1 mol/l of hydrochloric acid solution

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Recommend a drug for the treatment of tachyarrhythmia epi- sodes:

Dobutamine

Caffeine sodium benzoate

Atropine

Propranolol

Adrenaline

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A 35-year-old female customer came to a pharmacy to purchase a medicine for the prevention of influenza. Which of the following drugs can be recommended?

Lamivudine

Ganciclovir

Ribavirin

Rimantadine

Acyclovir

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Employees of a company can be instructed to go on a business trip by the orders of the company’s head. Specify the deadline for submission of an expense report after the employee’s return from the trip:

3 days

6 days

4 days

5 days

2 days

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A pharmaceutical analyst analyzes a dosage form containing zinc sulfate. What reagent enables him to confirm the presence of the zinc cation in the analyte?

Potassium ferrocyanide

Sodium sulfide

Sodium tetraphenylborate

Ammonium chloride

Silver nitrate

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Lily of the valley is widely regarded as a cardiac stimulant and sedative. During the raw material procurement, the following plant may occur in the harvested crop:

Spring adonis

Round-leaved pyrola

Viola arvensis

Treacle-mustard (Erysimum chei-ranthoides)

Viola tricolor

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A pharmaceutist prepares an infusion at a ratio of 1:30. What herbal raw material will be used?

Shoots of Marsh Labrador tea

Marshmallow root

Oak bark

Sage leaves

Lily of the valley grass

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A pharmaceutist has prepared vaginal suppositories. Specify the form of these suppositories:

Marbles

Torpedo

Cylinder

Sticks

Cone

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Under the SPhU (appendix 2), leaves of ginkgo are standardized by the content of:

Flavonoids

Alkaloids

Saponins

Chromones

Coumarins

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A clinical pharmaceutist invited to a medical conference made a report on the antiviral drug acyclovir. What is its mechanism of action?

It increases the permeability of the cell membrane

It blocks the synthesis of the cell wall

It antagonizes with PABA

It inhibits the synthesis of proteins

It inhibits the synthesis of nucleic acids

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What kind of marketing is provided in case of negative demand for goods and services, that is, in a situation when the demand is absent in a substantial part of the potential market?

Conversion

Demarketing

Remarketing

Stimulating

Synchro marketing

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Prescriptions for the controlled drugs dispensed under the reimbursement program (except for the narcotic and psychotropic preparations in substance) are issued on the following prescription form:

№1 in duplicate

№1, single copy

№3, single copy

№1 and № 3

№3 in duplicate

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In case of the planned closure of a pharmacy for repair works, technical re-equipment or other works, a business entity is obliged to give a written notice to the Territorial State Inspectorate for Quality Control of Medicines in advance, but not later than:

12 days in advance

3 days in advance

5 days in advance

10 days in advance

7 days in advance

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Pharmacy №7 is engaged in both sales and production. What operations ARE NOT REGISTERED in the journal of laboratory and prepacking works?

Preparation of commercially available medications

Packaging of finished products in certain amounts

Preparation of semi-finished products

Extemporaneous compounding of dosage forms

Preparation of concentrated solutions

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Specify a drug having an analeptic and psychostimulant effect:

Caffeine sodium benzoate

Diazepam

Diclofenac sodium

Neostigmine methylsulfate

Corglycon

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What medicines are used to eliminate bronchospasm?

в-blockers

a-adrenergic agonists

Cholinesterase inhibitors

M-cholinomimetics

в-adrenergic agonists

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Alkaloid glaucine has an antitussive effect that is stronger and longer if compared to that of codeine, and exhibits no narcotic side effects. What medicinal plant contains glauci-ne?

Henbane bell (Scopolia carniolica)

Thermopsis lanceolata

Celandine

Yellow hornpoppy

Datura

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Drug plant Dioscorea nipponi-ca is the starting materials for the production of Polysponinum drug which is used in the complex treatment of atherosclerosis. Specify the active compounds of dioscorea:

Essential oil

Triterpene saponins

Steroid saponins

Alkaloids

Cardiac glycosides

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A hypertensive patient had been administered a diuretic as a part of the combined therapy. The administered drug caused hypokalemia. Specify this drug:

Triamterene

Hydrochlorothiazide

Spironolactone

Allopurinol

Amiloride

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A pharmaceutical factory produces herbal juice from fresh raw material. What operation should be performed at the stage of juice purification?

Filtration

Heating followed by rapid cooling

Adsorption

Crystallization

Sedimentation

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Cash receipts and payments at a pharmacy are recorded in the cashbook. Which of the following cash transactions IS NOT REGARDED as a receipt transaction?

Recognizing cash receipts from sales at pharmacy outlets and kiosks

Recognizing cash receipts from sales at a pharmacy

Recognizing accrued salaries and advance payable

Return of unused disbursement funds

Issuing funds to be accounted for

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What system includes a set of legal rules that regulate the amounts, forms, methods and time limits for collecting taxes and tax-like charges that enable the state to perform its functions?

Statistic

Reporting

Tax

Accounting

Remuneration of labor

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Phytochemical workshop of a factory manufactures pancreatin. What is the starting material for obtaining pancreatin?

Heart of cattle

Egg white

Gastric mucosa of pigs

Pancreas of pigs or cattle

Lungs of cattle

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In case of simultaneous use of metronidazole and oral anticoagulants derived from coumarin patients must be warned about:

Potentiation of metronidazole effect

Reduction of metronidazole effect

Higher neurotoxicity

Reduction of anticoagulants effect

Potentiation of anticoagulants effect and the risk of bleeding

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Specify the principle of the pharmacy accounting which complies with the following definition: 'This principle provides for continuous following the adopted accounting policy. Any changes to the accounting policy must be well-grounded and fixed in the financial statements':

Full disclosure

Expenses against revenues matching

Going concern

Periodicity

Consistency

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At a maternity hospital a pregnant woman with weak uterine contractions has been administered oxytocin. This drug relates to the following pharmaceutical group:

Pituitary hormone preparations

Glucocorticoids

Thyroid hormone preparations

Mineral corticoids

Anabolic steroids

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What factor underlies the mechanism of the analgesic effect of morphine hydrochloride?

Inhibition of cholinesterase

Inhibition of phosphodiesterase

Stimulation of adenylate cyclase

Inhibition of histamine receptors

Stimulation of opiate receptors

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Analytical and control laboratory determines quality of fatty oils by using certain chemical indices. Specify the chemical index that is demonstrative of the fatty oil drying:

Saponification number

Iodine absorption number

Ester number

Acid number

Peroxide number

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The head of a pharmaceutical company 'Azalea'applies different types of control. The control which starts with logging in to the system of organization before commencement of work and is exercised through rules, procedures, etc. refers to:

Final control

Preliminary control

Decentralized control

Current control

Centralized control

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A 30-year-old male patient diagnosed with acute osteomyelitis has been administered an antibiotic that is highly effective in penetrating the bone tissue. What drug has been chosen?

Polymyxin-M

Ampicillin

Bicillin 3

Penicillin

Lincomycin

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A pharmaceutist dispensed doxycycline to a patient and recommended to abandon dairy products. What is the reason for such recommendation?

Increased risk of dysbiosis

Dairy products are not digested

Deceleration of the antibiotic absorption

Increase in the antibiotic toxicity

Disruption of digestion process

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Commercial and financial activity of a pharmacy involves using returnable tare. Which of the following containers are returned to the supplier?

Metal cylinders

Glassware

Paper boxes

Packaging materials

Glass-stoppered bottles

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A pharmacy has a set of documents which confirm the ownership of computer programs. Specify the balance sheet item that shows the pharmacy’s property:

Goods

Intangible assets

Low-value equipment

Monetary assets

Stock

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In order to expand its range of activities, pharmacy №12 purchased some manufacturing equipment. What group of economic resources does the manufacturing equipment relate to?

Goods

Incomplete capital investments

Tangible assets

Tara

Fixed assets

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A pharmaceutical analyst added solutions of zirconyl nitrate and alizarin to a drug substance. The reaction produced red color turning into yellow. Specify the analyte:

Sodium iodide

Sodium thiosulfate

Sodium fluoride

Sodium chloride

Sodium bromide

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A pharmaceutical company studies the market situation in terms of a relationship between supply and demand, price level, stock of goods, etc. What is the company’s actual object of study?

Market infrastructure

Market behaviour

Conditions for the market existence

Market scope

Market structure

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During a medical briefing a pharmacy intern was asked about the mechanism of antiatherosclerotic effect of clofibrate (fenofibrate). What is the correct answer?

It lowers triglycerides

It inhibits the cholesterol absorption

It binds bile acids in the small intestine

It has an antioxidant effect

It inhibits the release of free fatty acids from adipose tissue

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What style of behavior in conflict situations involves partial satisfaction of the interests of both parties by mutual concessions with due consideration of all pros and cons?

Compromise

Dominance

Competition

Cooperation

Evasion

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A pharmacy received a formulation for an extemporaneously compounded dosage form. The formula includes phenobarbital compounded with other drugs. Specify the required prescription form:

Form № 1 in duplicate

Form № 3

Form № 2

Form № 1

Form № 2 in duplicate

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A pharmacy has purchased a refrigerator and computer. These fixed assets are placed on the pharmacy’s balance sheet at the following value:

Liquidating

Residual

Amortized

Historic

Market

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Galenic preparations are produced with the use of various extractants. What extractants require pressure as a prior condition for the extraction process?

Dichloroethane, chloroform

Vegetable oils

Methyl alcohol, acetone

Ethanol

Liquefied gases

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In the production of dry extracts the drying of purified extracts may not involve condensation of the the liquid extractions. What equipment should be used in this case?

Shelf drier

Rotary one-flow drier

Vacuum oven

Spray drier

Thermostat

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Buckthorn bark is used as a laxative. Specify the period for procurement of raw material of alder buckthorn bark:

Autumn

Frondescence

The period of full ripeness

Spring, during the circulation of sap

Winter

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A pharmacy received a prescription for phenobarbital tablets written out by a physician of the city clinic to an epileptic patient. Prescripti- ons for this drug must be written out on the following prescription form:

Form № 2

Form № 3 in duplicate

Form № 1 in a single copy

Form № 1 in duplicate

Form № 3 and № 1 in a single copy

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A pharmaceutical analyst has to test the substance of iron sulfate heptahydrate for purity. What reagent should be used to detect zinc cation in the substance?

Barium chloride

Silver nitrate

Potassium ferrocyanide

Sodium tetraphenylborate

Ammonium oxalate

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A pharmaceutical analyst performs the identification of phthalylsulphathiazole (phthalazol). In compliance with the SPhU requirements, the substance is to be heated with resorcinol in the presence of sulfuric acid. The subsequent addition of sodium hydroxide and water results in:

Intensive blue color

Intensive green fluorescence

Extensive yellow precipitate

Red-violet color

Abundant white precipitate

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Under the SPhU, presence of ammonium salts in sodium tetraborate can be detected by method A by using a solution of the following substance:

Sodium tetraphenylborate

Alkaline potassium tetrai-odomercurate

Barium chloride

Potassium ferrocyanide

Silver nitrate

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A pharmaceutical analyst performs the identification test of lidocaine hydrochloride under the SPhU. The identity is determined by the melting point of precipitate which is produced as a result of reaction with a solution of the following acid:

Picric

Citric

Acetic

Thioglycolic

Phosphoric

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A pharmaceutist with 10 years of service legth is on a sick leave due to temporary disability. What allowance is he entitled to?

40 % of the average wage

70 % of the average wage

80 % of the average wage

60 % of the average wage

100% of the average wage

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Pharmacy cashier is responsible for recording all credit and debit transactions. To enter into the books the cash received, a cashier should issue:

Goods receipt note

Cash receipt voucher

Goods delivery note

Receipt note

Cash payment voucher

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Organizational form of business in which a company does not produce goods or services itself but owns other companies’ controlling stake and thereby supervises their activity is called:

Syndicate

Conglomerate

Holding

Cartel

Trust

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The head of a wholesale pharmaceutical company applies modern theories in order to effectively motivate sales staff and determine the amount of remuneration. Specify one of the groups of motivation theories:

Structural

Process

Primary

System

Secondary

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Which of these drugs kept in the pharmacy stock relates to the group of laxatives?

Vicasol

Bisacodyl

Morphine

Atropine

Heparin

‹ Назад

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A pharmacy received a batch of chemotherapeutic agents. Select an antiviral drug:

Acyclovir

Rifampicin

Benzylpenicillin sodium salt

Doxycycline

Isoniazid

‹ Назад

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A 40-year-old patient has a history of bronchial asthma and heart rhythm disorders in form of bradyarrhythmia. Bronchospasm can be eliminated by the drugs of the following pharmacological group:

в-blockers

Muscle relaxants

M-cholinergic antagonists

M-cholinomimetics

Cholinesterase inhibitors

‹ Назад

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