Step 2 - Pharmacy 2014

A sample of biological material contains mercury. Specify the method of mercury isolation:

Steam distillation

Mineralization

Isolation by organic solvents

Destruction

Isolation by acidified alcohol

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A pharmaceutist has to prepare an oil emulsion with menthol. Specify the appropriate way of the active substance incorporation:

Dissolution in oil

Dissolution in the ready emulsion by heating

Dispersion with the addition of ready emulsion

Dissolution in water intended for diluting the primary emulsion

Incorporation into the ready primary emulsion

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It is required to prepare a decoction of bearberry leaves. Specify the ratio of raw materials to the extractant if not indicated in the formulation:

1:10

1:5

1:30

1:400

1:20

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A pharmaceutist prepared an injectable solution of novocaine. What stabilizer had been used?

Stabilizator of Weibel

Sodium bicarbonate solution

Sodium thiosulfate solution

Hydrochloric acid solution

Sodium sulfite solution

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A disabled veteran of the WW2 has been prescribed codeine powder. What is the maximum permissible amount of codeine that can be dispensed by the prescription?

0, 6

1, 2

0,2

0, 1

1, 0

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Certain groups of drugs are subject to strict record keeping and storage in pharmacies. Specify a drug that relates to the group of narcotics:

Clonidine

Dicaine

Ethylmorphine hydrochloride

Analgene

Dephedrinum

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Under the analytical normative documents, atropine sulfate should be titrated with hydrochloric acid solution in the anhydrous acetic acid medium in the presence of the following indicator:

Methylene blue

Methyl orange

Thymol blue

Phenolphtalein

Crystal violet

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Losartan as a part of treatment of arterial hypertension is contraindicated in case of:

Pregnancy

Urine acid diathesis

Hypokalemia

Hyperglycemia

Hyperlipidemia

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Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?

Acetylsalicylic acid

Phenylinum

Ticlopidine

Heparin

Streptokinase

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At the end of the dug action drug addicts develop severe mental, neurological and somatic disorders. This complex of symptoms is called:

Tolerance

Withdrawal syndrome

Cumulation

Tachyphylaxis

Sensibilization

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Patients with heart failure caused by persisting cardiac and coronary vessel dysfunction can be recommended preparations produced from the following herbal raw material:

Aralia roots

Calendula flowers

Barberry roots

Ginseng roots

Hawthorn fruits

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Rutin exhibits P-vitamin activity. What medicinal plant is used as starting materials for the industrial production of rutin?

Herba Polygoni avicularis

Flores Helichrysi arenarii

Fructus Sophorae japonicae

Herba Bidentis tripartitae

Fructus Hippophaes rhamnoides

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A patient came to a pharmacy to purchase cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?

Herba Achilleae millefolii

Folium Uvae ursi

Radix Taraxaci officinalis

Rizoma et radix Sanquisorbae officinalis

Rizoma Calami

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Pharmaceutical warehouse received a batch of herbal raw material of cinnamon rose. Under the State Pharmacopoeia, it is required to test this raw material for the following active substances:

Anthracene derivatives

Flavonoids

Essential oil

Tannins

Ascorbic acid

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Under the analytical normative documents, prior to direct bromatometric determination of arsenous acid anhydride the following substance should be added to the analyzed solution:

Sodium hydroxide

Sodium thiosulfate

Potassium bromide

Sodium chloride

Potassium nitrate

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A pharmaceutical analyst of an analytical laboratory performs quantitative determination of silver nitrate by thiocyanatometry. What indicator is used in this case?

Phenolphtalein

Iron (III) ammonium sulphate

Potassium chromate

Starch

Sodium eosinate

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A pharmaceutical company produces concentrated extracts. Specify the concentration of ethanol in the extractant required for the production:

70-75 %

90-96 %

50-60 %

20-40%

70-90 %

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A factory workshop producing suspensions and emulsions is going to start manufacturing new drugs. What equipment can be used for the ultrasound processing of drugs?

Disintegrator, liquid whistle

Liquid whistle, magnetostrictive source

Rotor-pulsation apparatus, di-smembrator

Centrifugal mixer with rotating housing

Dismembrator, electrical impulse plasmolyzer

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The ointment workshop of a pharmaceutical plant launches production of a new ointment. Specify the manufacturing operation that ensures equal distribution of the drug substance in the base:

Homogenization

Standardization

Pre-packing

Packaging

Preparation of the base

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The aerosol workshop of a pharmaceutical plant uses various groups of propellants in the production. What propellants relate to the group of volatile organic solvents?

Freon (CFCs)

Methylene chloride, ethylene chloride

Vinyl and methyl chloride

Propane, butane, isobutane

Carbon dioxide

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The phytochemical workshop of a pharmaceutical plant manufactures liquid extracts. How many volume parts of the liquid extract can be produced from one weight part of herbal raw material in compliamce with the State Pharmacopoeia?

3 parts

10 parts

5 parts

0,5 part

1 part

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An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?

Bromatometry

Mercurimetric determination

Chelatometry

Nitritometric determination

Iodometry

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A chemist of the production unit for ampouled medicinal preparations analyzes injectable solution of calcium chloride. According to the requirements, the analyzed solution should be colorless. To meet this requirement, the analyte should be compared to:

Water

Alcohol

Acetone

Hydrochloric acid

Chloroform

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What drug is used as the specific antidote in case of intoxication with iron preparations?

Protamine sulfate

Bemegride

Atropine

Penicillamine

Deferoxamine

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Specify the type of capsules which are used for dispensing camphor powders:

Common paper

Paraffin

Parchment

Waxed

Cellophane

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A pharmacy received a formulation for an extemporaneously compounded medication. Specify the document that is used to set the price for such medication:

Certificate of analysis

Certificate of quality

Inventory report

Retail price list for drugs

Cash receipt voucher

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A pharmaceutist has prepared a suspension ointment. Specify the substance used for this type of ointments:

Zinc oxide

Potassium iodide

Protargolum

Ichthyol

Menthol

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Ergot (Secale cornutum) is used as an uterotonic agent in obstetric practice and for the treatmet of cardiovascular diseases. The authenticity of the raw materials is proved by the content of:

Ergotoxine

Ajmaline

Reserpine

Hyoscyamine

Atropine

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Among the given principles of market segmentation select a principle that is used in the study of drug market most often:

Psychological

Psychographic

Behavioral

Socio-economic

Demographic

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Personnel records refer to the following type of documents:

Scientific

Pharmaceutical

Managerial

Reference information

Directive

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A pharmacy received a formulation for eye drops containing 1% solution of pilocarpine hydrochloride. What substance should be used to ensure that the resultant solution is isotonic?

Sodium nitrate

Glucose

Boric acid

Sodium sulfate

Sodium chloride

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A pharmaceutist prepared 10 powders containing atropine sulfate in an amount of 0,00005 per dose. What trituration had been used?

1:50

1:10

1:1000

1:100

1:20

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Which of the following antihypertensive drugs has potassiumsparing effect?

Prazosin

Metoprolol

Triamterene

Diltiazem

Furosemide

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Immunochemical test for detection of opiates in urine is carried out on polystyrene plates with the use of horseradish peroxidase as a label. This method is classified as:

Heterogeneous immunoassay

Homogeneous immunoassay

Homogeneous immunofluorescence

Heterogeneous radioimmunoassay

Heterogeneous immunofluorescence

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When developing the system of marketing communications, a company should consider the characteristics of each tool used for market promotion of a drug. Which of the following characteristics is typical for advertising?

Depersonalization (non-personal communication)

All answers are correct

Non-mass communication

There is no correct answer

Two-way communication

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Quantitative determination of pyridine derivatives is performed by acidimetry in nonaqueous medium. What titrant is used for this purpose?

Sodium thiosulfate

Sulfuric acid

Nitric acid

Perchlorate acid

Sodium hydroxide

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What antiprotozoal agent can be recommended to a female patient with trichomoniasis?

Solusurminum

Metronidazole

Primaquine

Chloridinum

Chiniofonum

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A patient has a history of chronic bronchitis. Recommend him an expectorant which can be purchased at a pharmacy to facilitate the expectoration of thick and viscous mucus:

Salbutamol

Glauvent

Ambroxol

Falimint

Libexin

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What drug from the group of cardiac glycosides can be used as an alternative for strophanthine if it is not available at a pharmacy?

Digitoxin

Corglycon

Adonisidum

Celanidum

Isolanidum

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A pharmacy received the following formulation: Rp.: Xeroformii Picis Liquidae Betulae Olei Ricini 100,0 M.D.S. For wound anointing. Specify the dosage form:

Paste

Hydrophilic ointment

Solution

Combined ointment

Liniment

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What is the most common symptom of atropine intoxication?

Mydriatic pupils with no light response

Myotic pupils with no light response

Hyperhidrosis

Reduction of intraocular pressure

Bradycardia

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In order to detect the presence of thiosulfate ions a pharmaceutical analyst added the excess reagent. The resulting reaction produced a white precipitate which was slowly turning yellow, then brown, and black. What solution was added?

Ammonium oxalate

Silver nitrate

Lead (II) acetate

Barium chloride

Diphenylamine

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Quantitative analysis of boric acid can be performed by alkalimetric titration in the presence of:

Nitric acid

Mannitol

Ammonia buffer

Mercury (II) acetate

Ethyl alcohol

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A customer came to a pharmacy and presented the prescription for Tramadol tablets. For how long such a prescription must be kept at a pharmacy?

1 year, exclusive of the current year

10 years, exclusive of the current year naЕ.01 month, exclusive of the current year

5 years, exclusive of the current year

6 months, exclusive of the current year

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A 6-year-old child with pneumonia had been administered an antibiotic. After treatment the child lost the hearing. What group of antibiotics might have caused this complication?

Macrolides

Cephalosporins

Natural penicillins

Aminoglycosides

Semi-synthetic penicillins

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Suppositories are prepared by various methods such as rolling, pouring, pressing. What base is used in the pouring method?

Cocoa butter

Vaseline

Paraffin

Butyrolum

Coriander oil

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Select the optimal antibacterial drug for the treatment of mycoplasma pneumonia:

Rovamycin

Penicillin

Amoxiclav

Gentamicin

Ampicillin

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Quantitative determination of pesticides in organic extracts after the isolation from the biological material can be done by various methods. What method of quantitative analysis of chlorophos is based on measuring the peak height parameter?

Argentometry

Photometry

Gas-liquid chromatography

Biochemical method

Thin-layer chromatography

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An analytical chemist of the quality control department of a pharmaceutical plant has to determine the average weight of glibenclami-de tablets. How many tablets should be tested for this purpose?

50

5

30

10

20

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A pharmacy received 10 kg of hawthorn tincture which was packaged in 80 ml bottles. This operation should be recorded in the following document:

Cashbook

Consolidated register

Formulation journal

Journal of laboratory and prepacking operations

Receipt for the ordered medication

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Employees of a pharmacy receive hourly rate wage and bonuses based on individual performance. What document is issued when calculating the payroll advance?

Inventory report

Invoice

Cash receipt voucher

Payroll record

Cash payment voucher

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Help a medical student to select an adrenergic drug for the treatment of anaphylactic shock:

Epinephrine hydrochloride

Galazolin

Clonidine

Fenoterolum

Isadrinum

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A 5-year-old child had accidentally drunk a bottle of eye drops. After 30 minutes the child developed shortness of breath, difficult swallowing, voice hoarseness, dilated pupils, hyperthermia. Which of the drugs might have induced the described manifestations?

Novocaine

Adrenaline

Mesatonum

Atropine

Pilocarpine

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A patient purchased peppermint leaves at a pharmacy. What recommendations on infusing this herbal raw material must be given by the pharmaceutist?

The extract is to be immediately filtered after infusing

The extract is to be artificially cooled 15 minutes after infusing

The infusion is to be prepared at room temperature

The infusion is to be prepared on an open fire

The infusion is to be prepared in a tightly closed vessel

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It is required to prepare 50 g of zinc ointment for a patient. What amount of zinc and vaseline must be weighed out by a pharmaceutist?

10,0 and 40,0 g

5,0 and 45,0 g

2,5 and 40,0 g

0,5 and 49,5 g

1,0 and 49,0 g

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Sterilization methods applied for the preparation of drugs under aseptic conditions can be differentiated into physical, mechanical, and chemical ones. Specify the chemical method of sterilization:

Addition of preservatives

Dry heat sterilization

Radiation sterilization

UV light sterilization

Pressure steam sterilization

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A patient had been given an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient developed red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucosa. What is the cause of this complication?

Withdrawal syndrome

Immediate allergy

Local irritation

Tachyphylaxis

Delayed allergy

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What is the mechanism of action of diclofenac sodium?

It activates the synthesis of phosphodiesterase

It blocks cyclooxygenase

It inhibits phosphodiesterase

It activates adenylate cyclase

It inhibits cholinesterase

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In order to identify deoxycorticosterone acetate a pharmaceutical analyst performed a steroid cycle reaction which produced cherry-red color and green fluorescence. What reagent was added?

Concentrated sulfuric acid

Chloroform

Iron (III) chloride solution

Iodine solution

Potassium hydroxide solution

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When investigating the case of drug intoxication, the expert commission should find out, whether intoxication had been caused by opium or omnopon. For this purpose it is required to conduct an addititional test for:

Morphine

Thebaine

Meconic acid and meconin

Codeine

Papaverine

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Within an accounting period a pharmacy has been providing the population with the finished medications. What business transaction will have an effect on increasing inventory of the pharmacy?

Write-off of low-value inventory

Arrivals from the pharmaceutical warehouse

Markdown according to the prepacking journal

Salary accounting

Write-off of goods

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Which of the following nonsteroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?

Nimesulide

Diclofenac

Acetylsalicylic acid

Indomethacin

Piroxicam

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A manufacturing enterprise plans to retail a new drug through the corporate network of pharmacies. What strategy of drug distribution will be used?

Horizontal integration

Flexible

Multi-echelon

Vertical integration

Direct

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When preparing an ointment with castor oil and vaseline a pharmaceutist failed to obtain a homogeneous system. What is the most likely cause of incompatibility between these components?

Immiscibility of the ingredients

Coagulation

Release of water of crystallization

Limited solubility

Adsorption

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In order to identify the toxic substance which was extracted from the acidic aqueous extract by an organic solvent, a toxicologist performed a murexide test which resulted in development of pink coloration. This indicates presence of the following substance in the sample:

Atropine

Strychnine

Barbamyl

Cocaine

Morphine

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Woolly foxglove is used as raw material for the production of the following drug:

Digitoxin

Corglycon

Erysimosidum

Lantosidum

Adonizid

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A 60-year-old female patient has a history of essential hypertension (stage II), ischemic heart disease, bronchial asthma. After the correction of pharmacotherapy, a patient experienced an attack of bronchospasm, and an escalation of dyspnea. What drug had caused the complication?

Propranolol

Aminophylline

Mucaltinum

Nifedipine

Salbutamol

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A pharmaceutical analyst with a 6-year length of service is on a sick leave due to temporary disability. He is entitled to the sickness allowance in the amount of:

30 % of average wage

80% of average wage

70 % of average wage

100 % of average wage

50 % of average wage

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Sage leaves procured for the production of essential oil should be dried at a temperature of:

50-60 °C

25-30° C

100 °C

70-80 °C

60-70 °C

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Which of the following antibiotics can be identified by means of the maltol formation test?

Amoxicillin

Streptomycin sulfate

Doxycycline hydrochloride

Kanamycin monosulfate

Lincomycin hydrochloride

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What is the main mechanism of action that underlies the bactericidal effect of penicillin on the coccal flora?

Inhibition of protein synthesis

Phagocytic activity of leukocytes

Activation of the immune system of the macroorganism

Disruption of synthesis of the microbial cell wall

Damage to the cytoplasmic membrane permeability

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What is the drug of choice for the treatment of acute pyelonephritis in a pregnant woman in the I trimester?

Norfloxacin

Amoxicillin

Chloramphenicol

Gentamicin

Biseptolum

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What is the most suitable drug that can be recommended for the treatment of rhinitis accompanying an ARVI in a 7-month-old child?

Naphthyzin

Pinosol

0,9% warm water solution of NaCl

Boromentol ointment

Galazolin

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What drug may cause the development of constipation in patients undergoing combined therapy for arterial hypertension?

Trimetazidine

Acetylsalicylic acid in small doses

Pananginum

Furosemide

Verapamil

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In a pharmaceutical company both American and Japanese management styles are used. Select a characteristic feature of the Japanese management style:

Short-term employment

Collective responsibility

Individual decision-making process

Fast evaluation and career advancement

Clearly formalized management structure

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Drug A is in the stage of market saturation. In order to push up intensive sales, management of the manufacturing company decided to use the following type of advertising:

Personal sales

Sales promotion

Public relations

Informational

Aggressive

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A person got poisoned with alcohols. What alcohol derivatives are used for the analysis by the method of gas-liquid chromatography?

Alkyl sulfates

Alkyl acetates

Alkyl sulfites

Alkyl nitrites

Alkyl nitrates

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A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the analyte?

Zinc oxide

Sodium hydroxide

Tartaric acid

Iron (III) chloride

Potassium permanganate

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A pharmaceutical analyst tests potassium bromide for magnesium and alkaline earth metals impurity. What solution is used for this purpose?

Hydrochloric acid

Silver nitrate

Sodium edetate

Potassium permanganate

Sodium nitrite

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A patient with a history of essential hypertension has been administered lisinopril. What is the mechani- sm of action of this drug?

It inhibits ACE

It inhibits alpha-adrenergic receptors

It inhibits beta-adrenergic receptors

It stimulates beta-adrenergic receptors

It inhibits M-cholinergic receptors

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A male patient has been administered an antiulcerant that blocks histamine receptors of the gastric mucosa. What drug is it?

Omeprazole

Atropine sulfate

Pirenzepine

Almagelum

Famotidine

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Stimulation of beta-cells of the pancreas causes the hypoglycemic effect of the following drug:

Glibenclamide

Heparin

Retabolilum

Prednisolone

Adrenaline hydrochloride

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A pharmaceutist prepared an ointment by the following formulation: Rp.: Tannini 0,2 Lanolini 3,0 Vaselini 10,0 M. utf. ung.

S. To anoint the affected skin areas. What method of tannin incorporation was used?

Trituration with liquid petrolate in a mortar by Deryagin rule

Water dissolution, emulsification with anhydrous lanolin

Dissolution in molten vaseline

Trituration with an alcohol in a mortar, blending with the base F. Dissolution in liquid petrolate

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Business transactions are displayed in the accounts. The entry in the account ledger that is made to record the incoming of economic resources is called:

Liabilities

Debit

Credit

Assets

Equity

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Within the matrix of Boston Consulting Group, a certain drug refers to a group of products called 'milking cash cows'. Specify the stage of the lifecycle of this drug:

Decline

Maturity

Growth

Withdrawal

Introduction

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An analytical laboratory has been commissioned to prove the presence of ethylenediamine in aminophylli-ne. Which of the following reagents makes it possible to detect ethylenedi-amine?

Sodium hydroxide

Copper (II) sulfate

Concentrated sulfuric acid

Silver nitrate

Barium chloride

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A patient has glaucoma. Recommend him a drug of the M-cholinomimetic group:

Laevomycetin

Sulfacyl sodium

Pylocarpine hydrochloride

Ephedrine hydrochloride

Atropine sulfate

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Advise an internship doctor on why iron preparations should not be administered together with antacids:

This increases intoxication with iron preparations

This causes increased binding to blood proteins

This prevents deposition of iron in the body

This causes malabsorption of iron

This accelerates elimination of iron preparations

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A female patient with pneumonia has been administered doxycycline hydrochloride. This drug relates to the following group of antibiotics:

Macrolides

Aminoglycosides

Cephalosporins

Penicillins

Tetracyclines

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A pharmacy received the goods according to the accompanying documentation. Who is responsible for keeping the record of medicines received by a business entity?

Authorized representative

Materially responsible person

Chief accountant

Trustee

Pharmacist of the pharmacy

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Under the SPh of Ukraine, one of the reactions for the detection of calcium cation presence in drugs is the reaction with:

Hydroxylamine

Sulfuric acid

Glyoxal-hydroxyanil

Hydroxyquinoline

Alizarin

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A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:

Gamma-aminobutyric acid

Acetylsalicylic acid

Citric acid

Mefenamic acid

Ursodeoxycholic acid

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A patient with acute heart failure and cardiac glycoside intolerance was given an injection of dobutamine. What is the mechanism of its action?

Stimulation of M-cholinergic receptors

Inhibition of phosphodiesterase

Stimulation of a1 -adrenoceptors

Block of K+-, Aa+-ATPase

Stimulation of в1-adrenoceptors

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Which of the methods to fill ampoules with injectable solutions makes it possible to protect capillaries from contamination with thick and viscous solutions?

Syringe

Vacuum

Squeezing-through

Vapor condensation

Turbo vacuum

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When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the board members in a joint-stock company?

Limited to the contributions to the statutory fund and their property

Limited to the double amount of deposits

Unlimited and solidary

Limited to the value of their shares

Limited to the amount of deposits

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In order to verify the purity of the essential oil, some ethanol was added into the test tube with peppermint oil. The mixture became turbid. This means that the peppermint oil contains the following impurity:

Ethyl acetate

Phenol

Acetone

Diethyl ether

Fatty oil

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5 % solution of methylcellulose is used as a stabilizer for preparing a suspension of the following drug substance:

Terpine hydrate

Zinc oxide

Magnesium oxide

Bismuth nitrate basic

Starch

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An analytical chemist of the quality control department of a pharmaceutical plant can prove the presence of the cation in the test substance with a solution of potassium:

Ferrocyanide (III)

Chloride

Pyroantimonate

Hydroxide

Nitrate

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Magnesium peroxide identification is performed by the reaction of perchromic acid formation. What color is produced as a result of this reaction?

Red

Green

Blue

Black

Yellow

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A forensic medicine laboratory received some biological material. It was to be tested for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:

Chloroform

Ethanol acidified with oxalic acid

Water acidified with sulfuric acid

Water alkalized with ammonia solution

Propanol acidified with oxalic acid

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Pharmacies prepare injectable solutions. Which solution is prepared without any stabilizer?

Solution of caffeine sodium benzoate

Glucose solution

Sodium bicarbonate solution

Novocaine solution

Sodium thiosulfate solution

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Ammifurinum contains furocumari-nes. These biologically active substances are derived from:

Fruits of large ammi

Fruits of common parsnip

Rhizomes and roots of angelica

Fruits of toothpick ammi

Fruits of psoralea

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Quality of ampouled injection solutions is tested as to various parameters. How many ampullae are to be checked for assessing the quality of sealing (hermeticity)?

97 %

80 %

75 %

50 %

100%

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A pharmacy compounds suspensions. What substance can be used for preparing a suspension without adding the stabilizer?

Camphor

Phenyl salycylate

Menthol

Sulfur

Magnesium oxide

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All employees are entitled to annual leave. What is the duration of the additional leave for pharmacy employees with non-standard working hours?

Thirty calendar days

The additional leave is not granted

Twenty calendar days

Seven calendar days

Ten calendar days

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One of the packagings stored at the warehouse of finished products has a damaged label. It is known that the drug substance in this packaging relates to alkaloids. In course of group qualitative tests for alkaloids the drug substance reacted positively with murexide. Further identification of the drug substance should be limited to the following group of derivatives:

Indole

Quinoline

Tropane

Purine

Isoquinoline

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Industrial, labor and socioeconomic relations between the head of a pharmaceutical company and the employees are regulated by:

Employment agreement

Statute

Contract

Corporate code

Collective agreement

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A pharmacy received the following formulation: Rp.: Dibazoli 0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose:

0, 26

0,27

2, 7

0, 30

0, 25

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Xenobiotics are metabolized in the body. The main metabolite of the acetic acid is:

Acetaldehyde

Isopentyl alcohol

Methyl alcohol

Valeric acid

Formic acid

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Under the SPhU, the pharmacopei-al preparation 'Aether anaestheti-cus'is not allowed to have peroxide impurity. What reagent should be used to detect peroxides?

Lugol’s reagent

Solution of starch and potassium iodide

Grade reagent

Solution of starch and potassium tetraiodomercurate

Solution of starch and potassium bromide

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Arrangement of drugs in the retail space of a pharmacy can be characterized as either strong or weak. What arrangement of drugs is regarded as weak?

Zones with a good frontal look

Cashier desk zone

At the intersection of the ranks of shelves

The shelves on the right side as the buyers pass along

On the lower shelves

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When calculating the personal income tax, the tax social privilege is taken into account. Its rate depends on a certain statutory amount. Specify this amount:

Cost of living for incapacitated persons

Cost of living for children aged 6 to 18 years

Maximum payroll fund

Minimum statutory wage

Cost of living for one person

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Fatty oils containing unsaturated fatty acids are used for the prophylaxis of atherosclerosis. Specify the starting materials of herbal origin that contain fatty oil:

Ispaghula seed

Psoralea fruits

Parsnip fruits

Pumpkin seed

Chestnut seed

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The phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different starting materials. Specify the biogenic stimulators of animal origin:

Peloidinum, humisolum, torfotum, plasmolum, solcoseryl

Liquid aloe extract, aloe liniment, plasmolum

Peloidinum, humisolum, torfotum, Fibs Rro injectionibus

Liquid aloe extract, aloe liniment, aloe juice, biossedum

Vitreous body, placental suspension for injections, plasmolum, solcoseryl

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A pharmacy network received a batch of raw material without analysis protocol. It was identified as marshmallow root by the external charcteristics. The reaction with 5% alkali liquor was positive. This indi- cates the presence of:

Starch

Pectins

Gums

Cellulose

Slimes

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A pharmaceutical analyst tests anhydrous glucose for purity according to the requirements of the SPhU. Inadmissible barium impurity can be detected by using the following acid:

Hydrochloric

Sulphuric

Acetic

Nitric

Perchloric

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The chemical name 1-benzoyl-5-ethyl-5-phenyl-barbituric acid stands for the following substance relating to barbiturates:

Benzobamil

Hexenal

Barbital

Phenobarbital

Benzonal

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What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?

Vinblastine

Novopassit

Ergotamine

Glaucine hydrochloride

Securinine nitrate

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A pharmaceutist prepares 3000 mL of valerian root infusion for a hospital department. The given amount of extract should be infused in a water bath for:

30 minutes

45 minutes

15 minutes

25 minutes

10 minutes

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A pharmaceutist has prepared a solution of menthol oil. Specify the dissolution temperature of the active substance:

60-70 °C

30-40 °C

20-30 °C

40-50° C

70-80 ° C

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Forensic toxicological analysis of a mineralizate revealed copper. For the initial detection of copper ions the following substance is used:

Diphenylamine

Plumbum diethyldithiocarbamate

Sodium diethyldithiocarbamate

Diphenylcarbazide

Dithizone

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A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?

Ethyl mercury chloride

Heptachlor

Dichlorvos

Hexachlorocyclohexane

DDT

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As a result of condensation of substituted malonic esters and urea the derivatives of the following substance are obtained:

Pyridazine

Pyrimidine

Pyrazine

Pyridine

Pyrazole

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Which of the following ophthalmic dosage forms is produced only industrially?

Ophthalmic ointments

Eye drops

Eye rinses

Eye washes

Ophthalmic inserts

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What medication should be used as an antidote to eliminate the respiratory depression caused by an overdose of a narcotic analgesic?

Cordiamine

Naloxone

Aethimizolum

Camphor

Ammonia

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Fenofibrate relates to the following pharmacological group:

Hypnotics

Indirect anticoagulants

Fibrinolysis inhibitors

Hypolipidemics

Antihypertensives

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Which of the following vaginal dosage forms relate to the officinal formula, that is, are prepared in a pharmacy?

Vaginal foams

Vaginal tablets

Vaginal tablets for preparing solutions and suspensions

Vaginal capsules

Pessaries

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The glidants aerosil or magnesium stearate together with talc are added to the excipients in hard gelatin capsules in order to facilitate the following property:

Moisture regulation

Homogenity

Compactibility

Homogeneous mixing

Powder flowability

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A student has been prescribed a tonic. This may be the tincture of the following medicinal plant:

Common yarrow

Black locust

Rhodiola rosea

Purple foxglove

Java tea (orthosiphon aristatus)

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A 25-year-old female patient had been taking antibiotics for 7 days, the disease was complicated by the development of intestinal dysbiosis. This complication should be treated by the drugs of the following group:

Antacids

Adaptogens

Antispasmodics

Probiotics

Choleretics

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Which group of adjuvants includes polyvinyl alcohol used under the SPhU?

Preservatives

Antioxidants

pH adjusters

Prolongators

Isotonizing agents

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Which of the following drugs should be used for prevention of bronchial asthma attacks?

Ambroxol

Salbutamol

Drotaverine

Diphenhydramine hydrochloride

Cromolyn sodium

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A pharmaceutist has to prepare a medication by the following formulation: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place:

Sodium benzoate

Sugar syrup

Mint water

Sodium hydrogen carbonate

Liquoris Ammonii anisatis

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A pharmaceutist prepares an ointment under aseptic conditions on the sterile ointment base, namely the composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technique of ointment preparation is typical for the following substance:

Benzylpenicillin sodium salt

Sodium chloride

Thiamine chloride

Sodium sulfate

Pilocarpine hydrochloride

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Under the chemico-toxicological classification, toxic compounds are grouped according to the method of their isolation from the biological material. What compound can be isolated by steam distillation?

Analgene

Arsenicum

Atropine

Diazepam

Chloral hydrate

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Toxic medicines are isolated from biological material at a certain pH level of the medium. What substance is extracted from acidic aqueous extracts?

Atropine

Chlorpromazine

Cocaine

Caffeine

Morphine

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What drug is indicated in case of taking an overdose of depolarizing muscle relaxants?

Neostigmine methylsulfate

Naloxone

Metoprolol

Magnesium sulfate

Unithiol

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A 20-year-old female patient has been administered bicillin for rheumatic fever prophylaxis. Specify the frequency of bicillin-5 administration:

Once in 3 days

Once a day

Once per week

Once every 3 weeks

Once per month

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A 65-year-old male patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient takes dai- ly 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?

Tachyphylaxis

Hypersensitivity reaction

Withdrawal syndrome

Glycoside intoxication

Food poisoning

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Vincamine alkaloid reduces blood pressure, has a pronounced sedation effect, as well as hemostatic and anti-inflammatory effect. What herb is the source of this alkaloid?

Yellow water-lily

Bluish larkspur

Thick-fruited pagoda tree

Common periwinkle

Northern wolfsbane

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The galenical preparations workshop produces belladonna tincture. Specify the required ratio for this dosage form:

1:1

1:20

1:2

1:10

1:5

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Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:

Silicon

Methyl cellulose

Vaseline, lanolin

Polyethylene oxide

Hydrogenated fat

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A patient with acute heart failure has been administered an adrenomimetic agent. What drug is it?

Dobutamine

Corglycon

Digoxin

Salbutamol

Metoprolol

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Oil liniments are produced with fatty oils used as a base. What kind of oil should be used by a pharmacist if it was not specified in the formulation?

Sunflower oil

Eucalyptus oil

Sesame oil

Cod-liver oil

Petrolatum

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A pharmacy received a formula for an alcohol solution of methylene blue with unspecified alcohol concentration. In this case, a pharmacutist must use ethyl alcohol of the following concentration:

40 %

60%

70 %

90 %

96 %

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Production unit for ampouled medicinal preparations produces procaine hydrochloride solution. This solution is stabilized by adding:

0,1 mol/l of sodium hydrogen carbonate solution

20,0 of sodium hydrogen carbonate

1,5 g of amino-propylene glycol

0,1 mol/l of sodium hydroxide solution

0,1 mol/l of hydrochloric acid solution

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Recommend a drug for the treatment of tachyarrhythmia epi- sodes:

Adrenaline

Propranolol

Atropine

Caffeine sodium benzoate

Dobutamine

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A 35-year-old female customer came to a pharmacy to purchase a medicine for the prevention of influenza. Which of the following drugs can be recommended?

Ribavirin

Rimantadine

Lamivudine

Acyclovir

Ganciclovir

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Employees of a company can be instructed to go on a business trip by the orders of the company’s head. Specify the deadline for submission of an expense report after the employee’s return from the trip:

5 days

4 days

6 days

2 days

3 days

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A pharmaceutical analyst analyzes a dosage form containing zinc sulfate. What reagent enables him to confirm the presence of the zinc cation in the analyte?

Ammonium chloride

Sodium sulfide

Sodium tetraphenylborate

Potassium ferrocyanide

Silver nitrate

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Lily of the valley is widely regarded as a cardiac stimulant and sedative. During the raw material procurement, the following plant may occur in the harvested crop:

Spring adonis

Round-leaved pyrola

Treacle-mustard (Erysimum chei-ranthoides)

Viola tricolor

Viola arvensis

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A pharmaceutist prepares an infusion at a ratio of 1:30. What herbal raw material will be used?

Shoots of Marsh Labrador tea

Oak bark

Sage leaves

Lily of the valley grass

Marshmallow root

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A pharmaceutist has prepared vaginal suppositories. Specify the form of these suppositories:

Marbles

Cylinder

Torpedo

Sticks

Cone

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Under the SPhU (appendix 2), leaves of ginkgo are standardized by the content of:

Chromones

Saponins

Flavonoids

Alkaloids

Coumarins

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A clinical pharmaceutist invited to a medical conference made a report on the antiviral drug acyclovir. What is its mechanism of action?

It inhibits the synthesis of proteins

It inhibits the synthesis of nucleic acids

It increases the permeability of the cell membrane

It antagonizes with PABA

It blocks the synthesis of the cell wall

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What kind of marketing is provided in case of negative demand for goods and services, that is, in a situation when the demand is absent in a substantial part of the potential market?

Demarketing

Stimulating

Synchro marketing

Remarketing

Conversion

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Prescriptions for the controlled drugs dispensed under the reimbursement program (except for the narcotic and psychotropic preparations in substance) are issued on the following prescription form:

№1 in duplicate

№1, single copy

№1 and № 3

№3, single copy

№3 in duplicate

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In case of the planned closure of a pharmacy for repair works, technical re-equipment or other works, a business entity is obliged to give a written notice to the Territorial State Inspectorate for Quality Control of Medicines in advance, but not later than:

12 days in advance

7 days in advance

10 days in advance

3 days in advance

5 days in advance

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Pharmacy №7 is engaged in both sales and production. What operations ARE NOT REGISTERED in the journal of laboratory and prepacking works?

Preparation of semi-finished products

Extemporaneous compounding of dosage forms

Preparation of commercially available medications

Packaging of finished products in certain amounts

Preparation of concentrated solutions

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Specify a drug having an analeptic and psychostimulant effect:

Caffeine sodium benzoate

Neostigmine methylsulfate

Diclofenac sodium

Corglycon

Diazepam

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What medicines are used to eliminate bronchospasm?

в-blockers

a-adrenergic agonists

в-adrenergic agonists

M-cholinomimetics

Cholinesterase inhibitors

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Alkaloid glaucine has an antitussive effect that is stronger and longer if compared to that of codeine, and exhibits no narcotic side effects. What medicinal plant contains glauci-ne?

Celandine

Thermopsis lanceolata

Datura

Henbane bell (Scopolia carniolica)

Yellow hornpoppy

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Drug plant Dioscorea nipponi-ca is the starting materials for the production of Polysponinum drug which is used in the complex treatment of atherosclerosis. Specify the active compounds of dioscorea:

Triterpene saponins

Steroid saponins

Cardiac glycosides

Alkaloids

Essential oil

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A hypertensive patient had been administered a diuretic as a part of the combined therapy. The administered drug caused hypokalemia. Specify this drug:

Spironolactone

Triamterene

Hydrochlorothiazide

Amiloride

Allopurinol

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A pharmaceutical factory produces herbal juice from fresh raw material. What operation should be performed at the stage of juice purification?

Crystallization

Adsorption

Sedimentation

Heating followed by rapid cooling

Filtration

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Cash receipts and payments at a pharmacy are recorded in the cashbook. Which of the following cash transactions IS NOT REGARDED as a receipt transaction?

Return of unused disbursement funds

Issuing funds to be accounted for

Recognizing cash receipts from sales at pharmacy outlets and kiosks

Recognizing accrued salaries and advance payable

Recognizing cash receipts from sales at a pharmacy

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What system includes a set of legal rules that regulate the amounts, forms, methods and time limits for collecting taxes and tax-like charges that enable the state to perform its functions?

Remuneration of labor

Statistic

Tax

Reporting

Accounting

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Phytochemical workshop of a factory manufactures pancreatin. What is the starting material for obtaining pancreatin?

Gastric mucosa of pigs

Egg white

Lungs of cattle

Heart of cattle

Pancreas of pigs or cattle

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In case of simultaneous use of metronidazole and oral anticoagulants derived from coumarin patients must be warned about:

Reduction of anticoagulants effect

Higher neurotoxicity

Potentiation of anticoagulants effect and the risk of bleeding

Reduction of metronidazole effect

Potentiation of metronidazole effect

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Specify the principle of the pharmacy accounting which complies with the following definition: 'This principle provides for continuous following the adopted accounting policy. Any changes to the accounting policy must be well-grounded and fixed in the financial statements':

Periodicity

Expenses against revenues matching

Going concern

Consistency

Full disclosure

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At a maternity hospital a pregnant woman with weak uterine contractions has been administered oxytocin. This drug relates to the following pharmaceutical group:

Pituitary hormone preparations

Mineral corticoids

Thyroid hormone preparations

Anabolic steroids

Glucocorticoids

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What factor underlies the mechanism of the analgesic effect of morphine hydrochloride?

Inhibition of histamine receptors

Stimulation of adenylate cyclase

Inhibition of phosphodiesterase

Inhibition of cholinesterase

Stimulation of opiate receptors

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Analytical and control laboratory determines quality of fatty oils by using certain chemical indices. Specify the chemical index that is demonstrative of the fatty oil drying:

Iodine absorption number

Saponification number

Ester number

Peroxide number

Acid number

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The head of a pharmaceutical company 'Azalea'applies different types of control. The control which starts with logging in to the system of organization before commencement of work and is exercised through rules, procedures, etc. refers to:

Decentralized control

Preliminary control

Final control

Centralized control

Current control

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A 30-year-old male patient diagnosed with acute osteomyelitis has been administered an antibiotic that is highly effective in penetrating the bone tissue. What drug has been chosen?

Ampicillin

Bicillin 3

Polymyxin-M

Lincomycin

Penicillin

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A pharmaceutist dispensed doxycycline to a patient and recommended to abandon dairy products. What is the reason for such recommendation?

Increased risk of dysbiosis

Deceleration of the antibiotic absorption

Disruption of digestion process

Increase in the antibiotic toxicity

Dairy products are not digested

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Commercial and financial activity of a pharmacy involves using returnable tare. Which of the following containers are returned to the supplier?

Glassware

Metal cylinders

Paper boxes

Glass-stoppered bottles

Packaging materials

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A pharmacy has a set of documents which confirm the ownership of computer programs. Specify the balance sheet item that shows the pharmacy’s property:

Goods

Monetary assets

Stock

Intangible assets

Low-value equipment

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In order to expand its range of activities, pharmacy №12 purchased some manufacturing equipment. What group of economic resources does the manufacturing equipment relate to?

Incomplete capital investments

Goods

Tara

Tangible assets

Fixed assets

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A pharmaceutical analyst added solutions of zirconyl nitrate and alizarin to a drug substance. The reaction produced red color turning into yellow. Specify the analyte:

Sodium chloride

Sodium fluoride

Sodium bromide

Sodium thiosulfate

Sodium iodide

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A pharmaceutical company studies the market situation in terms of a relationship between supply and demand, price level, stock of goods, etc. What is the company’s actual object of study?

Market infrastructure

Market behaviour

Conditions for the market existence

Market structure

Market scope

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During a medical briefing a pharmacy intern was asked about the mechanism of antiatherosclerotic effect of clofibrate (fenofibrate). What is the correct answer?

It binds bile acids in the small intestine

It inhibits the release of free fatty acids from adipose tissue

It has an antioxidant effect

It lowers triglycerides

It inhibits the cholesterol absorption

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What style of behavior in conflict situations involves partial satisfaction of the interests of both parties by mutual concessions with due consideration of all pros and cons?

Competition

Evasion

Cooperation

Compromise

Dominance

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A pharmacy received a formulation for an extemporaneously compounded dosage form. The formula includes phenobarbital compounded with other drugs. Specify the required prescription form:

Form № 2

Form № 2 in duplicate

Form № 1

Form № 3

Form № 1 in duplicate

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A pharmacy has purchased a refrigerator and computer. These fixed assets are placed on the pharmacy’s balance sheet at the following value:

Residual

Amortized

Historic

Liquidating

Market

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Galenic preparations are produced with the use of various extractants. What extractants require pressure as a prior condition for the extraction process?

Methyl alcohol, acetone

Vegetable oils

Dichloroethane, chloroform

Ethanol

Liquefied gases

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In the production of dry extracts the drying of purified extracts may not involve condensation of the the liquid extractions. What equipment should be used in this case?

Rotary one-flow drier

Shelf drier

Thermostat

Vacuum oven

Spray drier

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Buckthorn bark is used as a laxative. Specify the period for procurement of raw material of alder buckthorn bark:

Autumn

Frondescence

The period of full ripeness

Winter

Spring, during the circulation of sap

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A pharmacy received a prescription for phenobarbital tablets written out by a physician of the city clinic to an epileptic patient. Prescripti- ons for this drug must be written out on the following prescription form:

Form № 2

Form № 3 in duplicate

Form № 3 and № 1 in a single copy

Form № 1 in duplicate

Form № 1 in a single copy

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A pharmaceutical analyst has to test the substance of iron sulfate heptahydrate for purity. What reagent should be used to detect zinc cation in the substance?

Potassium ferrocyanide

Sodium tetraphenylborate

Silver nitrate

Ammonium oxalate

Barium chloride

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A pharmaceutical analyst performs the identification of phthalylsulphathiazole (phthalazol). In compliance with the SPhU requirements, the substance is to be heated with resorcinol in the presence of sulfuric acid. The subsequent addition of sodium hydroxide and water results in:

Extensive yellow precipitate

Red-violet color

Intensive green fluorescence

Intensive blue color

Abundant white precipitate

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Under the SPhU, presence of ammonium salts in sodium tetraborate can be detected by method A by using a solution of the following substance:

Alkaline potassium tetrai-odomercurate

Sodium tetraphenylborate

Barium chloride

Potassium ferrocyanide

Silver nitrate

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A pharmaceutical analyst performs the identification test of lidocaine hydrochloride under the SPhU. The identity is determined by the melting point of precipitate which is produced as a result of reaction with a solution of the following acid:

Picric

Phosphoric

Citric

Acetic

Thioglycolic

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A pharmaceutist with 10 years of service legth is on a sick leave due to temporary disability. What allowance is he entitled to?

80 % of the average wage

60 % of the average wage

100% of the average wage

40 % of the average wage

70 % of the average wage

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Pharmacy cashier is responsible for recording all credit and debit transactions. To enter into the books the cash received, a cashier should issue:

Goods receipt note

Receipt note

Cash payment voucher

Goods delivery note

Cash receipt voucher

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Organizational form of business in which a company does not produce goods or services itself but owns other companies’ controlling stake and thereby supervises their activity is called:

Trust

Holding

Cartel

Syndicate

Conglomerate

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The head of a wholesale pharmaceutical company applies modern theories in order to effectively motivate sales staff and determine the amount of remuneration. Specify one of the groups of motivation theories:

Process

Primary

Structural

System

Secondary

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Which of these drugs kept in the pharmacy stock relates to the group of laxatives?

Atropine

Morphine

Heparin

Bisacodyl

Vicasol

‹ Назад

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A pharmacy received a batch of chemotherapeutic agents. Select an antiviral drug:

Rifampicin

Benzylpenicillin sodium salt

Acyclovir

Doxycycline

Isoniazid

‹ Назад

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A 40-year-old patient has a history of bronchial asthma and heart rhythm disorders in form of bradyarrhythmia. Bronchospasm can be eliminated by the drugs of the following pharmacological group:

M-cholinergic antagonists

Muscle relaxants

Cholinesterase inhibitors

M-cholinomimetics

в-blockers

‹ Назад

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