Step 2 - Pharmacy 2011
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1 із 200
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1 із 200
During local anaesthetizati-on novocaine solution is usually compounded with solution of adrenaline hydrochloride. What is the purpose of this action?
Vasoconstriction
Algesthesia reduction
Decrease in smooth muscle tone
Vasodilatation
Increase in smooth muscle tone
2 із 200
Which of the below-listed drugs is used for thrombolytic therapy in case of myocardial infarction?
Streptokinase
Acetylsalicylic acid
Ticlopidine
Heparine
rhenylinum
3 із 200
On the 4th day of treatment with indometacin a 55-year-old patient developed gastrorrhagia as a result of gastric mucosa ulcer. Ulcerogenic effect of this drug is explained by the lowered activity of the following enzyme:
Cyclooxygenase-1 (COX-1)
Lipoxygenase (LOG)
Prostacyclin synthetase
Cyclooxygenase-2 (COX-2)
-
4 із 200
A 45-year-old patient has been taking neodicumarinum for thrombophlebitis for two weeks. The regular blood test revealed a decrease in prothrombin concentration, microhematuria. Which drug should be used as neodicumarinum antagonist?
Vicasol
Heparin
Sodium citrate
Protamine sulfate
Aminocaproic acid
5 із 200
A patient complaining of dry mouth, photophobia and blurred vision has been delivered to the admission ward. Objectively: the skin is hyperemic, dry, mydriatic pupils and tachycardia are present. He has been diagnosed with belladonna alkaloids intoxication. Which of the drugs should be given as an antidote?
Neostigmine
Armin
Dipiroxim
Pylocarpine
Aceclidine
6 із 200
A 52-year-old patient was diagnosed with systemic amebiasis accompanied by bowels, liver and lungs affection. What preparation should be administered?
Metronidazole
Chiniofon
Phthalazol
Tetracycline
Chingamin
7 із 200
A gravida in her 20th week of gestation got ill with pneumonia. What chemotherapeutical drug may be administered with no risk for the fetus development?
Веnzylpenicillinum
Gentamycin
Ofloxacinum
Sulfalenum
Laevomycetinum
8 із 200
During a surgical operation the muscle relaxant tubocurarine chloride was used. What antagonist drug should be injected in order to allow the patient to brief independently?
Neostigmine
Dithylinum
Веnzohexonium
Cytitonum
Aethimizolum
9 із 200
A pharmacy depot received a batch of common plantain leaves. According to the requirements of the Pharmacopoeia, this herbal raw matrial is of adequate quality if it contains the following active substances:
Polysaccharides
Essential oils
Tannins
Flavonoids
Anthracene derivatives
10 із 200
A pharmacy analyst analizes distilled water. For this purpose he brings some amount of the sample material to the boiling point, adds 0,02 M solution of potassium permanganate and diluted sulfuric acid. After 5 minutes of boiling the pink colour of the produced solution should not change. The pharmacy analyst tries to detect the following admixture:
Chemical reducing agent
Nitrates
Heavy metals
Sulfates
Carbon dioxide
11 із 200
A pharmacy supplies the population with drugs for cash. Specify the VAT on drugs:
0%
30 %
15 %
10 %
20 %
12 із 200
Aerosol production involves application of different groups of propellents. What propellents relate to the group of compressed gases?
Nitrogen, nitrous oxide, carbon dioxide
Methylene chloride, ethylene chloride
Freons
Propane, butane, isobutane
Vinyl chloride, methyl chloride
13 із 200
An analytical laboratory carries out quantitative analysis of sodium citrate by method of ionexchanging chromatography on a cationite. What titrated solution is to be used for the following titration of generated citric acid?
Sodium hydroxide
Potassium iodate
Hydrochloric acid
Trilon B
Iodine
14 із 200
Which preparation is the specific antidote in case of intoxication with iron preparations?
Deferoxamium
Bemegridum
Atropinum
Penicillamine
Protamine sulphate
15 із 200
A pharmaceutist revealed incompatibility in the formulation. Rp.: Sol. Collargoli 1% - 10 ml Sol. Adrenalini hydrochloridi 0,1% - 1i M.D.S. Nasal drops. What chemical process underlies this incompatibility?
Oxidization
Neutralization
Hydrolysis
Precipitation
Adsorption
16 із 200
A pharmaceutist made a tincture of Adonis herb. A peculiarity of its preparation is that the active substances are derived in:
In the neutral medium
In the alkalescent medium
In the alkaline medium
In the acid medium
In the subacid medium
17 із 200
Coltsfoot preparations are used for upper airways treatment. During procurement of this herbal raw material the following admixture may appear:
Great bur (Arctium lappa)
Common plantain (Plantago major)
Spring adonis (Adonis vernalis)
Marsh mallow (Althaea officinalis)
Pot marjoram (Origanum vulgare)
18 із 200
A pharmacist-technologist received an ointment formulation. Rp.: Unguentum Resorcini 1,5% -10,0 Da. Signa. To be applied on the affected skin The pharmaceutist incorporated dry medical substance into the ointment by the following way:
Triturated with a few vaseline oil drops
Triturated with a few water drops
Triturated with a part of vaseline
Triturated with a few ethanol drops
Added to molten vaseline
19 із 200
For granule drying different types of dryers are used. The dryer SP-30 relates to the following type:
With fluidized bed
With silica gel column
Sublimation
Infrared
With a forced air circulation
20 із 200
Specify the herbal raw material with high concentration of carotinoids which is d used for production of phytopreparations:
Sea-buckthorn fruits
Caseweed grass
Wild strawberry leaves
Currant leaflets
Parsley roots
21 із 200
For the purpose of sales stimulation a pharmaceutical wholesale company grants its customers a discount according to the social contract and on condition of their loyalty. Specify the type of discount:
Bonus
Dealer
Seasonal
-
Discounts for quantity of purchased goods
22 із 200
One of the quality indicators for finished ampoules is lack of residual stress in the glass. Which operation at the stage 'Preparation of ampoules to be filled 'eliminates this imperfection?
Ampoule annealing
Capillary opening
Ampoule washing
Ampoule drying
Ampoule sterilization
23 із 200
Companies producing injectable dosage forms apply different methods of ampoule sealing. Sealing against a jet of inert gases (nitrogen, argon, carbon dioxide) is suitable for the following injection solutions:
Easily oxidable
Thermostable
Hydrolytically unstable
Photosensitive
Viscous
24 із 200
Quality control of tablets produced at a pharmaceutical enterprise involves quantitative determination of such subsidiary substances as talc and aerosil. What method is applied for such determination?
Gravimetric
Titrimetric
Chromatographic
Spectrophotometric
Photocolorimetric
25 із 200
Pharmaceutical plants produce enteric-coated tablets. According to the requirements of the State Pharmacopoeia of Ukraine, the coating mustn’t disintegrate in the acidic medium within the following period:
1 hour
2 hours
4 hours
3 hours
5 hours
26 із 200
A patient with depression has been administered a drug from the group of tri- cyclic antidepressants. Specify this drug:
Amitriptyline
Caffeine
Phenazepam
Droperidol
Aminalonum
27 із 200
In the medical practice this compound is used as a disinfectant. In case of intoxication with this compound the patient’s urine turns olive or olive-black. Specify the compound:
Phenol
Iodoform
Ethyl ether
Isoamyl alcohol
Ethyl lbenzoata
28 із 200
A patient with hypertension has been administered one of antihypertensive drugs. Blood pressure dropped back to normal, but the patient has developed a persistent dry cough. Which of the following drugs has such a side effect?
Enalapril maleate
Nifedipine
Clonidine
Furosemide
Propranolol
29 із 200
A patient suffering from ulcer disease was prescribed famotidine. What is the mechanism of its action?
Block of H2-histamine receptors
Inhibition of adenosine triphosphatase activity
Block of cholinoreceptors of sympathetic ganglions
Block of H і-histamine receptors
Block of muscarinic cholinoreceptors
30 із 200
According to the requirements of the State Pharmacopoeia of Ukraine, a pharmacy analyst determines iron admixture in a preparation by means of citric and thioglycolic acids. What staining indicates presence of this admixture?
Pink
Green
Blue
Yellow
Black
31 із 200
Name the reason for the reduction of anticoagulant effect of syncumar when it is applied in combination with phenobarbital:
Phenobarbital activates microsomal liver enzymes
These drugs are antagonists
Mutual inactivation
Development of syncumar allergy
Phenobarbital inhibits microsomal liver enzymes
32 із 200
Calamus rhizome is likely to be confused with some other plant rhizome that can be found as an admixture in the herbal raw material. Specify the most likely admixture:
Iris rhizome
Althaea roots
Elecampane roots
Phlojodicarpus roots
Valerian rhizome
33 із 200
Tannins can be used as an antidote for alkaloid poisoning. What herbal remedy should be applied in case of such intoxication:
Cinquefoil root
Calamus rhizome
Elecampane root
Althaea root
Rhizome and roots of madder
34 із 200
Tannins have astringent effect and are used for treatment of colitis, enterocolitis, diarrhea. What herbal raw material contains a lot of tannins?
Fructus Myrtilli
Fructus Sambucci nigri
Fructus Frangulae
Fructus Rhamni catharticae
Fructus Ribes nigri
35 із 200
Cardioglycosides of Adonis vernalis are used for heart failure treatment. This plant raw material should be stored:
According to the list B
According to the list A
In metal containers
Protected from CO2
Under normal conditions
36 із 200
A pharmacy manager is writing the monthly 'Inventory report'. What business transactions should be represented in the expenditure item of the report?
Drug sales
Payroll payment
Plant raw material purchases
Amortization charged to operation
Extra-evaluation of laboratorypackaging works
37 із 200
During inventory of a pharmacy the surplus of inventory holdings was revealed. What actions concerning the surplus should be taken by the inventory comission?
Take on charge
Confiscation by superior organization
Abolishment
Immediate realization
Writing-off
38 із 200
A pharmacist made eye drops of pilocarpine hydrochloride and adrenaline hydrochloride solution. A peculiarity of the incorporation of the adrenaline hydrochloride solution is that it is added:
After sterilization, aseptic
In the first place
After dissolving of solids
To the half dose of solvent
After isotoning
39 із 200
A patient has chronic pancreatitis with apparent manifestations of pancreatic exocrine hypofunction. Which of the following drugs would be the most appropriate in this case?
Раncreatinum
Acidin pepsinum
De-Nol
Оmерrаzоlе
Drotaverine
40 із 200
Underground organs of medicinal plants that accumulate the most of active substances should be collected:
After the seeds have ripened and the overground parts died off
At the flowering stage
During the green fruiting
At the stem extension stage
At the budding stage
41 із 200
In Ukraine the out-patients are supplied with narcotic and psychotropic drugs only by prescription. Medicoprophylactic institutions receive prescription blanks (Form 3) from the following source:
Pharmacy storehouse
Typography
Pharmaceutical corporation
City’s health department
Wholesale companies
42 із 200
A patient has been administered powders containing menthol. What is the best way to achieve the required extent of menthol comminution?
To triturate it with alcohol or ether
To triturate it with other components of the formulation
To triturate it with purified water
To triturate it thoroughly with sugar
To triturate it with glycerine or chloroform
43 із 200
Stability of suspensions can be enhanced by substances which increase the viscosity of the dispersion medium. Specify the substance that exhibits such properties:
Glycerol
Dimexid
Ether
Purified water
Ethanol
44 із 200
A doctor prescribed an olive oil emulsion whose composition includes anesthesin. In order that anesthesin can be incorpotated into the emulsion it should be dissolved:
In the oil before emulsifying
In the treated water
In the alcohol and add to the primary emulsion
In the mature emulsion
In the primary emulsion
45 із 200
О-methylation is an important method of organic substances biotransformation in the body, compounds that are subject to such method contain:
Phenolic groups
Nitro groups
Tthiol groups
Carboxyl groups
Amides
46 із 200
Which antiseptic preparation has bactericidal effect due to the formation of atomic oxygen?
Potassium permanganate
Chloraminum
Furacilinum
Aethonium
Silver nitrate
47 із 200
Styles of maize with stigmata containing fatty acids, vitamins, essential oils, saponins and other substances are used as:
Diuretic and choleretic
Sedative and anticonvulsant
Expectorant and antibechic
Bactericidal and astringent
Cardiotonic and antiarrhythmic
48 із 200
One of the tablet coatings is enterosoluble capsule. They get solved in:
Bowels
-
Rectum
Oral cavity
Stomach
49 із 200
It is required to analyse some herbal raw material in form of shiny black drupes up to 6-8 mm in diameter; the bone is large, very firm, spherical, light brown, with a single seed; it has a sweet, slightly astringent taste. This herbal raw material should be qualified as a fruit of:
Bird cherry
Hawthorn
Black chokeberry
Blueberry
Buckthorn
50 із 200
Which of the following non-steroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?
Nimesulide
Diclofenac
Indomethacin
Acetylsalicylic acid
Piroxicam
51 із 200
A pharmaceutist prepared eyedrops with boric acid. What sterilization method was applied?
Sterilization by saturation vapor pressure
Sterilization by gases
Tyndallization
Sterilization by dry heat
By high-frequency current
52 із 200
A pharmaceutist refused preparation of nasal drops to a patient because of incompatibility between collargol and di-medrol written in the prescription. What is the reason for incompatibility between these ingredients?
Coagulation
Eutectic formation
Dissection
Immiscibility
Adsorption
53 із 200
A pharmaceutist was preparing an ointment with ricin oil and Vaseline but failed to get homogenous system. What is the most likely cause of incompatibility between these components?
Component immiscibility
Coagulation
Release of water of crystallization
Adsorption
Restricted solubility
54 із 200
A doctor wrote a prescription for the tincture of digitalis with hydrochloric acid. What is the reason for their incompatibility?
Hydrolysis (with no visible change)
Gassing
Change in colour
Change in odour
Precipitation
55 із 200
At the initial stage of establishing a pharmaceutical enterprise the internal disciplinary regulations should be adopted. One of the primary matters is the duration of the lunch break for the employees. According to the Labour Code of Ukraine, the break duration must be as follows:
Up to 2 hours
Up to 1 hour
Not less than 3 hours
2,5 hours
-
56 із 200
A 26-year-old patient was diagnosed with community-acquired pneumonia provoked by mycoplasma. Choose the appropriate antimicrobial preparation for the patient treatment:
Rovamycine
Amoksiklav
Amoxicillin
Gentamycinum
Веnzylpenicillinum
57 із 200
A 60-year-old patient has essential hypertension stage II, coronary disease, bronchial asthma. After pharmacotherapy correction the patient exhibited a bronchospastic attack, intensified dyspnea. What drug provoked this complication?
Propranolol
Salbutamolum
Еuphyllinum
Nifedipi^
Мucaltinum
58 із 200
After an emotional stress a 60-year-old patient presented with chest pain irradiating to the left arm. Specify a drug that relieves pain in this case:
Nitroglycerine
Diltiazem
Nifedipine
Propranolol
Metoprolol
59 із 200
A 70-year-old patient consulted a doctor about elevated arterial pressure. He has a history of benign hyperplasia of prostate. What drug should be administered in this case?
Doxazosin
Diltiazem
Propranolol
Ем^гИ
Losartan
60 із 200
A pharmaceutist revealed incompatibility in a prescription for powders with ascorbic acid and hexamethylenetetramine. What process takes place when these components are combined?
Mixture dampening
Immiscibility
Eutectic formation
Substances adsorption
Crystallization water exudation
61 із 200
A pharmaceutist made a medicinal preparation according to the following formulation: Rp.: Chloroformii Olei Helianthi Methylii salicylatis ana 10,0 M.D.S. For infriction. Specify the kind of disperse system:
Liniment - solution
Liniment - emulsion
Liniment - extractional
Liniment suspension
Liniment - combined
62 із 200
In order to get registered in state authorities pharmacies as legal persons must possess authorized capital stock. What amount is identified as the authorized capital stock?
The amount recorded in constituent documents
The amount of debts of an enterprise
The amount of noncurrent assets
The amount of fund formation sources
Total assets
63 із 200
According to the current legislation, pharmaceutists get the sickness benefit in case of temporary disability. Specify the source of payment for the first 5 days of being on the sick leave:
Pharmacy expenditures
Reserve fund
Pension fund
Environment stimulation fund
Pharmacy revenues
64 із 200
Which of the listed antibacterial drugs should NOT be administered to a patient with diabetes mellitus type II being treated with glibenclamid?
Co-trimoxazolum
Gentamycinum
Doxycycline
Midecamycin
Benzylpenicillinum
65 із 200
What drug may cause constipation in a patient undergoing combined therapy for arterial hypertension?
Verapamil
Acetylsalicilic acid in small dosages
Panangin
Furosemide
Trimetazidine
66 із 200
A pharmacy plans to purchase and retail goods of different stock record units. Which group of goods does VAT reduction apply to?
Medicaments
Perfumes
Baby food
Optics
Curative cosmetics
67 із 200
Preliminary tests involve using various kinds of indicator paper. Blackening of the indicator paper treated with plumbum acetate indicates that the biological object contains:
Hydrogen sulphide
Sulphuric acid
Sodium hydroxide
Ammonium hydroxide
Hydrogen chloride
68 із 200
An analytical chemist makes a test for the presence of sodium thiosulphate. Select a reagent which allows to detect the thiosulphate ion:
Hydrochloric acid
Magnesium sulfate
Sodium bromide
Potassium iodide
Sodium hydroxide
69 із 200
An analytical chemist determines the admixture of sulphates in the boric acid. What is the main reagent that he has to add:
Barium chloride
Potassium ferrocyanide
Ammonium oxalate
Sodium sulphide
Silver nitrate
70 із 200
In order to arrest stenocardia attacks a patient takes nitroglycerin capsules. What is the rational way of the drug introduction?
Sublingual
Inhalation
Peroral
Rectal
Hypodermic
71 із 200
Recommend a patient with acute bronchitis a mucolytic drug that ease difficulty in expectoration:
Acetylcysteine
Diclofenac sodium
Loratadine
Glaucine
Drotaverine hydrochloride
72 із 200
A patient with atherosclerosis has been administered an anti-atherosclerotic agent. Specify this drug:
Phenofibrate
Dexamethasone
Ascorbic acid
Pyracetam
Phenylbutazone
73 із 200
A pharmacy received a batch of medicines from a pharmacy depot. Specify the drug subject to the controlled substance inventory in pharmacies:
Dicaine
Paracetamol
Novocaine
Acetylsalicylic acid
Analgin
74 із 200
A pharmaceutical company conducted an age-specific segment analysis of the regional antihistamine market. It revealed the lack of antihistamines for children. The company will consider this segment as:
A market niche
A market door
A market share
An unattractive segment
A segment requiring further research
75 із 200
An obtained mineralisate contains sulphates of lead, barium and strontium in form of white precipitation. What procedure will allow to separate the lead sulphate?
Dissolution in ammonium acetate
Conversion into arsine
Dissolution in concentrated sulphuric acid
Conversion into diethyldithiocarbamate
Conversion into carbonate
76 із 200
A pharmacy received the following prescription: 0,0002 g of scopolamine hydrobromide per 1 powder. How much of 1:100 trituration is required for the preparation of 10 powders?
0,2
0, 04
2, 0
0, 4
4, 0
77 із 200
A pharmacy received a prescription for 3% alcohol solution of boric acid. What concentration of ethyl alcohol is required for preparing the drug form?
70%
60%
96%
40%
90%
78 із 200
A licensed state-owned pharmacy obtains and retails narcotic drugs. Which state authority develops and revises the list of the drugs allowed in Ukraine?
State servise on Narcotic Drugs Control of Ukraine
State Pharmacological Centre
-
State Inspectorate for Quality Control of Drugs
Public Joint Stock Company 'Medicaments of Ukraine'
79 із 200
A pharmacy is engaged in retail sales of drugs. What group of drugs does atropine sulphate relate to?
Toxic
Drastic
Psychotropic
Narcotic
Over-the-counter
80 із 200
An employee of a pharmaceutical company has been commissioned with marketing research on the regional market of antiarrhythmic drugs. What stage of research would he prefer in the first place?
Collection and analysis of secondary information
Analysis of primary information
Submission of report
Collection of primary information
Preparation of report
81 із 200
A pharmaceutical company 'Pfizer'is focused on offering the best quality goods at a high price which should cover the costs of research and development as well as production of high quality products. Despite the high price, the product is still in demand. What are the goals of the company’s price policy?
Winning the market leadership in respect of product quality
Increasing the market share
Increasing the company’s assortment
Maintaining status quo
Ensuring the company’s survival
82 із 200
A pharmaceutical company 'Pharmasvet'has patented and produces now a new hypoglycemic preparation. The company markets this product directly through the own sales departments, affiliated sales companies, pharmacy network. Marketing policy of this pharmaceutical company can be characterized by the channel of the following level:
Zero level
Two-level
Three-level
One-level
Four-level
83 із 200
A patient with cholelithiasis was prescribed the following drug for the purpose of cholesterol gallstone dissolution:
Ursodeoxycholic acid
Citric acid
Mefenamic acid
Acetylsalicylic acid
Gamma-amino-butyric acid
84 із 200
Which of the listed methods of filling ampoules with injectable solutions can protect the capillaries from contamination with thick and viscous solutions?
Syringe method
Steam condensing method
Turbo-vacuum method
Vacuum method
Solution squeezing method
85 із 200
Production of injection solutions involves an operation of solution filtration. What filters are used for sterile filtration?
Filter candles
Filter developed by the Kharkiv Chemo-pharmaceutic Research Institute
Pressure filters
Mushroom filter
Nutsch filters
86 із 200
A 68-year-old female patient has been continuously taking furosemide for heart failure treatment. What drug should be used to prevent hypokalemia in patients taking furosemide?
Panangin
Trimetazidine
Atp-long
Mildronatum
Sustac forte
87 із 200
Eye drops are prepared with an ointment base which is an alloy of vaseline and lanolin. Specify the method of its sterilization:
Dry heat
Tyndallization
Pasteurization
Flowing steam
Ethylene oxide
88 із 200
Quantitative determination of silver nitrate is done by method of thi-ocyanatometry. What indicator is used in this case?
Iron (III) ammonium sulphate
Phenolphtalein
Potassium chromate
Methylene blue
Sodium eosinate
89 із 200
An analytical chemist was identifying xeroform in reaction with sodium sulphide. As a result of reaction a black solid dropped out. What ion was detected?
Bismuth
Copper
Zinc
Silver
Lead
90 із 200
During the chemico-toxicological study of the dialysate of an aqueous extract, the ammonia test IS NOT carried out if the dialysate includes the following substance:
Hydrogen sulphide
Sulphurous acid
Sulphuric acid
Nitrous acid
Nitric acid
91 із 200
A forensic chemical laboratory received an object for analysis. The analysis involves quantitative determination of mercury by means of a reaction with di-thizone. What physicalchemical method is used within this analysis?
Extraction photocolorimetry
Thin layer chromatography
Gas-liquid chromatography
IR spectrophotometry
UV spectrophotometry
92 із 200
A woman in the III trimester of pregnancy has an acute respiratory viral disease accompanied with body temperature rise up to 39oC. Which of the drugs should be recommended?
Paracetamol
Indomethacin
Acetylsalicylic acid
Celecoxib
Diclofenac sodium
93 із 200
Suspensions as heterogenous systems can be characterized by kinetic and sedimentary instability. What substance is used for increasing suspension stability with hydrophobic substances?
Gelatose
Sodium chloride
Sodium sulphate
Glucose
Boric acid
94 із 200
A patient presents with morphine intoxication. Which drug should be injected as an antidote?
Naloxone
Bemegride
Atropine sulphate
Lobeline hydrochloride
Unithiol
95 із 200
Most alkaloids are isolated from the biological material by polar solvents. Which of the listed alkaloids is isolated by the way of distillation with water vapour?
Coniine
Atropine
Cocaine
Quinine
Strychnine
96 із 200
Comparative analysis of the performance of two pharmacies showed that the trade stock in terms of days was 20 and 30 days respectively. Which of these indicators is NOT USED for calculating the trade stock?
Wage fund
Turnover
The left-over goods in terms of settlement prices
The rate of trade mark-up
Sales volume
97 із 200
A pharmacy received drugs that are included in the National List of Essential Medicines. When supplying these drugs to the public hospitals, pharmacies are entitled to mark-up the drug charges at the rate of:
10%
50 %
40 %
20 %
30 %
98 із 200
Sales of medical cosmetics retailed in pharmacies are taxable at the VAT rate of 20%. Who is charged with it?
End consumer
Wholesale intermediator company firm
Product manufacturer
Pharmacy
Customs service
99 із 200
A patient who has been suffering from gastric diseases for a long time is found to have hyperchromic anemia. Which of the following drugs is applied for this pathology treatment?
Сyanocobalamine
Охуferriscorbone
Ascorbic acid
Unitiol
Ferrum Lek
100 із 200
Essential oil of rose is used as an antiinflammatory and antispasmodic agent. It is localized in the following excretory organs:
Glandular spots
Essential oil glandules
Glandular hairs
Essential oil conceptacles
Secretory cells
101 із 200
A chemist of an analytic laboratory has to prepare turbidity standards according to the requirements of Pharmacopoeia. What substances are to be used as the reference?
Hexamethylenetetramine and hydrazine sulphate
Sodium chloride and calcium nitrate
Calcium sulphate and glycerin
Furacilinum and calcium chloride
Potassium chloride and barium sulphate
102 із 200
A pharmaceutist plans voluntary termination of the open-ended employment contract for the reason of her husband’s transfer to another area. Specify the form and term of notice that should be given to the pharmacy director:
Two-week notice in written form
Five-day notice in written form
Two-day notice in written form
One-week notice in written form
One-month notice in written form
103 із 200
A pharmacy makes wholesale purchases of health and hygiene products. An agent works under the contract with the manufacturer and makes deals at the manufacturer’s cost. The agent may be entitled to exclusive distribution in some regions. What kind of agent is it?
Wholesale agent
Commission agent
Consignee
Broker
Dealer
104 із 200
How much water should be taken in order to prepare 200 ml of aqueous extract of motherwort ( water absorption coefficient = 2 ml/g)?
240 ml
220 ml
160 ml
210 ml
200 ml
105 із 200
During the identification of a drug an analytical chemist of the State Inspectorate for Quality Control performs a lignin test. Specify this drug:
Streptotcid
Methionine
Analgin
Cortisone acetate
Ascorbic acid
106 із 200
A pharmacist-analyst carries out quantitative analysis of procaine hydrochloride. Which of the following solutions is to be used?
Sodium nitrite
Potassium bromate
Sodium thiosulfate
Sodium edetate
Argentum nitricum
107 із 200
The main active components of hawthorn berries are flavonoids. What is their pharmacological effect?
Hypotensive and sedative
Antispasmodic and anti-inflammatory
Diuretic and styptic
Tonic and antispasmodic
Laxative and sedative
108 із 200
Name a 'metal poison'which is isolated from the biological material by the method of destruction:
Mercury
Cadmium
Silver
Arsenic
Stibium
109 із 200
Toxic substances can be isolated from the objects of biological origin by different methods. In case of intoxication with pesticides - derivatives of phosphoric acids - the following method is applied:
Infusion with organic solvents
Dialysis from alkalized solutions
Distillation with water steam from the alkaline medium
Infusion with alkalized water
Infusion with water acidified with chloric acid
110 із 200
A pharmacy analyst carries out purity test of the drug substance 'Sodium thi- osulfate'. Violet colour, that comes from reaction with sodium nitroprusside, indicates the presence of the following admixture:
Specific sulfides admixture
Sulfur admixture
Sulphates admixture
Sodium chloride admixture
Iodides admixture
111 із 200
An analytic laboratory received 'Aether anaestheticus'for analysis. Which reagent should be used for detection of acetone and aldehyde admixtures according to the State Pharmacopoeia of Ukraine?
Alkaline solution of potassium tetrai-odomercurate
Aqueous solution of potassium iodide
Hydroxylamine solution
Sodium hydrosulphite
Ammonium solution of argentum nitrate
112 із 200
Activity of an organization depends on various factors. What factors refer to the internal environment of the organization?
Abilities, skills and talent of staff
Economy status
Public authorities
Infrastructure
Consumers
113 із 200
Financial accountability of pharmacies consists of separate account forms. Which form presents accounts payable for the goods purchased?
Balance sheet, form 1
Balance assets, form 1
Net worth statement, form 3
Financial performance report, form 2
Financial performance report, form 2m
114 із 200
In Ukraine natural persons as small business entities are allowed to use the simplified tax system. What limit on the number of employees is established for such enterprises?
No more than 10 persons
No more than 20 persons
No more than 50 persons
No more than 30 persons
No more than 40 persons
115 із 200
For the natural persons being small business subjects the simplified tax system is effective. But there is a limit of annual proceeds upon sale. What is the boundary amount of proceeds?
Up to 500 thousand UAH
Up to 750 thousand UAH
Up to 5 million UAH
Up to 1 million UAH
Up to 100 thousand UAH
116 із 200
Simplified tax system implies replacement of several taxes by a single one. What limit on the number of employees is established for the legal persons to implement the simplified tax system?
50 persons
100 persons
75 persons
10 persons
25 persons
117 із 200
Fatty oil containing saturated fatty acids is used for atherosclerosis prevention. Specify the medicinal plant that is used for oil production:
Flax seeds
Hawthorn fruits
Black chokeberry fruits
Fennelflower seeds
Dill seeds
118 із 200
A tablet shop produces trituration tablets. What quality indicators ARE NOT relevant for these tablets?
Abrasion, resistance to crushing
Homogeneity of content
Disintegration and dissolution
Microbiological purity
Homogeneity of dosage
119 із 200
A phytochemical production unit produces biogenic stimulators out of different raw materials. Specify the biogenic stimulators of organo-mineral origin:
Peloidinum, Humisolum, Torfotum, Fibs pro injectionibus
Vitreous body, Placenta injection, Рlasmolum, Solcoseryl
Extractum Aloes fluidum, Linimentum Aloes, Succus Aloes, Biosedum
Peloidinum, Humisolum, Torfotum, Рlasmolum, Solcoseryl
Extractum Aloes fluidum, Linimentum Aloes, Рlasmolum
120 із 200
A pharmaceutical enterprise produces water solutions. The solution of the following substance is produced by method of chemical interaction and electrochemically:
Aluminum hydroxide acetate
Potassium arsenite
Plumbum hydroxide acetate
Polyvinyl alcohol
Calcium gluconate
121 із 200
In course of preparation of suppositories by the pumping method the suppository mass became viscous and fluid after the incorporation of chloral hydrate into the cocoa butter. What substance should be added to the suppository mass in order to restore its density and plasticity?
Wax
Glycerine
Starch
Purified water
Dimexid
122 із 200
Powders make up an important group among the extemporal medicinal preparations. Which of the following components can be incorporated into a powder without being preliminarily ground?
Basic Bismuth nitrate
Calcium gluconate
Camphor
Ascorbic acid
Xeroform
123 із 200
Qualitative reaction for phenol is the reaction with bromine water. What compound is produced as a result of the interaction of phenol with bromine water and drops out as a white solid?
2,4,6-tribromophenol
2,4-dibromophenol
3- bromophenol
2- bromophenol
4- bromophenol
124 із 200
Upper airways diseases can be treated by means of herbal raw materials containing mucilages. The plant source of this compound class is:
Radix Althaeae
Radix Belladonnae
Radix Ipecacuanhae
Radix Inulae
Radix Rhodiolae
125 із 200
The basic structure of steroid hormones is hydrocarbon skeleton -cyclopentane perhydrophenanthrene. What natural compound is used for testosterone propionate production?
Cholesterol
Indole
Phenanthrene
Anthracene
Naphthalene
126 із 200
According to the requirements of the State Pharmacopoeia of Ukraine, a pharmacy analyst should determine procaine hydrochloride by nitritometric method. What indicator is to be used for this purpose?
Neutral red
Acid chrome blue
Methyl red
Xylenol orange
Crystal violet
127 із 200
According to the requirements of the State Pharmacopoeia of Ukraine, a pharmacy analyst should determine fluorouracil by method of nonaqueous titration. What titrated solution is to be used?
Tetrabutyl ammonium hydroxide
Sodium edetate
Ammonium thiocyanate
Potassium bromate
Sodium nitrite
128 із 200
An analytical chemist analyses the substance of ethylmorphine hydrochloride. The substance purity is tested by method of semi-microanalysis. What reagent is used to determine the water admixture?
Iodosulphurous
Molibdeno-vanadium
Methoxyphenyl acetic acid
Biuretic
Hypophosphite
129 із 200
An analytical laboratory carries out an analysis of ferrum sulphate heptohydrate according to the requirements of the State Pharmacopoeia of Ukraine. The test portion of the substance should be titrated with the following solution:
Ammonium cerium sulfate
Potassium bromate
Sodium edetate
Ammonium thiocyanate
Argentum nitrate
130 із 200
A patient consults a pharmaceutist about taking acetylsalicylic acid as an antiaggregant. What is the daily dose that should be recommended for continuous use?
0,1-0,3 g
2,0-3, 0
0,5-1,0 g
Over 4,0 g
1,0-2,0 g
131 із 200
The main active components of senna leaves and fruits are sennosides A, B, C,
Anthracene derivatives
Iridoids
They relate to the following class of biologically active substances:
Phenolic acids
Flavonoids
132 із 200
A laboratory received some herbal raw material for analysis. It is a composition of ovoidpointed leaves up to 25 cm long and 20 cm wide; the leaf base is cuneate, the leaf edge is emarginate. The cutting is long and cylindric. The leaf venation is pinnatisect; the midrib and the first-order veins project significantly on the inferior surface of the leaf. The superior leaf surface is dark green, the inferior surface is light green. The plant has a weak narcotic smell. The taste cannot be determined. The plant is poisonous! The described herbal raw material relates to the following plant:
Datura stramonium
Vinca minor
-
Chelidonium majus
Passiflora incarnata
133 із 200
It is necessary to prescribe nonsteroid anti-inflammatory drug for patient with rheumatoid arthritis and concomitant duodenal ulcer. Which drug is the drug of choice in this case?
Celecoxib
Diclofenac sodium
Acetylsalicylic acid
Paracetamol
Analgin
134 із 200
A pharmaceutist is preparing powders according to the following formulation: Rp.: Scopolamini hydrobromidi 0,0003 Ephedrini hydrochlorodi 0,05 Sachari 0,15 M.f. pulvis
0,20
t.d. № 10 S. 1 powder thrice a day. Calculate the mass of 1 powder providing that the trituration (1:100) is used:
0, 23
0, 15
0, 17 F. 0,203
135 із 200
A pharmaceutist prepares several different solutions with antibiotics under aseptic conditions. He can sterilize the solution of the following substance:
Chloramphenicol
Benzylpenicillin-sodium
Polymyxin sulphate
Benzylpenicillin-potassium
Neomycin sulphate
136 із 200
A pharmaceutist has revealed an incompatibility in the prescription. What drug substances form an eutectic mixture?
Chloral hydrate + camphor
Ephedrine hydrochloride + glucose
Calcium chloride + sodium chloride
Antipyrine + analgin
Sodium hydrocarbonate + hexamethylenetetramine
137 із 200
The risk can arise from some forms of activity connected with production of goods and services, their selling, commodity-money and financial operations, commerce, implementation of socioeconomic and scientific-and-technical projects. This is the definition for the following concept:
Business risk
Labour loss
Loss of property
Financial loss
Loss of time
138 із 200
While studying the reaction of an 'acid'chloroform extraction in acidic medium with sodium nitrite, a forensic toxicologist got a compound stained emerald green. Which of the substances is capable of forming the mentioned ni-trose compound?
Antipyrine
Analgin
Noxiron
Amidopyrine
Salicylic acid
139 із 200
A patient got poisoned with nitrites. Nitrite detection by means of azo dye reaction involves using such acid:
Sulphanilic
Phosphoric
Sulphuric
Hydrochloric
Salicylic
140 із 200
Preparations made out of eleutherococcus roots and rhizomes are administered as a tonic and adaptogenic drug. If these preparations cannot be found in a pharmacy, they can be substituted by the analogous preparations made of the following raw material:
Ginseng roots
Polemonium roots
Acorus calamus roots
Rhizomes and roots of valerian
Elecampane roots
141 із 200
A patient with bronchial asthma has been administered a drug from the group of betaadrenergic agonists. Specify this drug:
Salbutamol
Diazepam
Nitroglycerine
Doxycycline hydrochloride
Digoxin
142 із 200
An analytical chemist determines the quantitative content of caffeine by method of acidometry in nonaqueous media in compliance with the State Pharmacopoeia of Ukraine. What solution is used as a titrant?
Perchloric acid
Potassium bromate
Sodium edetate
Sodium hydroxide
Sodium nitrite
143 із 200
A pharmacy analyst identifies sodium hydrocarbonate. What indicator can confirm the presence of alkalescent medium reaction in the sodium hydrocarbonate solution?
Phenolphtalein
Starch
Ferroin
Tropeolin 00
Naphtholbenzein
144 із 200
Substance of calcium pangamate is to be studied in n analytical laboratory. Calcium cation forms a white precipitate with the following reagent:
Ammonium oxalate
Sodium cobaltinitrite
Potassium permanganate
Sodium chloride
Potassium bromide
145 із 200
A chemist of an analytical laboratory studies procaine hydrochloride according to the requirements of the State Pharmacopoeia of Ukraine. What method is recommended by the State Pharmacopoeia of Ukraine for the quantitative analysis of this preparation?
Nitritometry
Acidimetry
Chelatometry
Bromatometry
Alkalimetry
146 із 200
A patient has been administered a spasmolytic from the group of muscarinic receptor antagonists as a part of the complex treatment for renal colic. Specify this drug:
Atropine
Neostigmine
Dithylinum
Benzohexonium
Galantamine
147 із 200
A common method for quantitative determination of drugs from the group of alkali metal halogenides is:
Argentometry
Alkalimetry
Chelatometry
Nitritometry
Permanganatometry
148 із 200
A patient has been taking isosorbi-de for stenocardia prevention for quite a long time. Now he notes a significant decrease in the effect of the drug. What is this phenomenon called?
Tolerance
Cumulation
Allergy
Physical dependence
Potentiation
149 із 200
Pharmacy activities are commonly operated by different types of managers. The function of direct control over drug preparation by a pharmaceutist refers to the following type of management:
Technical
Administrative
Institutional
Managerial
Bureaucratic
150 із 200
A pharmaceutist has applied for a job of a stockkeeper at a wholesale pharmaceutical enterprise. What trial period doesn’t require agreement with the trade-union committee?
Up to three monthes
Up to four monthes
Up to two monthes
Up to six monthes
Up to one month
151 із 200
Marketing manager at a pharmaceutical factory is planning its communication policy. Which component of the marketing communication systems has the highest value for one contact?
Personal sale
'Public relations'
Periodical advertising
Sales promotion
TV advertising
152 із 200
During the treatment of chronic heart failure with digoxin in a patient having bradycardia, nausea, vomiting, blurred vision. Which drug is the antidote in this case?
Unithiol
Amyl nitrite
Tetacinum calcium
Dipiroximum
Atropine sulphate
153 із 200
A biennial or perennial plant from the Apiaceae family has a blue-grey stem branching in its lower part. Its leaves are also blue-grey, finely dissected, with the ultimate filiform segments. The flowers are yellow, in compound umbels. Its fruit is used for production of 'dill water'. What plant is it?
Foeniculum vulgare
Coriandrum sativum
Carum carvi
Petroselium crispum
Conium maculatum
154 із 200
Incoming control is conducted in the course of wholesale and retail trade, such control is carried out during receipt of goods by visual inspection or analysis of drug. Incoming control is carried out by authorized person, which is assigned by:
Managers order
The order of head of territorial inspection
Head of regional structure
Proprietor of an enterprise
State inspection of drugs quality control
155 із 200
When a pharmacy records goods as received, it normally specifies the amount of the markup intended for expenditure coverage and profit gaining. Give the definition for the markup:
The difference between the sale price and purchase price of goods
The difference between the sales price and the customs price
Rummage (goods remains) at the end of the month
The difference between the sales price and markup
The amount of goods sold
156 із 200
Before the raw plant material is taken over from the supplier, it must be checked for compliance. Which document is the ground for recording raw plant material as received in the pharmacy in case of its approval?
Acceptance certificate
Consignation note
Write-off certificate
-
Invoice
157 із 200
The relationships between the demand, supply and price level is studied within the following field of complex market research:
Studies of economic environment
Analysis of market segmentation
Studies of market and product requirements
Analysis of sociopsychological features of buyers
Studies of market structure of companies
158 із 200
According to the Labour Code, compulsory deductions from the salaries of pharmacy employees include:
Pension contributions
Amounts to be withheld under writs of execution
Trade union contributions
Alimony
Excess payments
159 із 200
According to the basic regulations for supply of medical products, pharmacies should be supplied with medicaments having a remaining shelf life of no less than ... %, and bacterial preparations of no less than ...%:
60%, 40%
40 %, 20%
80 %, 60%
50 %, 40%
60 %, 30%
160 із 200
A patient with chronic bronchitis wants to buy glaucine hydrochloride at a pharmacy. What typical side effect of the drug should the patient be warned against?
Drop of arterial pressure
Rise of intraocular pressure
Excitation of the central nervous system
Irregular heartbeat
Allergic skin rash
161 із 200
A 30-year-old patient with a sleep disorder and psychoemotional disbalance has been administered diazepam. What is the mechanism of its psychosedative action?
Activation of GABAergic system
Inhibition of the limbic system
Inhibition of the reticular formation
Reduction of noradrenaline amount in the CNS
Inhibition of opioid receptors
162 із 200
Benzylpenicillin sodium is not used per os, because this drug:
Destroys gastric HCl
Reduces formation of gastric HCl
Poorly absorbed in the intestine
Is destroyed by penicillinase
Irritates gastric mucosa
163 із 200
Select the reductant required for the determination of arsenic impurity in drugs (method 2):
Sodium hypophosphite
Hydrochloric acid solution
Sodium sulfite solution
Potassium iodide solution
Sodium hydroxide solution
164 із 200
A pharmacy received a prescription for powders with a too high single dose of phenobarbital not justified by proper documentation. What actions should a pharmaceutist take?
Put the stamp 'invalid' and return the prescription to the patient
Supply 1/3 of the maximum single dose
Supply the highest single dose
Supply 1/3 of the maximum single dose, multiplied by the number of powders
Supply the maximum single dose, multiplied by the number of powders
165 із 200
When heroin comes into an an organism, it metabolizes chiefly to:
Morphine and 6-monoacetylmorphine
Morphine
3- acetylmorphine and morphine
Codeine
6- acetylmorphine
166 із 200
A pharmacy received a prescription for a topical powder including a substance that is hard to disperse. Which of the listed fluids may be used for dispersing the substance?
Diethyl ether
Isopropyl alcohol
Purified water
Dimexid
Water for injections
167 із 200
A female has prolonged labour. Select a drug that stimulates labour activity due to its physiological effect from the listed below:
Oxytocin
Estrone
Progesterone
Neostigmine
Pachycarpine
168 із 200
A pharmaceutist has to prepare suppositories with a glycerine gelatin base by the molding method. What is the ratio of gelatin, water and glycerine required for the base?
1:2:5
3:2:3
2:2:4
1:3:4
2:1:5
169 із 200
While filling hard gelatin capsules such glidants as 0,1% - 0,3% aerosil or magnesium stearate along with 0,5% - 1% talc are often added to the filling agent in order to improve the following properties:
Flowability
Ability to contact molding
Regulation of moisture content
Homogeneity of mixing
Homogeneity
170 із 200
Prescriptions for drugs being subject to the stocktaking and supplied on favourable terms or free of charge except for narcotic (psychotropic) drugs and tramadol are written out:
In 2 copies of form F-1
On the form F-1
On the pink form
On the forms F-3 and F-1
On the form F-3
171 із 200
What management style is characterized by manager’s particular compliance, when manager initiates goals formation by his subordinate and is ready to accept it without reservations?
Laissez-faire management style
Democratic management style
Bureaucratic style
Collective style
Combined style
172 із 200
Activity of pharmaceutical institutions is subject to licensing. What is the duration of licencse for drugs and healthcare products sale?
Five years
Two years
One year
Four years
Three years
173 із 200
In case of loss of license a pharmaceutist should address an application for a duplicate to a licensing authority. The licensing authority is obliged to issue the duplicate to the applicant no later than:
Three working days from the date of application receipt
Two monthes from the date of application receipt
The duplicate isn’t issued
One month from the date of application receipt
Three monthes from the date of application receipt
174 із 200
Which component of the marketing communication system focuses on creating a positive image of a company?
Public relations
Advertising
Personal sales
Retail logistics
Merchandising
175 із 200
Select a loop diuretic of strong, emergency and short-term action from the listed below:
Furosemide
Spironolactone
Clopamide
Triamterene
Acetazolamide
176 із 200
A laboratory received some herbal raw material for analysis. The plant had flowerheads up to 4 cm in diameter, the marginal flowers were agamic, blue, funnel-shaped; the inner flowers were bisexual, purple, tubular. What plant has these features?
Centaurea cyanus
Scutellaria baicalensis
Viola tricolor
Solidago virgaurea
Polygonum persicaria
177 із 200
Spesify the type of the following liniment: Ol. Helianthi 7,4 Sol. Ammonii caustici 25 ml Ac. Oleinici 0,1 M.f. linimentum D.S. To be rubbed in.
Liniment, emulsion o/w
Combined liniment
Liniment-solution
Liniment-suspension
Liniment, emulsion w/o
178 із 200
A patient who has been undergoing combined drug therapy for peptic ulcer presents with black feces. Specify a drug that might have caused such a change:
Bismuth subcitrate
Actovegin
Metronidazole
Ranitidine
Omeprazole
179 із 200
A man with a long history of chronic hepatitis has been diagnosed with pneumonia. Which of the following antibacterial drugs can be applied in this clinical situation?
Amoxicillin
Vancomycin
Biseptol
Rifampicin
Tetracycline
180 із 200
A 57-year-old female patient was diagnosed with rheumatoid arthritis; she has also a history of stomach ulcer. What drug from the group of nonsteroid antiinflammatory drugs may be recommended this patient?
Celecoxib
Mefenamic acid
Indometacin
Aspirin
Diclofenac
181 із 200
An internship doctor prescribed his patient nifuroxazid from the group of ni-trofurans for the treatment of urinary tracts infection. The doctor made a mistake because:
It cannot be absorbed from the digestive tract
It is excreted with urine in the inactive state
It has nephrotoxic effect
It has bacteriostatic effect
It is excreted from the organism very slowly
182 із 200
Which of the following is the drug of choice for bronchial asthma attacks prevention?
Cromolyn sodium
Ambroxol
Diphenhydramine hydrochloride
Salbutamol
Drotaverine
183 із 200
A pharmaceutist needs to sterilize 250 ml of glucose solution for injections. How many minutes should the solution undergo sterilization in the autoclave under the temperature of 120°C?
12
8
30
15
25
184 із 200
Grinding equipment is classified by the way of grinding. What kind of machines does a roller crusher relate to?
Crushing
Impact-centrifugal
Cutting
Abrasive
Impact
185 із 200
Antacid gastritis can be treated with plantain juice. What is the way of its extraction?
High-pressure compression
Dissolution of concentrates
Extraction with condensed gases
Repercolation
Maceration with aqueous ethanol solution
186 із 200
Oxidation of some toxins within the body results in generation of compounds that increase their toxicity. Thus, due to the oxidation of heptachlor in the body the folowing compound is formed:
Heptachlor epoxide
Carbon monoxide
Heptachlor oxide
Hexachlorocyclohexane
Carbon dioxide
187 із 200
A pharmacy has sulfonamide biseptol on sale. What chemical compounds are the main components of this drug?
Sulfamethoxazole, trimethoprim
Phthalazolum, sulfadimezin
Urosulfan, sulfapiridazin
Sulgin, norsulfazol
Sulfazin, salazodimethoxinum
188 із 200
In course of isoniazid identification a pharmacy analyst boiled thoroughly the substance with 2,4-dinitrochlorobenzene. The substance turned yellow, after adding alkaline solution it turned first violet and then brownish-red. As a result of this reaction the following aldehyde derivative is produced:
Glutakon
Hexanic
Glyoxylic
Gluconic
Glutamic
189 із 200
A routine inventory revealed a cash shortage. Who must reimburse the sum of the identified shortage?
Cashier
Pharmacy director
Deputy director of pharmacy
Department head
Deputy head of Department
190 із 200
A pharmaceutical factory produces herbal juice out of fresh raw material. What operation should be performed at the stage of juice purification?
Heating followed by quick cooling
Filtration
Crystallization
Adsorption
Sedimentation
191 із 200
A patient suffering from stomach ulcer was prescribed an antiulcer drug that also reduces secretion of hydrochloric acid and inhibits Chelicobacter pylori. What drug is it?
Omeprazole
Gastrocepine
Famotidine
Maalox
Almagel
192 із 200
Quantitative determination of ni-trofural (furacilin) can be done by method of spectrophotometry. A pharmacy analyst can calculate quantity by measuring:
Optical density
Refractive index
pH of solution
Fusion temperature
Rotation angle
193 із 200
An edema can be relieved by means of hypertonic solutions. What phenomenon takes place in the blood cells after injection of such solution?
Plasmolysis
Lipolysis
Hemolysis
Hydrolysis
Electrolysis
194 із 200
A consulting pharmacist informed a patient about possible side effect of metronidazole that is normally provoked by alcohol intake. What is the mechanism of this phenomenon?
Enzyme alcohol dehydrogenase blocking
Enzyme glucose 6-phosphate dehydrogenase activation
Enzyme alcohol dehydrogenase activation
Enzyme acetylcholinesterase activation
Enzyme acetylcholinesterase blocking
195 із 200
An anaesthesiologist has to perform an operation under neuroleptanalgesia. Which of the following drug combinations should be used in this case?
Fentanyl with droperidol
Diazepam with aminazine
Fentanyl with diazepam
Droperidol with prednisolone
Promedol with amitriptillin
196 із 200
Common juniper is applied as a diuretic, anti-inflammatory and cholagogic agent. This plant gives the following medicinal raw material:
Fruits
Roots
Leaves
Seeds
Sprouts
197 із 200
Which of the following reagents should be added to the isoniazid to achieve blue colour and precipitation that turns light-green and emits gases when heated?
Copper sulfate solution
Silver nitrate solution
Iron (III) chloride solution
Alkaline solution
Hydrochloric acid solution
198 із 200
For accounting business transactions carried out in a pharmacy the synthetic accounts are used. Their list is given in the Chart of Accounts. Balances of the I, II and III account classes are used for completion of the following document:
Assets
Liabilities
Profit and Loss Account
First section of the liabilities balance sheet
Fourth section of the liabilities balance sheet
199 із 200
A 40-year-old patient suffers from bronchial asthma and cardiac rhythm disturbance in form of bradyarrhythmia. Drugs of which pharmacological group should be administered for bronchospasm suppression?
M-cholinergic antagonists
Cholinesterase inhibitors
M-cholinomimetics
Muscle relaxant
Beta-blockers
200 із 200
A patient who has taken phenobarbi-tal for a long time was prescribed diclofenac sodium. However the anti-inflammatory effect of diclofenac appeared to be less than expected due to the pharmacokinetic interaction of these drugs. Such interaction might be the result of the following processes:
Accelerated drug metabolism in liver
Decelerated drug metabolism in liver
Reduced protein concentration in plasma
Change of receptor sensibility
Increased drug dosage