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Step 2 - Pharmacy 2009
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During local anaesthetization novocai-ne solution is usually compounded with solution of adrenaline hydrochloride. What is the purpose of this action?
Vasoconstriction
Increase in smooth muscle tone
Algesthesia reduction
Vasodilatation
Decrease in smooth muscle tone
3 із 200
A 32-year-old patient takes antituberculous drugs. Some time later he has noticed that his urine turned orange. What preparation is the most likely cause of this phenomenon?
Rifampicin
Ethambutol
Pyrazinamide
Isoniazid
Streptomycin sulfate
4 із 200
6 months after treatment a patient with coronary heart disease developed tolerance to the nitrates with prolonged action. What drug with nitrate-similar effect should be recommended in this case?
Molsidomine
Prasosine
Nifedipine
Verapamil
Metoprolol
5 із 200
A 52-year-old patient was diagnosed with systemic amebiasis accompanied by bowels, liver and lungs affection. What preparation should be administered?
Metronidazole
Chingamin
Phthalazol
Chiniofon
Tetracycline
6 із 200
A 33-year-old woman who has been treated for chronic polyarthritis for a long time complains about arterial pressure rise, change of adipose tissue distribution, menstrual cycle disorder. What preparati- on has she taken?
Prednisolone
Synaflan
Butadion
Diclofenac sodium
Indometacin
7 із 200
A pharmaceutist made a tincture of althaea root. What is the proportion of herbal crude drug and extractant?
1:20
1:30
1:10
1:100
1:400
8 із 200
A pharmaceutical enterprise widely applies technical and technological media of information use in order to increase efficiency of managing productive and administrative activity of an organization, to enhance labour productivity, to improve methods of planning and regulating management processes. All this is realized by means of:
Automated management system
Information-management system
Automated instruction and control system
Automation equipped working place
Automated data retrieval system
9 із 200
Marketing research of certain pharmaceutical groups involves collection and analysis of primary information. This is the following type of marketing research:
Field research
Research of drug consumers
Armchair research
Research of marketing network of pharmaceutical market
Research of drug market
10 із 200
An analytical laboratory carries out quantitative analysis of sodium citrate by method of ionexchanging chromatography on a cationite. What titrated solution is to be used for the following titration of generated citric acid?
Sodium hydroxide
Iodine
Potassium iodate
Trilon B
Hydrochloric acid
11 із 200
A pharmaceutist prepared an oil emulsion containing zinc oxide. Specify the rational method of substance incorporation:
Suspension-type icorporation into the prepared emulsion
Dissolution in water for preparation of the primary emulsion
Dissolution in oil
Grinding with water for dilution of the primary emulsion
Dissolution in the finished emulsion
12 із 200
A pharmaceutist made a tincture of Adonis herb. A peculiarity of its preparation is that the active substances are derived in:
In the neutral medium
In the acid medium
In the alkalescent medium
In the subacid medium
In the alkaline medium
13 із 200
Preparations made of ginseng roots have tonic and adaptogenic properties, improve mental and physical performance. If the ginseng tincture cannot be found in a pharmacy, it can be substituted by the analogous preparations made of the following raw material:
Radices Eleutherococci
Radices Rhei
Radices Valerianae
Radices Ononidis
Radices Inulae
14 із 200
Balance is a part of financial accounting of pharmacies. What index is reflected in the assets of the balance sheet?
Residual value of fixed assets
Wholesale turnover
Proceeds of a pharmacy
Retail turnover
Salary costs
15 із 200
The market is characterized by the following conditions: a big number of salespersons and customers who don’t make any influence upon the level of current prices; availability of uniform and interchangeable competing products; lack of price restrictions. What type of market is it?
Market of pure competition
Market of monopolistic competition
-
Oligopolistic market
Market of pure monopoly
16 із 200
If the internal surface of buckthorn rind is moistened with 5% alkaline solution, it becomes cherry-red colouring. This is the evidence of presence of the following substance:
Anthracene derivatives
Alkaloids
Flavonoids
Tannins
Saponins
17 із 200
A pharmacy technologist received an ointment formulation: Rp.: Unguentum Resorcini 1,5% -10,0 Da. Signa. To be applied on the affected skin areas. The pharmaceutist incorporated dry medical substance into the ointment by the following way:
Trituration with a few drops of vaseline oil
Trituration with a few drops of water
Adding to the fused vaseline
Trituration with a part of vaseline
Trituration with a few drops of ethyl alcohol
18 із 200
A pharmacy analyst can verify presence of iron cation (II) in a drug formulation by means of the following solution:
Ammonium sulfide
Sodium phosphate
Sodium chloride
Potassium bromide
Magnesium sulfate
19 із 200
An advance holder (accountant) received money from the cash fund of an enterprise for purchase of office accessories. After the cash advance the advance holder must submit the statement of application of funds no later than:
On the next working day
There is no deadline
In three working days
In a week
In ten working days
20 із 200
Choose an antiseptic from the group of halogen containing drugs that can be included into the first-aid kit for a child going to a summer camp:
Alcoholic iodine solution
Formaldehyde solution
Copper sulfate solution
Methylene blue solution
Brilliant green solution
21 із 200
A pharmacy received a new-generation nonsteroid anti-inflammatory drug 'meloxicam'that mainly blocks cyclooxygenase-2. What advantages does this preparation have in comparison with other nonsteroid anti-inflammatory drugs?
Minimal side effect on alimentary tract
Interferonogenic properties
Evident myospasmolytic action
Significant inhibition of protease activity
Minimal side effect on hematogenesis
22 із 200
Leaves of belladonna, henbane and datura containing tropane alkaloids must be stored according to the following list requirements:
B list (these drug substances require caution in handling, storage or use)
Essential oil materials list
List of substances equivalent to narcotics
General sales list
A list (poisonous drug substances)
23 із 200
A patient suffering from essential hypertension has increased concentration of renin in blood plasma. Which pharmacological group should be preferred for this patient treatment?
ACE inhibitors
Sympatholytics
o-adrenoblockers
Diuretics
Blockers of calcium channels
24 із 200
A patient suffering from stomach ulcer was prescribed almagel. Which of its pharmacological properties is intended for treatment of this pathology?
HCl neutralization
Anti-inflammatory action
Blocking the H2-histamine receptors
Blocking the muscarinic choli-noreceptors
Local anaesthetization
25 із 200
One of the ways to derive essential oil is enfleurage, or maceration. Essential oil can be derived by enfleurage from the following herbal raw material:
Petals of Damascus rose
Mint leaves
Coriander fruits
Lemon skin
Camomile flowers
26 із 200
A pharmaceutist and a pharmacy manager were involved into the labour dispute about carry over of vacation time. The pharmaceutist applied to the council of conciliation. The council should consider his application within the following period:
10 days
3 days
1 week
1 month
5 days
27 із 200
All the medications require special storage conditions according to their physical and physicochemical properties. Ampouled solution of sodium adenosine triphosphate (ATP) should be stored under the following temperature:
3 - 5°C
10 oC
7 - 10oC
12 - 15oC
0 - 2°C
28 із 200
Quality control of tablets produced at a pharmaceutical enterprise involves quantitative determination of such subsidiary substances as talc and aerosil. What method is applied for such determination?
Gravimetric
Photocolorimetric
Chromatographic
Spectrophotometric
Titrimetric
29 із 200
A 52-year-old patient had myocardial infarction and was discharged from the hospital after the stationery treatment. What daily dose of acetylsalicylic acid should be administered in order to prevent thrombosis?
100 mg
500 mg
200 mg
1000 mg
50 mg
30 із 200
An analyst of a pharmaceutical storehouse received the substance of hydrogen peroxide for analysis. Quantitative determination of this drug should be performed by permanganatometric method. According to the analytical normative document, titration should be carried out till the solution turns:
Pink
Dark blue
Colourless
Green
Yellow
31 із 200
A patient suffering from ulcer disease was prescribed famotidine. What is the mechanism of its action?
Block of H2-histamine receptors
Block of muscarinic cholinoreceptors
Block of cholinoreceptors of sympathetic ganglions
Inhibition of adenosine triphosphatase activity
Block of H і-histamine receptors
32 із 200
Ophthalmic drops are produced on the base of concentrated riboflavin solution (1:5000). How much solution should be taken if the formulation says '0,001 of riboflavin'?
5 ml
3 ml
1 ml
2 ml
4 ml
33 із 200
While producing phytopreparations and organotherapeutic preparations different kinds of dryers are used. What dryer would be the most effective for drying thermolabile compounds?
Freeze-dryer
Band dryer
Roller dryer
Drum dryer
Drying oven
34 із 200
Choose an optimal antibacterial drug for the mycoplasmal pneumonia treatment:
Rovamycin
Gentamycin
Amoxyclav
Ampicillin
Penicillin
35 із 200
An analytical laboratory received substance of citric acid for the analysis. According to the requirements of the Ukrainian State Pharmacopoeia, citric acid can be determined by method of:
Alkalimetry
Acidimetry
Iodometry
Bromatometry
Iodochlorometry
36 із 200
According to the requirements of the Ukrainian State Pharmacopoeia, the amount of calcium gluconate can be determined by the chelatometric method. What solution should be used as a titrant?
Sodium edetate
Potassium permanganate
Hydrochloric acid
Iodine monochloride
Argentum nitrate
37 із 200
Tannins have astringent effect and are used for treatment of colitis, enterocolitis, diarrhea. What herbal raw material contains a lot of tannins?
Fructus Myrtilli
Fructus Rhamni catharticae
Fructus Frangulae
Fructus Ribes nigri
Fructus Sambucci nigri
38 із 200
Anthracene derivatives of emodi-ne group exhibit purgative effect. What herbal raw material contains large quantity of anthracene derivatives of emodine group?
Buckthorn fruits
Currants fruits
Alder buckthorn fruits
Elder fruits
Bilberry fruits
39 із 200
Codeine can be derived for medical purposes out of a plant alkaloid by means of semisynthetic method. Name this alkaloid:
Morphine
Papaverine
Berberine
Chelidonine
Protopine
40 із 200
Theory of management currently marks out four the most important approaches to the management. Choose the approach that is NOT USED in the theory of management:
Structural
Situational
Approach from the position of different schools identification
Process
Systemic
41 із 200
Therapeutic department of a municipal hospital purchases medical products in a pharmacy. The wares will be dispensed from the stores department on presentation of the following document:
Delivery order
Cash book
Register of laboratory packing works
Inventory report
Prescription register
42 із 200
In order to determine the purity a drop of lavender essential oil was applied on a strip of filter paper and warmed up in the stream of warm air. Some time later the stain increased in diameter. What impurity substance was found in the lavender oil?
Fatty or mineral oil
Diethyl ether
Phenol
Acetone
Ethanol
43 із 200
A doctor prescribed a patient 100 ml of tincture made out of 0,25 of Herba Thermopsidis. How much dried concentrated extract of Herba Thermopsidis should be weighed by a pharmaceutist?
0,25 g
0,1 g
0,3 g
0,5 g
0,2 g
44 із 200
A patient has ordered 50 g of zinc ointment. How much zinc and Vaseline should be weighed by a pharmaceutist?
5,0 g and 45,0 g
1,0 g and 49,0 g
0,5 g and 49,5 g
10,0 g and 40,0 g
2,5 g and 47,5 g
45 із 200
A patient got an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient has presented with red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucous membrane. What is the cause of this complication?
Immediate allergy
Local irritation
Delayed allergy
Abstinence syndrome
Tachyphylaxis
46 із 200
In Ukraine the out-patients are supplied with narcotic and psychotropic drugs only by prescription. Medicoprophylactic institutions receive prescription blanks (Form 3) from the following source:
Pharmacy storehouse
Typography
City’s health department
Wholesale companies
Pharmaceutical corporation
47 із 200
Injection solutions of salts derived from weak acids and strong bases require stabilization. What stabilizers are used for these solutions?
0,1 М solution of sodium hydroxide
Trilon B
0,1 М solution of perchloric acid
Buthylhydroxytoluene
Ascorbic acid
48 із 200
100 ml of 0,9% sodium chloride solution were prepared according to the doctor’s prescription. What sterilization schedule is required for this solution?
120oC - 8 minutes
120 oC -12 minutes
180 oC - 30 minutes
100 oC -15 minutes
120 oC -15 minutes
49 із 200
During digitoxin therapy for chronic cardiac insufficiency, a patient developed signs of intoxication with this preparation. The patient was prescribed unithiol. What is the mechanism of unithiol action in case of intoxication with cardiac glycosides?
Reduction of K+-Na+-adenosine triphosphatase
Increased potassium permeability in the cardiomyocytes
Binding of glycoside into the complex compound
Binding of calcium ions
Increase of sodium concentration in the cardiomyocytes
50 із 200
A pharmacy got a formulation of a mixture containing manzanita decoction and belladonna extract. What is the reason for incompatibility between these components?
Precipitation
Coagulation of colloid systems
Hydrolysis
Oxidation-reduction processes
Emission of gaseous substances
51 із 200
The central district pharmacy functions in a district centre and supplies local population with drugs and medical products. What pharmaceutical institutions are allowed to settle accounts with the customers without a cash register by way of check issuing?
Pharmacies, pharmaceutical outlets and kiosks
Pharmaceutical outlet at a hospital
Central district pharmacy
Pharmaceutical kiosk at a railway station
Pharmaceutical kiosk at a market
52 із 200
Method of gas-liquid chromatography is often applied for identification and quantitative determination of toxicologically meaningful substances. Substances can be placed into the chromatograph dispenser in the following aggregate states:
Liquid and gaseous
Gaseous
Liquid
Liquid and solid
Gaseous and solid
53 із 200
Examination of a patient who has been treated for rheumatoid arthritis for a long time revealed hyperglycemia. It might have been caused by the following drug:
Dexamethasone
Levamisole
Diclofenac sodium
Ibuprofen
Delagil
54 із 200
A pharmaceutist was preparing an ointment with ricin oil and Vaseline but failed to get homogenous system. What is the most likely cause of incompatibility between these components?
Component immiscibility
Release of water of crystallization
Coagulation
Adsorption
Restricted solubility
55 із 200
A large and well-known company has granted a small independent firm the right to use its trademark and technology so that it could take advantage of authori- ty and customer trust to the well-known brand. Such concept is called:
Franchising
Merchandising
Use of manufacturer’s brand
Use of trademark
Use of dealer’s brand
56 із 200
A woman who has been treated for infiltrative focal tuberculosis for a long time complains of acute hearing impairment. Which of the following preparations might be the cause of such side effect?
Streptomycin
Isoniazid
Rifampicin
Ethambutol
Ethionamide
57 із 200
A pharmaceutist revealed physical incompatibility caused by coagulation. This process takes place in a solution if the combination of the following substances is present:
Dimedrol and collargol
Dimedrol and novocaine
Dimedrol and glucose
Dimedrol and diazoline
Dimedrol and sodium chloride
58 із 200
A pharmaceutist made a medicinal preparation according to the following formulation: Rp.: Chloroformii Olei Helianthi Methylii salicylatis ana 10,0 M.D.S. For infriction. Specify the kind of disperse system:
Liniment - solution
Liniment - extractional
Liniment - combined
Liniment - emulsion
Liniment suspension
59 із 200
Aerosol composition includes active substances, solvents and propellents. Which of the following substances is used as propellent?
Freon-11, carbon oxide, propane-butane
Propylen glycol monostearate, argon, helium
Hydrogen sulfide, hydrogen, triethanolamine
Linethol, myristic acid, benzocaine
Isopropyl myristate, neon, sulfur oxide
60 із 200
A department producing sterile pharmaceutical forms needs a method of eye drops sterilization applicable for drugs derived from thermolabile substances. What is the optimal method of sterilization?
Sterile filtration
Filling in the inert gas medium
Use of polymeric packings
Thermal sterilization
Addition of ascorbic acid
61 із 200
Accounting of pharmaceutical institutions includes control accounts of nine classes. What accounting units are represented in the accounts of the 4-6 classes?
Liability
Element costs
Pharmacy assets
Incomings and business results
Material costs
62 із 200
A pharmaceutist revealed physical incompatibility in a recipe. Specify the combination of drug substances demonstrating eutectic when blended:
Camphor and menthol
Glucose and phenyl salicylate
Streptocid and antipyrine
Basic bismuth nitrate and magnesium oxide
Ascorbic acid and hydrocarbonate sodium
63 із 200
What drug may cause constipation in a patient undergoing combined therapy for arterial hypertension?
Verapamil
Acetylsalicilic acid in small dosages
Trimetazidine
Furosemide
Panangin
64 із 200
Management of a pharmaceutical company involves American and Japanese approaches. Choose a typical feature of American model of management:
Quick evaluation and career development
Slow career development
Heightened attention to the human factor
Group forms of control
Corporate liability
65 із 200
Quantitative analysis of drugs containing primary aromatic amine can be performed by means of nitritometric method. Which of the following preparations can be determined by the nitritometric method without preliminary acid hydrolysis?
Sulfadimine
Soluble streptocid
Phthazin
Paracetamol
Phthalazol
66 із 200
When filling the 'Inventory report', a pharmacy manager represented a number of business transactions in the receipts section of report. Such transactions include:
Purchase of drugs and pharmaceutical merchandise
Products consumption for business needs
Markdown on account of laboratory packing works
Total of realized trade mark-up
Total of sale
67 із 200
A patient suffering from neurosis accompanied by anxiety and fear development was prescribed diazepam. What pharmacological effect makes it possible to apply the drug for this disease treatment?
Anxiolytic
Anti-inflammatory
Antiarrhythmic
Antianginal
Hypotensive
68 із 200
A hospital admitted a child with signs of poisoning with belladonna alkaloids. What drug should be applied as an antidote?
Proserin
Magnesium sulfate
Paracetamol
Sodium caffeine benzoate
Sodium valproate
69 із 200
You are employed in a pharmaceutical storehouse. When adding newly received preparations to the computerized database, specify the pharmacological group of paracetamol:
Nonnarcotic analgetic
Antianginal drug
Hypnotic
Diuretic
Hypotensive drug
70 із 200
A 34-year-old patient suffering from bronchitis was prescribed an antitussive drug of central action. What drug is it?
Glaucine
Corglycon
Fercoven
Furosemide
Enalapril
71 із 200
Continuous taking of a drug results in reduction of its efficiency. This phenomenon is called:
Habituation
Sensibilization
Dependence
Cumulation
Tachyphylaxis
72 із 200
A patient was warned that taking the prescribed preparation might cause cough. What drug is it?
Lisinopril
Metoprolol
Phenihidine
Dichlothiazide
Clonidine
73 із 200
A pharmaceutist with over 8 years of service got a medical certificate in accordance with the established procedure. What is the size of temporary disability allowance the pharmaceutist is entitled to?
100% of average salary
80 % of average salary
50 % of average salary
90 % of average salary
60 % of average salary
74 із 200
A pharmacy functions on the base of collective financial liability. The financial liability agreement may be re-executed in the following case:
Dismissal of over 50% of staff
Employment of new employees
Dismissal of 10% of staff
Dismissal of 5% of staff
Dismissal of one staff member
75 із 200
A pharmacy sells drugs by retail. Omnopon relates to the following group of controlled drugs:
Narcotic
Psychtropic
General sale list
Potent
Toxic
76 із 200
A pharmaceutical company 'Pharmasvet'has patented and produces now a new hypoglycemic preparation. The company markets this product directly through the own marketing departments, affiliated marketing companies, pharmacy network. Marketing policy of this pharmaceutical company can be characterized by the channel of the following level:
Zero level
Three-level
One-level
Four-level
Two-level
77 із 200
A patient with acute cardiac insufficiency and cardiac glycoside intolerance got an injection of dobutamine. What is the mechanism of its action?
Stimulation of ^-adrenoreceptors
Stimulation of a1-adrenoreceptors
Stimulation of muscarinic choli-noreceptors
Inhibition of phosphodiesterase activity
Block of K+-, Na+-adenosine triphosphatase
78 із 200
A patient suffering from chronic cardiac insufficiency was prescribed a cardiac glycoside from the foxglove (Digitalis) group. What drug is it?
Digoxin
Cordiamin
Corvalol
Corglycon
Strophanthine
79 із 200
One of the methods of quantitative analysis of active substances in the raw material is the biological standardization. It can be applied with the following group of biologically active substances:
Cardiac gliycosides
Mucilages
Tannins
Alkaloids
Fatty oils
80 із 200
Lipophilic bases for suppositories include:
Mixtures of hydrogenatedd fats
Glycerol soap base
Gelatin-glycerol base
Collagen base
Polyethylene oxide base
81 із 200
An expert of an analytical laboratory is determining Nitrofural. What quanti- tative titrimetric method can be applied?
Iodometry
Nitritometry
Permanganatometry
Argentometry
Alkalimetry
82 із 200
A 52-year-old patient complains of having increased arterial pressure for a month. She has a 5year history of bronchial asthma. What group of hypotensive drugs should NOT be recommended this patient?
в-adrenoreceptor blockers
Diuretics
Tranquilizers
Calcium channel blockers
Angiotensin receptor blockers
83 із 200
A pharmacy analyst is determining one of the following drugs by the nintri-tometric method. What drug is it?
Norsulfazole
Analgin
Atropine sulfate
Ftivazide
Ammonium chloride
84 із 200
A chemotoxicological laboratory received a biological material. A toxicologist carries out uncontrollable analysis aimed at detection of the following group of toxic substances:
Volatile toxins
Mineral acids, alkali, inorganic salts
Medical use toxins
Pesticides
Metal toxins
85 із 200
Quality of injection solutions supplied in ampoules can be assessed according to different indices. How many ampoules should be checked while determining quality of sealing ( leaktightness of an ampoule)?
100%
80 %
50 %
75 %
97 %
86 із 200
A chemical department produces alcohol solution of boric acid. What filters are used for filtration of this solution?
Pressure filters
Nutsch filter
Bag filter
Paper filter
Membrane filter
87 із 200
An 18-year-old patient was diagnosed with disseminated pulmonary tuberculosis. What drug will provide etiotropic pharmacotherapy?
Isoniazid
Lincomycin
Benzylpenicillin sodium salt
Trimethoprim
Metronidazole
88 із 200
At the end of each month accountant of a pharmacy calculates amount of realized price markup. Which index IS NOT USED for such calculation?
Total of cash in vault
In-stock balance at the beginning of month in retail prices
In-stock balance at the beginning of month in wholesale prices
Total value of received goods in retail and wholesale prices
Total sales proceeds
89 із 200
Suspensions as heterogenous systems can be characterized by kinetic and sedimentary instability. What substance is used for increasing suspension stability with hydrophobic substances?
Gelatose
Boric acid
Sodium sulfate
Sodium chloride
Glucose
90 із 200
A pharmacy analyst is determining adrenaline tartrate by method of acid-base titration in the anhydrous solvents. What indicator is to be used according to the requirements of the Ukrainian State Pharmacopoeia?
Crystal violet
Eriochrome black
Phenolphthalein
Methyl orange
Thymolphthalein
91 із 200
A patient has accidentally taken a barium-containing salt. All of the following salts have toxic effect upon the human organism EXCEPT for:
Barium sulfate
Barium acetate
Barium chloride
Barium nitrate
Barium carbonate
92 із 200
A mineralizate under examination contains precipitates of barium sulfate and plumbum sulfate. These salts can be separated by means of:
Solution of ammonium acetate
Solution of sodium acetate
Solution of ammonium nitrate
Sulfuric acid
Acetic acid
93 із 200
A pharmaceutical company 'Adonis'promotes its new products by means of advertisement that informs the customers about the product, highlights its advantages, typical features and properties. What kind of advertisement is it?
Informational
Direct
Aggressive
Sustaining
Indirect
94 із 200
The founders are going to open a retail pharmacy. What way of business running is stipulated in this case?
Licence-based
Normative
Free
Limited
Without preliminary licencing or registration
95 із 200
While preparing decoctions in volume from 1000 to 3000 ml time of processing in boiling water bath should be:
40 minutes
25 minutes
45 minutes
30 minutes
15 minutes
96 із 200
A pharmacy analyst is measuring a drug by method of indirect bromatometry. Which of the following titrated solutions is to be used?
Sodium thiosulfate
Potassium bromate
Sodium edetate
Argentum nitrate
Sodium nitrite
97 із 200
An expert of an analytical laboratory is determining Ca2+ in the substance of calcium pantothenate. Specify the method of analysis:
Chelatometry
Iodometry
Permanganatometry
Nitritometry
Argentometry
98 із 200
Styles of maize with stigmata containing fatty acids, vitamins, essential oils, saponins and other substances are used as:
Diuretic and choleretic drug
Sedative and anticonvulsive drug
Cardiotonic and antiarrhythmic drug
Bactericidal and astringent drug
Expectorant and antitussive drug
99 із 200
Toxic substances can be isolated from the objects of biological origin by different methods. In case of poisoning with pesticides - derivatives of phosphoric acids -the following method is applied:
Infusion with organic solvents
Dialysis aout of alkalized solutions
Infusion with alkalized water
Infusion with water acidified with chloric acid
Distillation with water steam from the alkaline medium
100 із 200
Dispersion degree of drug substances is of great importance for the preparation of ophtalmic ointments. What drug substance should be thoroughly triturated with sterile vaseline oil before incorporating it into the pharmacopoeia-recommended ointment base?
Mercuric oxide yellow
Pilocarpine hydrochloride
Zinc sulfate
Ethyl morphine hydrochloride
Resorcin
101 із 200
Financial accountability of pharmacies consists of separate account forms. Which form presents accounts payable for the goods purchased?
Balance sheet, form 1
Balance assets, form 1
Financial performance report, form 2
Financial performance report, form 2m
Net worth statement, form 3
102 із 200
In Ukraine natural persons and small business entities are allowed to use the simplified tax system. What limit on the number of employees is established for such enterprises?
No more than 10 persons
No more than 30 persons
No more than 20 persons
No more than 40 persons
No more than 50 persons
103 із 200
Fatty oil containing saturated fatty acids is used for atherosclerosis prevention. Specify the medicinal plant that is used for oil production:
Flax seeds
Fennelflower seeds
Black chokeberry fruits
Dill seeds
Hawthorn fruits
104 із 200
A department of a pharmaceutical plant produces injection solutions. Ascorbic acid solution for injections relates to the following group of solutions:
Easily oxidized solutions
Solutions of substances that should be subjected to thermal sterilization
Solutions of salts derived from strong bases and weak acids
Solutions of salts derived from weak bases and strong acids
Solutions of substances requiring special rectification
105 із 200
A phytochemical department of a pharmaceutical factory produces biogenic stimulators out of different raw materials. Specify the plant-derived biogenic stimulators:
Liquid extract of aloe, aloe liniment, aloe juice, biosedum
Peloidinum, humisolum, torfotum, plasmol, solcoseryl
Peloidinum, humisolum, torfotum, Fibs pro injectionibus
Vitreous body, Suspesio Рlacetae pro injectionibus, aloe juice, biosedum
Liquid extract of aloe, peloidinum, biosedum juice
106 із 200
A pharmaceutist has prepared an ointment intended for application on the open wound surface. Such kind of ointment should meet the following additional requirement:
Sterility
Isotonicity
Isoionicity
Prolonged action
Isoviscosity
107 із 200
Powders represent an important group among the extemporal medicinal preparations. Which of the following components can be incorporated into a powder without preliminary grinding?
Basic bismuth nitrate
Calcium gluconate
Xeroform
Ascorbic acid
Camphor
108 із 200
Medications in the storing rooms of a medicoprophylactic institution should be placed on the shelves, in the cases, refrigerators or on the pallets or rickers. Toxic medications should be kept in:
In a locked metal case
In a wooden case
In the internal safe partition
In a safe
In a refrigerator
109 із 200
A storehouse received a batch of althaea roots. For its verification a drop of ammonia solution was applied upon the root section; the spot of section turned yellow. This is the evidence of presence of the following substance:
Mucilages
Pectins
Gum
Tannins
Vitamin C
110 із 200
According to the requirements of the Ukrainian State Pharmacopoeia, a pharmacy analyst is determining procaine hydrochloride by nitritometric method. What indicator should be used for this purpose?
Neutral red
Xylenol orange
Methyl red
Acid chrome blue
Crystal violet
111 із 200
According to the requirements of the Ukrainian State Pharmacopoeia, a pharmacy analyst is determining fluorouracil by method of nonaqueous titration. What titrated solution is to be used?
Tetrabutyl ammonium hydroxide
Potassium bromate
Ammonium thiocyanate
Sodium edetate
Sodium nitrite
112 із 200
According to the requirements of the Ukrainian State Pharmacopoeia, a pharmacy analyst is determining calcium gluconate by method of complexometric titration. What indicator is to be used?
Calconcarbon acid
Tropeolin 00
Methyl red
Crystal violet
Thymolphthalein
113 із 200
According to the requirements of the Ukrainian State Pharmacopoeia, a certain drug is being measured by method of chelatometric titration. What drug is it?
Calcium chloride
Potassium citrate
Potassium chloride
Sodium benzoate
Sodium thiosulfate
114 із 200
An analytical laboratory carries out an analysis of ferrum sulphate heptohydrate according to the requirements of the Ukrainian State Pharmacopoeia. The test portion of the substance should be titrated with the following solution:
Ammonium cerium sulfate
Sodium edetate
Argentum nitrate
Potassium bromate
Ammonium thiocyanate
115 із 200
A patient suffering from arterial hypertension and chronic bronchitis suddenly presented with dry cough and dyspnea. Body temperature remained unchanged. It is known that the patient takes captopril. These symptoms can be explained by increased generation of:
Bradyquinine
Angiotensin-1
Aldosterone
Natriuretic peptide
Renin
116 із 200
A man came to a pharmacy and asked to recommend him a drug for treatment of allergic rhinitis that occurs in the period of linden flowering. What drug may be applied?
Loratadine
Adrenaline
Losartan
Anapriline
Ambroxol
117 із 200
During the sensitifity test for benzylpenicillin a patient developed anaphylactic shock. The following preparation must be injected around the spot of antibiotic injection:
Adrenaline hydrochloride
Propranolol
Noradrenaline hydrotartrate
Atropine sulfate
Ceftriaxon
118 із 200
A pharmaceutist is preparing powders by the way of triturating one of the components with ethyl alcohol. Such technology of preparation is typical for the following substance:
Streptocid
Bolus alba
Starch
Zinc oxide
Talc
119 із 200
An accountant is calculating financial performance of a pharmacy. What item will be represented in the liabilities of the accountingreport791 called 'Operational result'?
Net profit (sales proceeds)
Profits tax
Cost of goods sold
Sales expenses
Administration expenses
120 із 200
The equity capital of a pharmacy is 7500 UAH, the liabilities make 2500 UAH. According to the formula of balance calculation given in the Statement of Standard Accounting Practice 2 the amount of pharmacy assets will be as follows:
10 000 UAH
7 500 UAH
4 000 UAH
12 000 UAH
2 500 UAH
121 із 200
Novocaine metabolism in the organism results in generation of p-amino-benzoic acid. What metabolic process underlies this conversion?
Hydrolysis
Oxidation
Conjugation
Reduction
Dealkylation
122 із 200
A patient got poisoned with nitrites. Nitrite detection by means of azo dye reaction involves using such acid:
Sulfanilic
Phosphoric
Sulfuric
Salicylic
Hydrochloric
123 із 200
Fruits of holy thistle (Silybum) are used for production of a number of domestic and foreign hepatoprotective drugs. Factor of merit of this raw material is content of:
Flavolignans
Terpenoids
Vitamins
Alkaloids
Cumarins
124 із 200
According to the pharmacopoeia requirements of liquid extract production, the extractant and the raw material should be taken in the following proportion:
1:1
1:10
1:4
1:3
1:5
125 із 200
A pharmacy got an order for powders containing ascorbic acid and sodium hydrocarbonate. What process takes place between the ingredients?
Dampening
Stratification
Oxidation
Adsorption
Precipitation
126 із 200
An analyst is measuring sodium benzoate in the anhydrous medium by the acidimetric method according to the requirements of the Ukrainian State Pharmacopoeia. What reagent had to be used as a solvent?
Anhydrous acetic acid
Pyridine
Water
Dimethyl formamide
Methanol
127 із 200
A pharmacy analyst is measuring mercury dichloride by method of indirect chelatometry. Excess of titrated solution of sodium edetate can be titrated by means of the following titrated solution:
Zinc sulfate
Sodium methylate
Potassium bromate
Sodium thiosulfate
Sodium hydroxide
128 із 200
Calcium lactate can be quantitatively determined by chelatometric method. According to the Ukrainian State Pharmacopoeia, the following substance should be used as indicator:
Calconcarbon acid
Tropeolin 00
Naphthol benzein
Diphenylcarbazone
Phenolphthalein
129 із 200
A pharmacy analyst of an analytical laboratory is studying procaine hydrochloride according to the requirements of the Ukrainian State Pharmacopoeia. What method is recommended by the Ukrainian State Pharmacopoeia for the quantitative analysis of this preparation?
Nitritometry
Alkalimetry
Acidimetry
Chelatometry
Bromatometry
130 із 200
A pharmacy got the following recipe: Rp.: Mucilaginis Amyli 50,0 Da. Signa. For the enema purposes. How much starch and distilled water did the pharmaceutist use in order to make this preparation?
1,0 g of starch; 49 ml of distilled water
2,0 g of starch; 48 ml of distilled water
10,0 g of starch; 40 ml of distilled water
1,0 g of starch; 50 ml of distilled water
5,0 g of starch; 45 ml of distilled water
131 із 200
Aerosol production involves usage of propellents relating to different groups. Choose the propellants that relate to the group of volatile organic solvents:
Methylene chloride, ethylene chloride
Carbon dioxide
Freons
Propane, butane, isobutane
Vinyl chloride and methyl chloride
132 із 200
Which preparation from the group of laxative agents IS NOT to be administered in case of intoxication with CNS-inhibiting substances?
Magnesium sulfate
Bisacodyl
Sodium sulfate
Vaseline oil
Guttalax
133 із 200
A patient with bronchial asthma was prescribed salbutamol that has led to relief of bronchospasm symptoms. This is associated with stimulation of:
в2-adrenoreceptors
^-adrenoreceptors
Muscarinic cholinoreceptors
Acetylcholine synthesis
134 із 200
A pharmacy analyst is going to take a part of his holiday in spring and a part in summer. Holiday dividing is allowed provided that its main part will be no less than:
14 days
10 days
16 days
12 days
18 days
135 із 200
TV periodically conducts campaigns for young people aimed at popularization of mechanical contraceptives (not indicating concrete trademarks). Such actions are a kind of the following marketing communication:
Publicity
Sale promotion
Sponsorship
Advertising
Personal sale
136 із 200
A biennial or perennial plant from the Apiaceae family has a blue-grey stem branching in its lower part. Its leaves are also blue-grey, finely dissected, with the ultimate filiform segments. The flowers are yellow, in compound umbels. Its fruit is used for production of 'dill water'. What plant is it?
Foeniculum vulgare
Conium maculatum
Coriandrum sativum
Petroselium crispum
Carum carvi
137 із 200
Water for injections is derived from the drinking or distilled water. It can be either used freshly made or stored under the required temperature conditions. Water for injections is produced in the following premises:
In a separate room of aseptic department
In the assistant room
In the sales area
In the prescription department
In the washing room
138 із 200
Department of finished drug products of the pharmacy №1 got a prescription for nasal drops 'Farmazolin'intended for a 2,8-year-old child. This drug will be dispensed at the following price:
At no cost
30 % of price
70 % of price
50 % of price
Full price
139 із 200
On the base of licorice root different drug dosage forms are produced, notably tablets, powders, syrups, teas. The only unused form is injection solution. Licorice roots exhibit haemolytic properties since they contain the following active substances:
Saponins
Polysaccharides
Essential oils
Alkaloids
Iridoids
140 із 200
A pharmaceutical factory produces camphor oil for topical application. What oil is to be used as a solvent?
Sunflower seed
Vaseline
Plum
Peach
Olive
141 із 200
A pharmaceutical enterprise produces ointments. What base is applied for production of sulfur ointment simple?
Emulsion
Vaseline
Lanolin
Base 'For ophthalmic ointments'
Polyethylene glycol
142 із 200
One of the accounting documents of a pharmacy is the balance sheet (Form 1) consisting of assets and liabilities. Name the elements of the asset of a pharmacy:
Circulating assets and non-current assets
Non-current and borrowed assets
Circulating assets and owned capital
Owned and borrowed assets
Circulating and borrowed assets
143 із 200
A 46-year-old patient suffering from chronic bronchitis came to a pharmacy. What expectorative drug may be recommended?
Ambroxol
Salbutamol
Libexin
Falimint
Glauvent
144 із 200
A 26-year-old pregnant woman (III trimester of pregnancy) complains about body temperature rise up to 39°C. What febrifuge may be recommended in this case?
Paracetamol
Analgin
Indometacin
Diclofenac
Aspirin
145 із 200
Forensic toxicological analysis is often done for the metabolism products of toxic substances. Amino benzophenones are generated during biotrasformation of:
1,4-benzodiazepines
Opiates
Phenothiazines
Butyrophenones
Barbiturates
146 із 200
A 48-year-old patient was given an intravenous injection of prednisolone in order to arrest a severe attack of bronchial asthma. Prednisolone relates to the following group of hormonal drugs:
Glucocorticoids
Gestagenic drugs
Anabolic steroids
Estrogens
Mineral corticoids
147 із 200
A patient who has been taking phenazepam for a month came to a pharmacy. He insisted on buying another two packs of this drug. According to the patient, he feels unwell without phenazepam. What is the mechanism of the developed side effect?
Drug dependence
Idiosyncrasy
Addiction
Cumulation
Aftereffect syndrome
148 із 200
A patient suffering from allergic rhinitis was prescribed ephedrine in form of nasal drops. The patient has significantly benefited from nasal instillation, and this stimulated him to use the drug every 2 hours. But under these conditions the drug appeared to be ineffective. What is the most likely cause of this phenomenon?
Tachyphylaxis
Cumulation
Idiosyncrasy
Drug dependence
Allergy
149 із 200
Adjuvant substances in the production of tablets give the tableted mass all necessary technological properties, ensure dosage precision, mechanical strength and stability of tablets during their storage. What adjuvant substances facilitate disintegration or solution of the tablets in the organism?
Disintegrants
Filling agents
Flavors
Lubricants
Antifriction agents
150 із 200
In case of loss of license a pharmaceutist should address an application for a duplicate to a licensing authority. The licensing authority is obliged to issue the duplicate to the applicant no later than in:
Three working days after application receipt
Two months after application receipt
The duplicate is not to be issued
Three months after application receipt
One month after application receipt
151 із 200
Determination of pH of a biological material by means of indicator paper is applied for the preliminary conclusion about substances that might have caused intoxication. The indicator paper moistened with plumbum acetate solution was exposed to the evaporations of the material under examination and turned black. This indicates that the material under examination contains:
Hydrogen sulfide
Carbonic gas
Carbon monoxide
Ammonia
Methane
152 із 200
Lapkina-Lazarenko method of ethylene glycol separation enables to isolate it effectively from the objects of chemotoxicological analysis. What is the selective transporter of ethylene glycol from the objects to the distillate?
Benzol
Water
Chloroform
Ethyl alcohol
Acetone
153 із 200
Tincture of what medicinal plant can be applied as a tonic?
Rhodiola rosea
Achillea millefolium
Orthosiphon stamineus
Digitalis purpurea
Robinia pseudacacia
154 із 200
Theobromine and theophylline can be determined by alkalimetric method according to the substituent. What acid is to be titrated with sodium hydroxide?
Nitric
Phosphoric
Chydrochloric
Sulfuric
Acetic
155 із 200
Calculate the quantity of dried belladonna extract (1:2) required for preparing the following drug formulation: Extracti Belladonnae 0,015 Magnesii oxydi 0,5 Natrii hydrocarbonatis 0,2 Misce ut fiat pulvis Da tales doses №10 Signa. 1 powder thrice a day.
0,3
0, 4
0, 6
0, 15
0,015
156 із 200
A 25-year-old patient has been taking antibiotics for 7 days. Antibiotic therapy has caused a complication in form of bowel dysbacteriosis. This complication should be treated with drugs of the following pharmacological group:
Probiotics
Antacids
Adaptogens
Cholagogic
Spasmolytics
157 із 200
A 57-year-old female patient was diagnosed with rheumatoid arthritis; she has also a history of stomach ulcer. What drug from the group of nonsteroid antiinflammatory drugs may be recommended this patient?
Celecoxib
Diclofenac
Aspirin
Indometacin
Mefenamic acid
158 із 200
Aerosol department of a pharmaceutical factory uses condensed gases in the capacity of propellants. Which of the following substances relates to the group of condensed gases?
Freon
Methylene chloride
Nitrous oxide
Ethylene chloride
Nitrogen
159 із 200
An internship doctor prescribed his patient nifuroxazid from the group of ni-trofurans for treatment of urinary tracts infection. The doctor made a mistake because:
It cannot be absorbed from the digestive tract
It is excreted from the orghanism very slowly
It is excreted with urine in the inactive state
It has nephrotoxic effect
It has bacteriostatic effect
160 із 200
A pharmaceutist is preparing an ointment under aseptic conditions on the sterile ointment base - composition of vaseline and lanoline with the ratio 6:4. The drug substance is incorporated by suspension type. Such technology of ointment preparation is typical for the following substance:
Benzylpenicillin sodium
Sodium sulfate
Sodium chloride
Thiamine chloride
Pilocarpine hydrochloride
161 із 200
A business entity carrying on the wholesale trade of drugs must be keepi- ng documents concerning purchase and sale for a certain period. Specify this period:
No less than three years
No less than two years
No less than ten years
No less than one year
No less than five years
162 із 200
This substance is of blue colour but unlike the colouring substances it doesn’t leave any stain. The powders prepared out of it are made according to the general rules. What substance is it?
Copper sulfate
Ethacridine lactate
Furacilin
Riboflavin
Acrichine
163 із 200
A pharmaceutist brews an aqueous extract out of medicinal raw material in the tightly closed infusion vessel for 15 minutes and stirs it without opening the lid. Such technology of infusion preparation is typical for the following medicinal raw material:
Mint leaves
Cowberry leaves
Manzanita leaves
Senna leaves
Bilberry leaves
164 із 200
A pharmaceutist made 10 powders containing atropine sulfate at a rate of 0,00005 pro dose. What trituration did he use?
1:100
1:50
1:1000
1:20
1:10
165 із 200
Public health services attach great importance to the drug quality, that’s why a pharmaceutic enterprise has concentrated its efforts upon the improvement of qualitative characteristics of its products. What concept of marketing management is applied in this company?
Product enhancement
Modern marketing
All the answers are correct
Production enhancement
All the answers are false
166 із 200
When a graduate becomes employed on a certain position he should be first familiarized with his rights and duties. What document regulates rights and duties of pharmacy employees?
Job description
All the answers are false
Labour code
Internal employment policies and procedures
All the answers are correct
167 із 200
In order to verify identity of tropan derivatives, Vitali’s reaction is applied. For that purpose the medications should be first decomposed with nitric acid and then treated with alcoholic solution of potassium hydroxide and acetone. What effect will be observed?
The solution will turn purple
Setting of white precipitate
The solution will turn green
Setting of black precipitate
Emission of gas bubbles
168 із 200
A patient suffering from epilepsy has taken Phenobarbital for a long time and developed drug tolerance. What is the mechanism of this phenomenon development?
Acceleration of biotransformation
Weakening of absorption
Accumulation of the drug in the organism
Inhibition of biotransformation
Increase of receptor sensibility
169 із 200
According to the applicable legislation of Ukraine, prices for some drugs and medical products are subject to governmental regulation. What is the maximal trade markup established for the drugs that are purchased by public and municipal institutions using budgetary funds?
10% of manufacturer’s wholesale price
30 % of manufacturer’s wholesale price
25 % of manufacturer’s wholesale price
15 % of manufacturer’s wholesale price
35 % of manufacturer’s wholesale price
170 із 200
A pharmacy sells drugs. What is the rate of value-added tax for drugs sold by a pharmacy?
0%
25 %
30 %
10 %
20 %
171 із 200
A pharmaceutical factory produces herbal juice out of fresh raw material. What operation should be performed at the stage of juice purification?
Heating with following quenching
Adsorption
Filtration
Crystallization
Settling
172 із 200
A phytochemical department of a pharmaceutical factory produces valerian tincture of fresh material. Technological peculiarity of its production is that it should be produced on the base of:
70% ethanol with the ratio 1:5
70 % ethanol with the ratio 1:10
90 % ethanol with the ratio 1:5
95 % ethanol with the ratio 1:10
90 % ethanol with the ratio 1:10
173 із 200
A patient suffering from stomach ulcer was prescribed an antiulcer drug that also reduces secretion of hydrochloric acid and inhibits Chelicobacter pylori. What drug is it?
Omeprazole
Gastrocepine
Famotidine
Maalox
Almagel
174 із 200
Quantitative determination of ni-trofural (furacilin) can be done by method of spectrophotometry. A pharmacy analyst can calculate quantity by measuring:
Optical density
Rotation angle
pH of solution
Fusion temperature
Refractive index
175 із 200
Inventory in a pharmacy revealed a shortage within the range of natural loss. This shortage will be rated as expenses at the following price:
Wholesale
Procurement
Contract
Negotiated
Retail
176 із 200
What substance will impede reaction of iodoform test aimed at detection of ethyl alcohol in the biological material?
Acetone
Formaldehyde
Methanol
Phenol
Isoamyl alcohol
177 із 200
On the wage of pharmacy employees the personal income tax is levied. What pays ARE NOT INCLUDED into the total monthly income being subject to this kind of taxation?
Maternity pay
Sick care benefit
Income in kind
Sick leave benefit
Dividends
178 із 200
Analgin substance was sent for analysis. What method allows to evaluate quantitative content of analgin?
Iodometry
Alkalimetry
Acidimetry
Chelatometry
Permanganatometry
179 із 200
A pharmaceutist prepares internal drops with the following formulation: 5 ml of adoniside, 10 ml of valerian and lily-of-the-valley tincture each, 0,1 g of menthol, 2,0 g of potassium bromide. It will be efficient to dissolve potassium bromide in the following substance:
In the adoniside
In the lily-of-the-valley tincture
In the mixture of tinctures
In the valerian tincture
Potassium bromide should be added into the selling vial last of all
180 із 200
A pharmacy technologist revealed incompatibility of a formulation: Rp.: Mentholi 0,5 Natrii hydrocarbonatis Natrii tetraboratis aa 1,5 Aquae purificatae 100 ml M.D.S. 1 tablespoon twice a day. What action should the pharmaceutist take in order to make this pharmaceutical form?
Add stabilizer
Substitute one of the components
Change pharmaceutical form
Substitute the solvent
Perform fractional dissolution
181 із 200
A pharmaceutist is preparing vaginal suppositories by method of pouring. Which hydrophilic base can he use for this purpose?
Polyethylene oxide
Cocoa butter
Vitepsol
Butyrol
Hard fat
182 із 200
A patient with arterial hypertension was administered a non-prescription drug for symptomatic treatment of rhinitis. What pharmaceutical form should be recommended the patient in order to reduce as much as possible the likelihood of development of undesirable systemic vasoconstriction?
Ointment
Tablets
Gel
Drops
Aerosol
183 із 200
A 56-year-old patient suffering from essential hypertension was prescribed an inhibitor of angiotensin converting enzyme (ACE) and a potassium-sparing diuretic. Such combination is:
Unreasonable because it increases risk of hyperkaliemia development
Reasonable because it decreases risk of hyperkaliemia development
Reasonable because it potentiates hypotensive effect of ACE inhibitor
Unreasonable because it reduces hypotensive effect of ACE inhibitor
Unreasonable because it increases risk of orthostatic collapse development
184 із 200
Treatment course of essential hypertension includes diuretics. Which diuretic DOES NOT NEED to be combined with potassium preparations?
Triamteren
Dichlothiazide
Furosemide
Clopamide
Ethacrynic acid
185 із 200
Restharrow (Ononis) root is used for production of a tincture for treating haemorrhoidal haemorrhages. Isoflavonoids can be identified in the raw material by means of:
Chromatographic method
Hemolytic index
Foam index test
Biological standardization
Cyanidin test
186 із 200
Hawthorn flowers are used for production of cardiotonic drugs. During procurement of this crude drug the flowers of the following plant can appear in it:
Blackthorn
Buckthorn
Elder
Brier
Bird cherry
187 із 200
A pharmacy store was supplied with 100 packs of a product listed as Nitroglycerine. With regard to its physicochemical properties this preparation should be rated among the following drug group?
Explosive substances
Combustible substances
Explosion hazardous substances
Volatile substances
Highly inflammable substances
188 із 200
An edema can be relieved by means of hypertonic solutions. What phenomenon takes place in the blood cells after injection of such solution?
Plasmolysis
Hemolysis
Lipolysis
Hydrolysis
Electrolysis
189 із 200
During an operation a dentist needs to reduce salivation in a patient. The dentist has to use a drug of the following pharmacological group:
Muscarinic receptor blockers
Muscarinic and nicotinic cholinomi-metics
Adrenomimetics
Muscarinic cholinomimetics
Adrenoceptor blocker
190 із 200
Product assortment is the whole set of product assortment groups offered by an enterprise. The index representing number of positions in each product assortment group is called:
Product assortment depth
Assortment comparability
Product assortment saturation
Product assortment width
Product assortment
191 із 200
A pharmacy analyst of the laboratory at the National drug quality control inspection is conducting quantitative determination of caffeine by method of acid-base titration in the anhydrous solvents according to the requirements of National Pharmacopeia of Ukraine. What titrated solution is to be used?
Perchloric acid
Sodium hydroxide
Potassium bromate
Sodium edetate
Sodium methylate
192 із 200
Common juniper is applied as a diuretic, anti-inflammatory and cholagogic agent. This plant gives the following medicinal raw material:
Fruits
Seeds
Leaves
Sprouts
Roots
193 із 200
Functioning of a pharmacy is realized on different levels of management. Function of direct control of employees fulfilling concrete tasks relates to the following level of management:
Technical
Managerial
Institutional
Administrative
Bureaucratic
194 із 200
Pharmaceutical chemistry studies methods of drug synthesis. Interaction of anesthesin with beta-diethylaminoethanol in presence of sodium alcoholate with following acidation with hydrochloric acid results in origination of:
Procaine hydrochloride
Trimecaine hydrochloride
Tetracaine hydrochloride
Procainamide hydrochloride
Xycain
195 із 200
After a sulfamide preparation was heated with salicylic acid in presence of concentrated sulfuric acid, it turned crimson. What drug is analyzed?
Sulfaguine
Streptocid
Soluble streptocid
Ethazol
Phtalazol
196 із 200
A pharmacy procured common origanum. What drying conditions should be applied for producing high quality crude drug?
35 - 40oC
50 - 60oC
80 - 90oC
70 - 80oC
60 - 70oC
197 із 200
A 67-year-old patient who undergoes treatment for bronchial asthma presents with limb tremor, headache, insomnia, extrasystole. What drug might have caused such symptoms?
Theophylline
Acetylcysteine
Tavegyl
Prednisolone
Intal
198 із 200
For accounting business transactions carried out in a pharmacy the synthetic accounts are used. Their list is given in the Chart of Accounts. Balances of the I, II and III account classes are used for completion of the following document:
Assets
Fourth section of the liabilities balance sheet
First section of the liabilities balance sheet
Liabilities
Profit and Loss Account
199 із 200
A 40-year-old patient suffers from bronchial asthma and cardiac rhythm disturbance in form of bradyarrhythmia. Drugs of which pharmacological group should be administered for bronchospasm elimination?
Muscarinic receptor blockers
Anticholinesterase drugs
Muscle relaxants
Muscarinic cholinomimetics
Beta-adrenoceptor blockers
200 із 200
A patient who has taken phenobarbi-tal for a long time was prescribed diclofenac sodium. However the anti-inflammatory effect of diclofenac appeared to be less than expected due to the pharmacokinetic interaction of these drugs. Such interaction might be the result of the following processes:
Accelerated drug metabolism in liver
Change of receptor sensibility
Increased drug dosage
Reduced protein concentration in plasma
Decelerated drug metabolism in liver