A research group is investigating a complex of three enzymes. They have created cultures of myocytes derived from high-performance college athletes and simulated starvation conditions. After the experiment they concluded that during starvation the amount of this complex in the muscle tissue was higher. The complex converts pyruvate into acetyl-coenzyme A which enters the citric acid cycle (Krebs cycle) under aerobic conditions. This reaction also involves the further reduction of NAD⁺ molecules into NADH. An activating effect of which of the following enzymes is described above?

Lactate dehydrogenase
Phosphorylase
Hexokinase
Phosphofructokinase
Pyruvate dehydrogenase