Step 2 - Pharmacy 2013

It is required to prove the presence of bismuth ions in the mineral residue. What preliminary reaction is used for this purpose?

With dithizone

With 8-hydroxyquinoline

With potassium chromate

With copper acetate

With sodium rhodizonate

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A pharmacy prepared a solution of macromolecular substance with limited swelling capacity. What solution was labelled 'warm up before use'?

Methyl cellulose

Pepsin

Trypsin

Gelatin

Pancreatin

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A pharmacy rceived a prescription for ethyl alcohol. What amount of alcohol can be dispensed to the patient with diabetes free of charge?

150 g per month

200 g per month

50 g per month

There is no standard

100 g per month

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Schedule of sanitation actions in pharmacies is regulated by the relevant regulatory acts. Cleaning day at a pharmacy must be scheduled for at least 1 time:

In 5 days

In 3 days

In a week

In 10 days

In a month

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6 months after treatment a patient with coronary heart disease developed tolerance to the prolonged-action nitrates. What drug with nitrate-similar effect should be recommended in this case?

Prazosin

Molsidomine

Nifedipine

Verapamil

Metoprolol

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Losartan for treatment of arterial hypertension is contraindicated in case of:

Hypokalemia

Pregnancy

Urine acid diathesis

Hyperlipidemia

Hyperglycemia

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A patient with hypertensive crisis has been given an intravenous injection of clonidine. What mechanism underlies the antihypertensive effect of clonidine?

Direct myotropic effect on blood vessels

Blockade of peripheral a-adrenergic receptors

Stimulation of the central presynaptic a2-adrenergic receptors

Blockade of в-adrenergic receptors

Blockade of N-cholinergic receptors

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A patient with the symptoms of cardiac glycoside intoxication has been administered unitiol. What is the mechanism of therapeutic action of this drug?

Increased penetration of K + into the cardiac myocytes

Increase in Na+ level in the myocardium

Binding of the ionized Ca2+

Reactivation of the membrane K +, Na+-ATPase

Induction of cardiac glycosides metabolism

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A 38-year-old male patient with mercuric chloride intoxication has been delivered to the admission ward in grave condition. What antidote must be immediately administered the patient?

Nalorphine

Dipyroxime

Atropine

Unithiol

Izonitrozinum

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Standard herbal material of lily-of-the-valley is obtained by drying it at a temperature of 50-60 oC in order to prevent the following possible biochemical process :

Oxidation of phenolic compounds

Oxidation of resins

Enzymatic hydrolysis of cardiac glycosides

Oxidation of terpenoids

Volatilization of essential oils

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Which drug including the beta-lactam cycle in its structure gives a positive reaction with a solution of hydroxylamine hydrochloride in the presence of sodium hydroxide followed by adding the solution of iron (III) chloride?

Streptocid

Papaverine hydrochloride

Phenoxymethylpenicillin

Dibazolum

Antipyrine

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A pharmaceutical plant produces spi-ssum extract with 0,25% ammonia solution used as an extractant. This is a spissum extract of:

Sagebrush

Licorice

Valerian

Motherwort

Male fern

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A person got poisoned with the lead compounds. What is the most sensitive method of the quantitative analysis of lead ions?

Gravimetry

Photometry

Dichromate iodimetry

Atomic absorption spectrometry

Chelatometry

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A marketing manager of a pharmaceutical company carries out market research on vitamin preparation market. He takes into account various parameters including the therapeutical effectiveness, supply and demand. What method should be applied?

Graph method

-

Delphi method

Mathematical statistics method

Method of extraction from the original medical records

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A factrory workshop producing suspensions and emulsions is going to develop the manufacture of new drugs. What mechanisms can be used for the ultrasound processing of drugs?

Centrifugal mixer with rotating housing

Dismembrator, electrical impulse plasmolyzer

Liquid whistle, magnetostrictive source

Rotor-pulsation apparatus, di-smembrator

Disintegrator, liquid whistle

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A pharmaceutist prepared a lipophilic ointment of suspension type. What substance is used for preparing this kind of ointments?

Herbal extracts

Protargolum

Menthol

Tannin

Xeroform

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A pharmaceutist has a labour dispute with the pharmacy administration about rescheduling his annual vacation leave. The employee can appeal against the decision of the pharmacy administration to the following body:

Commercial court

Labour disputes commission (LDC)

MoH of Ukraine

Trade union committee

Highest management bodies of pharmaceutical service at the regional level

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Medications Passit and Novopassit are used as tranquilizing, sedative and mild hypnotic agents. These medications are produced from the following grass:

Garden sage

Purple passionflower

Lesser periwinkle

Elecampane

Three-lobe beggarticks

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During transportation, the markings on the packages of theobromine and theophylline were damaged. What solution allows to identify theobromine and theophylline?

Cobalt chloride

Sodium chloride

Potassium dichromate

Potassium permanganate

Copper nitrate

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Which of the following antihypertensive drugs has potassium-sparing action?

Furosemide

Triamterene

Diltiazem

Prazosin

Metoprolol

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What drug acts as a specific antidote in case of iron drug intoxication?

Atropine

Penicillamine

Protamine sulfate

Deferoxamine

Bemegride

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A regional medical representative of a foreign company uses the data derived from periodicals and reference and statistical materials in order to characterize the territorial pharmaceutical market. What kind of market research is based upon these sources?

Field studies

This method does not apply to research

-

All answers are correct

Desk studies

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A pharmaceutist was on a business trip. What is the deadline for submitting a travel expense report?

A week after returning from a trip

Ten working days after returning from a trip

Three working days after returning from a trip

Four working days after returning from a trip

There is no deadline

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An accountable person (accountant) has been given some cash from the cash account of the company for the purchase of stationery goods . What is the deadline for submitting a full statement of the accountable person on the cash use after receiving the cash?

There is no fixed term

Five working days

Ten working days

Third banking day

One week

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A pharmaceutist prepares trituration of atropine sulfate. What adjuvant should be used for this purpose?

Saccharose

Lactose

Starch

Glucose

Talc

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A pharmaceutical factory produces tablets of sodium chloride. What is the method of their poduction?

Wet granulation prior to compression

Dry granulation prior to compression

Direct compression with the addition of excipients

Moulding

Direct compression without additional substances

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A pharmaceutical factory produces suspensions and emulsions. Specify the equipment which is used for dispersion and mixing in the liquid medium:

Gate mixers

Drum mixers

Rotor-pulsation apparatus, colloid mixers

Oscillating mixers

Anchor mixers

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A pharmaceutist prepared eye drops containing silver nitrate. What substance must be taken to ensure isotonicity?

Sodium chloride

Glucose

Boric acid

Sodium sulfate

Sodium nitrate

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In order to detect the presence of thiosulfate ions a pharmaceutical analyst added the excess reagent. The resulting reaction produced a white precipitate, which slowly turned yellow, then brown, and black. What solution was added?

Diphenylamine

Ammonium oxalate

Barium chloride

Silver nitrate

Lead (II) acetate

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Collective labour agreement is concluded by a trade union committee with the enterprise owner on behalf of the workforce. Any collective agreement is worked out in written form. Which article of the Labor Code regulates the duration of the collective agreement?

17

38

36

40

41

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A person got poisoned with salts of manganese. Analysis of the mineral residue revealed manganese ions. What reactions underlie the chemical processes of manganese detection?

Dissociation

Hydrolysis

Oxidation-reduction

Metathesis

Neutralization

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A pharmaceutist prepares a solution for injections that must be stabilized with 0,1M of hydrochloric acid solution. What solution is to be prepared?

Sodium benzoate

Novocaine

Hexamethylenetetramine

Potassium chloride

Calcium chloride

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Paracetamol substance has been sent for analysis. Reaction with the solution of iron (III) chloride gave the blue-purple colour. This indicates the presence of:

Alcoholic hydroxyl

Aldehyde group

Keto group

Phenolic hydroxyl

Ester group

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Production of tablets requires stage-to-stage quality control. What devices are used to determine the particle size distribution (fraction) of granules?

Various vibrosieves

Laboratory IDs

Microscope

Standard set of sieves

Friabilators

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Analysis of the drug sales performance revealed market expansion, the absolute increase of the drug in manufacturer’s stocks, slowdown in the growth rate of sales, intense competition. What stage of the product life cycle is the drug in?

Maturity

Development

Saturation and decline

Growth

Introduction

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Anthracene derivatives of emodin have purgative effect. Large quantities of anthracenederived groups of emodin are contained in the fruits of the following plant:

Blueberry (Vaccinium myrtillus)

Blackcurrant

Buckthorn

Elder (Sambucus)

Alder buckthorn (Frangula alnus)

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Theory of management currently points out four the most important approaches to the management. Select the approach that is NOT applied in the theory of management:

Structured

Situational

Different schools dedication approach

Process approach

Systemic

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A pharmaceutist worked on a holiday, and the time worked was within the normal working hours of the current month. The employee would be entitled to be paid:

Single piecework rate

There would be no penalty rates

Fixed salary + double daily rate

According to the standard procedure as for a normal working day

Fixed salary + one daily rate

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A pharmacy has a license for selling narcotic drugs. The warrant for the receipt of these drugs from the pharmacy warehouse is valid for:

No longer than one calendar days from the date of issue

No longer than one year from the date of issue

No longer than 10 calendar days from the date of issue

No longer than five calendar days from the date of issue

No longer than three months from the date of issue

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Help the doctor to select a drug for the replacement therapy after the thyroid gland removal:

Mercazolilum

L-thyroxine

Prednisolone

Parathyroidin

Insulin

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Chloride of lime is identified by calcium cations after boiling with acetic acid in order to eliminate active chlorine. What reagent is used?

Magnesium sulfate

Potassium chloride

Ammonium oxalate

Sodium nitrite

Ammonium molybdate

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The medicine 'Bismuthi subnitras'can be identified after dissolving it in the acid with the following reagent:

Potassium iodide

Potassium nitrate

Sodium sulfate

Potassium chlorate

Sodium chloride

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Sterilization methods used for the preparation of drugs under aseptic conditions can be differentiated into physical, mechanical, and chemical ones. Specify the chemical method of sterilization:

Dry heat sterilization

Pressure steam sterilization

UV light sterilization

Radiation sterilization

Addition of preservatives

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Activity of a company leader involves managerial decision-making aimed at the achievement of corporate goals. Which of the following decisions are NOT classified by the method of justification?

Intuitive

Rational

Standard

Decisions based upon judgements

-

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Pharmacies prepare triturations of toxic and superpotent substances. They can be prepared in a following ratio:

1:500

1:1000

1:10 only

1:10 and 1:100

1:100 only

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It is required to prepare furacilin solution (1:5000). What is the dissolution peculiarity of furacilin?

It dissolves in the boiling water purified in the presence of sodium chloride

It dissolves in the filtered purified water

It dissolves in the purified water after the trituration

It dissolves in a minimal amount of ethyl alcohol

It dissolves in the cold purified water

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The method of suspension preparation depends on the properties of its components. Specify the substances having hydrophobic properties:

Boric acid, calcium carbonate

White clay, bentonite

Sodium bicarbonate, sodium sulfate

Zinc oxide, talc

Camphor, menthol

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A patient has been prescribed hand-rolled rectal suppositories with 0,1 g of aminophylline. What is the amount of base required for each suppository, provided that the suppository weight is not specified in the formulation?

2,4 g

3,9 g

2,9 g

1,4 g

1,9 g

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Pharmaceutical depot received a batch of herbal material of cinnamon rose. What substance determines the quality of the raw material?

Tannins

Anthracene derivatives

Ascorbic acid

Coumarins

Essential oil

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A pharmaceutist prepares an ointment on a hydrophobic base. What substance does he use in order to reduce the melting point of the base?

Vaseline oil

PEG-40

Glycerol

Ethanol

Dimexide

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In order to identify deoxycorticosterone acetate a pharmaceutical analyst performed a steroid cycle reaction, which resulted in formation of cherry-red colour and a green fluorescence. What reagent was added?

Chloroform

Potassium hydroxide solution

Iodine solution

Iron (III) chloride solution

Concentrated sulfuric acid

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An analytical laboratory received a sample of alpha-aminobutyric acid for analysis. What reagent should be used by the analyst in order to identify this substance?

Calcium bromide

Sodium nitrate

Aniline

Benzene

Ninhydrin

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A retail pharmacy has been purchasing goods within an accounting period. What changes to the balance will result from this business transaction?

Changes will be caused to the assets only

Increase in assets and liabilities

-

Decrease in assets and liabilities

Changes will be caused to the liabilities only

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Leaves of greater plantain are harvested in summer by mowing or cutting them with a knife or a sickle. There is always one developed plant left per 1 m2. The plant is harvested in the following vegetation period:

Rosetting

Blooming

Beginning of fruiting

Budding

Ripeness

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A manufacturing enterprise plans to sell a new drug through the corporate chain of pharmacies. What strategy of drug distribution would be used?

Direct

Multi-echelon

Vertical integration

Horizontal integration

Flexible

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The quality of tablets is assessed by various factors. What instrument is used for the tablet disintegration test?

Basket apparatus

-

Flow-through device

Friabilator

Paddle

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A pharmaceutical manufacturer develops a system of product. The focus is laid on the maximum involvement of agent network. What type of marketing is applied?

-

Combined

Exclusive

Selective

Intense

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While preparing marshmallow root extract, a pharmaceutist mistakenly used the water of improper temperature for this extract, and the end product came up turbid. What is the required water temperature for the extraction of this herbal material?

40 oC

100 oC

80 oC

60 oC

Room temperature

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A 67-year-old patient with chronic heart failure takes digoxin. In order to reduce its side effects the patient’s doctor recommended to combine it with the followig drug:

Euphyllinum

Calcium chloride

Hydrochlorthiazide

Calcium gluconate

Panangin

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A certain plant is used for production of tinctures and extracts which are the part of complex drugs Bellataminal, Becarbon, Besalol, etc. Specify the grass that is used for this purpose:

Belladonna

Beggarticks

Celandine

Lily of the valley

Astragalus

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A woman who has been treated for infiltrative focal tuberculosis for a long time complains of acute hearing impairment. Which of the following preparations might be the cause of this side effect?

Streptomycin

Ethambutol

Isoniazid

Rifampicin

Ethionamidum

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A pharmaceutist prepared a drug by the prescription: Rp.: Streptocidi Dermatoli ana 1,0 Lanolini Vaselini ana 5,0 M.D.S.: Apply to the affected skin. Specify the type of the disperse system:

Hydrophilic ointment

Suspension ointment

Combined ointment

Solution ointment

Extraction ointment

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Which of the following antibiotics can be identified by means of the maltol test?

Lincomycin hydrochloride

Kanamycin monosulfate

Amoxicillin

Doxycycline hydrochloride

Streptomycin sulfate

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Pharmacies as legal entities must have statutory capital in order to get registered with state authorities. Specify the amount which is identified as the statutory capital:

Total sources of funds

Total assets

Amount of noncurrent assets

Amount recorded in the constituent documents

Outstanding amount

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A pharmaceutist prepared 100,0 g of oil emulsion using 5% solution of methyl cellulose as an emulsifier. Specify the required amount of oil and emulsifier for the drug preparation:

20,0 g, 30,0 g

20,0 g,10,0g

10,0 g, 30,0 g

10,0 g, 10,0 g

10,0 g, 20,0 g

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A pharmaceutist prepared the 2% aqueous solution by dissolving the drug substance triturated in a mortar. What substance is this technology typical for?

Potassium bromide

Osarsolum

Boric acid

Calcium gluconate

Potassium permanganate

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A pharmaceutist prepares powders with papaverine hydrochloride. What hand scales should be used for weighing out 0,05 g of substance?

BP 5,0

BP 20,0

BP 2,0

BP 1,0

BP 10,0

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What drug can be recommended for symptomatic treatment of muscle pain in a 5-year-old child?

Diclofenac sodium

Indomethacin

Celecoxib

Acetylsalicylic acid

Paracetamol

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A pharmacy received a prescription for an oil liniment including streptocidum. What is the type of disperse system of this preparation?

Emulsion

Combined

Alloy

Solution

Suspension

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White precipitate produced by the reaction of morphine hydrochloride with ammonia solution dissolves in sodium hydroxide solution due to the presence of the following group in the structure of morphine hydrochloride:

Aldehyde group

Phenolic hydroxyl

Carboxyl group

Keto group

Alcoholic hydroxyl

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A person got poisoned with alcohols. What alcohol derivatives are used for the analysis by gasliquid chromatography?

Alkyl nitrates

Alkyl sulfites

Alkyl sulfates

Alkyl nitrites

Alkyl acetates

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A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the substance?

Tartaric acid

Zinc oxide

Potassium permanganate

Iron (III) chloride

Sodium hydroxide

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According to SPhU, formaldehyde can be identified when a sample is reacted with chromotropic acid solution in the presence of concentrated sulfuric acid. What colour is formed by this reaction?

Green

Blue

Yellow

Violet

Brown

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Stimulation of beta-cells of the pancreas causes the hypoglycemic effect of the following drug:

Retabolilum

Prednisolone

Heparin

Glibenclamide

Adrenaline hydrochloride

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A patient with Parkinson’s disease has been prescribed a drug with a predominant effect on the dopaminergic system. What drug is it?

Zopiclone

Aminazine

Droperidol

Levodopa

Lorazepam

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Exacerbation of urolithiasis has caused a renal colic in the patient. What drug must be administered to arrest the colic?

Neostigmine methylsulfate

Drotaverine hydrochloride

Almagel

Aethimizolum

Siliborum

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A patient with atopic dermatitis presented to the hospital. Which drug with anti-inflammatory and antiallergic effect should be administered to this patient?

Retabolilum

Oxytocin

Prednisolone

Aethamidum

Insulin

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What solution is used for the detection of iron (II) ions under the SPhU requirements?

Lanthanum nitrate

Sodium hydroxide

Potassium ferricyanide

Silver nitrate

Ammonia

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The manufacturing pharmaceutical company Elema set up its own corporate pharmacy. In this case, it uses the following distribution channel:

Fourth level

Zero level

Second level

Third level

First level

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An analytical laboratory has the task to confirm the presence of ethylenedi-amine in the aminophylline. Which of the following reagents alows to detect ethylenediamine?

Copper (II) sulfate

Sodium hydroxide

Barium chloride

Concentrated sulfuric acid

Silver nitrate

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Help the doctor to select a drug from the group of non-steroidal antiinflammatory drugs, which is an inhibitor of COX-2 and does not damage the stomach:

Indomethacin

Acetylsalicylic acid

Celecoxib

Diclofenac sodium

Paracetamol

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A patient with acute intoxication has been administered a loop diuretic in order to cause the forced diuresis. What drug is it?

Hydrochlorothiazide

Furosemide

Spironolactone

Mannitol

Triamterene

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A hypertensive patient has been administered lisinopril. What side effect is typical for this drug?

Increased appetite

Vomiting

Constipation

Insomnia

Dry cough

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Advise an internship doctor on why iron preparations should not be administered along with antacids:

This accelerates elimination of iron preparations

This increases intoxication with iron preparations

This impairs deposition of iron in the body

This causes malabsorption of iron

This causes increased binding to blood proteins

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Pharmaceutical analyst working at the laboratory of the State Inspectorate for Quality Control of Medicines identifies the drug substance 'Glucose anhydrous'with copper-tartrate solution ( Fehling’s reagent). What colour precipitate is produced?

Black

White

Purple

Red

Blue

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Senior nurse of the surgical department of the city hospital applied to the interhospital pharmacy. Specify the supporting document for the dispension of dressing material from this pharmacy:

Requisition

Invoice

Passport

Certificate

Tax invoice

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Under the SPh of Ukraine, one of the reactions for the detection of calcium cation presence in drugs is the reaction with:

Hydroxyquinoline

Sulfuric acid

Glyoxal-hydroxyanil

Alizarin

Hydroxylamine

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A pharmaceutical analyst working at the laboratory of the State Inspectorate for Quality Control of Medicines identifies 'Thiamine hydrobromide'with the solution of potassium ferricyanide in the alkaline medium. When doing this, he observes a light-blue fluorescence of the alcohol layer in UV light. What product is thus formed?

Quinoneimine

Ninhydrin

Thiochrome

Murexide

Thalleioquin

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Treatment of a patient who has developed an attack of bronchial asthma for the first time should be started with:

Inhalation of ^-agonists

Inhalation of glucocorticosteroid

Agonists parenterally

M-anticholinergic drugs

Яг-histamine blockers

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A patient with acute heart failure and cardiac glycoside intolerance was given an injection of dobutamine. What is the mechanism of its action?

Stimulation of M-cholinergic receptors

Inhibition of phosphodiesterase

Stimulation of ^-adrenoceptors

Stimulation of a 1 -adrenoceptors

Blockade of K+-, Na+-ATPase

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Specify the indicator which measures the total contribution of various solutes to the osmotic pressure of the solution:

Osmolality

Isohydricity

Apyrogenicity

Isoviscosity

Isotonicity

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When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the board members in a joint-stock company?

Unlimited and solidary

Limited to the amount of deposits

Limited to the contributions to the statutory fund and their property

Limited to the value of their shares

Limited to the double amount of deposits

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A pharmacy opens a bank account to store funds and conduct ongoing business transactions. What kind of account should be opened?

Deposit

Investment

Provisional

Letter of credit

Current

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A female patient has a sleep disorder after stress. Which of the following hypnotic drugs should be preferred for the treatment of insomnia?

Chloral hydrate

Aminazine

Barbital

Nitrozepam

Phenobarbital

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Precipitation reactions are used to establish the identity of drugs. Cation of sodium in sodium citrate can be identified by the formation of a white precipitate with:

Potassium permanganate

Iron (III) chloride

Potassium ferrocyanide

Barium chloride

Silver nitrate

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A pharmaceutical analyst analyzes xeroform. Which of the following reagents can he use to identify bismuth in xeroform?

Copper sulphate

Sodium sulfide

Potassium sodium tartrate

Ammonium hydroxide

Barium chloride

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It is required to perform the extraction of medical poisons isolated from the biological material by the method of VP Kramarenko. At the same time, what substance will be extracted from the acidic medium?

Codeine

Aminazine

Ephedrine

Papaverine

Benzonal

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A forensic medicine laboratory received some biological material. It should be tested for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:

Propanol acidified with oxalic acid

Chloroform

Water alkalized with ammonia solution

Ethanol acidified with oxalic acid

Water acidified with sulfuric acid

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Pharmacies prepare injectable solutions. Which solution is prepared without any stabilizer?

Novocaine solution

Solution of caffeine sodium benzoate

Sodium bicarbonate solution

Glucose solution

Sodium thiosulfate solution

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A pharmacy sells medicines. Which of the following medicines is on the list of the controlled substances?

Tramadol

Postinor

Gentamicin sulfate

Streptocid

Hydrocortisone acetate

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A pharmaceutist has to prepare an aqueous extract of medicinal plants. What can be used as a substitute of plant material in the drug preparation?

Aromatic water

Standardized extract concentrate

Liquid extract

Tincture

Thick extract

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A 65-year-old female patient with a fracture of mandible has been prescribed a drug from the group of narcotic analgesics. Specify this drug:

Promedol

Piracetam

Cinnarizine

Furosemide

Heparin

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A hypertensive patient has been prescribed a drug from the group of nonselective betablockers. Specify this drug:

Adrenaline hydrochloride

Anapriline

Neostigmine methylsulfate

Labetalol

Prazosin

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A patient has a history of cholelithiasis. What drug should be administered to prevent biliary colic?

Magnesium sulfate

Bisacodyl

Contrycal

Almagel

Pancreatin

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From the pharmaceutical stock select a reversible anticholinesterase drug to be administered to the patients with atony of the intestine and urinary bladder in the postoperative period:

Dithylinum

Proserin

Benzohexonium

Atropine sulfate

Phosphacolum

‹ Назад

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A patient after acute myocardial infarction has been recommended to take acetylsalicylic acid for 3-4 months. What effect of acetylsalicylic acid would be most relevant for this patient?

Antiinflammatory

Antiplatelet

Antipyretic

Spasmolytic

Analgesic

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Rose essential oil is used as an antiinflammatory and antispasmodic agent. It is localized in the following excretory structures:

Essential oil conceptacles

Secretory cells

Glandular spots

Glandular hairs

Essential oil glandules

‹ Назад

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Production, labour and socioeconomic relations between the head of a pharmaceutical company and the workforce are regulated by:

Statute

Collective agreement

Labour contract

Corporate code

Contract

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A pharmacy makes bulk purchases of health and hygiene products. The agent works under a contract with the manufacturer and operates on his account. The agent may be given the exclusive right to sell goods in certain regions. Specify this agent:

Wholesale agent

Commission agent

Consignee

Broker

Dealer

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A pharmaceutical company has made a decision to expand its activities. The process of the company’s activity expansion by penetration into new fields of the branch is called:

Centralization

Segmentation

Diversification

Integration

Conglomeration

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A pharmacy prepares ointments with extracts. What is the way to incorporate the dry and thick extracts into the ointments?

To disperse them with a liquid which is compatible with the base

To triturate them first with alcohol-water-glycerol [1:6:3] mixture

To dissolve them in water first

To incorporate them directly into the molten ointment base

To disperse them with ethanol

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A pharmacy received a prescription: Rp.: Dibazoli0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose :

0, 26

2, 7

0, 30

0, 25

0,27

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A pharmaceutist working at an analytical laboratory is engaged into sulfite-ion identification of a drug in compliance with the requirements of SPhU. What reagent becomes colourless in this study?

Ammonia solution

Potassium nitrate solution

Iron (III) chloride solution

Potassium iodide solution

Iodine solution

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Select a drug for the treatment of bronchial asthma from the group of fi2-agonists:

Aminophylline

Beclomethasone

Atrovent

Salbutamol

Ketotifen

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Ampules are produced of glass with appropriate heat resistance. An ampule would meet the requirements of technical standards if the ampule glass has the following characteristic:

Easy cutting of capillaries

Withstanding the stresses during production and transportation

Quality ampule sealing

Thermal shock resistance

Protection of light-sensitive materials

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Ampule quality control involves testing for chemical resistance. What methods are used to test this indicator?

Photoelastic method

Visual, gravimetric methods

Various acid-base indicators, pH meter, gravimetric methods

Autoclaving followed by titration with a solution of hydrochloric acid

Exposing the glass samples to the action of sodium carbonate and sodium hydrocarbonate solutions

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A pharmaceutist prepared the massage cream of the following composition: Beeswax 12,0 Almond oil 68,5 Spermaceti 12,0 Anhydrous lanolin 7,5 Essential oil of lavender 3 drops. Specify the cream type:

Emulsion

Oily

Combined

Suspension

Non-oily

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What is the function of anhydrous lanolin in the suppository mass used for suppositories prepared by hand rolling?

Solubilizer

Preservative

Solvent

Plasticizer

Emollient

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Plantain leaves are used for production of Plantaglucidum which has antiulcerogenic action. The plant material analysis involves quantitative determination of the following class of compounds:

Terpenes

Amarines

Polysaccharides

Carotenoids

Vitamins

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What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?

Vinblastine

Securinine nitrate

Glaucine hydrochloride

Ergotamine

Novopassit

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A pharmaceutist has prepared a suspension with a hydrophobic substance. What stabilizer is required for its preparation?

Glucose

5% solution of methyl cellulose

Sodium chloride

Sodium thiosulfate

Polyethylene oxide

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A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?

Dichlorvos

Hexachlorocyclohexane

Ethyl mercury chloride

DDT

Heptachlor

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Which of the following sublingual drugs quickly relieves an attack of stenocardia?

Amiodarone

Digoxin

Corglycon

Lisinopril

Nitroglycerine

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Diazepam is used for the treatment of neuroses due to the following pharmacological effect:

Antipyretic

Antidepressant

Analgesic

Diuretic

Anxiolytic

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A patient has been administered a spasmolytic from the group of muscarinic receptor antagonists as a part of the complex treatment for renal colic. Specify this drug:

Galantamine

Benzohexonium

Neostigmine

Atropine

Dithylinum

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One of the recent industrial medical forms that is used in pediatric practice and intended for young children unable of swallowing tablets is:

Gelatin microcapsules

Spansules

Tubatines

Granules

Dragee

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What final document is used for the preparation of the report on the discrepancies revealed in course of the inventory at the pharmacy?

Commercial report

Invoice

Checklist

Inventory item description

Act on the inventory results

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Pharmaceutical market of Ukraine comprises pharmacies of various forms of ownership. Specify the form of ownership for a community pharmacy:

Private person

Workforce of an enterprise

-

Group of shareholders

Territorial community

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A patient with a history of allergic rhinitis has been prescribed ephedrine in form of nasal drops. The patient has significantly benefited from nasal instillation, and this stimulated him to use the drug every two hours. But under these conditions the drug appeared to be ineffective. What is the most likely cause of this phenomenon?

Idiosyncrasy

Tachyphylaxis

Cumulation

Allergy

Drug dependence

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A pharmaceutic plant producing aerosol forms uses liquefied gases as propellents. Which of the following substances relates to the group of liquefied gases?

Nitrogen

Freons

Ethylene chloride

Nitrous oxide

Methylene chloride

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A pharmaceutist has to prepare a drug by the prescription: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place :

Sodium benzoate

Mint water

Sodium hydrogen carbonate

Sugar syrup

Liquoris Ammonii anisatis

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A person got poisoned with an unknown substance. Chemico-toxicological test for the isolated toxin with Dragendorff’s, Sonnenschein’s, Schei-bler’s reagents caused setting of sediments. The specific study should be focused on the following group of toxic substances:

Metal toxins

Hydrocyanic acid

Methyl alcohol

Alkaloids and nitrogen-containing compounds

Ammonia and its salts

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A laboratory for drug quality control checks the quality of the drug substance nitrofural ( furacilin). The chemical denomination of this drug is :

5-Nitro-2-furaldehyde semicarbazone

1,2-Diphenyl-4-butylpyrazolidine-dione-3, 5

1-(5- Nitrofurfurilidenamino)imidazolidine-2,4-dione

N(-(2-Furantdil)-5-fluorouracil

7- Nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

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A 25-year-old patient with frequent migraine attacks has been prescribed sumatriptan. Specify the mechanism of its action:

Selective agonist of 5 — HTi-serotonin receptors

Selective antagonist of 5 — HTX-serotonin receptors

Stimulator of в-adrenergic receptors

Nonselective «-blocker

Selective «-blocker

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A 43-year-old patient with a severe form of rheumatoid arthritis has been administered a certain drug for background therapy. Specify this drug:

Methotrexate

Prednisolone

Diclofenac sodium

Nimesulide

Methylprednisolone

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In order to analyze marketing opportunities and make a forecast of the market position a pharmaceutical company can use a matrix allowing the company to find new markets ( geographical) or identify new areas of using traditional medicines. What matrix is used by a pharmaceutical company to identify its market position?

Competitive force models

Boston Consulting Group matrix

Porter’s matrix

Matrix of competitive advantages

Ansoff matrix

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A female 49-year-old patient complains of compressing headache in the occipital region, dizziness, increased AP. The patient has a history of diabetes melli-tus type II. What diuretic DOES NOT affect the blood glucose level?

Urea

Hypothiazide

Indapamide

Furosemide

Ethacrynic acid

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A 65-year-old patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient daily takes 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?

Food poisoning

Withdrawal syndrome

Hypersensitivity reaction

Tachyphylaxis

Glycoside intoxication

‹ Назад

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Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:

Methyl cellulose

Silicon

Hydrogenated fat

Vaseline, lanolin

Polyethylene oxide

‹ Назад

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Ampule workshop of a pharmaceutical factory produces the procaine hydrochloride solution. This solution is stabilized by adding:

0,1 mol/l of sodium hydrogen carbonate solution

20,0 of sodium hydrogen carbonate

0,1 mol/l of sodium hydroxide solution

0,1 mol/l of hydrochloric acid solution

1,5 g of amino-propylene glycol

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Some alkaline solution was added to the alcohol solution of ftivazide, causing the solution to change colour from the light yellow to the orange-yellow. Subsequent addition of hydrochloric acid made the solution become again light yellow, and then orange-yellow. What properties of ftivazide are proved by this reaction?

Reducing

Acid

Base

Amphoteric

Oxidative

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When atropine sulfate is tested for purity, the alkaloids and degradation products are detected by TLC. For this purpose the chromatographic plate is sprayed with a solution of:

Ninhydrin

Ammonia

Tetrabutylammonium hydroxide

Potassium iodobismuthate

Acetic-hydrochloric dini- trophenylhydrazine

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Specific impurity of thiosulfates in Natrii iodidum and Kalii iodidum is identified by adding starch and iodine solutions. The absence of impurities is proved by:

Discolouration of the solution

White precipitate

Disappearance of the blue colour

Blue colour

Yellow colour

‹ Назад

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Bronchodilatory effect of shortacting ^2-adrenoceptor agonist salbutamol develops after:

4-6 hours

45-60 minutes

20-30 minutes

5-10 minutes

2-3 hours

‹ Назад

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A12 weeks pregnant patient has been hospitalized with symptoms of acute cystitis. What antibiotic can be recommend in this case?

Tetracycline

Metronidazole

Amoxicillin

Ciprofloxacin

Gentamicin

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Issuing prescriptions and orders for drugs and medical products is regulated by the Order № 360 dated 19.07.2005 (as amended). Specify the prescription form for phenobarbital as a part of a combined dosage form:

F-2

No prescription

F-1

F-3 in duplicate

Prescription forms F-1 and F-3 in duplicate

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Vacation leaves for employees of pharmacies include paid annual, additional, sabbatical, social leaves, as well as unpaid leaves. What is the total duration of the paid basic and additional vacation leave?

70 calendar days

90 calendar days

59 calendar days

65 calendar days

60 calendar days

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Representatives of the family Solanaceae are widely used in medical practice as alkaloidcontaining plants. Which representative is the source for production of semi-synthetic steroid hormones?

Solanum tuberosum

Atropa belladonna

Hyoscyamus niger

Datura Stramonium

Solanum laciniatum

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After harvesting the calamus rhizomes the received material should be dried. What temperature range is required for obtaining good-quality raw material?

40-60 °C

35-40°C

80-90 °C

70-80 °C

60-70 °C

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A pharmaceutist has to prepare 10% alcohol solution of iodine. What is the required concentration of ethanol for this purpose?

95%

96 %

40 %

70 %

60 %

‹ Назад

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Field horsetail grass is recommend as a diuretic. What herbal material can be used as a substitute?

Herba Leonuri

Herba Menthae piperitae

Herba Adonidis

Herba Convallariae

Herba Aervae lanatae

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A pharmaceutist prepares an infusion at a ratio of 1:30. What plant material would be used?

Sage leaves

Marshmallow root

Lily of the valley grass

Oak bark

Shoots of Marsh Labrador tea

‹ Назад

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Under the SPhU (appendix 2), leaves of ginkgo are standardized by the content of:

Coumarins

Chromones

Alkaloids

Flavonoids

Saponins

‹ Назад

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The pharmaceutical market is characterized by the seasonal fluctuations in demand for anticold medicines. What kind of marketing is used in case of such demand?

Remarketing

Synchromarketing

Developing marketing

Conversive

Counteractive

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Economic analysis of pharmacy activity involves a number of absolute indices. What index is determined by the formula: 'income from sales - prime cost of goods':

Amount of costs

Total balance

Level of costs

Gross profit

Net profit

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Salicylic acid and its derivatives may be the cause of acute intoxication. When salicylates are analyzed by TLC method, the chromatographic plate is sprayed with:

Solution of iron (III) chloride

Solution of mercury (II) sulfate and chloroform solution

Dragendorff’s reagent

Marquis reagent

Forrest reagent

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The simple sugar syrup consists of:

64 parts of sugar and 36 parts of water

50 parts of sugar and 50 parts of water

45 parts of sugar and 55 parts of water

73 parts of sugar, 22 parts of water, 5 parts of 90% alcohol

65 parts of sugar, 33 parts of water, 2 parts of 90% alcohol

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Prescriptions for the controlled drugs dispensed under the reimbursement program (except for the narcotic and psychotropic preparations in substance) are issued on the following prescription form:

№3, single copy

№3 in duplicate

№1 in duplicate

№1, single copy

№1 and № 3

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Quarterly evaluation of business and financial performance of a pharmacy involves calculating its profitability. For this purpose the following data is used: turnover - 100 thousands UAH, gross profit - 25 thousands UAH, expenditures -1 thousand UAH. Calculate the profitability of the pharmacy:

15%

22 %

20 %

25 %

10 %

‹ Назад

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A patient suffering from epilepsy has taken phenobarbital for a long time and developed drug tolerance. What is the mechanism of this phenomenon development?

Absorption process reduction

Acceleration of biotransformation

Accumulation of substances in the body

Inhibition of biotransformation

Receptor’s sensitivity enhancement

‹ Назад

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Who is responsible for the acceptance of goods and medical products with accompanying incoming quality control?

Head of pharmacy

Analyst

Authorized representative

Supplier pharmaceutist

Pharmaceutist

‹ Назад

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During steam distillation of voltile poisons the first portion of the distillate is collected in a receiver with 2% solution of sodium hydroxide. It is used to detect:

Acetates

Formaldehyde

Cyanides

Ethanol

Phenol

‹ Назад

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Alkaloid glaucine has an antitussive effect that is stronger and longer if compared to that of codeine, and exhibits no narcotic side effects. What drug plant contains glaucine?

Thermopsis lanceolata

Datura

Henbane bell (Scopolia carniolica)

Celandine

Yellow hornpoppy

‹ Назад

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A pharmacy has no quinquelobate motherwort in stock. It can be substituted by the following herbal material:

Raspberry fruits

Beggarticks grass

Rhizomes and roots of valerian

Hypericum grass

Linden flowers

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Drug plant Dioscorea nipponica is the source for production of Polysponi-num drug which is used in the complex treatment of atherosclerosis. Specify the active compounds of dioscorea material:

Cardiac glycosides

Triterpene saponins

Steroidal saponins

Essential oil

Alkaloids

‹ Назад

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A drug raw material from the family Polygonaceae had been sent to a laboratory for analysis. On macroscopic examination the material was identified as a herbaceous plant with lanceolate leaves with a red spot, and filmy ocreae covered with appressed hairs. The plant had the apical inflorescence in dense spicate panicles. What plant is it?

Common knotweed

Biting knotweed

Common buckwheat

Snakeweed

Redshank (persicaria)

‹ Назад

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A 35-year-old patient with tachycardia has been administered propranolol. Which of the following reactions may be caused by the use of beta-blockers?

Drug dependence

Bronchospasm

Constipations

Cumulation

Blood pressure rise

‹ Назад

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Under the SPhU requirements mercury salts are indentified by means of interaction with sodium hydroxide solution. Specify the colour of the precipitate that is produced as a resut of this reaction:

Red

Blue

Yellow

Yellow-green

White

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A 17-year-old patient complains of persistent thirst, dry mouth, frequent urination, increased appetite. Blood glucose is at the rate of 11 mmol/l. The patient has been diagnosed with diabetes melli-tus type I. What drug is indicated for treatment?

Asparcamum

Glibenclamide

Maninil

Acarbose

Insulin

‹ Назад

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A pharmacy serves the polyclinics of a city district. Specify the bill of materials that shows the number of drugs dispensed on prescriptions of the doctors who work in the polyclinics:

-

Medical

Inpatient

Outpatient

Polyclinic

‹ Назад

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At the end of the reporting period a pharmacy makes an analysis of its commercial and financial activities. What economic index describing the commercial and financial performance is defined as the ratio of the pharmacy profit to the turnover?

Profitability

Wholesale turnover

Distribution costs

Retail turnover

Bill of material

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Phytochemical workshop of a factory manufactures pancreatin. What is the source material for obtaining pancreatin?

Gastric mucosa of pigs

Pancreas of pigs or cattle

Heart of cattle

Lungs of cattle

Egg white

‹ Назад

Далі ›

Which of the following diuretics SHOULD NOT be administered to patients with impaired hearing?

Clopamide

Spironolactone

Chlorthalidone

Furosemide

Indapamide

‹ Назад

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A patient who has been taking acetylsalicylic acid developed hemorrhages of mucous membranes. This phenomenon is associated with:

Inhibition of the prothrombin synthesis

Increased absorption in the gastrointestinal tract

Decreased absorption in the gastrointestinal tract

Disorder of protein binding

Changed volume of distribution

‹ Назад

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Simultaneous use of paracetamol and acetylcysteine causes:

Increase of paracetamol nephrotoxicity

Reduction of paracetamol hepatotoxi-city

Inhibition of paracetamol absorption

Reduction of anti-inflammatory action of paracetamol

Increase of mucolytic action of acetylcysteine

‹ Назад

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Simultaneous use of gentamicin and acyclovir tablets increases the risk of:

Likelihood of allergic reactions

Neurotoxicity

Cardiotoxicity

Hepatotoxicity

Nephrotoxicity

‹ Назад

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Simultaneous use of doxycycline hydrochloride and oral contraceptive causes:

-

Increase of the antibacterial effect of doxycycline

Increase of oral contraceptives effectiveness

Reduction of oral contraceptives effectiveness

Reduction of the antibacterial effect of doxycycline

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In case of simultaneous use of metronidazole and oral anticoagulants derived from coumarin patients must be warned about:

Reduction of anticoagulants effect

Higher neurotoxicity

Reduction of metronidazole effect

Potentiation of metronidazole effect

Potentiation of anticoagulants effect and the risk of bleeding

‹ Назад

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Business transactions of pharmacies are reported in the accounts. Specify the account that reports the settlements with debtors and creditors:

Negative

Trial balance

Business

Nominal

Positive

‹ Назад

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Apart from goods sales, there are other business transactions that can be characterized as goods disposal. Which of the following business transactions reduces the stock at pharmacies?

Reclassifying other supplies as goods

Disposal of products for economic needs

Bringing the glassware on charge

Revaluation for the packing and laboratory work

Bringing the oversupply on charge

‹ Назад

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A pharmaceutical analyst analyzes the substance of ascorbic acid in compliance with the requirements of the State Pharmacopoeia of Ukraine. To identify the oxalic acid impurities he uses the solution of:

Sodium sulfate

Sodium hydrocarbonate

Sodium thiosulfate

Calcium chloride

Sodium chloride

‹ Назад

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Phenobarbital drug has a sedative, hypnotic and anti-epileptic effect. What is its international nonproprietary name?

Chloramphenicol

Diazepam

Salol

Nitrofurazone

Luminal

‹ Назад

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A 70-year-old patient with stenocardia claims that the pharmacy sold him a drug that relieved an attack of stenocardia but instead caused an acute bursting headache. What antihypertensive drug is this side effect typical for?

Trimetazidine

Nifedipine

Metoprolol

Amlodipine

Nitrosorbid

‹ Назад

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During the working day a pharmaceutist prepared five dosage forms. Which of them requires a complete chemical control?

Antipruritic ointment

5 % aethonium solution

Ear drops with levomycitin

Eye drops 10 ml of 2% ethylmorphine hydrochloride solution

Mixtura Pavlovi

‹ Назад

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Commercial and financial activity of a pharmacy involves using returnable tare. Which of the following containers are returned to the supplier?

Paper boxes

Glass-stoppered bottles

Glassware

Packaging materials

Metal cylinders

‹ Назад

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A pharmacy plans to expand the production of medicines. For this purpose it purchased the production equipment at a cost of 7000 uAh. The cost of the equipment will be recorded to the balance of the pharmacy as:

Initial cost

Fair value

Revalued amount

Residual

Amortization cost

‹ Назад

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An accountant of a pharmacy issued a cash receipt voucher for the sales proceeds. What document is used to register cash receipt and cash payment vouchers before the cash arrives to the cashiers?

Ledger of cash dispensed and received by the senior teller

Pay list

Cash report

Register of receipt and payment cash documents

Cash book

‹ Назад

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Biochemical blood test revealed low level of serum iron. What disease are these changes typical for?

Pneumonia

Acute bronchitis

Iron-deficiency anemia

Bronchiectasis

Bronchial asthma

‹ Назад

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A patient who has been treated for hypertension complains of cough. Objective examination reveals no changes in the lungs. Which of the following drugs might have caused cough?

Hypothiazide

Captopril

Clonidine

Amlodipine

Nebivolol

‹ Назад

Далі ›

What non-narcotic antitussive drug of central action can be used for dry cough?

Codeine

Glaucine

Ambroxol

Mucaltin

Acetylcysteine

‹ Назад

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Galenic preparations are produced by using various extractants. What extractants require pressure as a prior condition for the extraction process?

Ethanol

Dichloroethane, chloroform

Liquefied gases

Methyl alcohol, acetone

Vegetable oils

‹ Назад

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Menthol has anesthetic and antiseptic effect. What plant is the source of menthol?

Folia Menthae piperitae

Folia Eucalypti

Folia Absinthii

Folia Salviae

Folia Uvae ursi

‹ Назад

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Hydrocyanic acid and its salts are extremely toxic substances. In humans, they are partly neutralized by enzymatic conversion into:

Thiocyanate

Acetic acid

Carbon (IV) oxide

Ethanol

Nitrogen (II) oxide

‹ Назад

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Methyl alcohol which is widely used in industry causes severe health disorders when enters the human body even in small amounts. This effect is induced by the action of the following major metabolites of methanol:

Formaldehyde and formate acid

Acetic acid and acetaldehyde

Ethyl alcohol and ethyl acetate

Ethanol and acetaldehyde

Methyl acetate and ethyl acetate

‹ Назад

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Enrolled in private pharmacies to implement a drug whose active ingredient is the chemical name of 2-chloro-10-(3’-dimethylaminopropyl)-phenothiazine hydrochloride. Specify this drug:

Clonidine hydrochloride

Promethazine hydrochloride

Chlorpromazine hydrochloride

Trifluoperazine hydrochloride

Diphenhydramine hydrochloride

‹ Назад

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The thyme grass is used for the production of herbal medical products for the treatment of respiratory tract infections. Under the SPhU, the herbal raw material is subject to chromatographic identification by means of thin layer chromatography. What substances are detected on the chromatographic plate after its treatment with due reagent?

Quercetin and rutin

Arbutin and methyl arbutin

Apigenin and luteolin

Thymol and carvacrol

Atropine and hyoscyamine

‹ Назад

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Flower buds of clove contain the essential oil used for production of herbal antiseptics. Under the State Pharmacopoeia of Ukraine, the raw materials are identified by the method of thin layer chromatography. What zones can be identified on the chromatographic plate after their treatment with reagent?

Apigenin and luteolin

Eugenol and caryophyllene

Scopoletin and umbeliferon

Hyoscyamine and scopolamine

Quercetin and rutin

‹ Назад

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Specify the base for the preparation of antibiotic ointments:

5 parts of vaseline + 5 part of lanolin

6 parts of vaseline + 4 part of lanolin

5 parts of vaseline + 1 part of lanolin

7 parts of vaseline + 3 part of lanolin

8 parts of vaseline + 2 part of lanolin

‹ Назад

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Business transactions of a pharmacy are recorded in the control accounts as listed in the chart of accounts. The balance on the ledger and sub-ledger accounts is used to fill out the following document:

Fourth section of the liabilities side

Assets

Liabilities

Profit and loss account

First section of the liabilities side

‹ Назад

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A 40-year-old patient has a history of bronchial asthma and heart rhythm disorders in form of bradyarrhythmias. Bronchospasm can be eliminated by the drugs of the following pharmacological group:

Cholinesterase inhibitors

в-blockers

M-cholinomimetics

Muscle relaxants

M-cholinergic antagonists

‹ Назад

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