Step 2 - Pharmacy 2013

It is required to prove the presence of bismuth ions in the mineral residue. What preliminary reaction is used for this purpose?

With potassium chromate

With dithizone

With 8-hydroxyquinoline

With sodium rhodizonate

With copper acetate

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A pharmacy prepared a solution of macromolecular substance with limited swelling capacity. What solution was labelled 'warm up before use'?

Gelatin

Pepsin

Pancreatin

Methyl cellulose

Trypsin

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A pharmacy rceived a prescription for ethyl alcohol. What amount of alcohol can be dispensed to the patient with diabetes free of charge?

100 g per month

200 g per month

50 g per month

150 g per month

There is no standard

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Schedule of sanitation actions in pharmacies is regulated by the relevant regulatory acts. Cleaning day at a pharmacy must be scheduled for at least 1 time:

In 10 days

In 5 days

In a week

In a month

In 3 days

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6 months after treatment a patient with coronary heart disease developed tolerance to the prolonged-action nitrates. What drug with nitrate-similar effect should be recommended in this case?

Prazosin

Metoprolol

Molsidomine

Nifedipine

Verapamil

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Losartan for treatment of arterial hypertension is contraindicated in case of:

Hyperlipidemia

Hypokalemia

Urine acid diathesis

Hyperglycemia

Pregnancy

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A patient with hypertensive crisis has been given an intravenous injection of clonidine. What mechanism underlies the antihypertensive effect of clonidine?

Blockade of в-adrenergic receptors

Blockade of peripheral a-adrenergic receptors

Stimulation of the central presynaptic a2-adrenergic receptors

Direct myotropic effect on blood vessels

Blockade of N-cholinergic receptors

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A patient with the symptoms of cardiac glycoside intoxication has been administered unitiol. What is the mechanism of therapeutic action of this drug?

Binding of the ionized Ca2+

Increase in Na+ level in the myocardium

Increased penetration of K + into the cardiac myocytes

Reactivation of the membrane K +, Na+-ATPase

Induction of cardiac glycosides metabolism

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A 38-year-old male patient with mercuric chloride intoxication has been delivered to the admission ward in grave condition. What antidote must be immediately administered the patient?

Atropine

Nalorphine

Izonitrozinum

Unithiol

Dipyroxime

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Standard herbal material of lily-of-the-valley is obtained by drying it at a temperature of 50-60 oC in order to prevent the following possible biochemical process :

Oxidation of terpenoids

Oxidation of resins

Oxidation of phenolic compounds

Enzymatic hydrolysis of cardiac glycosides

Volatilization of essential oils

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Which drug including the beta-lactam cycle in its structure gives a positive reaction with a solution of hydroxylamine hydrochloride in the presence of sodium hydroxide followed by adding the solution of iron (III) chloride?

Antipyrine

Papaverine hydrochloride

Dibazolum

Phenoxymethylpenicillin

Streptocid

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A pharmaceutical plant produces spi-ssum extract with 0,25% ammonia solution used as an extractant. This is a spissum extract of:

Licorice

Sagebrush

Motherwort

Male fern

Valerian

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A person got poisoned with the lead compounds. What is the most sensitive method of the quantitative analysis of lead ions?

Chelatometry

Photometry

Gravimetry

Dichromate iodimetry

Atomic absorption spectrometry

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A marketing manager of a pharmaceutical company carries out market research on vitamin preparation market. He takes into account various parameters including the therapeutical effectiveness, supply and demand. What method should be applied?

Method of extraction from the original medical records

Mathematical statistics method

Graph method

-

Delphi method

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A factrory workshop producing suspensions and emulsions is going to develop the manufacture of new drugs. What mechanisms can be used for the ultrasound processing of drugs?

Dismembrator, electrical impulse plasmolyzer

Liquid whistle, magnetostrictive source

Centrifugal mixer with rotating housing

Rotor-pulsation apparatus, di-smembrator

Disintegrator, liquid whistle

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A pharmaceutist prepared a lipophilic ointment of suspension type. What substance is used for preparing this kind of ointments?

Tannin

Menthol

Herbal extracts

Protargolum

Xeroform

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A pharmaceutist has a labour dispute with the pharmacy administration about rescheduling his annual vacation leave. The employee can appeal against the decision of the pharmacy administration to the following body:

Trade union committee

MoH of Ukraine

Commercial court

Labour disputes commission (LDC)

Highest management bodies of pharmaceutical service at the regional level

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Medications Passit and Novopassit are used as tranquilizing, sedative and mild hypnotic agents. These medications are produced from the following grass:

Lesser periwinkle

Garden sage

Purple passionflower

Elecampane

Three-lobe beggarticks

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During transportation, the markings on the packages of theobromine and theophylline were damaged. What solution allows to identify theobromine and theophylline?

Potassium dichromate

Copper nitrate

Cobalt chloride

Potassium permanganate

Sodium chloride

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Which of the following antihypertensive drugs has potassium-sparing action?

Diltiazem

Prazosin

Metoprolol

Triamterene

Furosemide

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What drug acts as a specific antidote in case of iron drug intoxication?

Bemegride

Atropine

Deferoxamine

Protamine sulfate

Penicillamine

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A regional medical representative of a foreign company uses the data derived from periodicals and reference and statistical materials in order to characterize the territorial pharmaceutical market. What kind of market research is based upon these sources?

This method does not apply to research

Desk studies

All answers are correct

Field studies

-

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A pharmaceutist was on a business trip. What is the deadline for submitting a travel expense report?

Four working days after returning from a trip

Three working days after returning from a trip

A week after returning from a trip

There is no deadline

Ten working days after returning from a trip

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An accountable person (accountant) has been given some cash from the cash account of the company for the purchase of stationery goods . What is the deadline for submitting a full statement of the accountable person on the cash use after receiving the cash?

There is no fixed term

Five working days

Third banking day

One week

Ten working days

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A pharmaceutist prepares trituration of atropine sulfate. What adjuvant should be used for this purpose?

Talc

Starch

Saccharose

Lactose

Glucose

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A pharmaceutical factory produces tablets of sodium chloride. What is the method of their poduction?

Direct compression with the addition of excipients

Wet granulation prior to compression

Direct compression without additional substances

Dry granulation prior to compression

Moulding

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A pharmaceutical factory produces suspensions and emulsions. Specify the equipment which is used for dispersion and mixing in the liquid medium:

Oscillating mixers

Anchor mixers

Drum mixers

Gate mixers

Rotor-pulsation apparatus, colloid mixers

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A pharmaceutist prepared eye drops containing silver nitrate. What substance must be taken to ensure isotonicity?

Sodium chloride

Boric acid

Sodium sulfate

Glucose

Sodium nitrate

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In order to detect the presence of thiosulfate ions a pharmaceutical analyst added the excess reagent. The resulting reaction produced a white precipitate, which slowly turned yellow, then brown, and black. What solution was added?

Lead (II) acetate

Silver nitrate

Ammonium oxalate

Diphenylamine

Barium chloride

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Collective labour agreement is concluded by a trade union committee with the enterprise owner on behalf of the workforce. Any collective agreement is worked out in written form. Which article of the Labor Code regulates the duration of the collective agreement?

41

36

40

38

17

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A person got poisoned with salts of manganese. Analysis of the mineral residue revealed manganese ions. What reactions underlie the chemical processes of manganese detection?

Neutralization

Oxidation-reduction

Hydrolysis

Dissociation

Metathesis

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A pharmaceutist prepares a solution for injections that must be stabilized with 0,1M of hydrochloric acid solution. What solution is to be prepared?

Sodium benzoate

Novocaine

Hexamethylenetetramine

Potassium chloride

Calcium chloride

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Paracetamol substance has been sent for analysis. Reaction with the solution of iron (III) chloride gave the blue-purple colour. This indicates the presence of:

Keto group

Phenolic hydroxyl

Aldehyde group

Ester group

Alcoholic hydroxyl

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Production of tablets requires stage-to-stage quality control. What devices are used to determine the particle size distribution (fraction) of granules?

Laboratory IDs

Various vibrosieves

Microscope

Friabilators

Standard set of sieves

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Analysis of the drug sales performance revealed market expansion, the absolute increase of the drug in manufacturer’s stocks, slowdown in the growth rate of sales, intense competition. What stage of the product life cycle is the drug in?

Development

Introduction

Growth

Maturity

Saturation and decline

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Anthracene derivatives of emodin have purgative effect. Large quantities of anthracenederived groups of emodin are contained in the fruits of the following plant:

Blueberry (Vaccinium myrtillus)

Buckthorn

Elder (Sambucus)

Alder buckthorn (Frangula alnus)

Blackcurrant

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Theory of management currently points out four the most important approaches to the management. Select the approach that is NOT applied in the theory of management:

Systemic

Process approach

Different schools dedication approach

Situational

Structured

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A pharmaceutist worked on a holiday, and the time worked was within the normal working hours of the current month. The employee would be entitled to be paid:

According to the standard procedure as for a normal working day

There would be no penalty rates

Fixed salary + one daily rate

Single piecework rate

Fixed salary + double daily rate

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A pharmacy has a license for selling narcotic drugs. The warrant for the receipt of these drugs from the pharmacy warehouse is valid for:

No longer than one calendar days from the date of issue

No longer than three months from the date of issue

No longer than one year from the date of issue

No longer than five calendar days from the date of issue

No longer than 10 calendar days from the date of issue

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Help the doctor to select a drug for the replacement therapy after the thyroid gland removal:

Prednisolone

Parathyroidin

L-thyroxine

Insulin

Mercazolilum

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Chloride of lime is identified by calcium cations after boiling with acetic acid in order to eliminate active chlorine. What reagent is used?

Potassium chloride

Magnesium sulfate

Ammonium oxalate

Sodium nitrite

Ammonium molybdate

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The medicine 'Bismuthi subnitras'can be identified after dissolving it in the acid with the following reagent:

Potassium nitrate

Sodium chloride

Potassium iodide

Sodium sulfate

Potassium chlorate

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Sterilization methods used for the preparation of drugs under aseptic conditions can be differentiated into physical, mechanical, and chemical ones. Specify the chemical method of sterilization:

Pressure steam sterilization

Radiation sterilization

Dry heat sterilization

Addition of preservatives

UV light sterilization

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Activity of a company leader involves managerial decision-making aimed at the achievement of corporate goals. Which of the following decisions are NOT classified by the method of justification?

Rational

Intuitive

Standard

-

Decisions based upon judgements

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Pharmacies prepare triturations of toxic and superpotent substances. They can be prepared in a following ratio:

1:1000

1:10 and 1:100

1:10 only

1:100 only

1:500

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It is required to prepare furacilin solution (1:5000). What is the dissolution peculiarity of furacilin?

It dissolves in the filtered purified water

It dissolves in the boiling water purified in the presence of sodium chloride

It dissolves in the purified water after the trituration

It dissolves in the cold purified water

It dissolves in a minimal amount of ethyl alcohol

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The method of suspension preparation depends on the properties of its components. Specify the substances having hydrophobic properties:

Camphor, menthol

Sodium bicarbonate, sodium sulfate

Boric acid, calcium carbonate

Zinc oxide, talc

White clay, bentonite

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A patient has been prescribed hand-rolled rectal suppositories with 0,1 g of aminophylline. What is the amount of base required for each suppository, provided that the suppository weight is not specified in the formulation?

2,4 g

1,9 g

1,4 g

3,9 g

2,9 g

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Pharmaceutical depot received a batch of herbal material of cinnamon rose. What substance determines the quality of the raw material?

Ascorbic acid

Coumarins

Essential oil

Anthracene derivatives

Tannins

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A pharmaceutist prepares an ointment on a hydrophobic base. What substance does he use in order to reduce the melting point of the base?

Dimexide

Glycerol

Ethanol

Vaseline oil

PEG-40

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In order to identify deoxycorticosterone acetate a pharmaceutical analyst performed a steroid cycle reaction, which resulted in formation of cherry-red colour and a green fluorescence. What reagent was added?

Iron (III) chloride solution

Potassium hydroxide solution

Concentrated sulfuric acid

Iodine solution

Chloroform

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An analytical laboratory received a sample of alpha-aminobutyric acid for analysis. What reagent should be used by the analyst in order to identify this substance?

Benzene

Calcium bromide

Aniline

Ninhydrin

Sodium nitrate

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A retail pharmacy has been purchasing goods within an accounting period. What changes to the balance will result from this business transaction?

Increase in assets and liabilities

Changes will be caused to the assets only

Decrease in assets and liabilities

Changes will be caused to the liabilities only

-

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Leaves of greater plantain are harvested in summer by mowing or cutting them with a knife or a sickle. There is always one developed plant left per 1 m2. The plant is harvested in the following vegetation period:

Beginning of fruiting

Blooming

Ripeness

Rosetting

Budding

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A manufacturing enterprise plans to sell a new drug through the corporate chain of pharmacies. What strategy of drug distribution would be used?

Direct

Flexible

Multi-echelon

Horizontal integration

Vertical integration

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The quality of tablets is assessed by various factors. What instrument is used for the tablet disintegration test?

Paddle

-

Friabilator

Basket apparatus

Flow-through device

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A pharmaceutical manufacturer develops a system of product. The focus is laid on the maximum involvement of agent network. What type of marketing is applied?

Intense

Selective

Exclusive

Combined

-

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While preparing marshmallow root extract, a pharmaceutist mistakenly used the water of improper temperature for this extract, and the end product came up turbid. What is the required water temperature for the extraction of this herbal material?

60 oC

100 oC

40 oC

Room temperature

80 oC

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A 67-year-old patient with chronic heart failure takes digoxin. In order to reduce its side effects the patient’s doctor recommended to combine it with the followig drug:

Panangin

Euphyllinum

Calcium gluconate

Hydrochlorthiazide

Calcium chloride

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A certain plant is used for production of tinctures and extracts which are the part of complex drugs Bellataminal, Becarbon, Besalol, etc. Specify the grass that is used for this purpose:

Astragalus

Celandine

Lily of the valley

Belladonna

Beggarticks

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A woman who has been treated for infiltrative focal tuberculosis for a long time complains of acute hearing impairment. Which of the following preparations might be the cause of this side effect?

Rifampicin

Streptomycin

Ethambutol

Isoniazid

Ethionamidum

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A pharmaceutist prepared a drug by the prescription: Rp.: Streptocidi Dermatoli ana 1,0 Lanolini Vaselini ana 5,0 M.D.S.: Apply to the affected skin. Specify the type of the disperse system:

Suspension ointment

Hydrophilic ointment

Combined ointment

Solution ointment

Extraction ointment

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Which of the following antibiotics can be identified by means of the maltol test?

Streptomycin sulfate

Lincomycin hydrochloride

Kanamycin monosulfate

Amoxicillin

Doxycycline hydrochloride

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Pharmacies as legal entities must have statutory capital in order to get registered with state authorities. Specify the amount which is identified as the statutory capital:

Total assets

Total sources of funds

Outstanding amount

Amount recorded in the constituent documents

Amount of noncurrent assets

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A pharmaceutist prepared 100,0 g of oil emulsion using 5% solution of methyl cellulose as an emulsifier. Specify the required amount of oil and emulsifier for the drug preparation:

20,0 g,10,0g

10,0 g, 20,0 g

10,0 g, 30,0 g

10,0 g, 10,0 g

20,0 g, 30,0 g

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A pharmaceutist prepared the 2% aqueous solution by dissolving the drug substance triturated in a mortar. What substance is this technology typical for?

Potassium permanganate

Potassium bromide

Boric acid

Calcium gluconate

Osarsolum

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A pharmaceutist prepares powders with papaverine hydrochloride. What hand scales should be used for weighing out 0,05 g of substance?

BP 10,0

BP 2,0

BP 1,0

BP 20,0

BP 5,0

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What drug can be recommended for symptomatic treatment of muscle pain in a 5-year-old child?

Diclofenac sodium

Celecoxib

Acetylsalicylic acid

Indomethacin

Paracetamol

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A pharmacy received a prescription for an oil liniment including streptocidum. What is the type of disperse system of this preparation?

Alloy

Combined

Emulsion

Suspension

Solution

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White precipitate produced by the reaction of morphine hydrochloride with ammonia solution dissolves in sodium hydroxide solution due to the presence of the following group in the structure of morphine hydrochloride:

Carboxyl group

Alcoholic hydroxyl

Keto group

Aldehyde group

Phenolic hydroxyl

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A person got poisoned with alcohols. What alcohol derivatives are used for the analysis by gasliquid chromatography?

Alkyl sulfates

Alkyl acetates

Alkyl nitrates

Alkyl sulfites

Alkyl nitrites

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A pharmaceutical analyst identifies the substance of potassium acetate. What reagent confirms the presence of potassium cation in the substance?

Zinc oxide

Sodium hydroxide

Iron (III) chloride

Potassium permanganate

Tartaric acid

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According to SPhU, formaldehyde can be identified when a sample is reacted with chromotropic acid solution in the presence of concentrated sulfuric acid. What colour is formed by this reaction?

Yellow

Green

Blue

Brown

Violet

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Stimulation of beta-cells of the pancreas causes the hypoglycemic effect of the following drug:

Glibenclamide

Retabolilum

Prednisolone

Adrenaline hydrochloride

Heparin

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A patient with Parkinson’s disease has been prescribed a drug with a predominant effect on the dopaminergic system. What drug is it?

Levodopa

Zopiclone

Droperidol

Aminazine

Lorazepam

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Exacerbation of urolithiasis has caused a renal colic in the patient. What drug must be administered to arrest the colic?

Drotaverine hydrochloride

Neostigmine methylsulfate

Siliborum

Aethimizolum

Almagel

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A patient with atopic dermatitis presented to the hospital. Which drug with anti-inflammatory and antiallergic effect should be administered to this patient?

Oxytocin

Retabolilum

Aethamidum

Insulin

Prednisolone

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What solution is used for the detection of iron (II) ions under the SPhU requirements?

Lanthanum nitrate

Ammonia

Silver nitrate

Potassium ferricyanide

Sodium hydroxide

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The manufacturing pharmaceutical company Elema set up its own corporate pharmacy. In this case, it uses the following distribution channel:

Second level

Zero level

Fourth level

First level

Third level

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An analytical laboratory has the task to confirm the presence of ethylenedi-amine in the aminophylline. Which of the following reagents alows to detect ethylenediamine?

Copper (II) sulfate

Concentrated sulfuric acid

Silver nitrate

Sodium hydroxide

Barium chloride

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Help the doctor to select a drug from the group of non-steroidal antiinflammatory drugs, which is an inhibitor of COX-2 and does not damage the stomach:

Acetylsalicylic acid

Paracetamol

Diclofenac sodium

Indomethacin

Celecoxib

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A patient with acute intoxication has been administered a loop diuretic in order to cause the forced diuresis. What drug is it?

Mannitol

Triamterene

Hydrochlorothiazide

Spironolactone

Furosemide

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A hypertensive patient has been administered lisinopril. What side effect is typical for this drug?

Insomnia

Dry cough

Increased appetite

Vomiting

Constipation

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Advise an internship doctor on why iron preparations should not be administered along with antacids:

This causes malabsorption of iron

This accelerates elimination of iron preparations

This increases intoxication with iron preparations

This causes increased binding to blood proteins

This impairs deposition of iron in the body

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Pharmaceutical analyst working at the laboratory of the State Inspectorate for Quality Control of Medicines identifies the drug substance 'Glucose anhydrous'with copper-tartrate solution ( Fehling’s reagent). What colour precipitate is produced?

Purple

Black

Red

Blue

White

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Senior nurse of the surgical department of the city hospital applied to the interhospital pharmacy. Specify the supporting document for the dispension of dressing material from this pharmacy:

Passport

Certificate

Requisition

Invoice

Tax invoice

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Under the SPh of Ukraine, one of the reactions for the detection of calcium cation presence in drugs is the reaction with:

Alizarin

Sulfuric acid

Hydroxyquinoline

Hydroxylamine

Glyoxal-hydroxyanil

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A pharmaceutical analyst working at the laboratory of the State Inspectorate for Quality Control of Medicines identifies 'Thiamine hydrobromide'with the solution of potassium ferricyanide in the alkaline medium. When doing this, he observes a light-blue fluorescence of the alcohol layer in UV light. What product is thus formed?

Thiochrome

Quinoneimine

Murexide

Ninhydrin

Thalleioquin

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Treatment of a patient who has developed an attack of bronchial asthma for the first time should be started with:

Inhalation of glucocorticosteroid

Яг-histamine blockers

Inhalation of ^-agonists

M-anticholinergic drugs

Agonists parenterally

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A patient with acute heart failure and cardiac glycoside intolerance was given an injection of dobutamine. What is the mechanism of its action?

Stimulation of a 1 -adrenoceptors

Inhibition of phosphodiesterase

Stimulation of ^-adrenoceptors

Stimulation of M-cholinergic receptors

Blockade of K+-, Na+-ATPase

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Specify the indicator which measures the total contribution of various solutes to the osmotic pressure of the solution:

Isohydricity

Isotonicity

Isoviscosity

Osmolality

Apyrogenicity

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When setting up a joint-stock company the founders discussed the issues of financial liability. What is the liability of the board members in a joint-stock company?

Limited to the contributions to the statutory fund and their property

Limited to the value of their shares

Unlimited and solidary

Limited to the double amount of deposits

Limited to the amount of deposits

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A pharmacy opens a bank account to store funds and conduct ongoing business transactions. What kind of account should be opened?

Provisional

Letter of credit

Current

Investment

Deposit

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A female patient has a sleep disorder after stress. Which of the following hypnotic drugs should be preferred for the treatment of insomnia?

Aminazine

Nitrozepam

Barbital

Chloral hydrate

Phenobarbital

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Precipitation reactions are used to establish the identity of drugs. Cation of sodium in sodium citrate can be identified by the formation of a white precipitate with:

Silver nitrate

Barium chloride

Potassium permanganate

Potassium ferrocyanide

Iron (III) chloride

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A pharmaceutical analyst analyzes xeroform. Which of the following reagents can he use to identify bismuth in xeroform?

Ammonium hydroxide

Potassium sodium tartrate

Barium chloride

Copper sulphate

Sodium sulfide

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It is required to perform the extraction of medical poisons isolated from the biological material by the method of VP Kramarenko. At the same time, what substance will be extracted from the acidic medium?

Aminazine

Benzonal

Ephedrine

Codeine

Papaverine

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A forensic medicine laboratory received some biological material. It should be tested for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:

Propanol acidified with oxalic acid

Water alkalized with ammonia solution

Ethanol acidified with oxalic acid

Water acidified with sulfuric acid

Chloroform

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Pharmacies prepare injectable solutions. Which solution is prepared without any stabilizer?

Solution of caffeine sodium benzoate

Novocaine solution

Sodium bicarbonate solution

Sodium thiosulfate solution

Glucose solution

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A pharmacy sells medicines. Which of the following medicines is on the list of the controlled substances?

Gentamicin sulfate

Streptocid

Hydrocortisone acetate

Tramadol

Postinor

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A pharmaceutist has to prepare an aqueous extract of medicinal plants. What can be used as a substitute of plant material in the drug preparation?

Liquid extract

Thick extract

Standardized extract concentrate

Aromatic water

Tincture

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A 65-year-old female patient with a fracture of mandible has been prescribed a drug from the group of narcotic analgesics. Specify this drug:

Furosemide

Promedol

Heparin

Piracetam

Cinnarizine

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A hypertensive patient has been prescribed a drug from the group of nonselective betablockers. Specify this drug:

Adrenaline hydrochloride

Neostigmine methylsulfate

Anapriline

Prazosin

Labetalol

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A patient has a history of cholelithiasis. What drug should be administered to prevent biliary colic?

Contrycal

Bisacodyl

Magnesium sulfate

Pancreatin

Almagel

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From the pharmaceutical stock select a reversible anticholinesterase drug to be administered to the patients with atony of the intestine and urinary bladder in the postoperative period:

Proserin

Benzohexonium

Atropine sulfate

Dithylinum

Phosphacolum

‹ Назад

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A patient after acute myocardial infarction has been recommended to take acetylsalicylic acid for 3-4 months. What effect of acetylsalicylic acid would be most relevant for this patient?

Antiplatelet

Antiinflammatory

Spasmolytic

Antipyretic

Analgesic

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Rose essential oil is used as an antiinflammatory and antispasmodic agent. It is localized in the following excretory structures:

Glandular hairs

Essential oil conceptacles

Glandular spots

Essential oil glandules

Secretory cells

‹ Назад

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Production, labour and socioeconomic relations between the head of a pharmaceutical company and the workforce are regulated by:

Contract

Statute

Labour contract

Corporate code

Collective agreement

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A pharmacy makes bulk purchases of health and hygiene products. The agent works under a contract with the manufacturer and operates on his account. The agent may be given the exclusive right to sell goods in certain regions. Specify this agent:

Commission agent

Dealer

Consignee

Broker

Wholesale agent

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A pharmaceutical company has made a decision to expand its activities. The process of the company’s activity expansion by penetration into new fields of the branch is called:

Integration

Conglomeration

Diversification

Centralization

Segmentation

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A pharmacy prepares ointments with extracts. What is the way to incorporate the dry and thick extracts into the ointments?

To disperse them with a liquid which is compatible with the base

To dissolve them in water first

To incorporate them directly into the molten ointment base

To triturate them first with alcohol-water-glycerol [1:6:3] mixture

To disperse them with ethanol

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A pharmacy received a prescription: Rp.: Dibazoli0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose :

2, 7

0, 26

0, 30

0,27

0, 25

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A pharmaceutist working at an analytical laboratory is engaged into sulfite-ion identification of a drug in compliance with the requirements of SPhU. What reagent becomes colourless in this study?

Iron (III) chloride solution

Potassium nitrate solution

Potassium iodide solution

Iodine solution

Ammonia solution

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Select a drug for the treatment of bronchial asthma from the group of fi2-agonists:

Beclomethasone

Aminophylline

Salbutamol

Atrovent

Ketotifen

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Ampules are produced of glass with appropriate heat resistance. An ampule would meet the requirements of technical standards if the ampule glass has the following characteristic:

Easy cutting of capillaries

Protection of light-sensitive materials

Thermal shock resistance

Withstanding the stresses during production and transportation

Quality ampule sealing

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Ampule quality control involves testing for chemical resistance. What methods are used to test this indicator?

Photoelastic method

Exposing the glass samples to the action of sodium carbonate and sodium hydrocarbonate solutions

Various acid-base indicators, pH meter, gravimetric methods

Visual, gravimetric methods

Autoclaving followed by titration with a solution of hydrochloric acid

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A pharmaceutist prepared the massage cream of the following composition: Beeswax 12,0 Almond oil 68,5 Spermaceti 12,0 Anhydrous lanolin 7,5 Essential oil of lavender 3 drops. Specify the cream type:

Oily

Suspension

Non-oily

Combined

Emulsion

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What is the function of anhydrous lanolin in the suppository mass used for suppositories prepared by hand rolling?

Solubilizer

Preservative

Solvent

Emollient

Plasticizer

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Plantain leaves are used for production of Plantaglucidum which has antiulcerogenic action. The plant material analysis involves quantitative determination of the following class of compounds:

Carotenoids

Polysaccharides

Terpenes

Vitamins

Amarines

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What herbal drug produced form alkaloid-containing raw materials can be recommended for neurasthenia, insomnia, menopausal disorders?

Securinine nitrate

Glaucine hydrochloride

Ergotamine

Vinblastine

Novopassit

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A pharmaceutist has prepared a suspension with a hydrophobic substance. What stabilizer is required for its preparation?

Sodium thiosulfate

5% solution of methyl cellulose

Polyethylene oxide

Glucose

Sodium chloride

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A patient has been found to have pesticide intoxication. Biochemical (cholinesterase) test was positive. What pesticide is likely to have caused the intoxication?

DDT

Dichlorvos

Hexachlorocyclohexane

Heptachlor

Ethyl mercury chloride

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Which of the following sublingual drugs quickly relieves an attack of stenocardia?

Digoxin

Corglycon

Amiodarone

Lisinopril

Nitroglycerine

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Diazepam is used for the treatment of neuroses due to the following pharmacological effect:

Analgesic

Diuretic

Antidepressant

Anxiolytic

Antipyretic

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A patient has been administered a spasmolytic from the group of muscarinic receptor antagonists as a part of the complex treatment for renal colic. Specify this drug:

Neostigmine

Dithylinum

Atropine

Benzohexonium

Galantamine

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One of the recent industrial medical forms that is used in pediatric practice and intended for young children unable of swallowing tablets is:

Spansules

Tubatines

Gelatin microcapsules

Dragee

Granules

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What final document is used for the preparation of the report on the discrepancies revealed in course of the inventory at the pharmacy?

Invoice

Inventory item description

Checklist

Act on the inventory results

Commercial report

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Pharmaceutical market of Ukraine comprises pharmacies of various forms of ownership. Specify the form of ownership for a community pharmacy:

Private person

Workforce of an enterprise

Territorial community

-

Group of shareholders

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A patient with a history of allergic rhinitis has been prescribed ephedrine in form of nasal drops. The patient has significantly benefited from nasal instillation, and this stimulated him to use the drug every two hours. But under these conditions the drug appeared to be ineffective. What is the most likely cause of this phenomenon?

Allergy

Cumulation

Drug dependence

Idiosyncrasy

Tachyphylaxis

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A pharmaceutic plant producing aerosol forms uses liquefied gases as propellents. Which of the following substances relates to the group of liquefied gases?

Nitrogen

Ethylene chloride

Methylene chloride

Freons

Nitrous oxide

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A pharmaceutist has to prepare a drug by the prescription: Rp.: Natrii hydrocarbonatis 2,0 Natrii benzoatis 1,5 Liquoris Ammonii anisatis 4 ml Aquae Mentae 100 ml M.D.S. 1 tablespoon 3 times a day. Specify the component that is added in the first place :

Liquoris Ammonii anisatis

Sodium hydrogen carbonate

Sodium benzoate

Mint water

Sugar syrup

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A person got poisoned with an unknown substance. Chemico-toxicological test for the isolated toxin with Dragendorff’s, Sonnenschein’s, Schei-bler’s reagents caused setting of sediments. The specific study should be focused on the following group of toxic substances:

Ammonia and its salts

Alkaloids and nitrogen-containing compounds

Hydrocyanic acid

Metal toxins

Methyl alcohol

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A laboratory for drug quality control checks the quality of the drug substance nitrofural ( furacilin). The chemical denomination of this drug is :

7- Nitro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

1,2-Diphenyl-4-butylpyrazolidine-dione-3, 5

N(-(2-Furantdil)-5-fluorouracil

5-Nitro-2-furaldehyde semicarbazone

1-(5- Nitrofurfurilidenamino)imidazolidine-2,4-dione

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A 25-year-old patient with frequent migraine attacks has been prescribed sumatriptan. Specify the mechanism of its action:

Stimulator of в-adrenergic receptors

Selective agonist of 5 — HTi-serotonin receptors

Selective antagonist of 5 — HTX-serotonin receptors

Selective «-blocker

Nonselective «-blocker

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A 43-year-old patient with a severe form of rheumatoid arthritis has been administered a certain drug for background therapy. Specify this drug:

Prednisolone

Diclofenac sodium

Methylprednisolone

Nimesulide

Methotrexate

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In order to analyze marketing opportunities and make a forecast of the market position a pharmaceutical company can use a matrix allowing the company to find new markets ( geographical) or identify new areas of using traditional medicines. What matrix is used by a pharmaceutical company to identify its market position?

Ansoff matrix

Boston Consulting Group matrix

Matrix of competitive advantages

Competitive force models

Porter’s matrix

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A female 49-year-old patient complains of compressing headache in the occipital region, dizziness, increased AP. The patient has a history of diabetes melli-tus type II. What diuretic DOES NOT affect the blood glucose level?

Furosemide

Hypothiazide

Ethacrynic acid

Indapamide

Urea

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A 65-year-old patient complains of nausea, vomiting, lethargy, seeing yellow spots in front of his eyes. The patient daily takes 0,25 mg of digoxin, 100 mg of aspecardum, 50 mg of metoprolol. What pathological condition is this syndrome typical for?

Withdrawal syndrome

Tachyphylaxis

Glycoside intoxication

Food poisoning

Hypersensitivity reaction

‹ Назад

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Pharmaceutical plants produce ointments on various bases. Specify the ointment base having the most pronounced osmotic properties:

Vaseline, lanolin

Silicon

Methyl cellulose

Hydrogenated fat

Polyethylene oxide

‹ Назад

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Ampule workshop of a pharmaceutical factory produces the procaine hydrochloride solution. This solution is stabilized by adding:

20,0 of sodium hydrogen carbonate

1,5 g of amino-propylene glycol

0,1 mol/l of sodium hydroxide solution

0,1 mol/l of sodium hydrogen carbonate solution

0,1 mol/l of hydrochloric acid solution

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Some alkaline solution was added to the alcohol solution of ftivazide, causing the solution to change colour from the light yellow to the orange-yellow. Subsequent addition of hydrochloric acid made the solution become again light yellow, and then orange-yellow. What properties of ftivazide are proved by this reaction?

Oxidative

Acid

Base

Reducing

Amphoteric

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When atropine sulfate is tested for purity, the alkaloids and degradation products are detected by TLC. For this purpose the chromatographic plate is sprayed with a solution of:

Ninhydrin

Acetic-hydrochloric dini- trophenylhydrazine

Ammonia

Tetrabutylammonium hydroxide

Potassium iodobismuthate

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Specific impurity of thiosulfates in Natrii iodidum and Kalii iodidum is identified by adding starch and iodine solutions. The absence of impurities is proved by:

White precipitate

Discolouration of the solution

Disappearance of the blue colour

Blue colour

Yellow colour

‹ Назад

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Bronchodilatory effect of shortacting ^2-adrenoceptor agonist salbutamol develops after:

45-60 minutes

20-30 minutes

2-3 hours

4-6 hours

5-10 minutes

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A12 weeks pregnant patient has been hospitalized with symptoms of acute cystitis. What antibiotic can be recommend in this case?

Ciprofloxacin

Amoxicillin

Tetracycline

Gentamicin

Metronidazole

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Issuing prescriptions and orders for drugs and medical products is regulated by the Order № 360 dated 19.07.2005 (as amended). Specify the prescription form for phenobarbital as a part of a combined dosage form:

F-3 in duplicate

F-1

F-2

No prescription

Prescription forms F-1 and F-3 in duplicate

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Vacation leaves for employees of pharmacies include paid annual, additional, sabbatical, social leaves, as well as unpaid leaves. What is the total duration of the paid basic and additional vacation leave?

70 calendar days

59 calendar days

65 calendar days

90 calendar days

60 calendar days

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Representatives of the family Solanaceae are widely used in medical practice as alkaloidcontaining plants. Which representative is the source for production of semi-synthetic steroid hormones?

Solanum laciniatum

Atropa belladonna

Hyoscyamus niger

Solanum tuberosum

Datura Stramonium

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After harvesting the calamus rhizomes the received material should be dried. What temperature range is required for obtaining good-quality raw material?

80-90 °C

70-80 °C

60-70 °C

35-40°C

40-60 °C

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A pharmaceutist has to prepare 10% alcohol solution of iodine. What is the required concentration of ethanol for this purpose?

60 %

70 %

95%

40 %

96 %

‹ Назад

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Field horsetail grass is recommend as a diuretic. What herbal material can be used as a substitute?

Herba Adonidis

Herba Leonuri

Herba Aervae lanatae

Herba Convallariae

Herba Menthae piperitae

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A pharmaceutist prepares an infusion at a ratio of 1:30. What plant material would be used?

Oak bark

Lily of the valley grass

Shoots of Marsh Labrador tea

Sage leaves

Marshmallow root

‹ Назад

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Under the SPhU (appendix 2), leaves of ginkgo are standardized by the content of:

Coumarins

Saponins

Alkaloids

Flavonoids

Chromones

‹ Назад

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The pharmaceutical market is characterized by the seasonal fluctuations in demand for anticold medicines. What kind of marketing is used in case of such demand?

Conversive

Developing marketing

Remarketing

Counteractive

Synchromarketing

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Economic analysis of pharmacy activity involves a number of absolute indices. What index is determined by the formula: 'income from sales - prime cost of goods':

Gross profit

Level of costs

Total balance

Net profit

Amount of costs

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Salicylic acid and its derivatives may be the cause of acute intoxication. When salicylates are analyzed by TLC method, the chromatographic plate is sprayed with:

Dragendorff’s reagent

Solution of mercury (II) sulfate and chloroform solution

Marquis reagent

Solution of iron (III) chloride

Forrest reagent

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The simple sugar syrup consists of:

64 parts of sugar and 36 parts of water

73 parts of sugar, 22 parts of water, 5 parts of 90% alcohol

50 parts of sugar and 50 parts of water

65 parts of sugar, 33 parts of water, 2 parts of 90% alcohol

45 parts of sugar and 55 parts of water

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Prescriptions for the controlled drugs dispensed under the reimbursement program (except for the narcotic and psychotropic preparations in substance) are issued on the following prescription form:

№3 in duplicate

№1 and № 3

№1 in duplicate

№1, single copy

№3, single copy

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Quarterly evaluation of business and financial performance of a pharmacy involves calculating its profitability. For this purpose the following data is used: turnover - 100 thousands UAH, gross profit - 25 thousands UAH, expenditures -1 thousand UAH. Calculate the profitability of the pharmacy:

22 %

10 %

25 %

15%

20 %

‹ Назад

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A patient suffering from epilepsy has taken phenobarbital for a long time and developed drug tolerance. What is the mechanism of this phenomenon development?

Accumulation of substances in the body

Acceleration of biotransformation

Absorption process reduction

Receptor’s sensitivity enhancement

Inhibition of biotransformation

‹ Назад

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Who is responsible for the acceptance of goods and medical products with accompanying incoming quality control?

Authorized representative

Supplier pharmaceutist

Head of pharmacy

Analyst

Pharmaceutist

‹ Назад

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During steam distillation of voltile poisons the first portion of the distillate is collected in a receiver with 2% solution of sodium hydroxide. It is used to detect:

Cyanides

Acetates

Formaldehyde

Ethanol

Phenol

‹ Назад

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Alkaloid glaucine has an antitussive effect that is stronger and longer if compared to that of codeine, and exhibits no narcotic side effects. What drug plant contains glaucine?

Yellow hornpoppy

Henbane bell (Scopolia carniolica)

Thermopsis lanceolata

Celandine

Datura

‹ Назад

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A pharmacy has no quinquelobate motherwort in stock. It can be substituted by the following herbal material:

Linden flowers

Raspberry fruits

Rhizomes and roots of valerian

Beggarticks grass

Hypericum grass

‹ Назад

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Drug plant Dioscorea nipponica is the source for production of Polysponi-num drug which is used in the complex treatment of atherosclerosis. Specify the active compounds of dioscorea material:

Steroidal saponins

Triterpene saponins

Essential oil

Cardiac glycosides

Alkaloids

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A drug raw material from the family Polygonaceae had been sent to a laboratory for analysis. On macroscopic examination the material was identified as a herbaceous plant with lanceolate leaves with a red spot, and filmy ocreae covered with appressed hairs. The plant had the apical inflorescence in dense spicate panicles. What plant is it?

Redshank (persicaria)

Biting knotweed

Snakeweed

Common buckwheat

Common knotweed

‹ Назад

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A 35-year-old patient with tachycardia has been administered propranolol. Which of the following reactions may be caused by the use of beta-blockers?

Drug dependence

Bronchospasm

Blood pressure rise

Constipations

Cumulation

‹ Назад

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Under the SPhU requirements mercury salts are indentified by means of interaction with sodium hydroxide solution. Specify the colour of the precipitate that is produced as a resut of this reaction:

Yellow

White

Blue

Yellow-green

Red

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A 17-year-old patient complains of persistent thirst, dry mouth, frequent urination, increased appetite. Blood glucose is at the rate of 11 mmol/l. The patient has been diagnosed with diabetes melli-tus type I. What drug is indicated for treatment?

Acarbose

Maninil

Glibenclamide

Asparcamum

Insulin

‹ Назад

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A pharmacy serves the polyclinics of a city district. Specify the bill of materials that shows the number of drugs dispensed on prescriptions of the doctors who work in the polyclinics:

Outpatient

Inpatient

-

Medical

Polyclinic

‹ Назад

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At the end of the reporting period a pharmacy makes an analysis of its commercial and financial activities. What economic index describing the commercial and financial performance is defined as the ratio of the pharmacy profit to the turnover?

Profitability

Wholesale turnover

Distribution costs

Bill of material

Retail turnover

‹ Назад

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Phytochemical workshop of a factory manufactures pancreatin. What is the source material for obtaining pancreatin?

Egg white

Lungs of cattle

Heart of cattle

Pancreas of pigs or cattle

Gastric mucosa of pigs

‹ Назад

Далі ›

Which of the following diuretics SHOULD NOT be administered to patients with impaired hearing?

Spironolactone

Furosemide

Indapamide

Clopamide

Chlorthalidone

‹ Назад

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A patient who has been taking acetylsalicylic acid developed hemorrhages of mucous membranes. This phenomenon is associated with:

Inhibition of the prothrombin synthesis

Disorder of protein binding

Increased absorption in the gastrointestinal tract

Decreased absorption in the gastrointestinal tract

Changed volume of distribution

‹ Назад

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Simultaneous use of paracetamol and acetylcysteine causes:

Reduction of anti-inflammatory action of paracetamol

Increase of paracetamol nephrotoxicity

Reduction of paracetamol hepatotoxi-city

Inhibition of paracetamol absorption

Increase of mucolytic action of acetylcysteine

‹ Назад

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Simultaneous use of gentamicin and acyclovir tablets increases the risk of:

Nephrotoxicity

Cardiotoxicity

Likelihood of allergic reactions

Hepatotoxicity

Neurotoxicity

‹ Назад

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Simultaneous use of doxycycline hydrochloride and oral contraceptive causes:

Increase of oral contraceptives effectiveness

Reduction of the antibacterial effect of doxycycline

Reduction of oral contraceptives effectiveness

-

Increase of the antibacterial effect of doxycycline

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In case of simultaneous use of metronidazole and oral anticoagulants derived from coumarin patients must be warned about:

Potentiation of anticoagulants effect and the risk of bleeding

Higher neurotoxicity

Reduction of anticoagulants effect

Potentiation of metronidazole effect

Reduction of metronidazole effect

‹ Назад

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Business transactions of pharmacies are reported in the accounts. Specify the account that reports the settlements with debtors and creditors:

Nominal

Business

Positive

Negative

Trial balance

‹ Назад

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Apart from goods sales, there are other business transactions that can be characterized as goods disposal. Which of the following business transactions reduces the stock at pharmacies?

Reclassifying other supplies as goods

Bringing the glassware on charge

Disposal of products for economic needs

Revaluation for the packing and laboratory work

Bringing the oversupply on charge

‹ Назад

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A pharmaceutical analyst analyzes the substance of ascorbic acid in compliance with the requirements of the State Pharmacopoeia of Ukraine. To identify the oxalic acid impurities he uses the solution of:

Sodium hydrocarbonate

Sodium thiosulfate

Sodium chloride

Calcium chloride

Sodium sulfate

‹ Назад

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Phenobarbital drug has a sedative, hypnotic and anti-epileptic effect. What is its international nonproprietary name?

Nitrofurazone

Luminal

Chloramphenicol

Salol

Diazepam

‹ Назад

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A 70-year-old patient with stenocardia claims that the pharmacy sold him a drug that relieved an attack of stenocardia but instead caused an acute bursting headache. What antihypertensive drug is this side effect typical for?

Nitrosorbid

Nifedipine

Amlodipine

Metoprolol

Trimetazidine

‹ Назад

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During the working day a pharmaceutist prepared five dosage forms. Which of them requires a complete chemical control?

5 % aethonium solution

Ear drops with levomycitin

Mixtura Pavlovi

Eye drops 10 ml of 2% ethylmorphine hydrochloride solution

Antipruritic ointment

‹ Назад

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Commercial and financial activity of a pharmacy involves using returnable tare. Which of the following containers are returned to the supplier?

Paper boxes

Packaging materials

Metal cylinders

Glassware

Glass-stoppered bottles

‹ Назад

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A pharmacy plans to expand the production of medicines. For this purpose it purchased the production equipment at a cost of 7000 uAh. The cost of the equipment will be recorded to the balance of the pharmacy as:

Residual

Fair value

Revalued amount

Amortization cost

Initial cost

‹ Назад

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An accountant of a pharmacy issued a cash receipt voucher for the sales proceeds. What document is used to register cash receipt and cash payment vouchers before the cash arrives to the cashiers?

Pay list

Cash report

Ledger of cash dispensed and received by the senior teller

Register of receipt and payment cash documents

Cash book

‹ Назад

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Biochemical blood test revealed low level of serum iron. What disease are these changes typical for?

Bronchiectasis

Acute bronchitis

Pneumonia

Iron-deficiency anemia

Bronchial asthma

‹ Назад

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A patient who has been treated for hypertension complains of cough. Objective examination reveals no changes in the lungs. Which of the following drugs might have caused cough?

Hypothiazide

Amlodipine

Captopril

Nebivolol

Clonidine

‹ Назад

Далі ›

What non-narcotic antitussive drug of central action can be used for dry cough?

Acetylcysteine

Mucaltin

Glaucine

Ambroxol

Codeine

‹ Назад

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Galenic preparations are produced by using various extractants. What extractants require pressure as a prior condition for the extraction process?

Dichloroethane, chloroform

Ethanol

Vegetable oils

Liquefied gases

Methyl alcohol, acetone

‹ Назад

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Menthol has anesthetic and antiseptic effect. What plant is the source of menthol?

Folia Uvae ursi

Folia Salviae

Folia Menthae piperitae

Folia Eucalypti

Folia Absinthii

‹ Назад

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Hydrocyanic acid and its salts are extremely toxic substances. In humans, they are partly neutralized by enzymatic conversion into:

Nitrogen (II) oxide

Carbon (IV) oxide

Acetic acid

Ethanol

Thiocyanate

‹ Назад

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Methyl alcohol which is widely used in industry causes severe health disorders when enters the human body even in small amounts. This effect is induced by the action of the following major metabolites of methanol:

Acetic acid and acetaldehyde

Ethanol and acetaldehyde

Methyl acetate and ethyl acetate

Ethyl alcohol and ethyl acetate

Formaldehyde and formate acid

‹ Назад

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Enrolled in private pharmacies to implement a drug whose active ingredient is the chemical name of 2-chloro-10-(3’-dimethylaminopropyl)-phenothiazine hydrochloride. Specify this drug:

Chlorpromazine hydrochloride

Clonidine hydrochloride

Trifluoperazine hydrochloride

Diphenhydramine hydrochloride

Promethazine hydrochloride

‹ Назад

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The thyme grass is used for the production of herbal medical products for the treatment of respiratory tract infections. Under the SPhU, the herbal raw material is subject to chromatographic identification by means of thin layer chromatography. What substances are detected on the chromatographic plate after its treatment with due reagent?

Apigenin and luteolin

Thymol and carvacrol

Quercetin and rutin

Arbutin and methyl arbutin

Atropine and hyoscyamine

‹ Назад

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Flower buds of clove contain the essential oil used for production of herbal antiseptics. Under the State Pharmacopoeia of Ukraine, the raw materials are identified by the method of thin layer chromatography. What zones can be identified on the chromatographic plate after their treatment with reagent?

Apigenin and luteolin

Quercetin and rutin

Eugenol and caryophyllene

Hyoscyamine and scopolamine

Scopoletin and umbeliferon

‹ Назад

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Specify the base for the preparation of antibiotic ointments:

5 parts of vaseline + 5 part of lanolin

7 parts of vaseline + 3 part of lanolin

8 parts of vaseline + 2 part of lanolin

6 parts of vaseline + 4 part of lanolin

5 parts of vaseline + 1 part of lanolin

‹ Назад

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Business transactions of a pharmacy are recorded in the control accounts as listed in the chart of accounts. The balance on the ledger and sub-ledger accounts is used to fill out the following document:

Profit and loss account

Fourth section of the liabilities side

First section of the liabilities side

Assets

Liabilities

‹ Назад

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A 40-year-old patient has a history of bronchial asthma and heart rhythm disorders in form of bradyarrhythmias. Bronchospasm can be eliminated by the drugs of the following pharmacological group:

M-cholinomimetics

в-blockers

M-cholinergic antagonists

Cholinesterase inhibitors

Muscle relaxants

‹ Назад

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