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A pharmaceutist prepared powders including extract of belladonna in the amount of 0,015 per dose. For ten doses he had to take the following amount of dry extract:
0,3 g
0,03 g
0,15 g
1,5 g
0,015 g
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A pharmaceutical company focuses on selling a diverse range of products covering different customer groups and regions. What kind of organizational structure is typical for such company?
Centralized
Functional
Bureaucratic
Divisional
Decentralized
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A pharmaceutical company produces cordiamin solution. During the quality control its quantitative content was determined by means of refractometry. For this purpose an analytical chemist measured:
Density
Index of refraction
Viscosity
Angle of rotation
Intensity of absorption
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Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?
Phenylinum
Acetylsalicylic acid
Streptokinase
Heparin
Ticlopidine
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On the 4th day of treatment with indomethacin a 55-year-old patient developed gastric bleeding as a result of ulceration of the gastric mucosa. Ulcerogenic effect of this drug is due to a decrease in activity of the following enzyme:
Cyclooxygenase-2 (COX-2)
Prostacyclin synthetase
Thromboxane synthetase
Lipoxygenase (LOX)
Cyclooxygenase-1 (COX-1)
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A patient complaining of dry mouth, photophobia and blurred vision has been delivered to the admission ward. Objectively: the skin is hyperaemic, dry; mydriatic pupils and tachycardia are present. He has been diagnosed with belladonna alkaloids intoxication. Which of the drugs should be given as an antidote?
Aceclidine
Neostigmine
Arminum
Dipiroximum
Pylocarpine
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To stop the delusions and hallucinations in a schizophrenic patient a doctor administered aminazine. What is the mechanism of antihypoxic action of this drug?
Stimulation of adrenergic and dopaminergic processes in the CNS
Inhibition of dopaminergic processes in the CNS
Stimulation of cholinergic processes in the CNS
Inhibition of adrenergic processes in the CNS
Inhibition of cholinergic processes in the CNS
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During a surgical operation the muscle relaxant tubocurarine chloride was used. What antagonist drug should be injected in order to allow the patient to breathe independently?
Dithylinum
Aethimizolum
Cytitonum
Веnzohexonium
Neostigmine
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A patient came to a drugstore and ordered cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?
Folium Uvae ursi
Herba Achilleae millefolii
Rizoma Calami
Rizoma et radix Sanquisorbae officinalis
Radix Taraxaci officinalis
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A pharmaceutist has prepared a tincture of althaea root. What is the proportion of herbal raw material and extractant?
1:30
1:10
1:100
1:20
1:400
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An analytical chemist working at a pharmacy identifies oxacillin sodium salt. As a reagent he uses hydroxylami-ne hydrochloride solution in presence of sodium hydroxide solution and copper nitrate solution. What structural fragment of a drug molecule can be detected by means of these reagents?
Furan cycle
Thiazolidine cycle
Beta-lactam cycle
Thiadiazole cycle
Isoxazole cycle
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Diethyl ether relates to simple ethers. Prior to its identification by using the boiling temperature an analytical chemist must ensure that there are no:
Peroxides
Alcohols
Non-volatile residue
Carboxylic acids
Reducing substances
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In order to detect peroxides in the anesthetic ether an analytical chemist should use the following reagent:
Potassium chloride
Sodium hydroxide
Potassium permanganate
Sodium thiosulfate
Potassium iodide
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A syrup contains 82 parts of sugar syrup; 1 part of KJ (KBr); 12 parts of liquid thyme extract and 5 parts of 96% ethanol. What is this medicine called?
Cholosasum
Pertussinum
Ambroxol
Broncholytin
Licorice syrup
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A pharmaceutical enterprise that has achieved high sales rates and customers’ recognition will reach the highest profit at the following stage of the product life cycle:
Development
Decrease
Maturity
Growth
Market penetration
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A pharmaceutic plant producing ointments can use the following equipment at the packing stage:
Eccentric machines
Screw and piston dosing machines
Disc machines
Rotary machines
Rezepin automatic machine
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Aerosol workshop of a pharmaceutic plant uses propellents of different groups. What propellents relate to the group of compressed gases?
Vinyl and methyl chloride
Freons
Nitrogen, nitrous oxide, carbon dioxide
Propane, butane, isobutane
Methylene chloride, ethylene chloride
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An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?
Bromatometry
Mercurimetric determination
Nitritometric determination
Iodometry
Chelatometry
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Which preparation is the specific antidote in case of intoxication with iron preparations?
Bemegridum
Protamine sulfate
Penicillamine
Atropinum
Deferoxamium
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A pharmaceutist prepared solution of ethacrydine lactate. What is the peculiarity of this substance dissolving?
Grinding in a mortar with water
Dissolving in potassium iodide solution
Dissolving in hot water
Dissolving in cold water
Dissolving in freshly distilled water
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A pharmacy produces compounded drugs. What kinds of internal control of drugs production are required?
Written, qualitative and quantitative analysis
Written, interrogatory, sell control
Written, physics and chemical
Written, organoleptic, sell control
Written and sell control
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A pharmacy analyst can verify presence of iron cation (II) in a drug formulation by means of the following solution:
Potassium bromide
Magnesium sulfate
Sodium phosphate
Ammonium sulfide
Sodium chloride
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A pregnant woman fell ill with severe pneumonia. Which of these antimicrobials should be administered to this patient?
Cefotaxime
Ofloxacin
Tetracycline hydrochloride
Gentamicin sulfate
Biseptol
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A pharmacy manager is working out a schedule for a pharmaceutist who is responsible for prescription reception and drug serving out. What is the weekly working time for one employee?
30 hours
36 hours
40 hours
38 hours
Irregular working week
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A pharmaceutist was on a business trip. What is the deadline for submitting a travel expense report?
Four working days after returning from a trip
Three working days after returning from a trip
There is no deadline
Ten working days after returning from a trip
A week after returning from a trip
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An advance holder (accountant) was given some money from the cash fund of an enterprise for purchase of office accessories. After the cash advance the advance holder must submit the complete application of funds statement no later than:
Ten working days
Third banking day
Such term isn’t established
One week
Five working days
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A pharmacy selling officinal drugs is a successful participant of the pharmaceutical market. Specify the business transaction which is qualified as pharmacy revenue:
Writing-off of the cost of goods sold
Receipt of advance payment made by a customer
Proceeds of a structural subdivision of a pharmacy
Salary accounting
Tax charge
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A pharmacy provides its customers with officinal medicines. Specify the business transaction which is qualified as pharmacy expenses:
Personal income tax
Proceeds of a structural subdivision
Write-off of cost of goods sold
Pharmacy proceeds
Posting of goods
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Medicinal plant Rhamnus cathartica is used as a laxative. What part of this plant is used as herbal raw material?
Leaves
Rind
Roots
Fruits
Shoots
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When the glucose is heated with the copper-tartrate reagent (Fehling’s reagent) the brick-red precipitate settles down. It indicates presence of the following group:
Etherific
Amide
Ketonic
Carboxyl
Aldehyde
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For the purpose of sales stimulation a pharmaceutical wholesale company grants its customers a discount according to the social contract and on condition of their loyalty. Specify the type of discount:
Bonus
Dealer
-
Discounts for quantity of purchased goods
Seasonal
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Before accepting the goods by a pharmacy, they should be checked for quantity and quality. If there is no discrepancy, the pharmacy issues a warrant for receipt of goods. This warrant is valid for:
1 year
15 days
10 days
20 days
3 months
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A patient got intoxicated with an unknown substance. Test of biological material revealed pH=2,0-3,0. The chemico-toxicological analysis should be carried out for the following group of substances:
Alkali metal salts
Alkalis
Weak organic acids and heavy metal salts
Ammonia
Mineral acids or large amounts of organic acids
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One of the quality indicators for finished ampoules is lack of residual stress in the glass. Which operation at the stage 'Preparation of ampoules to be fi-lled'eliminates this imperfection?
Ampoule annealing
Ampoule drying
Capillary opening
Ampoule washing
Ampoule sterilization
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Companies producing injectable dosage forms apply different methods of ampoule sealing. Sealing against a jet of inert gases (nitrogen, argon, carbon dioxide) is suitable for the following injection solutions:
Hydrolytically unstable
Viscous
Photosensitive
Thermostable
Easily oxidable
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Quality control of tablets produced at a pharmaceutical enterprise involves quantitative determination of such subsidiary substances as talc and aerosil. What method is applied for such determination?
Chromatographic
Gravimetric
Titrimetric
Photocolorimetric
Spectrophotometric
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A 6-year-old child with pneumonia has been administered an antibiotic. After treatment the child lost his hearing. What group of antibiotics might have caused this complication?
Semi-synthetic penicillins
Aminoglycosides
Cephalosporins
Macrolides
Natural penicillins
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A 52-year-old patient had myocardial infarction and was discharged from the hospital after the stationery treatment. What daily dose of acetylsalicylic acid should be administered in order to prevent thrombosis?
1000 mg
100 mg
500 mg
200 mg
50 mg
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A woman died from pesticide poisoning as a result of processing of agricultural crops. Measurement of organophosphorous compounds in the extracts of biological material should be started with the following test:
Test for the presence of chlorine atom
Test for the phosphate ion
Test for the presence of a sulfur atom
Biochemical assay
Test for methoxy or ethoxy groups
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In the medical practice this compound is used as a disinfectant. In case of intoxication with this compound the patient’s urine turns olive or olive-black. Specify the compound:
Ethyl ether
Iodoform
Ethyl benzoate
Isoamyl alcohol
Phenol
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In order to identify a drug an analytical chemist of the State Inspectorate for Quality Control of Medicines carries out the reaction with ninhydrin solution. Specify the drug to be identified:
Ascorbic acid
Cortisone acetate
Paracetamol
Methionine
Streptocide
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A pharmaceutist prepared suppository mass with novocaine and cocoa butter, but it turned out to be crumbling. What substance to be added to form a plastic mass:
Hydrous lanolin
Paraffin
Wax
Vaseline
Anhydrous lanolin
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A pharmaceutist has to sterilize 400 ml of calcium gluconate solution for injections. Specify the time of autoclave sterilization of the solution at 120°C:
30 minutes
10 minutes
15 minutes
20 minutes
12 minutes
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Anesthesin relates to substances with local anesthetic activity and is a derivative of the following acid:
Para-aminobenzolsulfonic
Para-chlorbenzoic
Para-aminobenzoic
Para-aminophthalic
Para-aminosalicylic
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According to the State Pharmacopoeia of Ukraine, in order to test a substance for the highest level of magnesium impurities an analytical chemist must use the following solution:
Resorcin
Formaldehyde
Hydroxyquinoline
Benzaldehyde
Pyridine
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Select a reagent that should be applied by an analytical chemist in order to detect alkaloids in the herbal raw material:
Dragendorff reagent
Alkaline solution
Stahl’s reagent
Bromine water
Trim-Hill reagent
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Preparations of sorrel roots can have both a laxative and astringent effect. This is due to the presence of the following biologically active substances:
Flavonoids and essential oils
Iridoids and vitamins
Essential and fatty oils
Coumarins and phenol glycosides
Anthracene derivatives and tannins
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Emodin, an anthracene derivative, haspurgative effect. Large quantities of anthracene-derived groups of emodin are contained in the fruits of the following plant:
Alder buckthorn (Frangula alnus)
Blackcurrant
Buckthorn
Blueberry (Vaccinium myrtillus)
Elder (Sambucus)
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A pharmacy manager is writing the monthly 'Inventory report'. What business transactions should be represented in the expenditure item of the report?
Drug sales
Payroll payment
Herbal raw material purchases
Amortization charged to operation
Extra-evaluation of laboratorypackaging works
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A pharmacy has a license for selling narcotic drugs. The warrant for the receipt of these drugs from the pharmacy warehouse is valid for:
No longer than 1 calendar days from the date of issue
No longer than 1 year from the date of issue
No longer than 3 months from the date of issue
No longer than 10 calendar days from the date of issue
No longer than 5 calendar days from the date of issue
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Which of the pharmacy departments is responsible for checking the quantity and quality of received goods, their storage and dispensing to other departments?
Department of curative cosmetics
Compounding and production department
Department of over-the-counter drugs
Inventory department
Department of finished dosage forms
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The possible admixture in the crop of raw coltsfoot leaves (Tussilago farfara) is the leaf of:
Nettle
Common plantain
Primula officinalis
Marshmallow (Althaea officinalis)
Cotton burdock (Arctium tomentosum)
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In order to determine the purity a drop of lavender essential oil was applied on a strip of filter paper and warmed up in the stream of warm air. Some time later the stain increased in diameter. What impuri- ty substance was found in the lavender oil?
Ethanol
Acetone
Diethyl ether
Fatty or mineral oil
Phenol
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A pharmacy received a batch of raw material - chamomile flowers. How should this material be stored?
In a light room
According to the list B requirements
According to the list A requirements
Separately from all other kinds of raw material
As a narcotic raw material
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A patient acquired mint leaves at a pharmacy. What recommendations regarding infusion of this herbal raw material must be given by the pharmaceutist?
The extract is to be immediately filtered after infusing
The extract is to be artificially cooled 15 minutes after infusing
The infusion is to be prepared in a tightly closed vessel
The infusion is to be prepared at room temperature
The infusion is to be prepared on an open fire
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A patient has been administered a solution containing boric acid and camphor. What solvent should his doctor prescribe in order to prevent physical incompatibility?
Sunflower oil
Glycerol
Ethyl alcohol 40%
Ethyl alcohol 70%
Purified water
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A patient has chronic pancreatitis with apparent presentations of pancreatic exocrine hypofunction. Which of the following drugs would be the most appropriate in this case?
Acidin pepsinum
Drotaverine
Раncreatinum
Dе-Nоl
Оmерrаzоlе
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A patient got an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient has presented with red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucous membrane. What is the cause of this complication?
Abstinence syndrome
Delayed allergy
Tachyphylaxis
Local irritation
Immediate allergy
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A 15-year-old patient has been first diagnosed with type I diabetes mellitus. Which antihyperglycemic drug should be administered in this case?
Glibenclamide
Metformin
Glurenorm
Diabetone
Insulin
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A patient with gastric ulcer has been administered omeprazole. What is its mechanism of action?
Inhibition of H+K+-ATPase
Blockade of histamine H2 receptors
HCl neutralization
Blockade of M-cholinergic receptors
Stimulation of mucus production
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A manufacturing company initiates changes to the package insert of a drug aimed at limitation of its use. What type of marketing is used by the company in this case?
Remarketing
Counteractive
Conversion
Synchromarketing
Stimulating
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When developing a new drug a manufacturer may apply different strategies of brand use. If a company uses one brand name for all of its products, such strategy is called:
Multi-brand approach
The combination of brand name with an individual drug brand
Brands for individual drugs
Group brands
Individual brands
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A doctor prescribed his patient an emulsion of olive oil which includes anesthesin. To incorporate anesthesin into the emulsion it must be dissolved:
In the alcohol, and then added to the primary emulsion
In oil before preparing the emulsion
In the primary emulsion
In the purified water
In the finished emulsion
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The patient has been prescribed Lini-mentum Rosentali. It is composed of:
Chloroform, methyl salicylate, turpentine
Paraffin, alcohol, chloroform, iodine
Castor oil, calcium chloride, alcohol
Iodine, potassium chloride, glycerin
Sunflower oil, ammonia, oleic acid
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Injection solutions of salts derived from weak acids and strong bases require stabilization. What stabilizers are used for these solutions?
Buthylhydroxytoluene
Ascorbic acid
0,1 M sodium hydroxide solution
0,1 M acid chloride solution
Trilon B
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A pharmaceutical plant produces suppositories. What is the best method for their manufacturing in industrial quantities?
Lyophilization
Pressing
Pumping-out
Outpouring
Stamping
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О-methylation is an important way of biotransformation of organic substances in the body. Compounds subject to О-methylation should contain:
Phenol groups
Amino groups
Carboxyl groups
Nitro groups
Thiol groups
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A pharmaceutist prepares a suspension ointment. What substance is soluble in water, but should be incorporated into the dermatological ointments as a suspension?
Furacilin
Resorcinol
Potassium iodide
Zinc oxide
Sulfacyl sodium
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It is necessary to analyze herbal raw material in form of black glossy drupes 6-8 mm in diameter, with a large, firm, globular, light brown kernel containing one seed. The drupes have sweet and slightly astringent taste. This herbal raw material should be identified as fruits of:
Black chokeberry
Hawthorn
Blueberry
Buckthorn
Bird cherry
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Method of gas-liquid chromatography is often applied for identification and quantitative determination of toxicologically meaningful substances. Substances can be placed into the chromatograph dispenser in the following aggregate states:
Liquid
Liquid and solid
Gaseous and solid
Liquid and gaseous
Gaseous
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Which of the following non-steroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?
Nimesulide
Piroxicam
Acetylsalicylic acid
Indomethacin
Diclofenac
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Which drug is used for thrombolysis in case of acute myocardial infarction?
Acetylsalicylic acid
Pentoxifylline
Alteplase
Fraxiparine
Heparin
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When doing calculations to determine the limit of the cash balance, an accountant must specify the actual amount of cash receipts. What time period should be taken into account?
7 days prior to calculation
Three months prior to calculation
1 year prior to calculation
Six months prior to calculation
10 days prior to calculation
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A doctor gave a prescription for the tincture of digitalis with hydrochloric acid. What is the reason for their incompatibility?
Hydrolysis (with no visible changes)
Gassing
Precipitation
Change in odour
Change in colour
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At the initial stage of establishing a pharmaceutical enterprise the internal disciplinary regulations should be adopted. One of the primary matters is the duration of the lunch break for the employees. According to the Labour Code of Ukraine, the break duration must be as follows:
2,5 hours
Up to 2 hours
Not less than 3 hours
-
Up to 1 hour
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A woman asked a pharmaceutist to dispense an antipyretic for an 8-month-old child. Which drug should be recommended?
Diclofenac sodium
Indomethacin
Paracetamol
Acetylsalicylic acid
Piroxicam
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A 70-year-old patient consulted a doctor about elevated arterial pressure. He has a history of benign hyperplasia of prostate. What drug should be administered in this case?
Diltiazem
Losartan
Ем^ні
Propranolol
Doxazosin
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Having ascertained that the quality of raw material meets the requirements of the analytical normative documentation the quality control department should issue a document. Specify this document:
Standard
Pharmacopoeia entry
Certificate of analysis
Order
Request
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A pharmaceutist revealed incompatibility in a prescription for powders with ascorbic acid and hexamethylene tetrami-ne. What process takes place when these components are combined?
Mixture dampening
Adsorption
Eutectic
Isolation of crystallization water
Immiscibility
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Efficiency of aerosol therapy is to a considerable extent determined by the size of disperse particles. What factor determines the size of aerosol particles during dispersion of an aerosol?
Percentage of phase, filling temperature
Exit port diameter, propellent vapour pressure
System homogeneity, dispersion velocity
Reduction range, container quantity
Fractional composition, containers filling method
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Prior hydrolysis is necessary in case of quantitative determination of the following drug by the nitritometric titration:
Anesthesin
Procaine hydrochloride
Paracetamol
Dicaine
Sodium p-aminosalicylate
‹ Назад
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A pharmacy plans to purchase and retail goods of different stock record units. Which group of goods does VAT reduction apply to?
Perfumes
Curative cosmetics
Baby food
Medicaments
Optics
‹ Назад
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An analytical chemist determines the admixture of sulphates in the boric acid. What is the main reagent to be added?
Sodium sulphide
Barium chloride
Silver nitrate
Potassium ferrocyanide
Ammonium oxalate
‹ Назад
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Recommend a patient with acute bronchitis a mucolytic drug that facilitates expectoration:
Drotaverine hydrochloride
Glaucine
Acetylcysteine
Diclofenac sodium
Loratadine
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A patient with atopic dermatitis presented at the hospital. Which drug with anti-inflammatory and antiallergic effect should be administered to this patient?
Insulin
Prednisolone
Retabolil
Aethamidum
Oxytocin
‹ Назад
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A patient with atherosclerosis has been administered an anti-atherosclerotic agent. Specify this drug:
Phenylbutazone
Dexamethasone
Ascorbic acid
Phenofibrate
Pyracetam
‹ Назад
Далі ›
A patient after bee’s stings has angi-oedema (Quincke’s edema). Which drug should be immediately inject to eliminate this condition?
Sodium chloride
Epinephrine hydrochloride
Anaprilinum
Atropine sulfate
Platyphyllini hydrotartras
‹ Назад
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A pharmacy received a batch of medicines from a pharmacy depot. Specify the drug subject to the controlled substance inventory in pharmacies:
Dicaine
Acetylsalicylic acid
Analgin
Novocaine
Paracetamol
‹ Назад
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A pharmaceutical company conducted an age-specific segment analysis of the regional antihistamine market. It revealed the lack of antihistamines for children. The company will consider this segment as:
Unattractive segment
Market door
Market niche
Market share
Segment requiring further research
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The manufacturing pharmaceutical company 'Elema'set up its own corporate pharmacy. In this case, it uses the following distribution channel:
Fourth level
First level
Zero level
Second level
Third level
‹ Назад
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A pharmacy received some medicines from the warehouse. What medicine is subject to the stocktaking in the pharmaceutical institutions?
Aminalonum
Butadionum
Analginum
Corvalolum
Codeine
‹ Назад
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A pharmacy sells drugs by retail. Omnopon relates to the following group of controlled drugs:
General sale list
Psychtropic
Narcotic
Potent
Toxic
‹ Назад
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A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:
Mefenamic acid
Acetylsalicylic acid
Ursodeoxycholic acid
Gamma-aminobutyric acid
Citric acid
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A patient with acute heart failure and intolerance of cardiac glycosides has been given an injection of dobutamine. What is the mechanism of its action?
Stimulation of M-cholinergic receptors
Stimulation of β₁-adrenoceptors
Blockade of K+-, Na+-ATPase
Stimulation of α- adrenoceptors
Inhibition of phosphodiesterase
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One of the methods of quantitative analysis of active substances in the raw material is the biological standardization. It can be applied with the following group of biologically active substances:
Fatty oils
Alkaloids
Tannins
Cardiac gliycosides
Mucilages
‹ Назад
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In the process of pressing the tablets adhere to the pressing tool. The technological error is the lack of:
Disintegrants
Diluents
Dyes
Lubricants
Adhesive substances
‹ Назад
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An elderly patient has constipation caused by hypotonia of colon. What drug should be administered to this patient?
Atropine sulfate
Novocaine amide
Castor oil
Bisacodyl
Sodium sulfate
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A forensic medicine laboratory received some biological material. It should be analyzed for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:
Ethanol acidified with oxalic acid
Chloroform
Propanol acidified with oxalic acid
Water alkalized with ammonia solution
Water acidified with sulfuric acid
‹ Назад
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A chemical department produces alcohol solution of boric acid. What filters are used for filtration of this solution?
Nutsch filter
Paper filter
Pressure filters
Bag filter
Membrane filter
‹ Назад
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A pharmacy received a prescription for preparation of dermatological ointment with benzylpenicillin. Specify the type of ointment that necessary to prepare:
Suspension ointment
Combined
Hydrophilic ointment
Liquid ointment
Alloy ointment
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Далі ›
A pharmacy received a prescription for powders with doctor’s instruction to dispense powders in gelatin capsules. Which of the following substances is included in the composition of these powders?
Streptocide
Magnesium oxide
Ethacridine lactate
Glucose
Diphenhydramine
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Далі ›
In course of pharmacotherapy of bronchitis a patient was found to have dyspeptic disorders, photodermatitis, liver dysfunction. Which of the prescribed drugs might have caused these manifestations?
Ascorbic acid
Paracetamolum
Doxycyclin
Codeine phosphate
Acetylcysteinum
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From the pharmaceutical stock select an anticholinesterase drug to be administered to the patients with atony of the intestine and urinary bladder in the postoperative period:
Atropine sulfate
Dithylinum
Phosphacolum
Benzohexonium
Proserin
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Most alkaloids are isolated from the biological material by means of polar solvents. Which of the listed alkaloids is isolated by the way of distillation with water vapour?
Coniine
Strychnine
Atropine
Cocaine
Quinine
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Comparative analysis of the performance of two pharmacies showed that the trade stock in terms of days was 20 and 30 days respectively. Which of these indicators is NOT USED for calculating the trade stock?
The left-over goods in terms of settlement prices
Wage fund
Turnover
Sales volume
The rate of trade mark-up
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A pharmacy received a batch of drugs from a wholesale firm. What document signed by an authorized person is the basis for further sale of drugs?
National register of medicinal products
Quality certificates
Register of medicinal products accepted for sale
Opinion letter of the territorial inspectorate
Information on state registration
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A patient who has been suffering from gastric diseases for a long time is found to have hyperchromic anemia. Which of the following drugs is applied for this pathology treatment?
Ascorbic acid
Ferrum Lek
Unitiol
Охуferriscorbone
Cyanocobalamine
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A phytopreparation 'Flacarbi-num'has spasmolytic, anti-inflammatory and antiulcer effect. This preparation is produced out of the following plant:
Jacob’s ladder blue (Polemonium caeruleum)
Licorice (Glycyrrhiza)
Buckeye (Aesculus)
Pot marigold (Calendula officinalis)
Mountain angelica (Aralia mandshuri-ca)
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Specify the reaction to the ester-type drugs that is tolerated by the State Pharmacopoeia of Ukraine:
Formation of 3-bromphenol
Formation of azo dye
Formation of iron hydroxamates
-
Formation of indophenol
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Streptocide, sulfacyl sodium, norsulfazole or sulfadimezinum can be identified by means of the reaction to form:
Fluorescein
Iodoform
-
Azo dye
Murexide
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Which of the following drugs can be quantified by an analytical chemist by ceriometry method?
Acetylsalicylic acid
Sodium benzoate
Vicasolum
Phenobarbital
Phenyl salycylate
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Three founders set up a business entity for the wholesale distribution of medicines and healthcare products. Specify the form of such company:
Public
Utility
Corporate
Individual
Unitary
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Pharmaceutical market is in such a situation when there is only one company selling a certain product. Specify the competitive structure of the market:
Monopolistic competitive market
Pure competition market
Pure monopoly market and oligopolistic market
Pure monopoly market
Oligopolistic market
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The founders are going to open a retail pharmacy. What way of business running is stipulated in this case?
Free
Limited
Licence-based
Without preliminary licencing or registration
Normative
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A pharmaceutist prepared 150 ml of Adonis vernalis infusion using dry extract concentrate [1:1] that had to be weighed in the amount of :
10, 0
15, 0
5,0
7, 5
22, 5
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A pharmacy received a prescription: Rp.: Dibazoli0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose :
0, 30
2, 7
0, 25
0, 26
0,27
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An analytical chemist determines the quantity of a drug by the method of indirect bromatometry. Which of the following titrated solutions is to be used?
Sodium thiosulfate
Silver nitrate
Calcium bromate
Sodium nitrite
Sodium edetate
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In order to identify a drug an analytical chemist of the State Inspectorate for Quality Control performs a lignin test. Specify this drug:
Analgin
Ascorbic acid
Streptocid
Cortisone acetate
Methionine
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The main active components of hawthorn berries are flavonoids. What is their pharmacological effect?
Antispasmodic and anti-inflammatory
Tonic and antispasmodic
Laxative and sedative
Hypotensive and sedative
Diuretic and styptic
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An analytical chemist working at an analytical laboratory identifies a drug by the sulfite ions according to the requirements of the State Pharmacopoeia of Ukraine. What reagent gets decolorized during this assay?
Iron (III) chloride solution
Potassium nitrate solution
Iodine solution
Potassium iodide solution
Ammonia solution
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An analytical laboratory received 'Aether anaestheticus' for analysis. What reagent should be used for detecting acetone and aldehyde impurities according to the State Pharmacopoeia of Ukraine?
Hydroxylamine solution
Aqueous solution of potassium iodide
Ammonium solution of argentum nitrate
Alkaline solution of potassium tetrai-odomercurate
Sodium hydrosulfite solution
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Compulsory deductions from employee’s salary are made by the accounting department independently. Specify a deduction which can be made only on the grounds of written permit of an employee:
Contributions to the Social insurance fund for unemployment
Superannuation contributions
Alimony
Charitable contributions
Contributions to the Social insurance fund for temporary disability
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Natural persons registered as small business entities with simplified taxation scheme (2 group) have the limit for the annual amount of sales proceeds. Specify the proceeds limit:
5 million UAH
750 thousand UAH
3 million UAH
1 million UAH
100 thousand UAH
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Fatty oil containing unsaturated fatty acids is used for the prevention of atherosclerosis. Specify the herbal raw material used for oil production:
Seeds of fennelflower
Fruits of dill
Fruits of black chokeberry
Hawthorn berries
Seeds of flax
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The ampoule workshop produces solutions for injections. The aminophylli-ne solution for injections relates to the following group of solutions:
Solutions of salts composed of weak bases and strong acids
Solutions of substances requiring special purification
Solutions of salts composed of strong bases and weak acids
Solutions are not subject to heat sterilization
Solutions of easily oxidizable substances
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Phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different raw materials. Specify the biogenic stimulators of animal origin:
Peloidinum, humisolum, torfotum, plasmolum, solcoseryl
Liquid aloe extract, aloe liniment, aloe juice, biossedum
Vitreous body, placental suspension for injections, plasmolum, solcoseryl
Peloidinum, humisolum, torfotum, Fibs pro injectionibus
Liquid aloe extract, aloe liniment, plasmolum
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The planning of marketing strategy involves two successive stages. What are the stages of the strategic planning process?
Developing a program of activities
Defining the mission and goals of a pharmaceutical company
Budgeting
Describing the current marketing situation
Making the list of tasks and problems
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Benzathine benzylpenicillin is the drug of choice for treating the following disease:
Furunculosis
Intestinal infection
Syphilis
Pneumonia
Angina
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In order to identify ouabain (strophanthine G), a drug from the group of cardiac glycosides, an analytical chemist must prove the presence of a steroid cycle. What acid should be used as a reagent?
Formic
Oxalic
Sulfuric
Chromotropic
Citric
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An analytical laboratory has to analyze ferrous sulfate heptahydrate according to the State Pharmacopoeia of Ukraine. A test portion of the substance should be titrated with the following solution:
Silver nitrate
Ammonium cerium sulfate
Sodium edetate
Potassium bromate
Ammonium thiocyanate
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Urine of an intoxicated person was found to contain ecgonine. This indicates poisoning with the following substance:
Cocaine
Caffeine
Phenol
Heroin
Phenacetin
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A patient with schizophrenia has been administered a neuroleptic. Which of the listed drugs falls into this group?
Morphine
Celecoxib
Pyracetam
Aminazine
Propranolol
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A laboratory received some herbal raw material for analysis. It is a composition of ovoidpointed leaves up to 25 cm long and 20 cm wide; the leaf base is cuneate, the leaf edge is emarginate, The cutting is long and cylindric. The leaf venation is pinnatisect; the midrib and the first-order veins project significantly on the inferior surface of the leaf. The superior leaf surface is dark green, the inferior surface is light green. The plant has a weak narcotic smell. The taste cannot be determined. The plant is poisonous! The described herbal raw material relates to the following plant:
Vinca minor
Chelidonium majus
Datura stramonium
Passiflora incarnata
-
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A pharmaceutist has prepared an emulsion. Specify the way of incorporation of the fat-soluble substances:
They are added to the emulsifier
They are dissolved in oil
They are dissolved in purified water
They are added to the finished emulsion
They are incorporated in undissolved form
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A pharmacy received a prescription for a mixture. What drug substances are incompatible?
Papaverine hydrochloride + ami-nophylline
Codeine phosphate + extract of Thermopsis
Sodium bromide + sodium chloride
Novocaine + diphenhydramine
Phenobarbital + glucose
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The risk can arise from some forms of activity connected with production of goods and services, their selling, commodity-money and financial operations, commerce, implementation of socioeconomic and scientific-and-technical projects. This is the definition for the following concept:
Business risk
Financial loss
Labour loss
Loss of property
Loss of time
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Inventory of human resources at pharmaceutical companies is based on keeping of work record books, employee’s files, personal data sheets T-2. What parameter CANNOT be estimated by the analysis of the above-mentioned date?
Average payroll strength
Labour market state
Data on the staff turnover
Staff categories
Average staffing number
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The equity capital of a pharmacy is 7500 UAH, the liabilities make 2500 UAH. According to the formula of balance calculation given in the Statement of Standard Accounting Practice 2 the amount of pharmacy assets will be as follows:
4 000 UAH
2 500 UAH
12 000 UAH
7 500 UAH
10 000 UAH
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Forensic toxicological analysis of a mineralizate revealed copper. For preliminary determination of copper ions the following substance is used:
Plumbum diethyldithiocarbamate
Diphenylcarbazide
Dithizone
Sodium diethyldithiocarbamate
Diphenylamine
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A patient got intoxicated with nitrites. Nitrites can be detected by means of the reaction of azo-dye formation with the following acid:
Phosphoric
Sulfuric
Hydrochloric
Sulfanilic
Salicylic
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Admixtures can get into the herbal raw material during harvesting, drying and primary processing. Mineral admixtures include:
Sand, earth, stones
Other organs of the same plant
Metal objects
Droppings of birds and rodents
Other similar plants
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Preparations made out of eleutherococcus roots and rhizomes are administered as a tonic and adaptogenic drug. If these preparations cannot be found in a pharmacy, they can be substituted by the analogous preparations made of the following raw material:
Polemonium roots
Rhizomes and roots of valerian
Ginseng roots
Acorus calamus roots
Elecampane roots
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When a certain drug reduces the effect of another drug, such phenomenon is called:
Tachyphylaxis
Habituation
Antagonism
Sensibilization
Potentiation
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The ability of drugs to accumulate in the patient’s body is called:
Cumulation
Allergy
Synergism
Antagonism
Habituation
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As main reagent in test for phosphates admixtures the Ukrainian State Pharmacopoeia recommends to use:
Thioacetamide
Hypophosphite
Acetylacetone
Sulfomolybdenum
Cupric tartrate
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A patient has been administered a spasmolytic from the group of muscarinic receptor antagonists as a part of the complex treatment for renal colic. Specify this drug:
Atropine
Neostigmine
Dithylinum
Galantamine
Benzohexonium
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A common method for quantitative determination of drugs from the group of alkali metal halogenides is:
Permanganatometry
Nitritometry
Alkalimetry
Argentometry
Chelatometry
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Treatment of poisonings with inorganic mercury compounds includes the use of the following antidote:
Naloxone
Tetacinum-calcium
Desferal
Unithiol
Dexamethasone
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A patient has been taking isosorbi-de for stenocardia prevention for quite a long time. Now he notes a significant decrease in the effect of the drug. What is this phenomenon called?
Physical dependence
Allergy
Tolerance
Potentiation
Cumulation
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Marketing manager at a pharmaceutical factory is planning its communication policy. Which component of the marketing communication systems has the highest value for one contact?
Personal sale
Periodical advertising
'Public relations'
Sales promotion
TV advertising
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A patient with myocardial infarction has been given an intravenous injection of a direct-acting anticoagulant. Select it among the listed drugs:
Neodicumarinum
Heparin
Calcium gluconate
Thrombin
Vikasolum
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Incoming control is conducted in the course of wholesale and retail trade, such control is carried out during receipt of goods by visual inspection or analysis of drug. Incoming control is carried out by authorized person, which is assigned by:
Head of regional structure
The order of head of territorial inspection
State inspection of drugs quality control
Managers order
Proprietor of an enterprise
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When a pharmacy records goods as received, it normally specifies the amount of the markup intended for expenditure coverage and profit gaining. Give the definition for the markup:
The difference between the sales price and the customs price
The difference between the sale price and purchase price of goods
The difference between the sales price and markup
The amount of goods sold
Rummage (goods remains) at the end of the month
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A pharmacy received a batch of goods from a supplier. What is the main financial document for posting the goods at the pharmacy?
Goods delivery note
Requisition
Receipts note
Aquittance
Cash order
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According to the basic regulations for supply of medical products, pharmacies should be supplied with medicaments with a remaining shelf life of no less than ... %, and bacterial preparations of no less than ...%:
80 %, 60%
40 %, 20%
50 %, 40%
60 %, 30%
60%, 40%
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A patient with chronic bronchitis gets glaucine hydrochloride at a pharmacy. The patient must be warned about the following typical side effect of this drug:
Allergic skin rash
Increased intraocular pressure
Irregular heartbeat
Arterial pressure drop
Excitation of the central nervous system
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Select the reductant required for the determination of arsenic impurity in drugs (method 2):
Potassium iodide solution
Sodium hydroxide solution
Hydrochloric acid solution
Sodium hypophosphite
Sodium sulfite solution
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The amount of temporary disability benefit for pharmacy employees depends on the time in employment: employees with 5 years of service record receive ...%, 5 to 8 years -... %, over 8 years -... %.
20 %, 40%, 50% of the average wage
10 %, 30%, 50% of the averagewage
40 %, 50%, 90% of the average wage
25 %, 45%, 65% of the average wage
60%, 80%, 100% of the average wage
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A pharmacy produces some injection solutions that have to be apyrogenic. Solution of the following substance can be depyrogenized by method of adsorption with activated carbon?
Papaverine hydrochloride
Platyphyllini hydrotartras
Scopolamine hydrobromide
Glucose
Atropine sulfate
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A pharmacy has to prepare a soft drug based on the gel made from inorganic substances. Which of these high-molecular compounds can be used for preparing such a base?
Bentonites
Cellulose ethers
Starch
Polyethylene oxides
Collagen
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A pharmaceutical enterprise produces ointments. What base is applied for production of sulfur ointment simple?
Lanolin
Emulsion
Polyethylene glycol
Base 'For ophthalmic ointments'
Vaseline
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One of the account forms of a pharmacy is the statement of balance (Form 1) which consists of the assets and liabilities. What are the elements of the assets of a pharmacy?
Own capital
-
Own and borrowed funds
Borrowed funds
Current and non-current assets
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Which drug with antagonistic effect can be used to stop bleeding caused by prolonged use of neodicumarinum?
Etamsylate
Fibrinogen
Vikasolum
Aminocapronic acid
Ascorbic acid
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A pharmacy received an order for 2500 ml of isotonic sodium chloride soluti- on. How much sodium chloride and water for injections should be taken to prepare this dosage form?
30,0 g of sodium chloride and 2500 ml of water for injections
50,0 g of sodium chloride and 2450 ml of water for injections
22,5 g of sodium chloride and 2500 ml of water for injections
25,0 g of sodium chloride and 2500 ml of water for injections
100,0 g of sodium chloride and 2400 ml of water for injections
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Powders that quickly enter into a reaction in presence of water and emit carbon dioxide relate to the following group:
Powders for external use
Nasal powders
Effervescent powder
Powders for oral use
Soluble powder
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A patient suffering from allergic rhinitis was prescribed ephedrine in form of nasal drops. The patient has significantly benefited from nasal instillation, and this stimulated him to use the drug every 2 hours. But under these conditions the drug appeared to be ineffective. What is the most likely cause of this phenomenon?
Cumulation
Tachyphylaxis
Idiosyncrasy
Allergy
Drug dependence
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Which anaesthetic, anti-inflammatory, the least harmful for the stomach preparation can be recommended to a patient with exacerbation of rheumatoid arthritis?
Indometacinum
Acetylsalicylic acid
Diclofenac sodium
Celecoxib
Ibuprofenum
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A teenager with hyporexia has been recommended to drink medicinal herbal tea of the following composition: Herba Absinthii, Herba Millefolii. Specify the characteristic microscopic features of Artemisia absinthium, which indicate its presence in the herb mixture:
T-shaped hairs along the leaf edge
Retor-shaped hairs
Simple and capitate hairs
Branched and capitate hairs
Branched, simple and ciliated hairs
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A laboratory received some herbal raw material for analysis. The plant had flowerheads up to 4 cm in diameter, the marginal flowers were agamic, blue, funnel-shaped; the inner flowers were bisexual, purple, tubular. What plant are these features typical for?
Centaurea cyanus
Polygonum persicaria
Scutellaria baicalensis
Solidago virgaurea
Viola tricolor
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Spesify the type of the following liniment: Ol. Helianthi 7,4 Sol. Ammonii caustici 25 ml Ac. Oleinici 0,1 M.f. linimentum D.S. To be rubbed in.
Liniment-solution
Combined liniment
Liniment, emulsion o/w
Liniment, emulsion w/o
Liniment-suspension
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During the combined pharmacotherapy a patient with peptic ulcer presented with blackcoloured feces. What drug might have caused such change?
Ranitidine
Bismuth subcitrate
Actovegin
Metronidazole
Omeprazole
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A female patient in the first trimester of pregnancy has been diagnosed with acute pyelonephritis. What is the antibiotic drug of choice for treating this patient?
Amoxicillin
Chloramphenicol
Gentamicin
Amikacin
Norfloxacin
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A man with a long history of chronic hepatitis has been diagnosed with pneumonia. Which of the following antibacterial drugs can be applied in this clinical situation?
Amoxicillin
Vancomycin
Tetracycline
Rifampicin
Biseptol
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A pharmaceutic plant producing aerosol forms uses liquefied gases as propellents. Which of the following substances relates to the group of liquefied gases?
Freons
Methylene chloride
Nitrous oxide
Ethylene chloride
Nitrogen
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A patient fell ill with severe pneumonia was prescribed ceftriaxonum once a day. Prescription of ceftriaxonum once a day connected with the fact that the drug:
Has bactericidal effect
Slowly eliminated from the body
Poorly absorbed from the injection site
Pluripotential
Accumulates in the lungs
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A patient with moderately severe pneumonia has been administered ceftriaxone 1 time per day. The drug should be taken once a day due to the following properties:
Slow excretion
Presence of bactericidal action
Cumulative ability
Poor absorption from the injection site
Wide range of action
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Which of the following is the drug of choice for bronchial asthma attacks prevention?
Ambroxol
Cromolyn sodium
Salbutamol
Diphenhydramine hydrochloride
Drotaverine
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A pharmaceutist is preparing an ointment under aseptic conditions on the sterile ointment base - composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technology of ointment preparation is typical for the following substance:
Pilocarpine hydrochloride
Sodium sulfate
Benzylpenicillin sodium salt
Thiamine chloride
Sodium chloride
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Oxidation of some toxins within the body results in generation of compounds that increase their toxicity. Thus, due to the oxidation of heptachlor in the body the folowing compound is formed:
Carbon dioxide
Carbon monoxide
Heptachlor epoxide
Heptachlor oxide
Hexachlorocyclohexane
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Company’s activity aimed at planning, organization and control of physical movement of materials and finished goods from the production site to the place of their utilization for the purpose of covering the consumer needs and gaining profit, is called:
Demand
Management
Advertising
Supply
Marketing
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A pharmaceutist made 10 powders containing atropine sulfate at a rate of 0,00005 pro dose. What trituration did he use?
1:20
1:1000
1:100
1:10
1:50
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In course of isoniazid identification a pharmacy analyst boiled thoroughly the substance with 2,4-dinitrochlorobenzene. The substance turned yellow, after adding alkaline solution it turned first violet and then brownish-red. As a result of this reaction the following aldehyde derivative is produced:
Glyoxylic
Hexanic
Glutamic
Gluconic
Glutaconic
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In order to verify identity of tropan derivatives, Vitali’s reaction is applied. For that purpose the medications should be first decomposed with nitric acid and then treated with alcoholic solution of potassium hydroxide and acetone. What effect will be observed?
The solution will turn purple
The solution will turn green
Setting of white precipitate
Emission of gas bubbles
Setting of black precipitate
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A pharmaceutical factory produces herbal juice out of fresh raw material. What operation should be performed at the stage of juice purification?
Adsorption
Crystallization
Heating followed by quick cooling
Filtration
Sedimentation
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Absorption of tetracycline preparations will be reduced when they are administered simultaneously with antacids. This is an example for:
Pharmacokinetic incompatibility
Drugs synergism
Functional drugs antagonism
Pharmacodynamic incompatibility
Pharmaceutical incompatibility
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A pharmacy got an order for manzanita decoction and hexamethylenetetramine. A pharmacist cancelled it with a stamp 'Invalid prescription'. What is the reason for the incompatibility?
Insolubility
Oxidization
Eutectic
Deposition
Moisture-repellant
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What substance will impede reaction of iodoform test aimed at detection of ethyl alcohol in the biological material?
Isoamyl alcohol
Phenol
Formaldehyde
Methanol
Acetone
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A 24-year-old patient has been suffering from diabetes mellitus type I for 8 years. Diabetic nephropathy provoked development of symptomatic arterial hypertension. Which of the folowing drugs is indicated for long-term therapy?
Dibazol
Clonidine
Dichlothiazide
Propranolol
Enalapril
‹ Назад
Далі ›
Analgin substance has been sent for analysis. What method allows to evaluate quantitative content of analgin?
Alkalimetry
Chelatometry
Acidimetry
Iodometry
Permanganatometry
‹ Назад
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A pharmaceutist prepares internal drops with the following formulation: 5 ml of adoniside, 10 ml of valerian and lily-of-the-valley tincture each, 0,1 g of menthol, 2,0 g of potassium bromide. It will be efficient to dissolve potassium bromide in the following substance:
In the lily-of-the-valley tincture
Potassium bromide should be added into the selling vial last of all
In the adoniside
In the mixture of tinctures
In the valerian tincture
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A pharmaceutist is preparing vaginal suppositories by method of pouring. Which hydrophilic base can he use for this purpose?
Vitepsol
Polyethylene oxide
Cocoa butter
Butyrol
Hard fat
‹ Назад
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Treatment course of essential hypertension includes diuretics. Which diuretic DOES NOT NEED to be combined with potassium preparations?
Triamteren
Ethacrynic acid
Clopamide
Furosemide
Dichlothiazide
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A pharmacy store was supplied with 100 packs of a product listed as Nitroglycerine. With regard to its physicochemical properties this preparation should be rated among the following drug group?
Highly inflammable substances
Explosive substances
Combustible substances
Volatile substances
Explosion hazardous substances
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During an operation a dentist needs to reduce salivation in a patient. The dentist has to use a drug of the following pharmacological group:
Muscarinic receptor blockers
Muscarinic cholinomimetics
Adrenoceptor blocker
Adrenomimetics
Muscarinic and nicotinic cholinomi-metics
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A patient with hypertensive crisis received an injection of ganglionic blocker benzohexonium. What side effect might be expected after the drug injection?
Taste violation
Central nervous system depression effect
Diarrhea
Orthostatic hypotension
Withdrawal (abstinence) syndrome
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Pharmaceutical chemistry studies methods of drug synthesis. Interaction of anesthesin with beta-diethylaminoethanol in presence of sodium alcoholate with following acidation with hydrochloric acid results in origination of:
Xycain
Trimecaine hydrochloride
Procaine hydrochloride
Procainamide hydrochloride
Tetracaine hydrochloride
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A pharmacy procured common origanum. What drying conditions should be applied for producing high quality crude drug?
80 - 90oC
35 - 40oC
60 - 70oC
50 - 60oC
70 - 80oC
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For accounting business transactions carried out in a pharmacy the synthetic accounts are used. Their list is given in the Chart of Accounts. Balances of the I, II and III account classes are used for completion of the following document:
Liabilities
Assets
First section of the liabilities balance sheet
Fourth section of the liabilities balance sheet
Profit and Loss Account
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An interhospital pharmacy got an order from a surgical department for a depolarizing muscle relaxant for surgical interventions. What drug was ordered?
Methacin
Nicotine
Hygronium
Dithylinum
Atropine sulfate
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Далі ›
A patient who has taken phenobarbi-tal for a long time was prescribed diclofenac sodium. However the anti-inflammatory effect of diclofenac appeared to be less than expected due to the pharmacokinetic interaction of these drugs. Such interaction might be the result of the following processes:
Reduced protein concentration in plasma
Increased drug dosage
Change of receptor sensibility
Decelerated drug metabolism in liver
Accelerated drug metabolism in liver
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Далі ›
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