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A pharmaceutist prepared powders including extract of belladonna in the amount of 0,015 per dose. For ten doses he had to take the following amount of dry extract:
0,03 g
0,15 g
0,3 g
0,015 g
1,5 g
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A pharmaceutical company focuses on selling a diverse range of products covering different customer groups and regions. What kind of organizational structure is typical for such company?
Decentralized
Divisional
Bureaucratic
Functional
Centralized
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A pharmaceutical company produces cordiamin solution. During the quality control its quantitative content was determined by means of refractometry. For this purpose an analytical chemist measured:
Angle of rotation
Index of refraction
Density
Intensity of absorption
Viscosity
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Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?
Acetylsalicylic acid
Streptokinase
Heparin
Ticlopidine
Phenylinum
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On the 4th day of treatment with indomethacin a 55-year-old patient developed gastric bleeding as a result of ulceration of the gastric mucosa. Ulcerogenic effect of this drug is due to a decrease in activity of the following enzyme:
Cyclooxygenase-1 (COX-1)
Prostacyclin synthetase
Lipoxygenase (LOX)
Thromboxane synthetase
Cyclooxygenase-2 (COX-2)
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A patient complaining of dry mouth, photophobia and blurred vision has been delivered to the admission ward. Objectively: the skin is hyperaemic, dry; mydriatic pupils and tachycardia are present. He has been diagnosed with belladonna alkaloids intoxication. Which of the drugs should be given as an antidote?
Arminum
Dipiroximum
Neostigmine
Aceclidine
Pylocarpine
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To stop the delusions and hallucinations in a schizophrenic patient a doctor administered aminazine. What is the mechanism of antihypoxic action of this drug?
Inhibition of adrenergic processes in the CNS
Inhibition of cholinergic processes in the CNS
Stimulation of cholinergic processes in the CNS
Stimulation of adrenergic and dopaminergic processes in the CNS
Inhibition of dopaminergic processes in the CNS
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During a surgical operation the muscle relaxant tubocurarine chloride was used. What antagonist drug should be injected in order to allow the patient to breathe independently?
Aethimizolum
Веnzohexonium
Cytitonum
Dithylinum
Neostigmine
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A patient came to a drugstore and ordered cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?
Herba Achilleae millefolii
Rizoma et radix Sanquisorbae officinalis
Rizoma Calami
Folium Uvae ursi
Radix Taraxaci officinalis
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A pharmaceutist has prepared a tincture of althaea root. What is the proportion of herbal raw material and extractant?
1:100
1:20
1:10
1:400
1:30
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An analytical chemist working at a pharmacy identifies oxacillin sodium salt. As a reagent he uses hydroxylami-ne hydrochloride solution in presence of sodium hydroxide solution and copper nitrate solution. What structural fragment of a drug molecule can be detected by means of these reagents?
Thiadiazole cycle
Furan cycle
Beta-lactam cycle
Thiazolidine cycle
Isoxazole cycle
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Diethyl ether relates to simple ethers. Prior to its identification by using the boiling temperature an analytical chemist must ensure that there are no:
Peroxides
Alcohols
Non-volatile residue
Reducing substances
Carboxylic acids
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In order to detect peroxides in the anesthetic ether an analytical chemist should use the following reagent:
Sodium hydroxide
Potassium iodide
Sodium thiosulfate
Potassium permanganate
Potassium chloride
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A syrup contains 82 parts of sugar syrup; 1 part of KJ (KBr); 12 parts of liquid thyme extract and 5 parts of 96% ethanol. What is this medicine called?
Broncholytin
Licorice syrup
Cholosasum
Ambroxol
Pertussinum
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A pharmaceutical enterprise that has achieved high sales rates and customers’ recognition will reach the highest profit at the following stage of the product life cycle:
Decrease
Maturity
Growth
Development
Market penetration
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A pharmaceutic plant producing ointments can use the following equipment at the packing stage:
Rezepin automatic machine
Disc machines
Screw and piston dosing machines
Rotary machines
Eccentric machines
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Aerosol workshop of a pharmaceutic plant uses propellents of different groups. What propellents relate to the group of compressed gases?
Nitrogen, nitrous oxide, carbon dioxide
Vinyl and methyl chloride
Freons
Propane, butane, isobutane
Methylene chloride, ethylene chloride
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An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?
Nitritometric determination
Mercurimetric determination
Chelatometry
Iodometry
Bromatometry
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Which preparation is the specific antidote in case of intoxication with iron preparations?
Bemegridum
Penicillamine
Atropinum
Deferoxamium
Protamine sulfate
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A pharmaceutist prepared solution of ethacrydine lactate. What is the peculiarity of this substance dissolving?
Grinding in a mortar with water
Dissolving in potassium iodide solution
Dissolving in hot water
Dissolving in freshly distilled water
Dissolving in cold water
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A pharmacy produces compounded drugs. What kinds of internal control of drugs production are required?
Written, qualitative and quantitative analysis
Written, physics and chemical
Written, interrogatory, sell control
Written, organoleptic, sell control
Written and sell control
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A pharmacy analyst can verify presence of iron cation (II) in a drug formulation by means of the following solution:
Ammonium sulfide
Sodium phosphate
Potassium bromide
Magnesium sulfate
Sodium chloride
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A pregnant woman fell ill with severe pneumonia. Which of these antimicrobials should be administered to this patient?
Cefotaxime
Tetracycline hydrochloride
Gentamicin sulfate
Biseptol
Ofloxacin
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A pharmacy manager is working out a schedule for a pharmaceutist who is responsible for prescription reception and drug serving out. What is the weekly working time for one employee?
38 hours
30 hours
Irregular working week
36 hours
40 hours
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A pharmaceutist was on a business trip. What is the deadline for submitting a travel expense report?
A week after returning from a trip
There is no deadline
Three working days after returning from a trip
Ten working days after returning from a trip
Four working days after returning from a trip
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An advance holder (accountant) was given some money from the cash fund of an enterprise for purchase of office accessories. After the cash advance the advance holder must submit the complete application of funds statement no later than:
One week
Five working days
Such term isn’t established
Ten working days
Third banking day
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A pharmacy selling officinal drugs is a successful participant of the pharmaceutical market. Specify the business transaction which is qualified as pharmacy revenue:
Receipt of advance payment made by a customer
Salary accounting
Tax charge
Writing-off of the cost of goods sold
Proceeds of a structural subdivision of a pharmacy
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A pharmacy provides its customers with officinal medicines. Specify the business transaction which is qualified as pharmacy expenses:
Pharmacy proceeds
Proceeds of a structural subdivision
Posting of goods
Write-off of cost of goods sold
Personal income tax
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Medicinal plant Rhamnus cathartica is used as a laxative. What part of this plant is used as herbal raw material?
Shoots
Leaves
Roots
Fruits
Rind
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When the glucose is heated with the copper-tartrate reagent (Fehling’s reagent) the brick-red precipitate settles down. It indicates presence of the following group:
Ketonic
Aldehyde
Carboxyl
Amide
Etherific
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For the purpose of sales stimulation a pharmaceutical wholesale company grants its customers a discount according to the social contract and on condition of their loyalty. Specify the type of discount:
Dealer
Seasonal
Discounts for quantity of purchased goods
-
Bonus
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Before accepting the goods by a pharmacy, they should be checked for quantity and quality. If there is no discrepancy, the pharmacy issues a warrant for receipt of goods. This warrant is valid for:
1 year
20 days
15 days
3 months
10 days
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A patient got intoxicated with an unknown substance. Test of biological material revealed pH=2,0-3,0. The chemico-toxicological analysis should be carried out for the following group of substances:
Ammonia
Alkali metal salts
Weak organic acids and heavy metal salts
Mineral acids or large amounts of organic acids
Alkalis
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One of the quality indicators for finished ampoules is lack of residual stress in the glass. Which operation at the stage 'Preparation of ampoules to be fi-lled'eliminates this imperfection?
Ampoule drying
Capillary opening
Ampoule annealing
Ampoule sterilization
Ampoule washing
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Companies producing injectable dosage forms apply different methods of ampoule sealing. Sealing against a jet of inert gases (nitrogen, argon, carbon dioxide) is suitable for the following injection solutions:
Easily oxidable
Photosensitive
Hydrolytically unstable
Thermostable
Viscous
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Quality control of tablets produced at a pharmaceutical enterprise involves quantitative determination of such subsidiary substances as talc and aerosil. What method is applied for such determination?
Titrimetric
Photocolorimetric
Gravimetric
Spectrophotometric
Chromatographic
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A 6-year-old child with pneumonia has been administered an antibiotic. After treatment the child lost his hearing. What group of antibiotics might have caused this complication?
Semi-synthetic penicillins
Aminoglycosides
Cephalosporins
Natural penicillins
Macrolides
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A 52-year-old patient had myocardial infarction and was discharged from the hospital after the stationery treatment. What daily dose of acetylsalicylic acid should be administered in order to prevent thrombosis?
1000 mg
100 mg
500 mg
50 mg
200 mg
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A woman died from pesticide poisoning as a result of processing of agricultural crops. Measurement of organophosphorous compounds in the extracts of biological material should be started with the following test:
Biochemical assay
Test for the presence of chlorine atom
Test for methoxy or ethoxy groups
Test for the phosphate ion
Test for the presence of a sulfur atom
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In the medical practice this compound is used as a disinfectant. In case of intoxication with this compound the patient’s urine turns olive or olive-black. Specify the compound:
Isoamyl alcohol
Ethyl ether
Phenol
Ethyl benzoate
Iodoform
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In order to identify a drug an analytical chemist of the State Inspectorate for Quality Control of Medicines carries out the reaction with ninhydrin solution. Specify the drug to be identified:
Streptocide
Cortisone acetate
Paracetamol
Methionine
Ascorbic acid
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A pharmaceutist prepared suppository mass with novocaine and cocoa butter, but it turned out to be crumbling. What substance to be added to form a plastic mass:
Paraffin
Vaseline
Wax
Anhydrous lanolin
Hydrous lanolin
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A pharmaceutist has to sterilize 400 ml of calcium gluconate solution for injections. Specify the time of autoclave sterilization of the solution at 120°C:
12 minutes
15 minutes
10 minutes
20 minutes
30 minutes
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Anesthesin relates to substances with local anesthetic activity and is a derivative of the following acid:
Para-aminosalicylic
Para-aminobenzoic
Para-aminophthalic
Para-aminobenzolsulfonic
Para-chlorbenzoic
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According to the State Pharmacopoeia of Ukraine, in order to test a substance for the highest level of magnesium impurities an analytical chemist must use the following solution:
Hydroxyquinoline
Resorcin
Benzaldehyde
Formaldehyde
Pyridine
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Select a reagent that should be applied by an analytical chemist in order to detect alkaloids in the herbal raw material:
Bromine water
Dragendorff reagent
Trim-Hill reagent
Stahl’s reagent
Alkaline solution
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Preparations of sorrel roots can have both a laxative and astringent effect. This is due to the presence of the following biologically active substances:
Flavonoids and essential oils
Iridoids and vitamins
Coumarins and phenol glycosides
Essential and fatty oils
Anthracene derivatives and tannins
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Emodin, an anthracene derivative, haspurgative effect. Large quantities of anthracene-derived groups of emodin are contained in the fruits of the following plant:
Blueberry (Vaccinium myrtillus)
Elder (Sambucus)
Blackcurrant
Buckthorn
Alder buckthorn (Frangula alnus)
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A pharmacy manager is writing the monthly 'Inventory report'. What business transactions should be represented in the expenditure item of the report?
Amortization charged to operation
Payroll payment
Extra-evaluation of laboratorypackaging works
Herbal raw material purchases
Drug sales
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A pharmacy has a license for selling narcotic drugs. The warrant for the receipt of these drugs from the pharmacy warehouse is valid for:
No longer than 1 calendar days from the date of issue
No longer than 3 months from the date of issue
No longer than 1 year from the date of issue
No longer than 10 calendar days from the date of issue
No longer than 5 calendar days from the date of issue
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Which of the pharmacy departments is responsible for checking the quantity and quality of received goods, their storage and dispensing to other departments?
Department of over-the-counter drugs
Inventory department
Department of finished dosage forms
Compounding and production department
Department of curative cosmetics
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The possible admixture in the crop of raw coltsfoot leaves (Tussilago farfara) is the leaf of:
Cotton burdock (Arctium tomentosum)
Marshmallow (Althaea officinalis)
Nettle
Primula officinalis
Common plantain
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In order to determine the purity a drop of lavender essential oil was applied on a strip of filter paper and warmed up in the stream of warm air. Some time later the stain increased in diameter. What impuri- ty substance was found in the lavender oil?
Ethanol
Diethyl ether
Fatty or mineral oil
Phenol
Acetone
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A pharmacy received a batch of raw material - chamomile flowers. How should this material be stored?
According to the list A requirements
As a narcotic raw material
According to the list B requirements
Separately from all other kinds of raw material
In a light room
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A patient acquired mint leaves at a pharmacy. What recommendations regarding infusion of this herbal raw material must be given by the pharmaceutist?
The infusion is to be prepared at room temperature
The extract is to be artificially cooled 15 minutes after infusing
The infusion is to be prepared on an open fire
The infusion is to be prepared in a tightly closed vessel
The extract is to be immediately filtered after infusing
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A patient has been administered a solution containing boric acid and camphor. What solvent should his doctor prescribe in order to prevent physical incompatibility?
Ethyl alcohol 70%
Purified water
Glycerol
Sunflower oil
Ethyl alcohol 40%
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A patient has chronic pancreatitis with apparent presentations of pancreatic exocrine hypofunction. Which of the following drugs would be the most appropriate in this case?
Оmерrаzоlе
Acidin pepsinum
Раncreatinum
Dе-Nоl
Drotaverine
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A patient got an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient has presented with red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucous membrane. What is the cause of this complication?
Abstinence syndrome
Tachyphylaxis
Immediate allergy
Local irritation
Delayed allergy
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A 15-year-old patient has been first diagnosed with type I diabetes mellitus. Which antihyperglycemic drug should be administered in this case?
Glibenclamide
Diabetone
Insulin
Glurenorm
Metformin
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A patient with gastric ulcer has been administered omeprazole. What is its mechanism of action?
Inhibition of H+K+-ATPase
Stimulation of mucus production
Blockade of M-cholinergic receptors
Blockade of histamine H2 receptors
HCl neutralization
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A manufacturing company initiates changes to the package insert of a drug aimed at limitation of its use. What type of marketing is used by the company in this case?
Conversion
Stimulating
Synchromarketing
Remarketing
Counteractive
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When developing a new drug a manufacturer may apply different strategies of brand use. If a company uses one brand name for all of its products, such strategy is called:
Brands for individual drugs
The combination of brand name with an individual drug brand
Multi-brand approach
Group brands
Individual brands
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A doctor prescribed his patient an emulsion of olive oil which includes anesthesin. To incorporate anesthesin into the emulsion it must be dissolved:
In the purified water
In the alcohol, and then added to the primary emulsion
In the primary emulsion
In oil before preparing the emulsion
In the finished emulsion
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The patient has been prescribed Lini-mentum Rosentali. It is composed of:
Castor oil, calcium chloride, alcohol
Iodine, potassium chloride, glycerin
Chloroform, methyl salicylate, turpentine
Sunflower oil, ammonia, oleic acid
Paraffin, alcohol, chloroform, iodine
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Injection solutions of salts derived from weak acids and strong bases require stabilization. What stabilizers are used for these solutions?
Ascorbic acid
Trilon B
0,1 M sodium hydroxide solution
0,1 M acid chloride solution
Buthylhydroxytoluene
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A pharmaceutical plant produces suppositories. What is the best method for their manufacturing in industrial quantities?
Lyophilization
Pressing
Outpouring
Stamping
Pumping-out
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О-methylation is an important way of biotransformation of organic substances in the body. Compounds subject to О-methylation should contain:
Nitro groups
Carboxyl groups
Thiol groups
Amino groups
Phenol groups
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A pharmaceutist prepares a suspension ointment. What substance is soluble in water, but should be incorporated into the dermatological ointments as a suspension?
Zinc oxide
Sulfacyl sodium
Furacilin
Resorcinol
Potassium iodide
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It is necessary to analyze herbal raw material in form of black glossy drupes 6-8 mm in diameter, with a large, firm, globular, light brown kernel containing one seed. The drupes have sweet and slightly astringent taste. This herbal raw material should be identified as fruits of:
Bird cherry
Black chokeberry
Buckthorn
Hawthorn
Blueberry
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Method of gas-liquid chromatography is often applied for identification and quantitative determination of toxicologically meaningful substances. Substances can be placed into the chromatograph dispenser in the following aggregate states:
Liquid
Gaseous
Gaseous and solid
Liquid and gaseous
Liquid and solid
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Which of the following non-steroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?
Nimesulide
Diclofenac
Acetylsalicylic acid
Piroxicam
Indomethacin
‹ Назад
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Which drug is used for thrombolysis in case of acute myocardial infarction?
Acetylsalicylic acid
Pentoxifylline
Alteplase
Fraxiparine
Heparin
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When doing calculations to determine the limit of the cash balance, an accountant must specify the actual amount of cash receipts. What time period should be taken into account?
1 year prior to calculation
7 days prior to calculation
Three months prior to calculation
10 days prior to calculation
Six months prior to calculation
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A doctor gave a prescription for the tincture of digitalis with hydrochloric acid. What is the reason for their incompatibility?
Gassing
Change in odour
Change in colour
Precipitation
Hydrolysis (with no visible changes)
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At the initial stage of establishing a pharmaceutical enterprise the internal disciplinary regulations should be adopted. One of the primary matters is the duration of the lunch break for the employees. According to the Labour Code of Ukraine, the break duration must be as follows:
Up to 2 hours
Not less than 3 hours
-
Up to 1 hour
2,5 hours
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A woman asked a pharmaceutist to dispense an antipyretic for an 8-month-old child. Which drug should be recommended?
Indomethacin
Diclofenac sodium
Acetylsalicylic acid
Piroxicam
Paracetamol
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A 70-year-old patient consulted a doctor about elevated arterial pressure. He has a history of benign hyperplasia of prostate. What drug should be administered in this case?
Doxazosin
Diltiazem
Propranolol
Losartan
Ем^ні
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Having ascertained that the quality of raw material meets the requirements of the analytical normative documentation the quality control department should issue a document. Specify this document:
Standard
Certificate of analysis
Order
Request
Pharmacopoeia entry
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A pharmaceutist revealed incompatibility in a prescription for powders with ascorbic acid and hexamethylene tetrami-ne. What process takes place when these components are combined?
Mixture dampening
Adsorption
Immiscibility
Eutectic
Isolation of crystallization water
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Efficiency of aerosol therapy is to a considerable extent determined by the size of disperse particles. What factor determines the size of aerosol particles during dispersion of an aerosol?
Reduction range, container quantity
Percentage of phase, filling temperature
System homogeneity, dispersion velocity
Exit port diameter, propellent vapour pressure
Fractional composition, containers filling method
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Prior hydrolysis is necessary in case of quantitative determination of the following drug by the nitritometric titration:
Paracetamol
Anesthesin
Sodium p-aminosalicylate
Procaine hydrochloride
Dicaine
‹ Назад
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A pharmacy plans to purchase and retail goods of different stock record units. Which group of goods does VAT reduction apply to?
Curative cosmetics
Baby food
Optics
Perfumes
Medicaments
‹ Назад
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An analytical chemist determines the admixture of sulphates in the boric acid. What is the main reagent to be added?
Silver nitrate
Barium chloride
Ammonium oxalate
Sodium sulphide
Potassium ferrocyanide
‹ Назад
Далі ›
Recommend a patient with acute bronchitis a mucolytic drug that facilitates expectoration:
Drotaverine hydrochloride
Diclofenac sodium
Loratadine
Glaucine
Acetylcysteine
‹ Назад
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A patient with atopic dermatitis presented at the hospital. Which drug with anti-inflammatory and antiallergic effect should be administered to this patient?
Aethamidum
Retabolil
Oxytocin
Prednisolone
Insulin
‹ Назад
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A patient with atherosclerosis has been administered an anti-atherosclerotic agent. Specify this drug:
Phenylbutazone
Ascorbic acid
Phenofibrate
Dexamethasone
Pyracetam
‹ Назад
Далі ›
A patient after bee’s stings has angi-oedema (Quincke’s edema). Which drug should be immediately inject to eliminate this condition?
Platyphyllini hydrotartras
Epinephrine hydrochloride
Anaprilinum
Sodium chloride
Atropine sulfate
‹ Назад
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A pharmacy received a batch of medicines from a pharmacy depot. Specify the drug subject to the controlled substance inventory in pharmacies:
Analgin
Acetylsalicylic acid
Paracetamol
Novocaine
Dicaine
‹ Назад
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A pharmaceutical company conducted an age-specific segment analysis of the regional antihistamine market. It revealed the lack of antihistamines for children. The company will consider this segment as:
Unattractive segment
Market door
Market niche
Segment requiring further research
Market share
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The manufacturing pharmaceutical company 'Elema'set up its own corporate pharmacy. In this case, it uses the following distribution channel:
Zero level
Second level
Fourth level
First level
Third level
‹ Назад
Далі ›
A pharmacy received some medicines from the warehouse. What medicine is subject to the stocktaking in the pharmaceutical institutions?
Codeine
Butadionum
Aminalonum
Analginum
Corvalolum
‹ Назад
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A pharmacy sells drugs by retail. Omnopon relates to the following group of controlled drugs:
Potent
General sale list
Psychtropic
Narcotic
Toxic
‹ Назад
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A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:
Ursodeoxycholic acid
Citric acid
Acetylsalicylic acid
Gamma-aminobutyric acid
Mefenamic acid
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A patient with acute heart failure and intolerance of cardiac glycosides has been given an injection of dobutamine. What is the mechanism of its action?
Stimulation of α- adrenoceptors
Inhibition of phosphodiesterase
Stimulation of M-cholinergic receptors
Blockade of K+-, Na+-ATPase
Stimulation of β₁-adrenoceptors
‹ Назад
Далі ›
One of the methods of quantitative analysis of active substances in the raw material is the biological standardization. It can be applied with the following group of biologically active substances:
Tannins
Cardiac gliycosides
Mucilages
Fatty oils
Alkaloids
‹ Назад
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In the process of pressing the tablets adhere to the pressing tool. The technological error is the lack of:
Dyes
Lubricants
Diluents
Adhesive substances
Disintegrants
‹ Назад
Далі ›
An elderly patient has constipation caused by hypotonia of colon. What drug should be administered to this patient?
Sodium sulfate
Novocaine amide
Atropine sulfate
Castor oil
Bisacodyl
‹ Назад
Далі ›
A forensic medicine laboratory received some biological material. It should be analyzed for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:
Chloroform
Propanol acidified with oxalic acid
Water alkalized with ammonia solution
Water acidified with sulfuric acid
Ethanol acidified with oxalic acid
‹ Назад
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A chemical department produces alcohol solution of boric acid. What filters are used for filtration of this solution?
Nutsch filter
Membrane filter
Pressure filters
Paper filter
Bag filter
‹ Назад
Далі ›
A pharmacy received a prescription for preparation of dermatological ointment with benzylpenicillin. Specify the type of ointment that necessary to prepare:
Liquid ointment
Suspension ointment
Hydrophilic ointment
Combined
Alloy ointment
‹ Назад
Далі ›
A pharmacy received a prescription for powders with doctor’s instruction to dispense powders in gelatin capsules. Which of the following substances is included in the composition of these powders?
Magnesium oxide
Diphenhydramine
Glucose
Streptocide
Ethacridine lactate
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Далі ›
In course of pharmacotherapy of bronchitis a patient was found to have dyspeptic disorders, photodermatitis, liver dysfunction. Which of the prescribed drugs might have caused these manifestations?
Codeine phosphate
Ascorbic acid
Acetylcysteinum
Paracetamolum
Doxycyclin
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From the pharmaceutical stock select an anticholinesterase drug to be administered to the patients with atony of the intestine and urinary bladder in the postoperative period:
Proserin
Benzohexonium
Dithylinum
Atropine sulfate
Phosphacolum
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Most alkaloids are isolated from the biological material by means of polar solvents. Which of the listed alkaloids is isolated by the way of distillation with water vapour?
Cocaine
Coniine
Atropine
Quinine
Strychnine
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Comparative analysis of the performance of two pharmacies showed that the trade stock in terms of days was 20 and 30 days respectively. Which of these indicators is NOT USED for calculating the trade stock?
Turnover
The rate of trade mark-up
Wage fund
Sales volume
The left-over goods in terms of settlement prices
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A pharmacy received a batch of drugs from a wholesale firm. What document signed by an authorized person is the basis for further sale of drugs?
Opinion letter of the territorial inspectorate
Quality certificates
National register of medicinal products
Register of medicinal products accepted for sale
Information on state registration
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A patient who has been suffering from gastric diseases for a long time is found to have hyperchromic anemia. Which of the following drugs is applied for this pathology treatment?
Ascorbic acid
Ferrum Lek
Cyanocobalamine
Unitiol
Охуferriscorbone
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A phytopreparation 'Flacarbi-num'has spasmolytic, anti-inflammatory and antiulcer effect. This preparation is produced out of the following plant:
Pot marigold (Calendula officinalis)
Mountain angelica (Aralia mandshuri-ca)
Licorice (Glycyrrhiza)
Jacob’s ladder blue (Polemonium caeruleum)
Buckeye (Aesculus)
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Specify the reaction to the ester-type drugs that is tolerated by the State Pharmacopoeia of Ukraine:
Formation of iron hydroxamates
Formation of 3-bromphenol
-
Formation of indophenol
Formation of azo dye
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Streptocide, sulfacyl sodium, norsulfazole or sulfadimezinum can be identified by means of the reaction to form:
Azo dye
-
Murexide
Fluorescein
Iodoform
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Which of the following drugs can be quantified by an analytical chemist by ceriometry method?
Vicasolum
Phenobarbital
Phenyl salycylate
Sodium benzoate
Acetylsalicylic acid
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Three founders set up a business entity for the wholesale distribution of medicines and healthcare products. Specify the form of such company:
Corporate
Individual
Unitary
Utility
Public
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Pharmaceutical market is in such a situation when there is only one company selling a certain product. Specify the competitive structure of the market:
Pure monopoly market
Monopolistic competitive market
Oligopolistic market
Pure competition market
Pure monopoly market and oligopolistic market
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The founders are going to open a retail pharmacy. What way of business running is stipulated in this case?
Limited
Without preliminary licencing or registration
Normative
Licence-based
Free
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A pharmaceutist prepared 150 ml of Adonis vernalis infusion using dry extract concentrate [1:1] that had to be weighed in the amount of :
15, 0
5,0
22, 5
10, 0
7, 5
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A pharmacy received a prescription: Rp.: Dibazoli0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose :
0,27
2, 7
0, 25
0, 30
0, 26
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An analytical chemist determines the quantity of a drug by the method of indirect bromatometry. Which of the following titrated solutions is to be used?
Sodium nitrite
Sodium thiosulfate
Sodium edetate
Calcium bromate
Silver nitrate
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In order to identify a drug an analytical chemist of the State Inspectorate for Quality Control performs a lignin test. Specify this drug:
Cortisone acetate
Methionine
Streptocid
Analgin
Ascorbic acid
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The main active components of hawthorn berries are flavonoids. What is their pharmacological effect?
Antispasmodic and anti-inflammatory
Diuretic and styptic
Tonic and antispasmodic
Hypotensive and sedative
Laxative and sedative
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An analytical chemist working at an analytical laboratory identifies a drug by the sulfite ions according to the requirements of the State Pharmacopoeia of Ukraine. What reagent gets decolorized during this assay?
Potassium nitrate solution
Iron (III) chloride solution
Potassium iodide solution
Ammonia solution
Iodine solution
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An analytical laboratory received 'Aether anaestheticus' for analysis. What reagent should be used for detecting acetone and aldehyde impurities according to the State Pharmacopoeia of Ukraine?
Sodium hydrosulfite solution
Alkaline solution of potassium tetrai-odomercurate
Hydroxylamine solution
Ammonium solution of argentum nitrate
Aqueous solution of potassium iodide
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Compulsory deductions from employee’s salary are made by the accounting department independently. Specify a deduction which can be made only on the grounds of written permit of an employee:
Contributions to the Social insurance fund for unemployment
Superannuation contributions
Contributions to the Social insurance fund for temporary disability
Alimony
Charitable contributions
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Natural persons registered as small business entities with simplified taxation scheme (2 group) have the limit for the annual amount of sales proceeds. Specify the proceeds limit:
3 million UAH
100 thousand UAH
750 thousand UAH
1 million UAH
5 million UAH
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Fatty oil containing unsaturated fatty acids is used for the prevention of atherosclerosis. Specify the herbal raw material used for oil production:
Hawthorn berries
Seeds of fennelflower
Seeds of flax
Fruits of dill
Fruits of black chokeberry
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The ampoule workshop produces solutions for injections. The aminophylli-ne solution for injections relates to the following group of solutions:
Solutions of salts composed of strong bases and weak acids
Solutions of substances requiring special purification
Solutions of salts composed of weak bases and strong acids
Solutions are not subject to heat sterilization
Solutions of easily oxidizable substances
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Phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different raw materials. Specify the biogenic stimulators of animal origin:
Liquid aloe extract, aloe liniment, aloe juice, biossedum
Vitreous body, placental suspension for injections, plasmolum, solcoseryl
Peloidinum, humisolum, torfotum, Fibs pro injectionibus
Peloidinum, humisolum, torfotum, plasmolum, solcoseryl
Liquid aloe extract, aloe liniment, plasmolum
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The planning of marketing strategy involves two successive stages. What are the stages of the strategic planning process?
Defining the mission and goals of a pharmaceutical company
Budgeting
Developing a program of activities
Making the list of tasks and problems
Describing the current marketing situation
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Benzathine benzylpenicillin is the drug of choice for treating the following disease:
Intestinal infection
Syphilis
Furunculosis
Pneumonia
Angina
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In order to identify ouabain (strophanthine G), a drug from the group of cardiac glycosides, an analytical chemist must prove the presence of a steroid cycle. What acid should be used as a reagent?
Citric
Chromotropic
Formic
Oxalic
Sulfuric
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An analytical laboratory has to analyze ferrous sulfate heptahydrate according to the State Pharmacopoeia of Ukraine. A test portion of the substance should be titrated with the following solution:
Ammonium cerium sulfate
Ammonium thiocyanate
Potassium bromate
Silver nitrate
Sodium edetate
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Urine of an intoxicated person was found to contain ecgonine. This indicates poisoning with the following substance:
Heroin
Phenacetin
Cocaine
Phenol
Caffeine
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A patient with schizophrenia has been administered a neuroleptic. Which of the listed drugs falls into this group?
Propranolol
Celecoxib
Morphine
Pyracetam
Aminazine
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A laboratory received some herbal raw material for analysis. It is a composition of ovoidpointed leaves up to 25 cm long and 20 cm wide; the leaf base is cuneate, the leaf edge is emarginate, The cutting is long and cylindric. The leaf venation is pinnatisect; the midrib and the first-order veins project significantly on the inferior surface of the leaf. The superior leaf surface is dark green, the inferior surface is light green. The plant has a weak narcotic smell. The taste cannot be determined. The plant is poisonous! The described herbal raw material relates to the following plant:
Passiflora incarnata
Vinca minor
-
Chelidonium majus
Datura stramonium
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A pharmaceutist has prepared an emulsion. Specify the way of incorporation of the fat-soluble substances:
They are incorporated in undissolved form
They are dissolved in oil
They are dissolved in purified water
They are added to the emulsifier
They are added to the finished emulsion
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A pharmacy received a prescription for a mixture. What drug substances are incompatible?
Phenobarbital + glucose
Sodium bromide + sodium chloride
Codeine phosphate + extract of Thermopsis
Papaverine hydrochloride + ami-nophylline
Novocaine + diphenhydramine
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The risk can arise from some forms of activity connected with production of goods and services, their selling, commodity-money and financial operations, commerce, implementation of socioeconomic and scientific-and-technical projects. This is the definition for the following concept:
Labour loss
Loss of property
Loss of time
Financial loss
Business risk
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Inventory of human resources at pharmaceutical companies is based on keeping of work record books, employee’s files, personal data sheets T-2. What parameter CANNOT be estimated by the analysis of the above-mentioned date?
Staff categories
Average payroll strength
Labour market state
Average staffing number
Data on the staff turnover
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The equity capital of a pharmacy is 7500 UAH, the liabilities make 2500 UAH. According to the formula of balance calculation given in the Statement of Standard Accounting Practice 2 the amount of pharmacy assets will be as follows:
2 500 UAH
10 000 UAH
4 000 UAH
12 000 UAH
7 500 UAH
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Forensic toxicological analysis of a mineralizate revealed copper. For preliminary determination of copper ions the following substance is used:
Dithizone
Plumbum diethyldithiocarbamate
Diphenylamine
Sodium diethyldithiocarbamate
Diphenylcarbazide
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A patient got intoxicated with nitrites. Nitrites can be detected by means of the reaction of azo-dye formation with the following acid:
Hydrochloric
Phosphoric
Sulfanilic
Sulfuric
Salicylic
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Admixtures can get into the herbal raw material during harvesting, drying and primary processing. Mineral admixtures include:
Other organs of the same plant
Other similar plants
Metal objects
Sand, earth, stones
Droppings of birds and rodents
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Preparations made out of eleutherococcus roots and rhizomes are administered as a tonic and adaptogenic drug. If these preparations cannot be found in a pharmacy, they can be substituted by the analogous preparations made of the following raw material:
Ginseng roots
Acorus calamus roots
Polemonium roots
Rhizomes and roots of valerian
Elecampane roots
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When a certain drug reduces the effect of another drug, such phenomenon is called:
Tachyphylaxis
Sensibilization
Habituation
Antagonism
Potentiation
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The ability of drugs to accumulate in the patient’s body is called:
Habituation
Antagonism
Cumulation
Synergism
Allergy
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As main reagent in test for phosphates admixtures the Ukrainian State Pharmacopoeia recommends to use:
Sulfomolybdenum
Acetylacetone
Thioacetamide
Cupric tartrate
Hypophosphite
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A patient has been administered a spasmolytic from the group of muscarinic receptor antagonists as a part of the complex treatment for renal colic. Specify this drug:
Dithylinum
Neostigmine
Galantamine
Benzohexonium
Atropine
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A common method for quantitative determination of drugs from the group of alkali metal halogenides is:
Nitritometry
Argentometry
Permanganatometry
Chelatometry
Alkalimetry
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Treatment of poisonings with inorganic mercury compounds includes the use of the following antidote:
Tetacinum-calcium
Unithiol
Naloxone
Dexamethasone
Desferal
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A patient has been taking isosorbi-de for stenocardia prevention for quite a long time. Now he notes a significant decrease in the effect of the drug. What is this phenomenon called?
Physical dependence
Potentiation
Allergy
Tolerance
Cumulation
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Marketing manager at a pharmaceutical factory is planning its communication policy. Which component of the marketing communication systems has the highest value for one contact?
Periodical advertising
'Public relations'
TV advertising
Personal sale
Sales promotion
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A patient with myocardial infarction has been given an intravenous injection of a direct-acting anticoagulant. Select it among the listed drugs:
Neodicumarinum
Calcium gluconate
Thrombin
Vikasolum
Heparin
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Incoming control is conducted in the course of wholesale and retail trade, such control is carried out during receipt of goods by visual inspection or analysis of drug. Incoming control is carried out by authorized person, which is assigned by:
Managers order
State inspection of drugs quality control
Head of regional structure
Proprietor of an enterprise
The order of head of territorial inspection
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When a pharmacy records goods as received, it normally specifies the amount of the markup intended for expenditure coverage and profit gaining. Give the definition for the markup:
The difference between the sales price and markup
The difference between the sales price and the customs price
The amount of goods sold
Rummage (goods remains) at the end of the month
The difference between the sale price and purchase price of goods
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A pharmacy received a batch of goods from a supplier. What is the main financial document for posting the goods at the pharmacy?
Goods delivery note
Requisition
Aquittance
Cash order
Receipts note
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According to the basic regulations for supply of medical products, pharmacies should be supplied with medicaments with a remaining shelf life of no less than ... %, and bacterial preparations of no less than ...%:
60%, 40%
40 %, 20%
80 %, 60%
60 %, 30%
50 %, 40%
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A patient with chronic bronchitis gets glaucine hydrochloride at a pharmacy. The patient must be warned about the following typical side effect of this drug:
Increased intraocular pressure
Arterial pressure drop
Excitation of the central nervous system
Irregular heartbeat
Allergic skin rash
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Select the reductant required for the determination of arsenic impurity in drugs (method 2):
Sodium sulfite solution
Sodium hypophosphite
Hydrochloric acid solution
Potassium iodide solution
Sodium hydroxide solution
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The amount of temporary disability benefit for pharmacy employees depends on the time in employment: employees with 5 years of service record receive ...%, 5 to 8 years -... %, over 8 years -... %.
60%, 80%, 100% of the average wage
40 %, 50%, 90% of the average wage
10 %, 30%, 50% of the averagewage
20 %, 40%, 50% of the average wage
25 %, 45%, 65% of the average wage
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A pharmacy produces some injection solutions that have to be apyrogenic. Solution of the following substance can be depyrogenized by method of adsorption with activated carbon?
Scopolamine hydrobromide
Glucose
Platyphyllini hydrotartras
Papaverine hydrochloride
Atropine sulfate
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A pharmacy has to prepare a soft drug based on the gel made from inorganic substances. Which of these high-molecular compounds can be used for preparing such a base?
Collagen
Starch
Polyethylene oxides
Cellulose ethers
Bentonites
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A pharmaceutical enterprise produces ointments. What base is applied for production of sulfur ointment simple?
Emulsion
Vaseline
Base 'For ophthalmic ointments'
Polyethylene glycol
Lanolin
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One of the account forms of a pharmacy is the statement of balance (Form 1) which consists of the assets and liabilities. What are the elements of the assets of a pharmacy?
-
Own capital
Current and non-current assets
Borrowed funds
Own and borrowed funds
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Which drug with antagonistic effect can be used to stop bleeding caused by prolonged use of neodicumarinum?
Vikasolum
Aminocapronic acid
Ascorbic acid
Fibrinogen
Etamsylate
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A pharmacy received an order for 2500 ml of isotonic sodium chloride soluti- on. How much sodium chloride and water for injections should be taken to prepare this dosage form?
22,5 g of sodium chloride and 2500 ml of water for injections
100,0 g of sodium chloride and 2400 ml of water for injections
50,0 g of sodium chloride and 2450 ml of water for injections
30,0 g of sodium chloride and 2500 ml of water for injections
25,0 g of sodium chloride and 2500 ml of water for injections
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Powders that quickly enter into a reaction in presence of water and emit carbon dioxide relate to the following group:
Effervescent powder
Powders for oral use
Soluble powder
Powders for external use
Nasal powders
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A patient suffering from allergic rhinitis was prescribed ephedrine in form of nasal drops. The patient has significantly benefited from nasal instillation, and this stimulated him to use the drug every 2 hours. But under these conditions the drug appeared to be ineffective. What is the most likely cause of this phenomenon?
Tachyphylaxis
Allergy
Cumulation
Drug dependence
Idiosyncrasy
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Which anaesthetic, anti-inflammatory, the least harmful for the stomach preparation can be recommended to a patient with exacerbation of rheumatoid arthritis?
Celecoxib
Acetylsalicylic acid
Diclofenac sodium
Indometacinum
Ibuprofenum
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A teenager with hyporexia has been recommended to drink medicinal herbal tea of the following composition: Herba Absinthii, Herba Millefolii. Specify the characteristic microscopic features of Artemisia absinthium, which indicate its presence in the herb mixture:
Branched and capitate hairs
Branched, simple and ciliated hairs
Retor-shaped hairs
T-shaped hairs along the leaf edge
Simple and capitate hairs
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A laboratory received some herbal raw material for analysis. The plant had flowerheads up to 4 cm in diameter, the marginal flowers were agamic, blue, funnel-shaped; the inner flowers were bisexual, purple, tubular. What plant are these features typical for?
Solidago virgaurea
Polygonum persicaria
Scutellaria baicalensis
Viola tricolor
Centaurea cyanus
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Spesify the type of the following liniment: Ol. Helianthi 7,4 Sol. Ammonii caustici 25 ml Ac. Oleinici 0,1 M.f. linimentum D.S. To be rubbed in.
Liniment-suspension
Liniment, emulsion w/o
Combined liniment
Liniment, emulsion o/w
Liniment-solution
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During the combined pharmacotherapy a patient with peptic ulcer presented with blackcoloured feces. What drug might have caused such change?
Metronidazole
Bismuth subcitrate
Actovegin
Ranitidine
Omeprazole
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A female patient in the first trimester of pregnancy has been diagnosed with acute pyelonephritis. What is the antibiotic drug of choice for treating this patient?
Norfloxacin
Amikacin
Amoxicillin
Chloramphenicol
Gentamicin
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A man with a long history of chronic hepatitis has been diagnosed with pneumonia. Which of the following antibacterial drugs can be applied in this clinical situation?
Biseptol
Rifampicin
Vancomycin
Tetracycline
Amoxicillin
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A pharmaceutic plant producing aerosol forms uses liquefied gases as propellents. Which of the following substances relates to the group of liquefied gases?
Nitrogen
Nitrous oxide
Methylene chloride
Freons
Ethylene chloride
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A patient fell ill with severe pneumonia was prescribed ceftriaxonum once a day. Prescription of ceftriaxonum once a day connected with the fact that the drug:
Slowly eliminated from the body
Pluripotential
Accumulates in the lungs
Has bactericidal effect
Poorly absorbed from the injection site
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A patient with moderately severe pneumonia has been administered ceftriaxone 1 time per day. The drug should be taken once a day due to the following properties:
Slow excretion
Poor absorption from the injection site
Presence of bactericidal action
Wide range of action
Cumulative ability
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Which of the following is the drug of choice for bronchial asthma attacks prevention?
Drotaverine
Salbutamol
Cromolyn sodium
Diphenhydramine hydrochloride
Ambroxol
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A pharmaceutist is preparing an ointment under aseptic conditions on the sterile ointment base - composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technology of ointment preparation is typical for the following substance:
Thiamine chloride
Sodium sulfate
Pilocarpine hydrochloride
Sodium chloride
Benzylpenicillin sodium salt
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Oxidation of some toxins within the body results in generation of compounds that increase their toxicity. Thus, due to the oxidation of heptachlor in the body the folowing compound is formed:
Heptachlor oxide
Carbon monoxide
Heptachlor epoxide
Carbon dioxide
Hexachlorocyclohexane
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Company’s activity aimed at planning, organization and control of physical movement of materials and finished goods from the production site to the place of their utilization for the purpose of covering the consumer needs and gaining profit, is called:
Management
Demand
Advertising
Marketing
Supply
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A pharmaceutist made 10 powders containing atropine sulfate at a rate of 0,00005 pro dose. What trituration did he use?
1:10
1:100
1:20
1:50
1:1000
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In course of isoniazid identification a pharmacy analyst boiled thoroughly the substance with 2,4-dinitrochlorobenzene. The substance turned yellow, after adding alkaline solution it turned first violet and then brownish-red. As a result of this reaction the following aldehyde derivative is produced:
Hexanic
Glutamic
Glutaconic
Gluconic
Glyoxylic
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In order to verify identity of tropan derivatives, Vitali’s reaction is applied. For that purpose the medications should be first decomposed with nitric acid and then treated with alcoholic solution of potassium hydroxide and acetone. What effect will be observed?
Setting of white precipitate
Setting of black precipitate
The solution will turn green
Emission of gas bubbles
The solution will turn purple
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A pharmaceutical factory produces herbal juice out of fresh raw material. What operation should be performed at the stage of juice purification?
Filtration
Adsorption
Crystallization
Sedimentation
Heating followed by quick cooling
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Absorption of tetracycline preparations will be reduced when they are administered simultaneously with antacids. This is an example for:
Pharmacokinetic incompatibility
Functional drugs antagonism
Drugs synergism
Pharmaceutical incompatibility
Pharmacodynamic incompatibility
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A pharmacy got an order for manzanita decoction and hexamethylenetetramine. A pharmacist cancelled it with a stamp 'Invalid prescription'. What is the reason for the incompatibility?
Eutectic
Moisture-repellant
Insolubility
Deposition
Oxidization
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What substance will impede reaction of iodoform test aimed at detection of ethyl alcohol in the biological material?
Acetone
Formaldehyde
Phenol
Isoamyl alcohol
Methanol
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A 24-year-old patient has been suffering from diabetes mellitus type I for 8 years. Diabetic nephropathy provoked development of symptomatic arterial hypertension. Which of the folowing drugs is indicated for long-term therapy?
Dichlothiazide
Enalapril
Propranolol
Clonidine
Dibazol
‹ Назад
Далі ›
Analgin substance has been sent for analysis. What method allows to evaluate quantitative content of analgin?
Iodometry
Acidimetry
Alkalimetry
Permanganatometry
Chelatometry
‹ Назад
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A pharmaceutist prepares internal drops with the following formulation: 5 ml of adoniside, 10 ml of valerian and lily-of-the-valley tincture each, 0,1 g of menthol, 2,0 g of potassium bromide. It will be efficient to dissolve potassium bromide in the following substance:
In the mixture of tinctures
Potassium bromide should be added into the selling vial last of all
In the valerian tincture
In the lily-of-the-valley tincture
In the adoniside
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Далі ›
A pharmaceutist is preparing vaginal suppositories by method of pouring. Which hydrophilic base can he use for this purpose?
Butyrol
Polyethylene oxide
Vitepsol
Cocoa butter
Hard fat
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Treatment course of essential hypertension includes diuretics. Which diuretic DOES NOT NEED to be combined with potassium preparations?
Ethacrynic acid
Dichlothiazide
Clopamide
Furosemide
Triamteren
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A pharmacy store was supplied with 100 packs of a product listed as Nitroglycerine. With regard to its physicochemical properties this preparation should be rated among the following drug group?
Volatile substances
Explosive substances
Highly inflammable substances
Explosion hazardous substances
Combustible substances
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During an operation a dentist needs to reduce salivation in a patient. The dentist has to use a drug of the following pharmacological group:
Muscarinic receptor blockers
Muscarinic cholinomimetics
Muscarinic and nicotinic cholinomi-metics
Adrenomimetics
Adrenoceptor blocker
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A patient with hypertensive crisis received an injection of ganglionic blocker benzohexonium. What side effect might be expected after the drug injection?
Central nervous system depression effect
Withdrawal (abstinence) syndrome
Taste violation
Orthostatic hypotension
Diarrhea
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Pharmaceutical chemistry studies methods of drug synthesis. Interaction of anesthesin with beta-diethylaminoethanol in presence of sodium alcoholate with following acidation with hydrochloric acid results in origination of:
Procaine hydrochloride
Tetracaine hydrochloride
Xycain
Procainamide hydrochloride
Trimecaine hydrochloride
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A pharmacy procured common origanum. What drying conditions should be applied for producing high quality crude drug?
35 - 40oC
70 - 80oC
50 - 60oC
60 - 70oC
80 - 90oC
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For accounting business transactions carried out in a pharmacy the synthetic accounts are used. Their list is given in the Chart of Accounts. Balances of the I, II and III account classes are used for completion of the following document:
Liabilities
First section of the liabilities balance sheet
Profit and Loss Account
Assets
Fourth section of the liabilities balance sheet
‹ Назад
Далі ›
An interhospital pharmacy got an order from a surgical department for a depolarizing muscle relaxant for surgical interventions. What drug was ordered?
Atropine sulfate
Methacin
Dithylinum
Hygronium
Nicotine
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A patient who has taken phenobarbi-tal for a long time was prescribed diclofenac sodium. However the anti-inflammatory effect of diclofenac appeared to be less than expected due to the pharmacokinetic interaction of these drugs. Such interaction might be the result of the following processes:
Decelerated drug metabolism in liver
Accelerated drug metabolism in liver
Change of receptor sensibility
Increased drug dosage
Reduced protein concentration in plasma
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Далі ›
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