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A pharmaceutist prepared powders including extract of belladonna in the amount of 0,015 per dose. For ten doses he had to take the following amount of dry extract:
0,15 g
0,015 g
1,5 g
0,3 g
0,03 g
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A pharmaceutical company focuses on selling a diverse range of products covering different customer groups and regions. What kind of organizational structure is typical for such company?
Centralized
Functional
Bureaucratic
Divisional
Decentralized
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A pharmaceutical company produces cordiamin solution. During the quality control its quantitative content was determined by means of refractometry. For this purpose an analytical chemist measured:
Angle of rotation
Viscosity
Intensity of absorption
Density
Index of refraction
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Which of the following drugs is used for thrombolytic therapy in case of myocardial infarction?
Heparin
Ticlopidine
Phenylinum
Acetylsalicylic acid
Streptokinase
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On the 4th day of treatment with indomethacin a 55-year-old patient developed gastric bleeding as a result of ulceration of the gastric mucosa. Ulcerogenic effect of this drug is due to a decrease in activity of the following enzyme:
Prostacyclin synthetase
Cyclooxygenase-1 (COX-1)
Thromboxane synthetase
Lipoxygenase (LOX)
Cyclooxygenase-2 (COX-2)
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A patient complaining of dry mouth, photophobia and blurred vision has been delivered to the admission ward. Objectively: the skin is hyperaemic, dry; mydriatic pupils and tachycardia are present. He has been diagnosed with belladonna alkaloids intoxication. Which of the drugs should be given as an antidote?
Aceclidine
Dipiroximum
Arminum
Pylocarpine
Neostigmine
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To stop the delusions and hallucinations in a schizophrenic patient a doctor administered aminazine. What is the mechanism of antihypoxic action of this drug?
Inhibition of cholinergic processes in the CNS
Inhibition of adrenergic processes in the CNS
Stimulation of adrenergic and dopaminergic processes in the CNS
Inhibition of dopaminergic processes in the CNS
Stimulation of cholinergic processes in the CNS
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During a surgical operation the muscle relaxant tubocurarine chloride was used. What antagonist drug should be injected in order to allow the patient to breathe independently?
Dithylinum
Веnzohexonium
Neostigmine
Cytitonum
Aethimizolum
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A patient came to a drugstore and ordered cowberry leaves. Which of the available herbal raw materials can be offered as a substitute?
Radix Taraxaci officinalis
Folium Uvae ursi
Herba Achilleae millefolii
Rizoma et radix Sanquisorbae officinalis
Rizoma Calami
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A pharmaceutist has prepared a tincture of althaea root. What is the proportion of herbal raw material and extractant?
1:10
1:400
1:30
1:20
1:100
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An analytical chemist working at a pharmacy identifies oxacillin sodium salt. As a reagent he uses hydroxylami-ne hydrochloride solution in presence of sodium hydroxide solution and copper nitrate solution. What structural fragment of a drug molecule can be detected by means of these reagents?
Thiazolidine cycle
Furan cycle
Isoxazole cycle
Beta-lactam cycle
Thiadiazole cycle
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Diethyl ether relates to simple ethers. Prior to its identification by using the boiling temperature an analytical chemist must ensure that there are no:
Reducing substances
Peroxides
Carboxylic acids
Alcohols
Non-volatile residue
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In order to detect peroxides in the anesthetic ether an analytical chemist should use the following reagent:
Sodium hydroxide
Potassium permanganate
Potassium chloride
Sodium thiosulfate
Potassium iodide
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A syrup contains 82 parts of sugar syrup; 1 part of KJ (KBr); 12 parts of liquid thyme extract and 5 parts of 96% ethanol. What is this medicine called?
Cholosasum
Pertussinum
Ambroxol
Broncholytin
Licorice syrup
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A pharmaceutical enterprise that has achieved high sales rates and customers’ recognition will reach the highest profit at the following stage of the product life cycle:
Development
Decrease
Market penetration
Maturity
Growth
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A pharmaceutic plant producing ointments can use the following equipment at the packing stage:
Disc machines
Rezepin automatic machine
Rotary machines
Eccentric machines
Screw and piston dosing machines
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Aerosol workshop of a pharmaceutic plant uses propellents of different groups. What propellents relate to the group of compressed gases?
Freons
Vinyl and methyl chloride
Nitrogen, nitrous oxide, carbon dioxide
Methylene chloride, ethylene chloride
Propane, butane, isobutane
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An analytical laboratory received calcium gluconate for analysis. What method is used for its quantification?
Mercurimetric determination
Bromatometry
Chelatometry
Nitritometric determination
Iodometry
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Which preparation is the specific antidote in case of intoxication with iron preparations?
Bemegridum
Atropinum
Deferoxamium
Protamine sulfate
Penicillamine
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A pharmaceutist prepared solution of ethacrydine lactate. What is the peculiarity of this substance dissolving?
Dissolving in hot water
Dissolving in potassium iodide solution
Dissolving in freshly distilled water
Dissolving in cold water
Grinding in a mortar with water
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A pharmacy produces compounded drugs. What kinds of internal control of drugs production are required?
Written, physics and chemical
Written and sell control
Written, organoleptic, sell control
Written, interrogatory, sell control
Written, qualitative and quantitative analysis
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A pharmacy analyst can verify presence of iron cation (II) in a drug formulation by means of the following solution:
Ammonium sulfide
Sodium chloride
Potassium bromide
Sodium phosphate
Magnesium sulfate
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A pregnant woman fell ill with severe pneumonia. Which of these antimicrobials should be administered to this patient?
Ofloxacin
Tetracycline hydrochloride
Cefotaxime
Biseptol
Gentamicin sulfate
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A pharmacy manager is working out a schedule for a pharmaceutist who is responsible for prescription reception and drug serving out. What is the weekly working time for one employee?
38 hours
36 hours
30 hours
40 hours
Irregular working week
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A pharmaceutist was on a business trip. What is the deadline for submitting a travel expense report?
Ten working days after returning from a trip
Four working days after returning from a trip
Three working days after returning from a trip
A week after returning from a trip
There is no deadline
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An advance holder (accountant) was given some money from the cash fund of an enterprise for purchase of office accessories. After the cash advance the advance holder must submit the complete application of funds statement no later than:
Such term isn’t established
One week
Third banking day
Ten working days
Five working days
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A pharmacy selling officinal drugs is a successful participant of the pharmaceutical market. Specify the business transaction which is qualified as pharmacy revenue:
Writing-off of the cost of goods sold
Receipt of advance payment made by a customer
Proceeds of a structural subdivision of a pharmacy
Tax charge
Salary accounting
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A pharmacy provides its customers with officinal medicines. Specify the business transaction which is qualified as pharmacy expenses:
Personal income tax
Pharmacy proceeds
Write-off of cost of goods sold
Proceeds of a structural subdivision
Posting of goods
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Medicinal plant Rhamnus cathartica is used as a laxative. What part of this plant is used as herbal raw material?
Roots
Leaves
Fruits
Rind
Shoots
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When the glucose is heated with the copper-tartrate reagent (Fehling’s reagent) the brick-red precipitate settles down. It indicates presence of the following group:
Aldehyde
Etherific
Carboxyl
Amide
Ketonic
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For the purpose of sales stimulation a pharmaceutical wholesale company grants its customers a discount according to the social contract and on condition of their loyalty. Specify the type of discount:
Discounts for quantity of purchased goods
Bonus
Seasonal
Dealer
-
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Before accepting the goods by a pharmacy, they should be checked for quantity and quality. If there is no discrepancy, the pharmacy issues a warrant for receipt of goods. This warrant is valid for:
10 days
3 months
20 days
15 days
1 year
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A patient got intoxicated with an unknown substance. Test of biological material revealed pH=2,0-3,0. The chemico-toxicological analysis should be carried out for the following group of substances:
Mineral acids or large amounts of organic acids
Alkalis
Alkali metal salts
Ammonia
Weak organic acids and heavy metal salts
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One of the quality indicators for finished ampoules is lack of residual stress in the glass. Which operation at the stage 'Preparation of ampoules to be fi-lled'eliminates this imperfection?
Ampoule drying
Capillary opening
Ampoule washing
Ampoule annealing
Ampoule sterilization
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Companies producing injectable dosage forms apply different methods of ampoule sealing. Sealing against a jet of inert gases (nitrogen, argon, carbon dioxide) is suitable for the following injection solutions:
Hydrolytically unstable
Easily oxidable
Photosensitive
Viscous
Thermostable
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Quality control of tablets produced at a pharmaceutical enterprise involves quantitative determination of such subsidiary substances as talc and aerosil. What method is applied for such determination?
Titrimetric
Chromatographic
Photocolorimetric
Spectrophotometric
Gravimetric
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A 6-year-old child with pneumonia has been administered an antibiotic. After treatment the child lost his hearing. What group of antibiotics might have caused this complication?
Aminoglycosides
Cephalosporins
Natural penicillins
Semi-synthetic penicillins
Macrolides
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A 52-year-old patient had myocardial infarction and was discharged from the hospital after the stationery treatment. What daily dose of acetylsalicylic acid should be administered in order to prevent thrombosis?
1000 mg
500 mg
50 mg
100 mg
200 mg
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A woman died from pesticide poisoning as a result of processing of agricultural crops. Measurement of organophosphorous compounds in the extracts of biological material should be started with the following test:
Test for methoxy or ethoxy groups
Test for the presence of chlorine atom
Test for the phosphate ion
Test for the presence of a sulfur atom
Biochemical assay
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In the medical practice this compound is used as a disinfectant. In case of intoxication with this compound the patient’s urine turns olive or olive-black. Specify the compound:
Iodoform
Ethyl ether
Isoamyl alcohol
Phenol
Ethyl benzoate
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In order to identify a drug an analytical chemist of the State Inspectorate for Quality Control of Medicines carries out the reaction with ninhydrin solution. Specify the drug to be identified:
Ascorbic acid
Streptocide
Methionine
Cortisone acetate
Paracetamol
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A pharmaceutist prepared suppository mass with novocaine and cocoa butter, but it turned out to be crumbling. What substance to be added to form a plastic mass:
Paraffin
Vaseline
Anhydrous lanolin
Hydrous lanolin
Wax
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A pharmaceutist has to sterilize 400 ml of calcium gluconate solution for injections. Specify the time of autoclave sterilization of the solution at 120°C:
20 minutes
15 minutes
10 minutes
30 minutes
12 minutes
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Anesthesin relates to substances with local anesthetic activity and is a derivative of the following acid:
Para-aminobenzoic
Para-aminosalicylic
Para-chlorbenzoic
Para-aminophthalic
Para-aminobenzolsulfonic
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According to the State Pharmacopoeia of Ukraine, in order to test a substance for the highest level of magnesium impurities an analytical chemist must use the following solution:
Hydroxyquinoline
Benzaldehyde
Pyridine
Formaldehyde
Resorcin
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Select a reagent that should be applied by an analytical chemist in order to detect alkaloids in the herbal raw material:
Bromine water
Dragendorff reagent
Alkaline solution
Stahl’s reagent
Trim-Hill reagent
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Preparations of sorrel roots can have both a laxative and astringent effect. This is due to the presence of the following biologically active substances:
Flavonoids and essential oils
Coumarins and phenol glycosides
Essential and fatty oils
Iridoids and vitamins
Anthracene derivatives and tannins
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Emodin, an anthracene derivative, haspurgative effect. Large quantities of anthracene-derived groups of emodin are contained in the fruits of the following plant:
Elder (Sambucus)
Buckthorn
Blackcurrant
Alder buckthorn (Frangula alnus)
Blueberry (Vaccinium myrtillus)
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A pharmacy manager is writing the monthly 'Inventory report'. What business transactions should be represented in the expenditure item of the report?
Drug sales
Herbal raw material purchases
Extra-evaluation of laboratorypackaging works
Payroll payment
Amortization charged to operation
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A pharmacy has a license for selling narcotic drugs. The warrant for the receipt of these drugs from the pharmacy warehouse is valid for:
No longer than 5 calendar days from the date of issue
No longer than 1 calendar days from the date of issue
No longer than 10 calendar days from the date of issue
No longer than 1 year from the date of issue
No longer than 3 months from the date of issue
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Which of the pharmacy departments is responsible for checking the quantity and quality of received goods, their storage and dispensing to other departments?
Department of over-the-counter drugs
Inventory department
Department of curative cosmetics
Compounding and production department
Department of finished dosage forms
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The possible admixture in the crop of raw coltsfoot leaves (Tussilago farfara) is the leaf of:
Common plantain
Marshmallow (Althaea officinalis)
Primula officinalis
Cotton burdock (Arctium tomentosum)
Nettle
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In order to determine the purity a drop of lavender essential oil was applied on a strip of filter paper and warmed up in the stream of warm air. Some time later the stain increased in diameter. What impuri- ty substance was found in the lavender oil?
Fatty or mineral oil
Phenol
Ethanol
Diethyl ether
Acetone
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A pharmacy received a batch of raw material - chamomile flowers. How should this material be stored?
According to the list A requirements
As a narcotic raw material
In a light room
According to the list B requirements
Separately from all other kinds of raw material
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A patient acquired mint leaves at a pharmacy. What recommendations regarding infusion of this herbal raw material must be given by the pharmaceutist?
The infusion is to be prepared on an open fire
The extract is to be immediately filtered after infusing
The infusion is to be prepared in a tightly closed vessel
The infusion is to be prepared at room temperature
The extract is to be artificially cooled 15 minutes after infusing
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A patient has been administered a solution containing boric acid and camphor. What solvent should his doctor prescribe in order to prevent physical incompatibility?
Ethyl alcohol 40%
Sunflower oil
Purified water
Ethyl alcohol 70%
Glycerol
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A patient has chronic pancreatitis with apparent presentations of pancreatic exocrine hypofunction. Which of the following drugs would be the most appropriate in this case?
Оmерrаzоlе
Dе-Nоl
Drotaverine
Acidin pepsinum
Раncreatinum
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A patient got an injection of 0,25% novocaine solution for the purpose of anaesthetization. Suddenly the patient has presented with red spots, intense sweating, tachycardia, bronchospasm, edema of nasal mucous membrane. What is the cause of this complication?
Abstinence syndrome
Delayed allergy
Local irritation
Immediate allergy
Tachyphylaxis
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A 15-year-old patient has been first diagnosed with type I diabetes mellitus. Which antihyperglycemic drug should be administered in this case?
Glibenclamide
Insulin
Metformin
Diabetone
Glurenorm
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A patient with gastric ulcer has been administered omeprazole. What is its mechanism of action?
HCl neutralization
Inhibition of H+K+-ATPase
Stimulation of mucus production
Blockade of histamine H2 receptors
Blockade of M-cholinergic receptors
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A manufacturing company initiates changes to the package insert of a drug aimed at limitation of its use. What type of marketing is used by the company in this case?
Stimulating
Remarketing
Counteractive
Conversion
Synchromarketing
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When developing a new drug a manufacturer may apply different strategies of brand use. If a company uses one brand name for all of its products, such strategy is called:
Individual brands
Multi-brand approach
The combination of brand name with an individual drug brand
Brands for individual drugs
Group brands
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A doctor prescribed his patient an emulsion of olive oil which includes anesthesin. To incorporate anesthesin into the emulsion it must be dissolved:
In the purified water
In the finished emulsion
In the alcohol, and then added to the primary emulsion
In the primary emulsion
In oil before preparing the emulsion
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The patient has been prescribed Lini-mentum Rosentali. It is composed of:
Sunflower oil, ammonia, oleic acid
Chloroform, methyl salicylate, turpentine
Paraffin, alcohol, chloroform, iodine
Castor oil, calcium chloride, alcohol
Iodine, potassium chloride, glycerin
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Injection solutions of salts derived from weak acids and strong bases require stabilization. What stabilizers are used for these solutions?
0,1 M acid chloride solution
Buthylhydroxytoluene
Trilon B
0,1 M sodium hydroxide solution
Ascorbic acid
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A pharmaceutical plant produces suppositories. What is the best method for their manufacturing in industrial quantities?
Pressing
Stamping
Pumping-out
Lyophilization
Outpouring
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О-methylation is an important way of biotransformation of organic substances in the body. Compounds subject to О-methylation should contain:
Nitro groups
Thiol groups
Phenol groups
Carboxyl groups
Amino groups
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A pharmaceutist prepares a suspension ointment. What substance is soluble in water, but should be incorporated into the dermatological ointments as a suspension?
Resorcinol
Potassium iodide
Sulfacyl sodium
Furacilin
Zinc oxide
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It is necessary to analyze herbal raw material in form of black glossy drupes 6-8 mm in diameter, with a large, firm, globular, light brown kernel containing one seed. The drupes have sweet and slightly astringent taste. This herbal raw material should be identified as fruits of:
Black chokeberry
Blueberry
Buckthorn
Bird cherry
Hawthorn
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Method of gas-liquid chromatography is often applied for identification and quantitative determination of toxicologically meaningful substances. Substances can be placed into the chromatograph dispenser in the following aggregate states:
Gaseous
Gaseous and solid
Liquid and gaseous
Liquid
Liquid and solid
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Which of the following non-steroid anti-inflammatory agents has the least harmful effect on the mucosa of the gastrointestinal tract?
Nimesulide
Acetylsalicylic acid
Piroxicam
Indomethacin
Diclofenac
‹ Назад
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Which drug is used for thrombolysis in case of acute myocardial infarction?
Acetylsalicylic acid
Alteplase
Pentoxifylline
Fraxiparine
Heparin
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When doing calculations to determine the limit of the cash balance, an accountant must specify the actual amount of cash receipts. What time period should be taken into account?
10 days prior to calculation
Six months prior to calculation
Three months prior to calculation
1 year prior to calculation
7 days prior to calculation
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A doctor gave a prescription for the tincture of digitalis with hydrochloric acid. What is the reason for their incompatibility?
Gassing
Change in odour
Change in colour
Hydrolysis (with no visible changes)
Precipitation
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At the initial stage of establishing a pharmaceutical enterprise the internal disciplinary regulations should be adopted. One of the primary matters is the duration of the lunch break for the employees. According to the Labour Code of Ukraine, the break duration must be as follows:
Up to 2 hours
Not less than 3 hours
Up to 1 hour
2,5 hours
-
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A woman asked a pharmaceutist to dispense an antipyretic for an 8-month-old child. Which drug should be recommended?
Indomethacin
Acetylsalicylic acid
Diclofenac sodium
Paracetamol
Piroxicam
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A 70-year-old patient consulted a doctor about elevated arterial pressure. He has a history of benign hyperplasia of prostate. What drug should be administered in this case?
Doxazosin
Ем^ні
Propranolol
Diltiazem
Losartan
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Having ascertained that the quality of raw material meets the requirements of the analytical normative documentation the quality control department should issue a document. Specify this document:
Certificate of analysis
Pharmacopoeia entry
Request
Standard
Order
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A pharmaceutist revealed incompatibility in a prescription for powders with ascorbic acid and hexamethylene tetrami-ne. What process takes place when these components are combined?
Adsorption
Immiscibility
Isolation of crystallization water
Mixture dampening
Eutectic
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Efficiency of aerosol therapy is to a considerable extent determined by the size of disperse particles. What factor determines the size of aerosol particles during dispersion of an aerosol?
Percentage of phase, filling temperature
Exit port diameter, propellent vapour pressure
System homogeneity, dispersion velocity
Reduction range, container quantity
Fractional composition, containers filling method
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Prior hydrolysis is necessary in case of quantitative determination of the following drug by the nitritometric titration:
Paracetamol
Procaine hydrochloride
Dicaine
Sodium p-aminosalicylate
Anesthesin
‹ Назад
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A pharmacy plans to purchase and retail goods of different stock record units. Which group of goods does VAT reduction apply to?
Baby food
Curative cosmetics
Optics
Medicaments
Perfumes
‹ Назад
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An analytical chemist determines the admixture of sulphates in the boric acid. What is the main reagent to be added?
Barium chloride
Sodium sulphide
Silver nitrate
Ammonium oxalate
Potassium ferrocyanide
‹ Назад
Далі ›
Recommend a patient with acute bronchitis a mucolytic drug that facilitates expectoration:
Glaucine
Drotaverine hydrochloride
Acetylcysteine
Loratadine
Diclofenac sodium
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Далі ›
A patient with atopic dermatitis presented at the hospital. Which drug with anti-inflammatory and antiallergic effect should be administered to this patient?
Oxytocin
Prednisolone
Insulin
Retabolil
Aethamidum
‹ Назад
Далі ›
A patient with atherosclerosis has been administered an anti-atherosclerotic agent. Specify this drug:
Ascorbic acid
Phenylbutazone
Phenofibrate
Pyracetam
Dexamethasone
‹ Назад
Далі ›
A patient after bee’s stings has angi-oedema (Quincke’s edema). Which drug should be immediately inject to eliminate this condition?
Platyphyllini hydrotartras
Epinephrine hydrochloride
Sodium chloride
Anaprilinum
Atropine sulfate
‹ Назад
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A pharmacy received a batch of medicines from a pharmacy depot. Specify the drug subject to the controlled substance inventory in pharmacies:
Dicaine
Analgin
Paracetamol
Acetylsalicylic acid
Novocaine
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A pharmaceutical company conducted an age-specific segment analysis of the regional antihistamine market. It revealed the lack of antihistamines for children. The company will consider this segment as:
Market door
Market share
Segment requiring further research
Market niche
Unattractive segment
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The manufacturing pharmaceutical company 'Elema'set up its own corporate pharmacy. In this case, it uses the following distribution channel:
Second level
First level
Third level
Fourth level
Zero level
‹ Назад
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A pharmacy received some medicines from the warehouse. What medicine is subject to the stocktaking in the pharmaceutical institutions?
Analginum
Codeine
Aminalonum
Corvalolum
Butadionum
‹ Назад
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A pharmacy sells drugs by retail. Omnopon relates to the following group of controlled drugs:
Potent
Psychtropic
Narcotic
Toxic
General sale list
‹ Назад
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A patient with cholelithiasis should be administered the following drug for the dissolution of cholesterol gallstones:
Gamma-aminobutyric acid
Acetylsalicylic acid
Citric acid
Ursodeoxycholic acid
Mefenamic acid
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Далі ›
A patient with acute heart failure and intolerance of cardiac glycosides has been given an injection of dobutamine. What is the mechanism of its action?
Stimulation of α- adrenoceptors
Stimulation of M-cholinergic receptors
Blockade of K+-, Na+-ATPase
Stimulation of β₁-adrenoceptors
Inhibition of phosphodiesterase
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Далі ›
One of the methods of quantitative analysis of active substances in the raw material is the biological standardization. It can be applied with the following group of biologically active substances:
Tannins
Fatty oils
Mucilages
Alkaloids
Cardiac gliycosides
‹ Назад
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In the process of pressing the tablets adhere to the pressing tool. The technological error is the lack of:
Diluents
Adhesive substances
Dyes
Lubricants
Disintegrants
‹ Назад
Далі ›
An elderly patient has constipation caused by hypotonia of colon. What drug should be administered to this patient?
Atropine sulfate
Castor oil
Novocaine amide
Sodium sulfate
Bisacodyl
‹ Назад
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A forensic medicine laboratory received some biological material. It should be analyzed for the presence of trichlorfon and dichlorvos. For their isolation a toxicologist infuses them with:
Chloroform
Water alkalized with ammonia solution
Water acidified with sulfuric acid
Propanol acidified with oxalic acid
Ethanol acidified with oxalic acid
‹ Назад
Далі ›
A chemical department produces alcohol solution of boric acid. What filters are used for filtration of this solution?
Membrane filter
Bag filter
Pressure filters
Paper filter
Nutsch filter
‹ Назад
Далі ›
A pharmacy received a prescription for preparation of dermatological ointment with benzylpenicillin. Specify the type of ointment that necessary to prepare:
Hydrophilic ointment
Liquid ointment
Suspension ointment
Alloy ointment
Combined
‹ Назад
Далі ›
A pharmacy received a prescription for powders with doctor’s instruction to dispense powders in gelatin capsules. Which of the following substances is included in the composition of these powders?
Ethacridine lactate
Streptocide
Glucose
Magnesium oxide
Diphenhydramine
‹ Назад
Далі ›
In course of pharmacotherapy of bronchitis a patient was found to have dyspeptic disorders, photodermatitis, liver dysfunction. Which of the prescribed drugs might have caused these manifestations?
Ascorbic acid
Acetylcysteinum
Doxycyclin
Codeine phosphate
Paracetamolum
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From the pharmaceutical stock select an anticholinesterase drug to be administered to the patients with atony of the intestine and urinary bladder in the postoperative period:
Dithylinum
Benzohexonium
Atropine sulfate
Proserin
Phosphacolum
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Most alkaloids are isolated from the biological material by means of polar solvents. Which of the listed alkaloids is isolated by the way of distillation with water vapour?
Strychnine
Quinine
Atropine
Coniine
Cocaine
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Comparative analysis of the performance of two pharmacies showed that the trade stock in terms of days was 20 and 30 days respectively. Which of these indicators is NOT USED for calculating the trade stock?
Wage fund
The left-over goods in terms of settlement prices
The rate of trade mark-up
Sales volume
Turnover
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A pharmacy received a batch of drugs from a wholesale firm. What document signed by an authorized person is the basis for further sale of drugs?
Register of medicinal products accepted for sale
Information on state registration
Quality certificates
National register of medicinal products
Opinion letter of the territorial inspectorate
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A patient who has been suffering from gastric diseases for a long time is found to have hyperchromic anemia. Which of the following drugs is applied for this pathology treatment?
Ferrum Lek
Cyanocobalamine
Ascorbic acid
Unitiol
Охуferriscorbone
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A phytopreparation 'Flacarbi-num'has spasmolytic, anti-inflammatory and antiulcer effect. This preparation is produced out of the following plant:
Mountain angelica (Aralia mandshuri-ca)
Jacob’s ladder blue (Polemonium caeruleum)
Pot marigold (Calendula officinalis)
Licorice (Glycyrrhiza)
Buckeye (Aesculus)
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Specify the reaction to the ester-type drugs that is tolerated by the State Pharmacopoeia of Ukraine:
Formation of 3-bromphenol
Formation of iron hydroxamates
Formation of indophenol
Formation of azo dye
-
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Streptocide, sulfacyl sodium, norsulfazole or sulfadimezinum can be identified by means of the reaction to form:
-
Fluorescein
Murexide
Azo dye
Iodoform
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Which of the following drugs can be quantified by an analytical chemist by ceriometry method?
Sodium benzoate
Phenobarbital
Vicasolum
Acetylsalicylic acid
Phenyl salycylate
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Three founders set up a business entity for the wholesale distribution of medicines and healthcare products. Specify the form of such company:
Individual
Public
Unitary
Corporate
Utility
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Pharmaceutical market is in such a situation when there is only one company selling a certain product. Specify the competitive structure of the market:
Pure monopoly market and oligopolistic market
Pure monopoly market
Monopolistic competitive market
Pure competition market
Oligopolistic market
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The founders are going to open a retail pharmacy. What way of business running is stipulated in this case?
Normative
Licence-based
Limited
Free
Without preliminary licencing or registration
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A pharmaceutist prepared 150 ml of Adonis vernalis infusion using dry extract concentrate [1:1] that had to be weighed in the amount of :
22, 5
5,0
15, 0
10, 0
7, 5
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A pharmacy received a prescription: Rp.: Dibazoli0,05 Papaverini hydrochloridi 0,15 Sacchari 2,5 M. fiat pulv. Divide in partes aequales №10. Specify the weight of a single powder dose :
0, 30
0, 25
2, 7
0,27
0, 26
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An analytical chemist determines the quantity of a drug by the method of indirect bromatometry. Which of the following titrated solutions is to be used?
Silver nitrate
Sodium edetate
Sodium nitrite
Sodium thiosulfate
Calcium bromate
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In order to identify a drug an analytical chemist of the State Inspectorate for Quality Control performs a lignin test. Specify this drug:
Streptocid
Analgin
Ascorbic acid
Cortisone acetate
Methionine
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The main active components of hawthorn berries are flavonoids. What is their pharmacological effect?
Tonic and antispasmodic
Laxative and sedative
Diuretic and styptic
Hypotensive and sedative
Antispasmodic and anti-inflammatory
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An analytical chemist working at an analytical laboratory identifies a drug by the sulfite ions according to the requirements of the State Pharmacopoeia of Ukraine. What reagent gets decolorized during this assay?
Potassium nitrate solution
Iodine solution
Ammonia solution
Potassium iodide solution
Iron (III) chloride solution
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An analytical laboratory received 'Aether anaestheticus' for analysis. What reagent should be used for detecting acetone and aldehyde impurities according to the State Pharmacopoeia of Ukraine?
Aqueous solution of potassium iodide
Sodium hydrosulfite solution
Alkaline solution of potassium tetrai-odomercurate
Ammonium solution of argentum nitrate
Hydroxylamine solution
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Compulsory deductions from employee’s salary are made by the accounting department independently. Specify a deduction which can be made only on the grounds of written permit of an employee:
Alimony
Contributions to the Social insurance fund for temporary disability
Superannuation contributions
Contributions to the Social insurance fund for unemployment
Charitable contributions
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Natural persons registered as small business entities with simplified taxation scheme (2 group) have the limit for the annual amount of sales proceeds. Specify the proceeds limit:
1 million UAH
100 thousand UAH
3 million UAH
5 million UAH
750 thousand UAH
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Fatty oil containing unsaturated fatty acids is used for the prevention of atherosclerosis. Specify the herbal raw material used for oil production:
Hawthorn berries
Seeds of flax
Fruits of black chokeberry
Seeds of fennelflower
Fruits of dill
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The ampoule workshop produces solutions for injections. The aminophylli-ne solution for injections relates to the following group of solutions:
Solutions of substances requiring special purification
Solutions are not subject to heat sterilization
Solutions of salts composed of strong bases and weak acids
Solutions of salts composed of weak bases and strong acids
Solutions of easily oxidizable substances
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Phytochemical workshop of a pharmaceutical plant produces biogenic stimulators from different raw materials. Specify the biogenic stimulators of animal origin:
Liquid aloe extract, aloe liniment, plasmolum
Peloidinum, humisolum, torfotum, Fibs pro injectionibus
Liquid aloe extract, aloe liniment, aloe juice, biossedum
Peloidinum, humisolum, torfotum, plasmolum, solcoseryl
Vitreous body, placental suspension for injections, plasmolum, solcoseryl
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The planning of marketing strategy involves two successive stages. What are the stages of the strategic planning process?
Describing the current marketing situation
Budgeting
Making the list of tasks and problems
Developing a program of activities
Defining the mission and goals of a pharmaceutical company
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Benzathine benzylpenicillin is the drug of choice for treating the following disease:
Intestinal infection
Furunculosis
Pneumonia
Syphilis
Angina
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In order to identify ouabain (strophanthine G), a drug from the group of cardiac glycosides, an analytical chemist must prove the presence of a steroid cycle. What acid should be used as a reagent?
Formic
Oxalic
Citric
Sulfuric
Chromotropic
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An analytical laboratory has to analyze ferrous sulfate heptahydrate according to the State Pharmacopoeia of Ukraine. A test portion of the substance should be titrated with the following solution:
Silver nitrate
Sodium edetate
Ammonium thiocyanate
Ammonium cerium sulfate
Potassium bromate
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Urine of an intoxicated person was found to contain ecgonine. This indicates poisoning with the following substance:
Caffeine
Cocaine
Phenacetin
Phenol
Heroin
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A patient with schizophrenia has been administered a neuroleptic. Which of the listed drugs falls into this group?
Morphine
Aminazine
Propranolol
Pyracetam
Celecoxib
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A laboratory received some herbal raw material for analysis. It is a composition of ovoidpointed leaves up to 25 cm long and 20 cm wide; the leaf base is cuneate, the leaf edge is emarginate, The cutting is long and cylindric. The leaf venation is pinnatisect; the midrib and the first-order veins project significantly on the inferior surface of the leaf. The superior leaf surface is dark green, the inferior surface is light green. The plant has a weak narcotic smell. The taste cannot be determined. The plant is poisonous! The described herbal raw material relates to the following plant:
Passiflora incarnata
Chelidonium majus
-
Vinca minor
Datura stramonium
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A pharmaceutist has prepared an emulsion. Specify the way of incorporation of the fat-soluble substances:
They are dissolved in oil
They are dissolved in purified water
They are added to the emulsifier
They are incorporated in undissolved form
They are added to the finished emulsion
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A pharmacy received a prescription for a mixture. What drug substances are incompatible?
Sodium bromide + sodium chloride
Codeine phosphate + extract of Thermopsis
Papaverine hydrochloride + ami-nophylline
Novocaine + diphenhydramine
Phenobarbital + glucose
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The risk can arise from some forms of activity connected with production of goods and services, their selling, commodity-money and financial operations, commerce, implementation of socioeconomic and scientific-and-technical projects. This is the definition for the following concept:
Financial loss
Labour loss
Loss of property
Loss of time
Business risk
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Inventory of human resources at pharmaceutical companies is based on keeping of work record books, employee’s files, personal data sheets T-2. What parameter CANNOT be estimated by the analysis of the above-mentioned date?
Average payroll strength
Staff categories
Data on the staff turnover
Labour market state
Average staffing number
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The equity capital of a pharmacy is 7500 UAH, the liabilities make 2500 UAH. According to the formula of balance calculation given in the Statement of Standard Accounting Practice 2 the amount of pharmacy assets will be as follows:
7 500 UAH
2 500 UAH
12 000 UAH
10 000 UAH
4 000 UAH
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Forensic toxicological analysis of a mineralizate revealed copper. For preliminary determination of copper ions the following substance is used:
Diphenylcarbazide
Plumbum diethyldithiocarbamate
Diphenylamine
Dithizone
Sodium diethyldithiocarbamate
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A patient got intoxicated with nitrites. Nitrites can be detected by means of the reaction of azo-dye formation with the following acid:
Phosphoric
Sulfanilic
Hydrochloric
Sulfuric
Salicylic
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Admixtures can get into the herbal raw material during harvesting, drying and primary processing. Mineral admixtures include:
Metal objects
Other similar plants
Sand, earth, stones
Other organs of the same plant
Droppings of birds and rodents
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Preparations made out of eleutherococcus roots and rhizomes are administered as a tonic and adaptogenic drug. If these preparations cannot be found in a pharmacy, they can be substituted by the analogous preparations made of the following raw material:
Polemonium roots
Elecampane roots
Rhizomes and roots of valerian
Acorus calamus roots
Ginseng roots
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When a certain drug reduces the effect of another drug, such phenomenon is called:
Habituation
Tachyphylaxis
Sensibilization
Antagonism
Potentiation
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The ability of drugs to accumulate in the patient’s body is called:
Allergy
Synergism
Habituation
Antagonism
Cumulation
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As main reagent in test for phosphates admixtures the Ukrainian State Pharmacopoeia recommends to use:
Cupric tartrate
Hypophosphite
Acetylacetone
Thioacetamide
Sulfomolybdenum
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A patient has been administered a spasmolytic from the group of muscarinic receptor antagonists as a part of the complex treatment for renal colic. Specify this drug:
Dithylinum
Galantamine
Benzohexonium
Neostigmine
Atropine
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A common method for quantitative determination of drugs from the group of alkali metal halogenides is:
Argentometry
Nitritometry
Permanganatometry
Alkalimetry
Chelatometry
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Treatment of poisonings with inorganic mercury compounds includes the use of the following antidote:
Unithiol
Naloxone
Desferal
Tetacinum-calcium
Dexamethasone
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A patient has been taking isosorbi-de for stenocardia prevention for quite a long time. Now he notes a significant decrease in the effect of the drug. What is this phenomenon called?
Allergy
Tolerance
Physical dependence
Potentiation
Cumulation
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Marketing manager at a pharmaceutical factory is planning its communication policy. Which component of the marketing communication systems has the highest value for one contact?
Periodical advertising
Personal sale
Sales promotion
'Public relations'
TV advertising
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A patient with myocardial infarction has been given an intravenous injection of a direct-acting anticoagulant. Select it among the listed drugs:
Thrombin
Vikasolum
Heparin
Neodicumarinum
Calcium gluconate
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Incoming control is conducted in the course of wholesale and retail trade, such control is carried out during receipt of goods by visual inspection or analysis of drug. Incoming control is carried out by authorized person, which is assigned by:
Head of regional structure
The order of head of territorial inspection
Proprietor of an enterprise
Managers order
State inspection of drugs quality control
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When a pharmacy records goods as received, it normally specifies the amount of the markup intended for expenditure coverage and profit gaining. Give the definition for the markup:
The amount of goods sold
The difference between the sale price and purchase price of goods
The difference between the sales price and markup
Rummage (goods remains) at the end of the month
The difference between the sales price and the customs price
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A pharmacy received a batch of goods from a supplier. What is the main financial document for posting the goods at the pharmacy?
Aquittance
Cash order
Receipts note
Requisition
Goods delivery note
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According to the basic regulations for supply of medical products, pharmacies should be supplied with medicaments with a remaining shelf life of no less than ... %, and bacterial preparations of no less than ...%:
60%, 40%
50 %, 40%
40 %, 20%
80 %, 60%
60 %, 30%
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A patient with chronic bronchitis gets glaucine hydrochloride at a pharmacy. The patient must be warned about the following typical side effect of this drug:
Arterial pressure drop
Excitation of the central nervous system
Allergic skin rash
Irregular heartbeat
Increased intraocular pressure
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Select the reductant required for the determination of arsenic impurity in drugs (method 2):
Sodium hypophosphite
Sodium hydroxide solution
Sodium sulfite solution
Potassium iodide solution
Hydrochloric acid solution
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The amount of temporary disability benefit for pharmacy employees depends on the time in employment: employees with 5 years of service record receive ...%, 5 to 8 years -... %, over 8 years -... %.
25 %, 45%, 65% of the average wage
20 %, 40%, 50% of the average wage
60%, 80%, 100% of the average wage
10 %, 30%, 50% of the averagewage
40 %, 50%, 90% of the average wage
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A pharmacy produces some injection solutions that have to be apyrogenic. Solution of the following substance can be depyrogenized by method of adsorption with activated carbon?
Atropine sulfate
Glucose
Papaverine hydrochloride
Platyphyllini hydrotartras
Scopolamine hydrobromide
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A pharmacy has to prepare a soft drug based on the gel made from inorganic substances. Which of these high-molecular compounds can be used for preparing such a base?
Polyethylene oxides
Starch
Collagen
Cellulose ethers
Bentonites
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A pharmaceutical enterprise produces ointments. What base is applied for production of sulfur ointment simple?
Vaseline
Emulsion
Polyethylene glycol
Lanolin
Base 'For ophthalmic ointments'
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One of the account forms of a pharmacy is the statement of balance (Form 1) which consists of the assets and liabilities. What are the elements of the assets of a pharmacy?
Own and borrowed funds
Own capital
Current and non-current assets
-
Borrowed funds
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Which drug with antagonistic effect can be used to stop bleeding caused by prolonged use of neodicumarinum?
Ascorbic acid
Vikasolum
Fibrinogen
Etamsylate
Aminocapronic acid
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A pharmacy received an order for 2500 ml of isotonic sodium chloride soluti- on. How much sodium chloride and water for injections should be taken to prepare this dosage form?
22,5 g of sodium chloride and 2500 ml of water for injections
25,0 g of sodium chloride and 2500 ml of water for injections
100,0 g of sodium chloride and 2400 ml of water for injections
30,0 g of sodium chloride and 2500 ml of water for injections
50,0 g of sodium chloride and 2450 ml of water for injections
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Powders that quickly enter into a reaction in presence of water and emit carbon dioxide relate to the following group:
Powders for external use
Effervescent powder
Soluble powder
Nasal powders
Powders for oral use
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A patient suffering from allergic rhinitis was prescribed ephedrine in form of nasal drops. The patient has significantly benefited from nasal instillation, and this stimulated him to use the drug every 2 hours. But under these conditions the drug appeared to be ineffective. What is the most likely cause of this phenomenon?
Allergy
Cumulation
Idiosyncrasy
Drug dependence
Tachyphylaxis
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Which anaesthetic, anti-inflammatory, the least harmful for the stomach preparation can be recommended to a patient with exacerbation of rheumatoid arthritis?
Diclofenac sodium
Indometacinum
Ibuprofenum
Celecoxib
Acetylsalicylic acid
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A teenager with hyporexia has been recommended to drink medicinal herbal tea of the following composition: Herba Absinthii, Herba Millefolii. Specify the characteristic microscopic features of Artemisia absinthium, which indicate its presence in the herb mixture:
Branched and capitate hairs
Simple and capitate hairs
Branched, simple and ciliated hairs
T-shaped hairs along the leaf edge
Retor-shaped hairs
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A laboratory received some herbal raw material for analysis. The plant had flowerheads up to 4 cm in diameter, the marginal flowers were agamic, blue, funnel-shaped; the inner flowers were bisexual, purple, tubular. What plant are these features typical for?
Polygonum persicaria
Viola tricolor
Centaurea cyanus
Solidago virgaurea
Scutellaria baicalensis
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Spesify the type of the following liniment: Ol. Helianthi 7,4 Sol. Ammonii caustici 25 ml Ac. Oleinici 0,1 M.f. linimentum D.S. To be rubbed in.
Liniment-suspension
Liniment, emulsion w/o
Combined liniment
Liniment-solution
Liniment, emulsion o/w
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During the combined pharmacotherapy a patient with peptic ulcer presented with blackcoloured feces. What drug might have caused such change?
Omeprazole
Bismuth subcitrate
Ranitidine
Metronidazole
Actovegin
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A female patient in the first trimester of pregnancy has been diagnosed with acute pyelonephritis. What is the antibiotic drug of choice for treating this patient?
Amoxicillin
Norfloxacin
Gentamicin
Chloramphenicol
Amikacin
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A man with a long history of chronic hepatitis has been diagnosed with pneumonia. Which of the following antibacterial drugs can be applied in this clinical situation?
Rifampicin
Vancomycin
Biseptol
Tetracycline
Amoxicillin
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A pharmaceutic plant producing aerosol forms uses liquefied gases as propellents. Which of the following substances relates to the group of liquefied gases?
Ethylene chloride
Methylene chloride
Nitrogen
Nitrous oxide
Freons
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A patient fell ill with severe pneumonia was prescribed ceftriaxonum once a day. Prescription of ceftriaxonum once a day connected with the fact that the drug:
Poorly absorbed from the injection site
Accumulates in the lungs
Slowly eliminated from the body
Has bactericidal effect
Pluripotential
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A patient with moderately severe pneumonia has been administered ceftriaxone 1 time per day. The drug should be taken once a day due to the following properties:
Cumulative ability
Presence of bactericidal action
Slow excretion
Wide range of action
Poor absorption from the injection site
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Which of the following is the drug of choice for bronchial asthma attacks prevention?
Salbutamol
Ambroxol
Cromolyn sodium
Diphenhydramine hydrochloride
Drotaverine
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A pharmaceutist is preparing an ointment under aseptic conditions on the sterile ointment base - composition of vaseline and lanoline at a ratio 6:4. The drug substance is incorporated by suspension type. Such technology of ointment preparation is typical for the following substance:
Pilocarpine hydrochloride
Sodium sulfate
Benzylpenicillin sodium salt
Thiamine chloride
Sodium chloride
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Oxidation of some toxins within the body results in generation of compounds that increase their toxicity. Thus, due to the oxidation of heptachlor in the body the folowing compound is formed:
Heptachlor epoxide
Hexachlorocyclohexane
Carbon monoxide
Carbon dioxide
Heptachlor oxide
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Company’s activity aimed at planning, organization and control of physical movement of materials and finished goods from the production site to the place of their utilization for the purpose of covering the consumer needs and gaining profit, is called:
Management
Marketing
Demand
Supply
Advertising
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A pharmaceutist made 10 powders containing atropine sulfate at a rate of 0,00005 pro dose. What trituration did he use?
1:1000
1:20
1:100
1:50
1:10
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In course of isoniazid identification a pharmacy analyst boiled thoroughly the substance with 2,4-dinitrochlorobenzene. The substance turned yellow, after adding alkaline solution it turned first violet and then brownish-red. As a result of this reaction the following aldehyde derivative is produced:
Hexanic
Glutaconic
Glutamic
Glyoxylic
Gluconic
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In order to verify identity of tropan derivatives, Vitali’s reaction is applied. For that purpose the medications should be first decomposed with nitric acid and then treated with alcoholic solution of potassium hydroxide and acetone. What effect will be observed?
Setting of white precipitate
The solution will turn green
The solution will turn purple
Emission of gas bubbles
Setting of black precipitate
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A pharmaceutical factory produces herbal juice out of fresh raw material. What operation should be performed at the stage of juice purification?
Crystallization
Adsorption
Heating followed by quick cooling
Filtration
Sedimentation
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Absorption of tetracycline preparations will be reduced when they are administered simultaneously with antacids. This is an example for:
Pharmacokinetic incompatibility
Pharmacodynamic incompatibility
Drugs synergism
Functional drugs antagonism
Pharmaceutical incompatibility
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A pharmacy got an order for manzanita decoction and hexamethylenetetramine. A pharmacist cancelled it with a stamp 'Invalid prescription'. What is the reason for the incompatibility?
Insolubility
Deposition
Oxidization
Moisture-repellant
Eutectic
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What substance will impede reaction of iodoform test aimed at detection of ethyl alcohol in the biological material?
Isoamyl alcohol
Formaldehyde
Phenol
Methanol
Acetone
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A 24-year-old patient has been suffering from diabetes mellitus type I for 8 years. Diabetic nephropathy provoked development of symptomatic arterial hypertension. Which of the folowing drugs is indicated for long-term therapy?
Clonidine
Propranolol
Dibazol
Enalapril
Dichlothiazide
‹ Назад
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Analgin substance has been sent for analysis. What method allows to evaluate quantitative content of analgin?
Alkalimetry
Permanganatometry
Iodometry
Chelatometry
Acidimetry
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A pharmaceutist prepares internal drops with the following formulation: 5 ml of adoniside, 10 ml of valerian and lily-of-the-valley tincture each, 0,1 g of menthol, 2,0 g of potassium bromide. It will be efficient to dissolve potassium bromide in the following substance:
In the valerian tincture
In the mixture of tinctures
Potassium bromide should be added into the selling vial last of all
In the lily-of-the-valley tincture
In the adoniside
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A pharmaceutist is preparing vaginal suppositories by method of pouring. Which hydrophilic base can he use for this purpose?
Vitepsol
Cocoa butter
Butyrol
Hard fat
Polyethylene oxide
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Treatment course of essential hypertension includes diuretics. Which diuretic DOES NOT NEED to be combined with potassium preparations?
Dichlothiazide
Clopamide
Triamteren
Furosemide
Ethacrynic acid
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A pharmacy store was supplied with 100 packs of a product listed as Nitroglycerine. With regard to its physicochemical properties this preparation should be rated among the following drug group?
Highly inflammable substances
Explosion hazardous substances
Combustible substances
Volatile substances
Explosive substances
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During an operation a dentist needs to reduce salivation in a patient. The dentist has to use a drug of the following pharmacological group:
Adrenoceptor blocker
Adrenomimetics
Muscarinic cholinomimetics
Muscarinic receptor blockers
Muscarinic and nicotinic cholinomi-metics
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A patient with hypertensive crisis received an injection of ganglionic blocker benzohexonium. What side effect might be expected after the drug injection?
Diarrhea
Taste violation
Orthostatic hypotension
Withdrawal (abstinence) syndrome
Central nervous system depression effect
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Pharmaceutical chemistry studies methods of drug synthesis. Interaction of anesthesin with beta-diethylaminoethanol in presence of sodium alcoholate with following acidation with hydrochloric acid results in origination of:
Trimecaine hydrochloride
Procainamide hydrochloride
Tetracaine hydrochloride
Procaine hydrochloride
Xycain
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A pharmacy procured common origanum. What drying conditions should be applied for producing high quality crude drug?
50 - 60oC
60 - 70oC
80 - 90oC
70 - 80oC
35 - 40oC
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For accounting business transactions carried out in a pharmacy the synthetic accounts are used. Their list is given in the Chart of Accounts. Balances of the I, II and III account classes are used for completion of the following document:
Fourth section of the liabilities balance sheet
Liabilities
Profit and Loss Account
Assets
First section of the liabilities balance sheet
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An interhospital pharmacy got an order from a surgical department for a depolarizing muscle relaxant for surgical interventions. What drug was ordered?
Atropine sulfate
Dithylinum
Methacin
Hygronium
Nicotine
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Далі ›
A patient who has taken phenobarbi-tal for a long time was prescribed diclofenac sodium. However the anti-inflammatory effect of diclofenac appeared to be less than expected due to the pharmacokinetic interaction of these drugs. Such interaction might be the result of the following processes:
Accelerated drug metabolism in liver
Change of receptor sensibility
Decelerated drug metabolism in liver
Increased drug dosage
Reduced protein concentration in plasma
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Далі ›
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