Step 1 - Pharmacy 2020

What titrimetric method of analysis requires the use of both external and internal indicators?

Nitritometry

Argentometry

Complexometric titration

Alkalimetry

Permanganatometry

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A solution contains calcium, barium, aluminium, potassium, and sodium cations. Into this solution a small amount of ammonium hydroxide and alizarin solution was added, which resulted in production of red precipitate. What ion was detected as the result of this reaction?

Sodium

Calcium

Aluminium

Barium

Potassium

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Select an indicator for argentometric determination of chloride ions using the Mohr method:

Diphenylcarbazone

Fluorescein

Potassium chromate

Methyl red

Eosin

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Quantitative determination of copper salts by means of photometric titration should be conducted according to the calibration graph that is built within the following coordinates:

Optical density - wavelength

Light absorption intensity - wavelength

Optical density - temperature

Optical density - concentration

Optical density - liquid layer thickness

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2M solution of HCl was added into the solution being studied, which resulted in formation of white precipitate that turned black when processed with ammonia solution. What cation is present in this solution?

Hg2+

Ag+

Ba2+

Pb2+

Mg2+

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What should be measured during quantitative determination of glucose by means of polarimetry?

Light beam dispersion in the solution

Rotation angle of a polarized light beam

Optical density of the solution

Refractive index

Absorption coefficient of a polarized light beam in the solution

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Concentration of ethyl alcohol in tinctures and some other dosage forms can be determined by means of refractometry. For this purpose the following should be measured:

Angle of total internal reflection of a light beam

Light beam refraction angle

Solution refractive index

Rotation angle of a light polarization plane

Light beam incidence angle

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Ammonium thiocyanate solution was added into the solution being studied. The resulting solution colored red. This analytical effect indicates the presence of the following cation:

Iron(III)

Mercury(I)

Silver

Lead(II)

Mercury(II)

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What reference electrode should be used for potentiometric determination in a solution that contains ammonia and sodium hydroxide?

Silver

Zinc

Glass

Platinum

Silver chloride

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When barium chloride solution was added into the solution being studied, it resulted in a white precipitate that was acidand alkali-insoluble, which indicates that this solution contains:

Iron(II) ions

Permanganate ions

Sulfate ions

Nitrate ions

Chloride ions

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What laboratory glassware is used in titrimetric methods of analysis to measure out a precise volume of a titrant?

Pipette

Burette

Measuring cylinder

Volumetric flask

Measuring glass

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Quantitative content of oxalic acid can be determined by means of permanganatometry. How to determine the equivalence point for this kind of titration?

When titrate changes its color after another drop of working solution is added

With adsorption indicator

With redox indicator diphenylamine

With specific indicator

With pH indicator

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Specify what method of redox titration requires the use of specific indicator - starch - to fix the end point:

Bromatometry

Iodometry

Cerimetry

Nitritometry

Permanganatometry

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To separate cations of the 6th analytical group from cations of the 5th analytical group (acid-base classification), the following is used:

Excess sodium hydroxide solution

Excess ammonia solution

Silver nitrate solution

Excess sulfuric acid solution

Acetic acid solution

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To determine mass-volume fraction of ammonia in a solution, the following solution should be used:

Sodium hydroxide

Hydrochloric acid

Sulfuric acid

Potassium permanganate

Iodine

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Pharmacopoeia reaction to determine benzoate ions requires interaction with the solution of:

Iron(III) chloride

Acetic anhydride

Diphenylamine

Potassium chloride

Resorcin

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What reference electrode can be used in potentiometric analysis of a medicinal substance?

Antimony

Zinc

Glass

Quinhydrone

Silver chloride

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Why is there no group reagent for the cations of the 1st analytical group (acid-base cassification)?

They can form soluble bases

Most of their salts are water-soluble

They belong to biologically important elements

They have large ionic radii

They have close ionic radii

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What working solutions (titrants) are used in Volhard method (precipitation titration)?

KMnO4 and KBrO3

H2SO4 and NaOH

AgNO3 and NH4SCN

Na2S2O3 and K[I3]

HClO4 and KOH

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The third analitycal group of cations (acid-base classification) includes Ca2+, Sr2+, Ba2+. What acid can function as a precipitator agent (group reagent) for these cations?

H2SO4

HNO3

HCIO4

HCI

CH3COOH

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Reaction of sodium ions with potassium hexahydroxoantimonate(V) in neutral medium produces precipitate. Specify the color of this precipitate:

White

Red

Blue

Yellow

Green

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Which compound of those listed below is a condensed arene?

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Specify the Wurtz reaction among those given below:

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Select the formula of diazonium salt:

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Salts and esters of oxalic acid are called:

Oxalates

Urates

Adipates

Succinates

Malonates

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What test is used for identification of uric acid and other compounds with purine nucleus?

Copper mirror reaction

Murexide reaction

Lucas reagent

Silver mirror reaction

Fehling reagent

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Select the compound with both pyrrole and pyridine nitrogen atoms from those given below:

Pyridazine

Theophylline

2-Aminopyridine

Pteridine

Pyrimidine

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What reagent allows distinguishing between maltose (a reducing disaccharide) and sucrose (a non-reducing disaccharide)?

NaOH

FeCl3

K4[Fe(CN6)]

Tollens reagent

Br2

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Specify the name of the alkene given below according to the IUPAC substitutive nomenclature:

3,5-Dimethyl-4-hexene

2,4-Dimethyl-2-hexene

4-Ethyl-2-methyl-2-pentene

2-Ethyl-4-methyl-3-pentene

4-Ethyl-2-methyl-3-pentene

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Cellulose hydrolysis produces the following disaccharide:

Cellobiose

Glucose

Sucrose

Maltose

Lactose

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Transformation C2H4 (alkene) −→ C2H6 (alkane) occurs during the following reaction:

Hydration

Dimerization

Hydrogenation

Dehydration

Dehydrogenation

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What type of bonds participates in creation of both linear and cyclic carboxylic acid associates in the form of dimers?

Ionic bonds

Nonpolar covalent bonds

Hydrogen bonds

Polar covalent bonds

Donor-acceptor bonds

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The end-productof heating bromoethane with aqueous solution of potassium hydroxide is:?

Diethyl ether

Ethane

Ethanol

Ethene

Ethanoic acid

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Name the product of starch hydrolysis:

Galactose

Fructose

Glucose

Ribose

Mannose

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What is the formula of salicylic acid?

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Which of the compounds given below is an aromatic one?

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Which of the listed monosaccharides is a ketose?

Galactose

Ribose

Glucose

Mannose

Fructose

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Fructose is a monosaccharide, glucose isomer. In medicine it is used in treatment of hepatic disorders and as a part of special diets. Which formula corresponds with Dfructose?

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Dibazol (Bendazol) is a hypotensive antispasmodic drug. Its mechanism of action is based on its ability to block phosphodiesterase type 4 enzyme activity. This drug contains the following heterocyclic compound:

Thiazole

Pyrimidine

Benzimidazole

Pyridine

Benzene

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Which formula corresponds with β-D-glucopyranose?

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What compound is synthesized by means of beta-picoline oxidation?

Nicotinic acid

Ascorbic acid

Uric acid

Benzoic acid

Barbituric acid

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What compound will be produced as the result of toluene chlorination in the presence of FeCl3 catalyst?

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What value determines the degree of influence that foreign ions have on the potential of an ion-selective electrode?

Diffusion coefficient

Selectivity coefficient

Osmotic coefficient

Activity coefficient

Electrical conductivity coefficient

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Name the process of spontaneous adhesion of drops in an emulsion to each other:

Coagulation

Flotation

Flocculation

Sedimentation

Coalescence

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Enzymes are widely used as drugs in pharmacy. What is the main difference that separates enzymes from non-biological catalysts?

High universality

High homogeneity

High specificity and selectivity

High dispersion

Low universality

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Name the structural unit of a colloidal solution of a medicinal substance:

Molecule

Ion

Micelle

Zwitterion

Atom

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Surfactants and high-molecular compounds are added into concentrated emulsions to stabilize them. These substances are:

Catalysts

Emulsifiers

Solvents

Absorbents

Activators

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Specify the order of acetone breakdown reaction: CH3COCH3 = C2H4 + H2 + CO

Zero

First

Fractional

Second

Third

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What two methods of obtaining a disperse system can be characterized as physical condensation?

Vapour condensation and solvent substitution

Ultrafiltration and vapour condensation

Ultrafiltration and peptization

Dispergation and peptization

Chemical condensation and peptization

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If in the process of molecular adsorption the solute is being adsorbed more than the solvent, then the following occurs:

Ion adsorption

Positive adsorption

Negative adsorption

No adsorption

Selective adsorption

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What device is used to measure surface tension of a liquid?

Nephelometer

Calorimeter

Areometer

Stalagmometer

Viscometer

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Sedimentation is characteristic of the following systems:

Electrolyte solutions

Suspensions

Solutions of high-molecular compounds

Nonelectrolyte solutions

Foams

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Under certain conditions, solutions of high-molecular substances can lose their flowability, meaning that the bonds begin to form between macromolecules, leading to the formation of a spatial grid. Name this process:

Peptization

Coagulation

Gel formation

Condensation

Coacervation

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Collagen, gelatin, keratin, and myosin are the proteins that are formed with peptide bonds and resemble long threads in shape. Name this type of proteins:

Fibrillar proteins

Globular proteins

-

Chain proteins

Structured proteins

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Name the ability of high-molecular compounds to prevent precipitation of lyophobic sols and deposition of cholesterol plaques on the vessel walls:

Coacervation

Sedimentation

Colloid protection

Thixotropy

Coagulation

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Saline solution with 0.9% of NaCl in relation to blood serum can be characterized as:

Hypotonic

Isotonic

-

Colloidal

Hypertonic

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Helmholtz energy is a direction criterion of a spontaneous process at a constant:

Entropy and pressure

Temperature and volume

Temperature and pressure

Entropy and volume

Internal energy and volume

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Name the process of removing one or several substances from a complex system by means of a selective solvent:

Evaporation

Dispersion

Condensation

Crystallization

Extraction

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In medical and pharmaceutical practice the phenomena of adsorption, wetting, and adhesion are regularly observed. Name this group of phenomena:

Optical phenomena

Electrokinetic phenomena

Molecular-kinetic phenomena

Surface phenomena

Physico-chemical phenomena

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I.I.Mechnikov, when studying inflammatory process, described a certain order that is characteristic of leukocyte migration to the inflammation focus. The cells emigrate to the focus in the following order:

Lymphocytes, monocytes, neutrophilic granulocytes

Monocytes, lymphocytes, neutrophilic granulocytes

Monocytes, neutrophilic granulocytes, lymphocytes

Neutrophilic granulocytes, lymphocytes, monocytes

Neutrophilic granulocytes, monocytes, lymphocytes

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A patient has developed anuria. Blood pressure is 50/20 mm Hg. What process of uropoiesis caused acute decrease of urination?

Glomerular filtration

Obligatory reabsorption

-

Tubular secretion

Facultative reabsorption

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During lancing an abscess in the oral cavity, it produces a yellow-green discharge. What cells are always present and predominant in the purulent exudate?

Neutrophils

Basophils

Lymphocytes

Eosinophils

Erythrocytes

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People, who were in the building during a fire, suffer from carbon monoxide poisoning. What type of hypoxia can be observed in this case?

Respiratory

Tissue

Circulatory

Hypoxic

Hemic

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A 42-year-old patient presents with skin pallor, weakness, and enlarged lymph nodes. In peripheral blood: leukocytosis, no intermediate forms of leukocytes (”leukemic hiatus”), accelerated ESR. What disease can be suspected in this case?

Leukemoid reaction

Erythromyelosis

Acute leukemia

Neutrophilic leukocytosis

Chronic leukemia

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To reproduce Ehrlich carcinoma in a rabbit, a certain amount of benzpyrene (a polycyclic aromatic hydrocarbon) was daily applied to a dehaired patch of skin of the animal. What method is used for tumor modelling in this case?

Transplantation

Ionizing radiation

Induction

Explantation

Hormone administration

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After a surgery the patient presented with a severe pain syndrome. What change in the patient’s hormonal status is most likely in this case?

Decreased production of mineralocorticoids

Decreased ACTH production

Increased catecholamine production

Decreased production of glucocorticoids

Insulin hypersecretion

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A 9-year-old child due to acute bronchitis developed elevated body temperature up to 38.5oC that lasted for a week and was then followed by a drop in the temperature down to 37.0oC. What mechanism is leading at the 3rd stage of fever?

Increased diuresis

Peripheral vasodilation

Increased heat production

Development of chills

Increased respiration rate

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One hour after a child took polyvitamins in the dosage form of a syrup, the child developed a markedly itching urticaria-type rash all over the body. What type of allergic response can be characterized by this sign?

Anaphylactic

Immune complex

Cytotoxic

Delayed-type hypersensitivity

Autoallergic

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A patient develops prolonged hemorrhages and hemorrhages into the muscles and joints as a result of any microtraumas. In the blood there is a deficiency of the VIII plasma factor of blood coagulation. What disease of blood system is observed in this patient?

B12 and folate deficiency anemia

Iron-deficiency anemia

Hemophilia A

Thrombocytopenic purpura

Vaquez disease (polycythemia vera)

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A man received a radiation dose of 30 Gy. He presents with necrotic angina, disorders of the gastrointestinal tract. Blood tests revealed anemia, leukopenia and thrombocytopenia. What stage of acute radiation sickness is observed in the patient?

Latent stage

Prodromal stage

Manifest illness stage

-

Recovery

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A 54-year-old man requested a pharmacist’s advice on drug prescription. The patient has 4-year-long history of chronic glomerulonephritis and 2-year-long history of persistent hypertension. What substance synthesized in the kidneys has important role in development of arterial hypertension?

Catecholamines

Renin

Nitric oxide

Histamine

Aldosterone

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Examination of a 45-year-old man, who for a long time kept to a vegetarian plantbased diet, revealed him to have negative nitrogen balance. What peculiarity of his diet has caused such developments?

Insufficient protein content

Excessive water content

Insufficient vitamin content

Excessive carbohydrate content

Insufficient fat content

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A 23-year-old man came to the infectious diseases department with complaints of abdominal distension and diarrhea. He was diagnosed with lambliasis. What type of leukocytosis is characteristic of this disease?

Neutrophilic

Basophilic

Eosinophilic

Monocytic

Lymphocytic

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What is the mechanism of indirect action of ionizing radiation on cells?

Activation of protein biosynthesis

Swelling of organelles

Formation of large amount of free radicals

Chromosome rupture

Damage to the cytoplasmic membrane

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A couple came to the genetic consultation for their newborn child to be examined. Karyotype test detects an additional chromosome in the 21 pair. What diagnosis can be made?

Patau syndrome

Edwards syndrome

Turner syndrome

Down syndrome

Klinefelter syndrome

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After a physical exertion a person develops extra (premature) cardiac contractions. What type of arrhythmia is it?

Extrasystole

Sinus bradycardia

Ventricular fibrillation

Sinus tachycardia

Paroxysmal tachycardia

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A 55-year-old man came to a doctor with complaints of acute pain in his big toes. Meat and wine are always present in his diet. The doctor suspects gout. What substance must be measured in the patient’s blood to confirm this diagnosis?

Ketone bodies

Urea

Lactate

Uric acid

Bilirubin

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suffers from diarrhea, dermatitis, and dementia. What vitamin is likely to be deficient in this patient, causing the patient’s condition?

Vitamin K

Retinol

Tocopherol

Nicotinic acid

Vitamin D

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An unconscious patient was brought into the intensive care unit. Acetone breath, acute hyperglycemia, and ketonemia are detected. What complication of diabetes mellitus occurred in this case?

Diabetic coma

Cataract

Nephritis

Hypoglycemic coma

Acute acetone poisoning

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Serum total protein is one of metabolic indicators. What reaction is usually used in clinical laboratories to measure this value?

Fohl

Nitroprusside

Ninhydrin

Xanthoproteic

Biuret

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Thyroid gland produces a hormone that regulates Ca2+ levels in blood, which facilitates mineralization of bone tissue. What hormone has such an effect?

Thyrocalcitonin

Adrenaline

Thyroxin

Triiodothyronine

Dopamine

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A patient is diagnosed with acute pancreatitis. For diagnostic purpose it is necessary to measure the activity of the following enzyme in the patient’s blood:

Creatine kinase

Aldolase

Amylase

LDH

Pepsin

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What enzyme allows for synthesis of various genes from template-RNA to DNA in genetic engineering (this enzyme catalyzes the process discovered in RNAviruses)?

Helicase

DNA-ligase

Endonuclease

Reverse transcriptase

Exonuclease

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Primary structure of nucleic acids is a polynucleotide chain that has a certain composition and order of the nucleotides. What bonds stabilize this structure?

Disulfide

Amide

Glycosidic

Peptide

-phosphodiester

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Gout develops when purine nucleotide metabolism is disturbed. A doctor prescribed the patient allopurinol that is a competitive inhibitor of:

Alcohol dehydrogenase

Lactate dehydrogenase

Hexokinase

Succinate dehydrogenase

Xanthine oxidase

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Cocarboxylase is used in medicine as a pharmaceutical preparation for treatment of myocardial dystrophy and conditions that affect muscles and peripheral CNS. What vitamin is a component of this preparation?

B6

B1

B12

C

B2

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A patient complains of polyuria. Urine test detects no pathologic components, but urine specific gravity is abnormally low. What hormone secretion is likely to be disturbed in this patient?

Somatotropin

Vasopressin

Cortisol

Thyrotropin

Insulin

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A patient with hyperproduction of thyroid hormones has been prescribed Merkazolilum. This drug inhibits the following enzyme participating in iodothyronine synthesis:

Iodide peroxidase

Reductase

Aminotransferase

Decarboxylase

Aromatase

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Ascorutin vitamin preparation is used for treatment of bleeding gums and punctate hemorrhages. What vitamin does this preparation contain? Бiологiчнахiмiя

A

K

C

D

E

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A man developed high plasma iron levels due to intensified hemolysis of erythrocytes. What plasma protein transports iron?

Interferon

Histone

Albumin

Transferrin

Ceruloplasmin

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In case of hypovitaminosis of a certain vitamin, disturbed proliferation of epithelial and connective tissue can be observed. Patients with this type of hypovitaminosis usually present with impaired vision and spatial orientation. Name this vitamin:

Retinol

Riboflavin

Cholecalciferol

Tocopherol

Pyridoxine

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Antihistamines are used in treatment of allergic responses, because histamine functions as an allergic response mediator. Name the amino acid from which histamine is produced:

Alanine

Glycine

Asparagine

Tyrosine

Histidine

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Cholesterol synthesis inhibitors are used as antiatherosclerotic drugs. Select one such drug from the list:

Chloramphenicol

Lovastatin

Pancreatin

Sulfanilamide

Benzylpenicillin

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Aspartame is used as a sweetener and in treatment of diabetes mellitus. What amino acid does it contain?

Valine

Methionine

Leucine

Glutamic acid

Aspartic acid

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Hemoglobin break-up begins in the cells of reticuloendothelial system. What enzyme catalyzes the reduction reaction of biliverdine into bilirubin?

Xanthine oxidase

Biliverdine reductase

Beta-glucuronidase

Hexokinase

Heme oxygenase

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grow in moderately humid conditions belong to the following ecological group:

Hydrophytes

Xerophytes

Hygrophytes

Mesophytes

Succulents

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Among the trees of Fabaceae family there is an early-flowering melliferous plant with pinnately compound leaves, spine-shaped stipules, and white fragrant flowers arranged in hanging racemes. Name this plant:

Aronia melanocarpa

Armeniaca vulgaris

Quercus robur

Robinia pseudoacacia

Aesculus hippocastanum

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Select a Brassicaceae family plant that contains glycosides similar in action to those obtained from foxglove:

Arctostaphylos uva-ursi

Urtica dioica

Erysimum canescens

Primula officinalis

Polygonum aviculare

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Among harvested plants there was Capsella bursa-pastoris, which can be characterized as follows:

Biennial plant, basal leaves - pinnatilobate, fruit - small round silique

Biennial plant, basal leaves - membranous, fruit - small winged heart-shaped silique

Annual plant, basal leaves - pinnatisected or pinnatipartite, fruit - small triangular heart-shaped silique

Annual plant, basal leaves - compound, fruit - segmented silique

Perennial plant, basal leaves - entire-kind, fruit - cylindric silique

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Berberis vulgaris has spines that are modifications of:

Stipules

Rachises

Stems

Leaves

Petioles

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In monocotyledonous plants metabolism end-products are often represented by multiple needle crystals of calcium oxalate arranged in clusters. Name these structures:

Druses

Twinned crystals

Crystalline sand

Raphides

Styloids

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Name the male gametophyte of flowering plants:

Pollen grains

Ovule

Carpel

Nucellus

Embryo sac

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A gastric tea contains small oval brown lignified cone-shaped plant parts up to 1.5 cm in length that can be identified as:

Larch cones

Aggregate fruits of alnus

Platycladus orientalis cones

Berry-like juniper cones

Cypress cones

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A diagnostic feature important for correct identification of pine species is the number of needles on the short shoots (brachyblasts). Pinus sylvestris has the following number of needles on its short shoots:

3

8

2

5

Many

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In pharmaceutical manufacturing, rutin and quercetin are obtained from the flowers of a certain Fabaceae family plant. Name this plant:

Styphnolobium japonicum

Robinia pseudoacacia

Astragalus piletocladus

Acacia dealbata

Caragana arborescens

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A cough tea contains comminuted roots of a plant. The roots are colored bright yellow and taste sweet. They were identified as roots of the following plant:

Glycyrrhiza glabra

Valeriana officinalis

Sanguisorba officinalis

Althaea officinalis

Acorus calamus

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Nuciform fruits include a certain type of one-seeded fruit that does not burst when ripe. Its base is enclosed in a cup-shaped cupule formed by the broad part of the peduncle to which the flower was attached. Name this type of fruit:

Samara

Nutlet

Nut

Caryopsis

Acorn

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Plantago major inflorescence grows at the apex, its rachis is long, with sessile flowers. Name this type of inflorescence:

Spadix

Thyrse

Capitulum

Panicle

Spike

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Upon examination of a flower it is determined to have one pistil made up of single free carpel. Therefore, this gynoecium can be identified as:

Apocarpous

Monocarpous

Paracarpous

Syncarpous

Lysicarpous

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One of the important diagnostic features of garden sage and motherwort is their shape of corolla. Their flowers have the following type of corolla:

Thimble-shaped

Funnelform

Pseudoligulate

Bilabiate

Ligulate

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Rhizome of an Asteraceae family species is polycephalous, succulent, has lysigenous cavities, accumulates inulin. Such underground organ is characterisic of:

Inula helenium

Sorbus aucuparia

Digitalis grandiflora

Hyoscyamus niger

Helianthus annuus

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To obtain bacterial exotoxins, microorganisms are cultivated in a liquid nutrient medum, into which the toxins are being discharged. What method allows clearing the medium of microorganisms, so that only pure exotoxins will remain in the medium?

Ultraviolet irradiation

Application of disinfectants (Chloramine)

Filtration through bacterial filters

Boiling

Autoclaving

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In the course of bacteriological examination of the feces of a patient with diarrhea, a pure culture of slightly curved bacilli was obtained. In the microslide these microorganisms were arranged in clusters resembling schools of fish. Cultivation in the alkaline medium (alkaline peptone water) in six hours resulted in formation of a bluetinged film. These features are characteristic of the following causative agent:

Colibacilli

Vibrio cholerae

Spirochetes

Mycobacteria

Salmonellae

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One day after eating meatballs in the school canteen, several students came to the nurse’s office complaining of stomachache, vomiting, high body temperature, and diarrhea. One of the students was hospitalized in a severe condition. What microorganisms can be the cause of this food toxicoinfection?

Clostridiae

Shigellae

Meningococci

Streptococci

Salmonellae

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For tetanus prevention a certain toxin is used. For 4 weeks this toxin is being neutralized with formaldehyde (0.4%) under the temperature of 39oC. Name the resulting preparation:

Immunoglobulin

Anatoxin

Antitoxic serum

Inactivated vaccine

Adjuvant

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After examination the patient was diagnosed with tick-borne encephalitis. What route of transmission is characteristic of this disease?

Parenteral transmission

Airborne droplet transmission

Vector-borne transmission

Fecal-oral transmission

Vertical transmission

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A chemotherapeutic agent has bactericidal effect against streptococci, staphylococci, bacilli, and clostridia. According to its action spectrum this drug belongs to the following group:

Narrow spectrum antibacterial agents

Broad spectrum antibacterial agents

Antituberculous agents

Broad spectrum antifungal agents

Antiviral agents

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It is known, that HIV infection leads to severe immunologic disturbances in the body that result in the development of AIDS (acquired immune deficiency syndrome). What cells of the human body are the most susceptible to HIV infection?

Hepatocytes

Suppressor T cells

T helper cells

B lymphocytes

Endotheliocytes

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Microbe survival within environment is facilitated by spore formation. What genus of microorganisms can be characterized as spore formers:

Staphylococcus

Clostridium

Peptostreptococcus

Bacteroides

Peptococcus

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To induce an artificially acquired active immunity, a three-month-oldchild was given orally a Sabin strain-based live cultural vaccine. This vaccine is used for prevention of:

Poliomyelitis

Parotitis

Measles

Tuberculosis

Rubella

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After examination the child was diagnosed with scarlet fever. What microorganism is a causative agent of this disease?

Staphylococcus

Klebsiella

Streptococcus

Actinomycete

Meningococcus

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A ready-made drug was inoculated on Sabouraud’s agar and incubated under 22oC for 5 days. This nutrient medium was used to determine the following:

Presence of Salmonella

Number of mold and yeast fungi

Presence of S. aureus

Presence of E. coli

Total number of bacteria

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Seitz filters are widely used in laboratory practice. What is their purpose?

Disinfection of solutions

Virus destruction

Measurement of water contamination

Sterilization by means of filtration

Growing of bacteriophages

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Thermolabile medicinal preparation for extemporal use was heated to 65oC thrice with intervals of one day between the heatings. What method of sterilization was used in this case?

Filtration

Calcination

Tyndallization

Pasteurization

Koch’s steam sterilization

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Many serological reactions require strictly aseptic conditions. What method of sterilization is optimal for decontamination of laboratory glassware?

Dry heat

Tyndallization

Calcination

Pasteurization

Filtration

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During microscopy of a smear made from the sputum sample and stained according to the Ziehl-Neelsen technique, the medical laboratory scientist detected bright red acid-fast bacilli arranged separately and in groups. What microorganisms were detected?

Staphylococcus aureus

Salmonella typhi

Bordetella pertussis

Bacillus anthracis

Micobacterium tuberculosis

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Sanitary-microbiological assessment of water quality in the water supply system conducted by the sanitary-epidemiological station detected microorganisms indicative of fecal contamination of water. What microorganisms were detected?

Escherichia coli

Staphylococcus aureus

Streptococcus agalactiae

Neisseria sicca

Haemophilus influenzae

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Air contamination with pathological microorganisms can be anticipated by the presence of indicator bacteria. Specify the bacteria that indicate immediate epidemiologic danger:

Sarcinae

Yeast fungi

Hemolytic streptococci

Mold fungi

Micrococci

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It can be safely assumed that the infants born from the mothers with the history of measles will not be affected by the measles outbreak during their stay in the maternity ward. What classes of antibodies provide the infants with the resistance to this disease?

IgM

IgD

IgA

IgE

IgG

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During a surgery, tubocurarin chloride was used as a muscle relaxant. What antagonist should the patient be given to restore spontaneous breathing?

Aethimizole (Methylamide)

Proserin (Neostigmine)

Dithylin (Suxamethonium)

Benzohexonium (Hexamethonium)

Cytitone (Cytisine)

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A patient, who has been taking phenazepam for a month, came to the pharmacy. He insists that he needs to buy two more packages of this drug, because without it he feels unwell. The side-effect of this drug that can be observed in this patient is based on the development of:

Cumulation

After-effect

Idiosyncrasy

Tolerance

Addiction

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Select the halogenated antiseptic that would be preferable for a child to pack in the first aid kit, when going to a summer camp:

Formaldehyde solution

Brilliant green

Copper sulfate

Iodine alcoholic solution

Methylene blue

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A medical student needs to choose an adrenergic drug for treatment of anaphylactic shock. What would you recommend?

Clophelin (Clonidine)

Galazolin (Xylometazoline)

Adrenaline hydrochloride

Izadrin (Isoprenaline)

Fenoterol

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What is the main mechanism of benzylpenicillin bactericidal action on the coccal flora?

Inhibition of protein synthesis

Increased phagocytic activity of leukocytes

Disturbed cytoplasmic membrane permeability

Activation of macroorganism immune system

Disturbed synthesis of microbial cell wall

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What drug can quickly stop an angina pectoris attack, when taken sublingually?

Lisinopril

Nitroglycerine

Digoxin

Amiodarone

Corglycon

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Name the ability of a drug to accumulate within the patient’s body:

Cumulation

Habituation

Allergy

Synergism

Antagonism

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You work in the pharmacy located at the premises of the dermatovenerologic clinic. Consult an intern what antibiotic is a drug of choice for treatment of syphilis:

Streptomycin sulfate

Benzylpenicillin sodium salt

Levorin sodium salt

Polymyxin M sulfate

Lincomycin hydrochloride

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A doctor has prescribed a nonsteroidal anti-inflammatory drug to relieve inflammation and pain syndrome. Name this drug:

Loratadine

Calcium chloride

Prednisolone

Glibenclamide

Diclofenac sodium

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What is the most common side-effect of inhaled corticosteroids?

Subcapsular cataract

Oropharyngeal candidiasis

Arterial hypertension

Increased body mass

Osteoporosis

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Treatment with sodium bromide resulted in development of bromism in the patient: rhinitis, cough, conjunctivitis, and skin rashes. What should the patient be prescribed to treat this condition?

Sodium iodide

Potassium chloride

Sodium sulfate

Calcium chloride

Sodium chloride

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A patient with allergic rhinitis was prescribed loratadine. This drug belongs to the following group of antiallergic agents:

H1-antagonists

Membrane stabilizers

Glucocorticoids

Leukotriene receptor antagonists

H2-antagonists

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A patient suffers from intense cough with production of viscous sputum. What drug can thin the sputum and facilitate expectoration?

Acetylcysteine

Butamirate

Prenoxdiazine

Codeine phosphate

Glaucine

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A patient with myocardial infarction was receiving heparin as a part of the complex therapy. With time the patient developed hematuria. What drug should be given as an antidote in this case?

Neodicumarin

Aminocaproic acid

Protamine sulfate

Vicasol (Menadione)

Fibrinogen

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A patient with tracheitis was prescribed a centrally acting antitussive drug that does not depress respiration, causes no addiction, and lowers blood pressure. Name this drug:

Prenoxdiazine

Acetylcysteine

Glaucine hydrochloride

Codeine phosphate

Morphine hydrochloride

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What drug is used for treatment of organophosphate poisoning?

Atropine sulfate

Izoniazid

Platyphylline

Metronidazole

Aciclovir

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Select the drug with anti-herpesvirus activity that can be used for prevention and treatment of herpetic lesions on skin and mucosa:

Aciclovir

Rifampicin

Nystatin

Ranitidine

Atropine

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Forced diuresis needs to be induced in a patient with acute medication poisoning. What drug must be used for this purpose?

Bisacodil

Diphenhydramine

Progesterone

Furosemide

Strophantin

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Caffeine is one of the alkaloids contained in tea and coffee. Caffeine is contraindicated in case of:

Fatigue

Depression of nervous activity

Essential hypertension

Hypotension

Migraine

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To quickly relieve the state of acute psychosis, the patient was prescribed a rapid/short-acting psychotropic drug. Name this drug:

Amitriptyline

Valerian extract

Caffeine and sodium benzoate

Droperidol

Piracetam

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After ishemic stroke the patient was prescribed a drug to improve his intellectual functioning and memory. What drug should he obtain from the pharmacy?

Diphenin (Phenytoin)

Metoclopramide

Tabex (Cytisine)

Piracetam

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