Step 1 - Pharmacy 2020

What titrimetric method of analysis requires the use of both external and internal indicators?

Alkalimetry

Nitritometry

Permanganatometry

Complexometric titration

Argentometry

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A solution contains calcium, barium, aluminium, potassium, and sodium cations. Into this solution a small amount of ammonium hydroxide and alizarin solution was added, which resulted in production of red precipitate. What ion was detected as the result of this reaction?

Calcium

Potassium

Sodium

Barium

Aluminium

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Select an indicator for argentometric determination of chloride ions using the Mohr method:

Methyl red

Diphenylcarbazone

Fluorescein

Potassium chromate

Eosin

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Quantitative determination of copper salts by means of photometric titration should be conducted according to the calibration graph that is built within the following coordinates:

Optical density - wavelength

Optical density - temperature

Optical density - concentration

Light absorption intensity - wavelength

Optical density - liquid layer thickness

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2M solution of HCl was added into the solution being studied, which resulted in formation of white precipitate that turned black when processed with ammonia solution. What cation is present in this solution?

Hg2+

Ag+

Ba2+

Pb2+

Mg2+

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What should be measured during quantitative determination of glucose by means of polarimetry?

Light beam dispersion in the solution

Refractive index

Rotation angle of a polarized light beam

Optical density of the solution

Absorption coefficient of a polarized light beam in the solution

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Concentration of ethyl alcohol in tinctures and some other dosage forms can be determined by means of refractometry. For this purpose the following should be measured:

Angle of total internal reflection of a light beam

Rotation angle of a light polarization plane

Light beam incidence angle

Solution refractive index

Light beam refraction angle

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Ammonium thiocyanate solution was added into the solution being studied. The resulting solution colored red. This analytical effect indicates the presence of the following cation:

Mercury(II)

Lead(II)

Silver

Mercury(I)

Iron(III)

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What reference electrode should be used for potentiometric determination in a solution that contains ammonia and sodium hydroxide?

Silver chloride

Glass

Platinum

Zinc

Silver

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When barium chloride solution was added into the solution being studied, it resulted in a white precipitate that was acidand alkali-insoluble, which indicates that this solution contains:

Sulfate ions

Iron(II) ions

Chloride ions

Permanganate ions

Nitrate ions

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What laboratory glassware is used in titrimetric methods of analysis to measure out a precise volume of a titrant?

Pipette

Measuring glass

Measuring cylinder

Burette

Volumetric flask

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Quantitative content of oxalic acid can be determined by means of permanganatometry. How to determine the equivalence point for this kind of titration?

With adsorption indicator

With specific indicator

When titrate changes its color after another drop of working solution is added

With redox indicator diphenylamine

With pH indicator

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Specify what method of redox titration requires the use of specific indicator - starch - to fix the end point:

Bromatometry

Nitritometry

Permanganatometry

Cerimetry

Iodometry

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To separate cations of the 6th analytical group from cations of the 5th analytical group (acid-base classification), the following is used:

Silver nitrate solution

Acetic acid solution

Excess ammonia solution

Excess sodium hydroxide solution

Excess sulfuric acid solution

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To determine mass-volume fraction of ammonia in a solution, the following solution should be used:

Hydrochloric acid

Iodine

Sodium hydroxide

Sulfuric acid

Potassium permanganate

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Pharmacopoeia reaction to determine benzoate ions requires interaction with the solution of:

Acetic anhydride

Resorcin

Potassium chloride

Iron(III) chloride

Diphenylamine

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What reference electrode can be used in potentiometric analysis of a medicinal substance?

Glass

Antimony

Zinc

Silver chloride

Quinhydrone

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Why is there no group reagent for the cations of the 1st analytical group (acid-base cassification)?

They belong to biologically important elements

They have close ionic radii

They have large ionic radii

Most of their salts are water-soluble

They can form soluble bases

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What working solutions (titrants) are used in Volhard method (precipitation titration)?

AgNO3 and NH4SCN

Na2S2O3 and K[I3]

KMnO4 and KBrO3

H2SO4 and NaOH

HClO4 and KOH

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The third analitycal group of cations (acid-base classification) includes Ca2+, Sr2+, Ba2+. What acid can function as a precipitator agent (group reagent) for these cations?

CH3COOH

H2SO4

HCIO4

HCI

HNO3

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Reaction of sodium ions with potassium hexahydroxoantimonate(V) in neutral medium produces precipitate. Specify the color of this precipitate:

Yellow

Green

Blue

White

Red

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Which compound of those listed below is a condensed arene?

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Specify the Wurtz reaction among those given below:

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Select the formula of diazonium salt:

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Salts and esters of oxalic acid are called:

Malonates

Urates

Adipates

Succinates

Oxalates

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What test is used for identification of uric acid and other compounds with purine nucleus?

Copper mirror reaction

Fehling reagent

Murexide reaction

Silver mirror reaction

Lucas reagent

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Select the compound with both pyrrole and pyridine nitrogen atoms from those given below:

Pyrimidine

2-Aminopyridine

Pteridine

Pyridazine

Theophylline

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What reagent allows distinguishing between maltose (a reducing disaccharide) and sucrose (a non-reducing disaccharide)?

Br2

Tollens reagent

FeCl3

K4[Fe(CN6)]

NaOH

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Specify the name of the alkene given below according to the IUPAC substitutive nomenclature:

2-Ethyl-4-methyl-3-pentene

4-Ethyl-2-methyl-2-pentene

4-Ethyl-2-methyl-3-pentene

3,5-Dimethyl-4-hexene

2,4-Dimethyl-2-hexene

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Cellulose hydrolysis produces the following disaccharide:

Cellobiose

Glucose

Sucrose

Lactose

Maltose

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Transformation C2H4 (alkene) −→ C2H6 (alkane) occurs during the following reaction:

Hydration

Hydrogenation

Dehydration

Dehydrogenation

Dimerization

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What type of bonds participates in creation of both linear and cyclic carboxylic acid associates in the form of dimers?

Donor-acceptor bonds

Polar covalent bonds

Ionic bonds

Hydrogen bonds

Nonpolar covalent bonds

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The end-productof heating bromoethane with aqueous solution of potassium hydroxide is:?

Ethene

Ethanoic acid

Ethane

Ethanol

Diethyl ether

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Name the product of starch hydrolysis:

Glucose

Fructose

Mannose

Galactose

Ribose

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What is the formula of salicylic acid?

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Which of the compounds given below is an aromatic one?

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Which of the listed monosaccharides is a ketose?

Galactose

Ribose

Glucose

Mannose

Fructose

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Fructose is a monosaccharide, glucose isomer. In medicine it is used in treatment of hepatic disorders and as a part of special diets. Which formula corresponds with Dfructose?

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Dibazol (Bendazol) is a hypotensive antispasmodic drug. Its mechanism of action is based on its ability to block phosphodiesterase type 4 enzyme activity. This drug contains the following heterocyclic compound:

Pyrimidine

Pyridine

Benzimidazole

Thiazole

Benzene

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Which formula corresponds with β-D-glucopyranose?

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What compound is synthesized by means of beta-picoline oxidation?

Benzoic acid

Uric acid

Barbituric acid

Nicotinic acid

Ascorbic acid

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What compound will be produced as the result of toluene chlorination in the presence of FeCl3 catalyst?

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What value determines the degree of influence that foreign ions have on the potential of an ion-selective electrode?

Activity coefficient

Electrical conductivity coefficient

Selectivity coefficient

Osmotic coefficient

Diffusion coefficient

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Name the process of spontaneous adhesion of drops in an emulsion to each other:

Flocculation

Coalescence

Flotation

Sedimentation

Coagulation

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Enzymes are widely used as drugs in pharmacy. What is the main difference that separates enzymes from non-biological catalysts?

Low universality

High homogeneity

High universality

High specificity and selectivity

High dispersion

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Name the structural unit of a colloidal solution of a medicinal substance:

Molecule

Micelle

Zwitterion

Atom

Ion

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Surfactants and high-molecular compounds are added into concentrated emulsions to stabilize them. These substances are:

Solvents

Absorbents

Emulsifiers

Activators

Catalysts

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Specify the order of acetone breakdown reaction: CH3COCH3 = C2H4 + H2 + CO

Fractional

First

Third

Second

Zero

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What two methods of obtaining a disperse system can be characterized as physical condensation?

Ultrafiltration and peptization

Vapour condensation and solvent substitution

Chemical condensation and peptization

Dispergation and peptization

Ultrafiltration and vapour condensation

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If in the process of molecular adsorption the solute is being adsorbed more than the solvent, then the following occurs:

Negative adsorption

Positive adsorption

No adsorption

Selective adsorption

Ion adsorption

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What device is used to measure surface tension of a liquid?

Stalagmometer

Viscometer

Calorimeter

Nephelometer

Areometer

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Sedimentation is characteristic of the following systems:

Suspensions

Solutions of high-molecular compounds

Electrolyte solutions

Nonelectrolyte solutions

Foams

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Under certain conditions, solutions of high-molecular substances can lose their flowability, meaning that the bonds begin to form between macromolecules, leading to the formation of a spatial grid. Name this process:

Coagulation

Condensation

Coacervation

Peptization

Gel formation

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Collagen, gelatin, keratin, and myosin are the proteins that are formed with peptide bonds and resemble long threads in shape. Name this type of proteins:

Globular proteins

Chain proteins

Structured proteins

Fibrillar proteins

-

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Name the ability of high-molecular compounds to prevent precipitation of lyophobic sols and deposition of cholesterol plaques on the vessel walls:

Coacervation

Coagulation

Sedimentation

Thixotropy

Colloid protection

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Saline solution with 0.9% of NaCl in relation to blood serum can be characterized as:

Colloidal

Hypotonic

-

Isotonic

Hypertonic

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Helmholtz energy is a direction criterion of a spontaneous process at a constant:

Internal energy and volume

Temperature and volume

Temperature and pressure

Entropy and pressure

Entropy and volume

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Name the process of removing one or several substances from a complex system by means of a selective solvent:

Crystallization

Dispersion

Evaporation

Extraction

Condensation

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In medical and pharmaceutical practice the phenomena of adsorption, wetting, and adhesion are regularly observed. Name this group of phenomena:

Electrokinetic phenomena

Optical phenomena

Surface phenomena

Molecular-kinetic phenomena

Physico-chemical phenomena

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I.I.Mechnikov, when studying inflammatory process, described a certain order that is characteristic of leukocyte migration to the inflammation focus. The cells emigrate to the focus in the following order:

Neutrophilic granulocytes, monocytes, lymphocytes

Monocytes, lymphocytes, neutrophilic granulocytes

Lymphocytes, monocytes, neutrophilic granulocytes

Monocytes, neutrophilic granulocytes, lymphocytes

Neutrophilic granulocytes, lymphocytes, monocytes

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A patient has developed anuria. Blood pressure is 50/20 mm Hg. What process of uropoiesis caused acute decrease of urination?

Tubular secretion

-

Glomerular filtration

Facultative reabsorption

Obligatory reabsorption

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During lancing an abscess in the oral cavity, it produces a yellow-green discharge. What cells are always present and predominant in the purulent exudate?

Basophils

Eosinophils

Neutrophils

Lymphocytes

Erythrocytes

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People, who were in the building during a fire, suffer from carbon monoxide poisoning. What type of hypoxia can be observed in this case?

Tissue

Hemic

Hypoxic

Circulatory

Respiratory

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A 42-year-old patient presents with skin pallor, weakness, and enlarged lymph nodes. In peripheral blood: leukocytosis, no intermediate forms of leukocytes (”leukemic hiatus”), accelerated ESR. What disease can be suspected in this case?

Leukemoid reaction

Neutrophilic leukocytosis

Erythromyelosis

Chronic leukemia

Acute leukemia

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To reproduce Ehrlich carcinoma in a rabbit, a certain amount of benzpyrene (a polycyclic aromatic hydrocarbon) was daily applied to a dehaired patch of skin of the animal. What method is used for tumor modelling in this case?

Explantation

Induction

Transplantation

Hormone administration

Ionizing radiation

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After a surgery the patient presented with a severe pain syndrome. What change in the patient’s hormonal status is most likely in this case?

Decreased production of glucocorticoids

Insulin hypersecretion

Decreased ACTH production

Increased catecholamine production

Decreased production of mineralocorticoids

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A 9-year-old child due to acute bronchitis developed elevated body temperature up to 38.5oC that lasted for a week and was then followed by a drop in the temperature down to 37.0oC. What mechanism is leading at the 3rd stage of fever?

Increased heat production

Development of chills

Peripheral vasodilation

Increased respiration rate

Increased diuresis

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One hour after a child took polyvitamins in the dosage form of a syrup, the child developed a markedly itching urticaria-type rash all over the body. What type of allergic response can be characterized by this sign?

Cytotoxic

Immune complex

Anaphylactic

Autoallergic

Delayed-type hypersensitivity

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A patient develops prolonged hemorrhages and hemorrhages into the muscles and joints as a result of any microtraumas. In the blood there is a deficiency of the VIII plasma factor of blood coagulation. What disease of blood system is observed in this patient?

B12 and folate deficiency anemia

Thrombocytopenic purpura

Iron-deficiency anemia

Vaquez disease (polycythemia vera)

Hemophilia A

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A man received a radiation dose of 30 Gy. He presents with necrotic angina, disorders of the gastrointestinal tract. Blood tests revealed anemia, leukopenia and thrombocytopenia. What stage of acute radiation sickness is observed in the patient?

-

Latent stage

Recovery

Prodromal stage

Manifest illness stage

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A 54-year-old man requested a pharmacist’s advice on drug prescription. The patient has 4-year-long history of chronic glomerulonephritis and 2-year-long history of persistent hypertension. What substance synthesized in the kidneys has important role in development of arterial hypertension?

Histamine

Renin

Catecholamines

Aldosterone

Nitric oxide

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Examination of a 45-year-old man, who for a long time kept to a vegetarian plantbased diet, revealed him to have negative nitrogen balance. What peculiarity of his diet has caused such developments?

Excessive water content

Insufficient vitamin content

Excessive carbohydrate content

Insufficient protein content

Insufficient fat content

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A 23-year-old man came to the infectious diseases department with complaints of abdominal distension and diarrhea. He was diagnosed with lambliasis. What type of leukocytosis is characteristic of this disease?

Monocytic

Basophilic

Eosinophilic

Lymphocytic

Neutrophilic

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What is the mechanism of indirect action of ionizing radiation on cells?

Formation of large amount of free radicals

Chromosome rupture

Swelling of organelles

Damage to the cytoplasmic membrane

Activation of protein biosynthesis

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A couple came to the genetic consultation for their newborn child to be examined. Karyotype test detects an additional chromosome in the 21 pair. What diagnosis can be made?

Patau syndrome

Klinefelter syndrome

Turner syndrome

Down syndrome

Edwards syndrome

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After a physical exertion a person develops extra (premature) cardiac contractions. What type of arrhythmia is it?

Extrasystole

Paroxysmal tachycardia

Sinus bradycardia

Ventricular fibrillation

Sinus tachycardia

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A 55-year-old man came to a doctor with complaints of acute pain in his big toes. Meat and wine are always present in his diet. The doctor suspects gout. What substance must be measured in the patient’s blood to confirm this diagnosis?

Uric acid

Urea

Lactate

Bilirubin

Ketone bodies

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suffers from diarrhea, dermatitis, and dementia. What vitamin is likely to be deficient in this patient, causing the patient’s condition?

Tocopherol

Retinol

Vitamin K

Vitamin D

Nicotinic acid

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An unconscious patient was brought into the intensive care unit. Acetone breath, acute hyperglycemia, and ketonemia are detected. What complication of diabetes mellitus occurred in this case?

Acute acetone poisoning

Hypoglycemic coma

Nephritis

Diabetic coma

Cataract

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Serum total protein is one of metabolic indicators. What reaction is usually used in clinical laboratories to measure this value?

Xanthoproteic

Fohl

Nitroprusside

Biuret

Ninhydrin

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Thyroid gland produces a hormone that regulates Ca2+ levels in blood, which facilitates mineralization of bone tissue. What hormone has such an effect?

Thyrocalcitonin

Triiodothyronine

Dopamine

Thyroxin

Adrenaline

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A patient is diagnosed with acute pancreatitis. For diagnostic purpose it is necessary to measure the activity of the following enzyme in the patient’s blood:

LDH

Amylase

Pepsin

Aldolase

Creatine kinase

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What enzyme allows for synthesis of various genes from template-RNA to DNA in genetic engineering (this enzyme catalyzes the process discovered in RNAviruses)?

Exonuclease

Reverse transcriptase

Endonuclease

Helicase

DNA-ligase

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Primary structure of nucleic acids is a polynucleotide chain that has a certain composition and order of the nucleotides. What bonds stabilize this structure?

Glycosidic

Amide

-phosphodiester

Disulfide

Peptide

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Gout develops when purine nucleotide metabolism is disturbed. A doctor prescribed the patient allopurinol that is a competitive inhibitor of:

Hexokinase

Succinate dehydrogenase

Alcohol dehydrogenase

Lactate dehydrogenase

Xanthine oxidase

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Cocarboxylase is used in medicine as a pharmaceutical preparation for treatment of myocardial dystrophy and conditions that affect muscles and peripheral CNS. What vitamin is a component of this preparation?

B2

C

B6

B12

B1

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A patient complains of polyuria. Urine test detects no pathologic components, but urine specific gravity is abnormally low. What hormone secretion is likely to be disturbed in this patient?

Cortisol

Somatotropin

Insulin

Vasopressin

Thyrotropin

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A patient with hyperproduction of thyroid hormones has been prescribed Merkazolilum. This drug inhibits the following enzyme participating in iodothyronine synthesis:

Aminotransferase

Iodide peroxidase

Reductase

Decarboxylase

Aromatase

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Ascorutin vitamin preparation is used for treatment of bleeding gums and punctate hemorrhages. What vitamin does this preparation contain? Бiологiчнахiмiя

K

D

A

E

C

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A man developed high plasma iron levels due to intensified hemolysis of erythrocytes. What plasma protein transports iron?

Transferrin

Albumin

Histone

Ceruloplasmin

Interferon

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In case of hypovitaminosis of a certain vitamin, disturbed proliferation of epithelial and connective tissue can be observed. Patients with this type of hypovitaminosis usually present with impaired vision and spatial orientation. Name this vitamin:

Tocopherol

Cholecalciferol

Retinol

Pyridoxine

Riboflavin

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Antihistamines are used in treatment of allergic responses, because histamine functions as an allergic response mediator. Name the amino acid from which histamine is produced:

Glycine

Asparagine

Histidine

Alanine

Tyrosine

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Cholesterol synthesis inhibitors are used as antiatherosclerotic drugs. Select one such drug from the list:

Lovastatin

Pancreatin

Sulfanilamide

Benzylpenicillin

Chloramphenicol

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Aspartame is used as a sweetener and in treatment of diabetes mellitus. What amino acid does it contain?

Methionine

Leucine

Glutamic acid

Valine

Aspartic acid

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Hemoglobin break-up begins in the cells of reticuloendothelial system. What enzyme catalyzes the reduction reaction of biliverdine into bilirubin?

Biliverdine reductase

Beta-glucuronidase

Hexokinase

Xanthine oxidase

Heme oxygenase

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grow in moderately humid conditions belong to the following ecological group:

Xerophytes

Hydrophytes

Mesophytes

Hygrophytes

Succulents

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Among the trees of Fabaceae family there is an early-flowering melliferous plant with pinnately compound leaves, spine-shaped stipules, and white fragrant flowers arranged in hanging racemes. Name this plant:

Aronia melanocarpa

Aesculus hippocastanum

Quercus robur

Armeniaca vulgaris

Robinia pseudoacacia

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Select a Brassicaceae family plant that contains glycosides similar in action to those obtained from foxglove:

Polygonum aviculare

Urtica dioica

Primula officinalis

Erysimum canescens

Arctostaphylos uva-ursi

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Among harvested plants there was Capsella bursa-pastoris, which can be characterized as follows:

Annual plant, basal leaves - compound, fruit - segmented silique

Biennial plant, basal leaves - membranous, fruit - small winged heart-shaped silique

Biennial plant, basal leaves - pinnatilobate, fruit - small round silique

Annual plant, basal leaves - pinnatisected or pinnatipartite, fruit - small triangular heart-shaped silique

Perennial plant, basal leaves - entire-kind, fruit - cylindric silique

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Berberis vulgaris has spines that are modifications of:

Petioles

Rachises

Leaves

Stipules

Stems

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In monocotyledonous plants metabolism end-products are often represented by multiple needle crystals of calcium oxalate arranged in clusters. Name these structures:

Raphides

Crystalline sand

Druses

Styloids

Twinned crystals

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Name the male gametophyte of flowering plants:

Embryo sac

Nucellus

Carpel

Ovule

Pollen grains

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A gastric tea contains small oval brown lignified cone-shaped plant parts up to 1.5 cm in length that can be identified as:

Cypress cones

Berry-like juniper cones

Platycladus orientalis cones

Larch cones

Aggregate fruits of alnus

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A diagnostic feature important for correct identification of pine species is the number of needles on the short shoots (brachyblasts). Pinus sylvestris has the following number of needles on its short shoots:

8

Many

5

3

2

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In pharmaceutical manufacturing, rutin and quercetin are obtained from the flowers of a certain Fabaceae family plant. Name this plant:

Caragana arborescens

Astragalus piletocladus

Robinia pseudoacacia

Acacia dealbata

Styphnolobium japonicum

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A cough tea contains comminuted roots of a plant. The roots are colored bright yellow and taste sweet. They were identified as roots of the following plant:

Althaea officinalis

Valeriana officinalis

Glycyrrhiza glabra

Sanguisorba officinalis

Acorus calamus

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Nuciform fruits include a certain type of one-seeded fruit that does not burst when ripe. Its base is enclosed in a cup-shaped cupule formed by the broad part of the peduncle to which the flower was attached. Name this type of fruit:

Nut

Acorn

Nutlet

Caryopsis

Samara

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Plantago major inflorescence grows at the apex, its rachis is long, with sessile flowers. Name this type of inflorescence:

Panicle

Spadix

Capitulum

Thyrse

Spike

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Upon examination of a flower it is determined to have one pistil made up of single free carpel. Therefore, this gynoecium can be identified as:

Lysicarpous

Syncarpous

Monocarpous

Paracarpous

Apocarpous

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One of the important diagnostic features of garden sage and motherwort is their shape of corolla. Their flowers have the following type of corolla:

Ligulate

Bilabiate

Thimble-shaped

Funnelform

Pseudoligulate

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Rhizome of an Asteraceae family species is polycephalous, succulent, has lysigenous cavities, accumulates inulin. Such underground organ is characterisic of:

Helianthus annuus

Inula helenium

Digitalis grandiflora

Sorbus aucuparia

Hyoscyamus niger

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To obtain bacterial exotoxins, microorganisms are cultivated in a liquid nutrient medum, into which the toxins are being discharged. What method allows clearing the medium of microorganisms, so that only pure exotoxins will remain in the medium?

Autoclaving

Application of disinfectants (Chloramine)

Boiling

Filtration through bacterial filters

Ultraviolet irradiation

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In the course of bacteriological examination of the feces of a patient with diarrhea, a pure culture of slightly curved bacilli was obtained. In the microslide these microorganisms were arranged in clusters resembling schools of fish. Cultivation in the alkaline medium (alkaline peptone water) in six hours resulted in formation of a bluetinged film. These features are characteristic of the following causative agent:

Spirochetes

Colibacilli

Vibrio cholerae

Salmonellae

Mycobacteria

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One day after eating meatballs in the school canteen, several students came to the nurse’s office complaining of stomachache, vomiting, high body temperature, and diarrhea. One of the students was hospitalized in a severe condition. What microorganisms can be the cause of this food toxicoinfection?

Meningococci

Shigellae

Salmonellae

Streptococci

Clostridiae

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For tetanus prevention a certain toxin is used. For 4 weeks this toxin is being neutralized with formaldehyde (0.4%) under the temperature of 39oC. Name the resulting preparation:

Antitoxic serum

Anatoxin

Adjuvant

Immunoglobulin

Inactivated vaccine

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After examination the patient was diagnosed with tick-borne encephalitis. What route of transmission is characteristic of this disease?

Fecal-oral transmission

Vector-borne transmission

Airborne droplet transmission

Parenteral transmission

Vertical transmission

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A chemotherapeutic agent has bactericidal effect against streptococci, staphylococci, bacilli, and clostridia. According to its action spectrum this drug belongs to the following group:

Broad spectrum antibacterial agents

Antituberculous agents

Antiviral agents

Narrow spectrum antibacterial agents

Broad spectrum antifungal agents

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It is known, that HIV infection leads to severe immunologic disturbances in the body that result in the development of AIDS (acquired immune deficiency syndrome). What cells of the human body are the most susceptible to HIV infection?

Suppressor T cells

Endotheliocytes

T helper cells

B lymphocytes

Hepatocytes

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Microbe survival within environment is facilitated by spore formation. What genus of microorganisms can be characterized as spore formers:

Clostridium

Staphylococcus

Peptococcus

Peptostreptococcus

Bacteroides

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To induce an artificially acquired active immunity, a three-month-oldchild was given orally a Sabin strain-based live cultural vaccine. This vaccine is used for prevention of:

Tuberculosis

Rubella

Parotitis

Poliomyelitis

Measles

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After examination the child was diagnosed with scarlet fever. What microorganism is a causative agent of this disease?

Streptococcus

Staphylococcus

Actinomycete

Meningococcus

Klebsiella

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A ready-made drug was inoculated on Sabouraud’s agar and incubated under 22oC for 5 days. This nutrient medium was used to determine the following:

Presence of E. coli

Presence of S. aureus

Number of mold and yeast fungi

Presence of Salmonella

Total number of bacteria

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Seitz filters are widely used in laboratory practice. What is their purpose?

Growing of bacteriophages

Sterilization by means of filtration

Measurement of water contamination

Disinfection of solutions

Virus destruction

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Thermolabile medicinal preparation for extemporal use was heated to 65oC thrice with intervals of one day between the heatings. What method of sterilization was used in this case?

Tyndallization

Pasteurization

Calcination

Koch’s steam sterilization

Filtration

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Many serological reactions require strictly aseptic conditions. What method of sterilization is optimal for decontamination of laboratory glassware?

Calcination

Filtration

Pasteurization

Dry heat

Tyndallization

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During microscopy of a smear made from the sputum sample and stained according to the Ziehl-Neelsen technique, the medical laboratory scientist detected bright red acid-fast bacilli arranged separately and in groups. What microorganisms were detected?

Staphylococcus aureus

Bordetella pertussis

Salmonella typhi

Micobacterium tuberculosis

Bacillus anthracis

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Sanitary-microbiological assessment of water quality in the water supply system conducted by the sanitary-epidemiological station detected microorganisms indicative of fecal contamination of water. What microorganisms were detected?

Streptococcus agalactiae

Staphylococcus aureus

Haemophilus influenzae

Escherichia coli

Neisseria sicca

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Air contamination with pathological microorganisms can be anticipated by the presence of indicator bacteria. Specify the bacteria that indicate immediate epidemiologic danger:

Sarcinae

Micrococci

Yeast fungi

Mold fungi

Hemolytic streptococci

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It can be safely assumed that the infants born from the mothers with the history of measles will not be affected by the measles outbreak during their stay in the maternity ward. What classes of antibodies provide the infants with the resistance to this disease?

IgE

IgM

IgD

IgG

IgA

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During a surgery, tubocurarin chloride was used as a muscle relaxant. What antagonist should the patient be given to restore spontaneous breathing?

Dithylin (Suxamethonium)

Proserin (Neostigmine)

Benzohexonium (Hexamethonium)

Aethimizole (Methylamide)

Cytitone (Cytisine)

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A patient, who has been taking phenazepam for a month, came to the pharmacy. He insists that he needs to buy two more packages of this drug, because without it he feels unwell. The side-effect of this drug that can be observed in this patient is based on the development of:

Tolerance

Cumulation

After-effect

Idiosyncrasy

Addiction

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Select the halogenated antiseptic that would be preferable for a child to pack in the first aid kit, when going to a summer camp:

Methylene blue

Brilliant green

Copper sulfate

Iodine alcoholic solution

Formaldehyde solution

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A medical student needs to choose an adrenergic drug for treatment of anaphylactic shock. What would you recommend?

Fenoterol

Clophelin (Clonidine)

Galazolin (Xylometazoline)

Adrenaline hydrochloride

Izadrin (Isoprenaline)

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What is the main mechanism of benzylpenicillin bactericidal action on the coccal flora?

Inhibition of protein synthesis

Disturbed cytoplasmic membrane permeability

Increased phagocytic activity of leukocytes

Activation of macroorganism immune system

Disturbed synthesis of microbial cell wall

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What drug can quickly stop an angina pectoris attack, when taken sublingually?

Nitroglycerine

Lisinopril

Amiodarone

Corglycon

Digoxin

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Name the ability of a drug to accumulate within the patient’s body:

Antagonism

Habituation

Cumulation

Allergy

Synergism

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You work in the pharmacy located at the premises of the dermatovenerologic clinic. Consult an intern what antibiotic is a drug of choice for treatment of syphilis:

Benzylpenicillin sodium salt

Lincomycin hydrochloride

Levorin sodium salt

Streptomycin sulfate

Polymyxin M sulfate

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A doctor has prescribed a nonsteroidal anti-inflammatory drug to relieve inflammation and pain syndrome. Name this drug:

Diclofenac sodium

Loratadine

Calcium chloride

Glibenclamide

Prednisolone

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What is the most common side-effect of inhaled corticosteroids?

Osteoporosis

Increased body mass

Arterial hypertension

Subcapsular cataract

Oropharyngeal candidiasis

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Treatment with sodium bromide resulted in development of bromism in the patient: rhinitis, cough, conjunctivitis, and skin rashes. What should the patient be prescribed to treat this condition?

Sodium iodide

Calcium chloride

Sodium sulfate

Sodium chloride

Potassium chloride

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A patient with allergic rhinitis was prescribed loratadine. This drug belongs to the following group of antiallergic agents:

Membrane stabilizers

Glucocorticoids

H2-antagonists

H1-antagonists

Leukotriene receptor antagonists

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A patient suffers from intense cough with production of viscous sputum. What drug can thin the sputum and facilitate expectoration?

Codeine phosphate

Butamirate

Acetylcysteine

Prenoxdiazine

Glaucine

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A patient with myocardial infarction was receiving heparin as a part of the complex therapy. With time the patient developed hematuria. What drug should be given as an antidote in this case?

Neodicumarin

Aminocaproic acid

Protamine sulfate

Vicasol (Menadione)

Fibrinogen

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A patient with tracheitis was prescribed a centrally acting antitussive drug that does not depress respiration, causes no addiction, and lowers blood pressure. Name this drug:

Morphine hydrochloride

Codeine phosphate

Acetylcysteine

Glaucine hydrochloride

Prenoxdiazine

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What drug is used for treatment of organophosphate poisoning?

Aciclovir

Izoniazid

Metronidazole

Platyphylline

Atropine sulfate

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Select the drug with anti-herpesvirus activity that can be used for prevention and treatment of herpetic lesions on skin and mucosa:

Nystatin

Atropine

Aciclovir

Ranitidine

Rifampicin

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Forced diuresis needs to be induced in a patient with acute medication poisoning. What drug must be used for this purpose?

Bisacodil

Diphenhydramine

Progesterone

Strophantin

Furosemide

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Caffeine is one of the alkaloids contained in tea and coffee. Caffeine is contraindicated in case of:

Fatigue

Migraine

Hypotension

Depression of nervous activity

Essential hypertension

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To quickly relieve the state of acute psychosis, the patient was prescribed a rapid/short-acting psychotropic drug. Name this drug:

Valerian extract

Caffeine and sodium benzoate

Droperidol

Amitriptyline

Piracetam

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After ishemic stroke the patient was prescribed a drug to improve his intellectual functioning and memory. What drug should he obtain from the pharmacy?

Piracetam

-

Metoclopramide

Diphenin (Phenytoin)

Tabex (Cytisine)

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