Step 1 - Stomatology 2008

Examination of a man revealed a protozoan disease that affected brain and caused vision loss. Blood analysis revealed unicellular half-moon-shaped organisms with pointed end. The causative agent of this disease is:

Amoeba

Leishmania

Lamblia

Toxoplasma

Trichmonad

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A married couple applied to the genetic consultation in order to consult about their child with multiple abnormalities (microcephaly, idiocy etc). The woman has had an illnesses during her pregnancy but she didn’t take any teratogens or mutagens. The parents’ and the child’s karyotype is normal. Anamnesis study revealed that the family kept a cat. What gravidic disease caused the child’s abnormalities?

Balantidiasis

Leishmaniasis

Dysentery

Trichomoniasis

Toxoplasmosis

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A patient has mental retardation, small height, brachydactyly, mongoloid slant. Analysys of his karyotype revealed trisomy 21. What chromosomal anomaly is it?

Turner’s syndrome

Klinefelter’s syndrome

Trisomy X

Down’s disease

Specific fetopathy

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A female patient has symptoms of inflammation of urogenital tracts. A smear from the vaginal mucous membrane contained big unicellular pyriform organisms with a sharp spike on the back end of their bodies; big nucleus and undulating membrane. What protozoa were revealed in the smear?

Trichomonas buccalis

Trypanosoma gambiense

Lamblia intestinalis

Trichomonas vaginalis

Trichomonas hominis

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Analysis of an electron diffraction pattern of a cell revealed mitochondrion destruction. This might result in abnormal course of the following cell process:

-

Nuclear division

Oxidation of organic substances

Cleavage

Crossingover

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Formation of ribosome subunits in a cell was disturbed in course of an experiment (by means of activated mutagenic factors). This will have an effect on the following metabolic process:

Photosynthesis

Carbohydrate biosynthesis

ATP synthesis

Protein biosynthesis

Biological oxidation

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Among public catering workers examined by doctors of sanitary-and-epidemiologic station often occur asymptomatic parasite carriers. This means that a healthy person carries cysts that infect other people. Such parasitizing is impossible for the following causative agent:

Malarial plasmodium

Intestinal trichomonad

Viscerotropic leishmania

Dysenteric amoeba

Dermatotropic leishmania

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It is known that information about sequence of amino acids in a protein molecule is encoded as a sequence of four types of nucleotides in a DNA molecule, and different amino acids are encoded by different number of triplets - from one to six. Such peculiarity of the genetic code is called:

Universality

Triplety

Specificity

Nonoverlapping

Degeneracy

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A patient suffering from caries of the left inferior premolar has got a swelling on his neck above the hyoid bone. There appeared fever, salivary discharge, contraction of masticatory muscles, difficult mouth opening. The patient was diagnosed with phlegmon of mouth floor. What muscles will be involved in the process?

Thyrohyoid and sternohyoid

Platysma and stylohyoid

Digastric and stylohyoid

Hyoglossal and styloglossal

Mylohyoid and geniohyoid

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Vagosympathetic Vishnevsky’s block involves introduction of novocaine along the posterior edge of sternocleidomastoid muscle above its intersection with exterior jugular vein. The block is performed within the following triangle of neck:

Pirogoff’s

Omoclavicular

Omotrapezoid

Submandibular

Carotid

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During approach to the thyroid gland by means of transverse section suprasternal cellular tissue space should be opened. It will be dangerous to damage the following anatomic formation located within this space:

Internal jugular vein

Subclavicular artery

Venous jugular arch

Lymph nodes

Carotid artery

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A female patient with pyelonephritis was admitted to the urological department. Examination revealed an associated infection accompanied by pyelovenous reflux. This complication was induced by affection of the following structure:

Fornical renal apparatus

Straight tubules

Renal corpuscle

Renal tubules

Excretory renal tracts

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A 27 year old patient consulted a doctor about a solid tumour in front of the antilobium. During removal of this tumour a dental surgeon revealed a vein. What vein is localized in this area?

V retromandibularis

V facialis

V jugularis externa

V jugularis interna

V auricularis posterior

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A 24 year old patient consulted a doctor about pain below his lower jaw on the right. Dental surgeon revealed a concrement in the submandibular gland. During its removal he had to prevent bleeding out of the following artery:

A. alveolaris inferior

A. submentalis

A. labialis inferior

A. lingualis

A. facialis

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Study of a patient’s facial gesture revealed that he couldn’t whistle, round his lips; mouth corners didn’t rise during laughing, oral fissure stretched sidewards (transversal smile). These symptoms indicate the atrophy of the following muscle:

Masticatory muscle

Orbicular muscle of mouth

Risorius muscle

Cervical muscle

Greater zygomatic muscle

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A doctor examined a victim of a road accident and revealed damage of the exterior wall of eye socket. The patient has lost ability to abduct the eyeball on the affected side. What nerve might be damaged in this case?

N. abducens

N. oculomotorius

N. infraorbitalis

N. ophthalmicus

N. trochlearis

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After extraction of the II maxillary molar tooth the patient has got haemorrhage from the alveolar socket. The observed haemorrhage is from the system of the following artery:

Inferior alveolar

Maxillary

Ascending pharyngeal

Mylohyoid

Facial

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A basketball player complains of pain over his heel that is getting stronger during walking. It might be caused by damage of tendon of the following muscle:

m. flexor digitorum longus

m. fibularis longus

m. fibularis brevis

m. triceps surae

m. tibialis posterior

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A student has accidentally hit his elbow against the edge of the table and sensed burning and tingling on the interior surface of his forearm. What nerve was damaged in this case?

N. axillaris

N. ulnaris

N. radialis

N. medianus

N. musculocutaneus

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In process of the secretory cycle secretion granules come and go in the apical part of cytoplasm of pancreas cells. These granules relate to the following structure elements:

Lysosomes

Inclusions

Microfilaments

Granular endoplasmic reticulum

Exocytic vacuoles

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A 35 year old female patient diagnosed with infertility underwent diagnostic biopsy of endometrium. Microscopical examination revealed that its mucous membrane was edematic, uterine glands were convoluted and filled with thick secretion. Such changes of endometrium are caused by excess of the following hormone:

Testosterone

Somatotropin

Estrogen

ACTH

Progesterone

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Influence of unfavourable factors upon the organism causes change of thymus accompanied by mass loss of thymocytes, their displacement to the peripheral organs, proliferation of epithelioreticulocytes. What phenomenon is it?

Thymus atrophy

Accidental thymus involution

Thymus hypotrophy

Thymus dystrophy

Age thymus involution

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Examination of a patient revealed abnormal development of enamel. This is caused by damage of the following structural elements of dental germ:

Internal enamel epithelium of enamel organ

Pulp of enamel organ

External enamel epithelium of enamel organ

Cervix of enamel organ

Intermediate layer of enamel organ

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A histological specimen of an oral cavity organ demonstrates that the organ’s anterior surface is lined with multilayer squamous nonkeratinous epithelium, and its posterior surface - with multiserial ciliated epithelium. What organ is it?

Gingiva

Hard palate

Soft palate

Lip

Cheek

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Examination of uterine cavity revealed an embryonated ovum that wasn’t attached to the endometrium. The embryo is at the following stage of development:

Gastrula

Morula

Blastocyst

Zygote

Neurula

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A mountain climber spent a long time in the mountains. Erythrocyte number has risen from 5,0 • 1012/l up to 6,0 • 1012/l. What factor stimulated erythropoiesis?

Increase of O2 in the arterial blood

Increase of O2 in the venous blood

Decrease of O2 in the arterial blood

Decrease of O2 in the venous blood

Increase of O2 in the cells

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What factor may cause increase of power inputs of human organism by 100%?

Consumption of carbohydrate food

Consumption of fatty food

Drop of external temperature

Consumption of protein food

Rise of external temperature

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A 40 year old European works in a Southeast Asian country. He complains that it is hard to bear high temperature under conditions of high relative humidity. The reason for it is difficult heat emission by way of:

Convection and heat conduction

Heat conduction

Radiation

Convection

Evaporation

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Examination of a patient who has recently had a hepatic disease revealed low concentration of prothrombin in blood. First of all this will cause disturbance of:

Anticoagulative blood properties

Second phase of coagulation haemostasis

First phase of coagulation haemostasis

Fibrinolysis

Vasculothrombocytic haemostasis

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Researchers studied speed of excitement conduction in different areas of an isolated heart. Which area demonstrated the lowest speed?

Purkinje’s fibers

His’ bundle

Atrial myocardium

Ventricular myocardium

Atrioventricular node

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A patient who takes blocker of membrane cytoreceptors of efferent conductor synapses of autonomic nervous system complains about dry mouth. What receptors are blocked?

^-adrenoreceptors

Nicotinic cholinoreceptors

Muscarinic cholinoreceptors

3- adrenoreceptors

H2 -receptors

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A student has dry mouth during an exam. This is caused by realization of the following reflexes:

Unconditioned sympathetic and parasympathetic

Conditioned parasympathetic

Conditioned sympathetic

Unconditioned parasympathetic

Conditioned and unconditioned sympathetic

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A child has abnormal formation of tooth enamel and dentin as a result of low concentration of calcium ions in blood. Such abnormalities might be caused by deficiency of the following hormone:

Triiodothyronine

Somatotropic hormone

Thyrocalcitonin

Parathormone

Thyroxin

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ECG of a patient showed that RR interval equaled 1,5 s, heart rate equaled 40 bpm. What is cardiac pacemaker?

Sinus node

Right branch of His’ bundle

His’ bundle

Left branch of His’ bundle

Atrioventricular node

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A patient has hyperkaliemia and hyponatremia. Such changes might be caused by hyposecretion of the following hormone:

Parathormone

Cortisol

Vasopressin

Natriuretic

Aldosterone

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Tissue is being stimulated by electric cathodic impulse with amplitude of 70% of threshold. What changes of membrane potential will be observed?

Hyperpolarization

Partial depolarization

Action potential

No changes

-

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Analysis of a patient’s saliva revealed high concentration of lactate. This is most probably caused by activation of the following process:

Aerobic glucose breakdown

Glucose-lactate cycle

Glycogen breakdown

Anaerobic glucose breakdown

Carbohydrate hydrolysis

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A patient diagnosed with malignant carcinoid has extremely high concentration of serotonin in blood. This biogenic amine can be formed from the following amino acid:

Leucine

Methionine

Alanine

Threonine

Tryptophan

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As a result of improper feeding an infant got full-blown diarrhea. One of its main consequences is excretion of large amount of sodium bicarbonate. What form of acid-base balance disturbance is it?

Acid-base balance won’t be disturbed

Metabolic alkalosis

Excretory acidosis

Respiratory acidosis

Respiratory alkalosis

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A patient suffering from chronic renal insufficiency has got osteoporosis. Osteoporosis was caused by abnormal synthesis of the following regulator of mineral metabolism in kidneys:

Cortisol hydroxylation

Proline hydroxylation

Glutamate carboxylation

Lysine hydroxylation

1, 25(OH)2 D3 formation

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Parodontosis is treated by means of antioxidants. Which of the following natural compounds is used as an antioxidant:

Choline

Thiamine

Tocopherol

Pyridoxine

Gluconate

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A patient has high sunlight sensitivity of skin. During standing his urine turns dark-brown. What is the most probable cause of this condition?

Pellagra

Porphyria

Alkaptonuria

Haemolytic jaundice

Albinism

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Periodontitis is accompanied by activation of proteolysis in the periodontium tissues. The evidence of proteolysis activation is increase of the following component of oral liquid:

Amino acids

Organic acids

Glucose

Cholesterol

Biogenic amines

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A patient has been diagnosed with alkaptonuria. This pathology is caused by deficiency of the following enzyme:

Oxidase of homogentisic acid

Phenylalanine hydroxylase

Glutamate dehydrogenase

DOPA decarboxylase

Pyruvate dehydrogenase

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An experimental rat got intraabdominal injection of 10 ml of 40% glucose solution. 60 minutes later the rat passed into a comatose state as a result of dehydratation. What is the mechanism of development of this state?

Acid-base disbalance

Rise of osmotic pressure of extracellular fluid

Rise of oncotic pressure of extracellular fluid

Loss of salts and water

Reduction of vasopressin secretion

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A 62 year old patient with cerebral haemorrhage was admitted to the neurological department in grave condition. Objectively: increase of respiration depth and rate with its following reduction to apnoea, thereafter respiration cycle restores. What respiration type is it?

Kussmaul’s

Cheyne-Stokes

Gasping

Biot’s

Apneustic

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Patients suffering from relapsing typhus have fever that can be characterized by several days of high temperature alternating with periods of normal temperature. Such temperature curve is called:

Febris continua

Febris hectica

Febris atypica

Febris recurrens

Febris intermittens

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Poisoning with corrosive sublimate caused acute renal insufficiency. Its progress included four stages: 1) initial, 2) oligoanuria, 4) recovery. Name the third stage of acute renal insufficiency:

Hemodynamic

Polyuric

Pathochemical

Ischemic

Metabolic

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A 48 year old male patient was admitted to the hospital with acute attack of chronic glomerulonephritis. Examination revealed chronic renal failure. What is the cause of hyperazotemia by chronic renal failure?

Reduction of glomerular filtration

Reduction of tubular reabsorption

Disorder of protein metabolism

Disorder of water-electrolytic metabolism

Reduction of tubular excreation

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Examination of experimental rats that have been getting only carbohydrate feed for a long time revealed accumulation of water in tissues. What is the leading pathogenetic mechanism of edema development?

Membranogenic

Dysregulatory

Hypooncotic

Lymphogenous

Hyperosmolar

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Examination of a patient 24 hours after appendectomy revealed neutrophilic leukocytosis with regenerative shift. What is the most probable mechanism of development of absolute leukocytosis in peripheral blood?

Redistribution ofleukocytes in the organism

Slower emigration of leukocytes to the tissues

Reduction of leukolysis

Immunity activation

Intensification of leukopoiesis

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A patient suffering from chronic myeloleukemia has got the following symptoms of anemia: decreased number of erythrocytes and low haemoglobin concentration, oxyphilic and polychromatophilic normocytes, microcytes. What is the leading pathogenetic mechanism of anemia development?

Substitution of haemoblast

Chronic haemorrhage

Intravascular hemolysis of erythrocytes

Reduced synthesis of erythropoietin

Deficiency of vitamin B12

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Autopsy of a dead patient revealed that pia mater was dull, there were greenish-yellow overlays covering almost all convexital surface of cerebral hemispheres. Histological examination revealed extreme hyperemia of maters along with diffuse leukocytic infiltration. What is the most probable diagnosis?

Meningococcal infection

Measles

Tuberculosis

Influenza

Anthrax

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Examination of puncture biopsy material of liver revealed dystrophy of hepatocytes, their necrosis and sclerosis along with disturbance of beam and lobulous structure and formation of pseudolobules of regeneration nodes. What is the most probable diagnosis?

Liver cirrhosis

Acute hepatitis

Chronic hepatitis

Progressing massive liver necrosis

Chronic hepatosis

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A 6 year old child was delivered to the hospital because of measles pneumonia. On the mucous membrane of a cheek a dentist revealed an ill-defined greish area 2x2,5 cm large. Soft tissues are edematic and foul-smelling. The most probable diagnosis of the dentist should be:

Gangrenous stomatitis

Ulcerous stomatitis

Noma

Pustular stomatitis

Phlegmonous stomatitis

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A patient has deformation of jaw bones. Histological examination revealed there growth of fibrocellular tumourlike ill-defined tissue with primitive osteogenesis. What disease are these presentations typical for?

Ameloblastoma

Parathyroid osteodystrophy

Osteosarcoma

Eosinophilic granuloma

Fibrous dysplasia

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A 55 year old man had been suffering from chronic glomerulonephritis. He died from chronic renal failure. Macroscopi-cal examination revealed on the surface of epicardium and pericardium some greyish-white villous depositions. After their removal dilated and plethoric vessels were uncovered. What process took place in the pericardium?

Proliferative inflammation

Organization

Fibrinous inflammation

Arterial hyperemia

Haemorrhagic inflammation

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Autopsy of a 68 year old man who died from chronic cardiac insufficiency revealed deformed, thickened, conjoined cusps of mitral valve. Along the edge of joining there were small (1-2 mm) thrombs. What form of endocarditis caused development of chronic cardiac insufficiency?

Polypoulcerous

Recurrent verrucous

Diffuse

Acute verrucous

Fibroplastic

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A 42 year old patient who had been suffering from chronic granulomatous periodontitis and chronic purulent osteomyelitis of his lower jaw for 8 years died from chronic renal insufficiency. What complication of purulent osteomyelitis has developed in kidneys?

Adipose degeneration

Necrosis of epithelium of convoluted tubules

Amyloidosis

Hyalinosis

Atrophy

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A 5 year old child has the following symptoms: body temperature up to 40oC, acute headache, vomiting, anxiety, shiver. 4 days later there appeared hemorrhagic skin rash, oliguria and adrenal insufficiency that caused death. Bacteriological examination of pharyngeal smears revealed meningococcus. What form of meningococcal infection was it?

Meningococcemia

-

Meningoencephalitis

Meningococcal nasopharyngitis

Meningococcal meningitis

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A 75 year old male patient consulted a surgeon about a brown nonhealing ulcer of shin. Examination of biopsy material revealed diffuse growth of polymorphic atypic cells with brown pigment in their cytoplasm. Pearls reaction was negative. There were also a lot of pathological mitoses and foci of tissue necrosis. What is the most probable diagnosis?

Local hemosiderosis

Trophic ulcer

Intradermal nevus

Melanoma

Skin cancer

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Autopsy of a man who had been suffering from hypertension revealed in his brain a cavity with rubiginous walls. What event preceded development of these changes?

Haematoma

Diapedetic haemorrhages

Ischemic infarction

Abscess

Plasmorrhagias

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Medical examination of the first-year pupils included Mantoux test. 15 pupils out of 35 had negative reaction. What actions should be taken against children with negative reaction?

Examination of blood serum

Antitoxin vaccination

Repeat Mantoux test

BCG vaccination

Rabies vaccination

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On a certain territory mass death of rodents was registered. It was suspected that their death might have been caused by plague. What serological reaction should be applied for quick identification of antigen of the causative agent of this epizooty?

Neutralization

Agglutination

Complement binding

Precipitation

Passive hemagglutination

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A 10 year old child underwent Mantoux test (with tuberculin). 48 hours later there apperaed a papule up to 8 mm in diameter on the site of tuberculin injection. Tuberculin injection caused the following hypersensitivity reaction:

II type hypersensitivity reaction

IV type hypersensitivity reaction

Seroreaction

Atopic reaction

Arthus reaction

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A 58 year old female patient had to be prepared to cholecystectomy. Complex of premedication drugs included benzohexonium. What is the function of this drug in anaesthesia?

Relaxation of skeletal muscles

Reduction of excitement phase

Functional block of visceral reflexes

Intensification of retrograde amnesia

Relaxation of smooth muscles

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A patient had an attack of bronchial asthma in the dentist’s office. The attack was arrested by salbutamol. This drug relates to the following group of therapeutic agents:

/32-adrenomimetics

a-3-adrenomimetics

3 i-32-adrenomimetics

Sympatholytics

a-adrenomimetics

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A patient with acute duodenal ulcer was admitted to the hospital. Analysis of gastric juice revealed hyperfunction of secretion and acid-forming in stomach. Choose a drug that can reduce secretory function of stomach due to inhibition of H2-receptors:

Atropine

Ranitidine

Methacin

Platyphyllin

Extract of dry belladonna

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A patient was administered clonidi-ne to be taken parenterally in case of abrupt rise of arterial pressure. What is its mechanism of action?

Stimulation of central imidazole1-receptors

Block of a1- and a2-adrenoreceptors

Block of nicotinic cholinoreceptors of ganglia

Block of a 1 -adrenoreceptors

Stimulation of central a2- adrenoreceptors

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A patient was prescribed a drug with apparent lipophilic properties. What is the main mechanism of its absorption?

Active transport

Pinocytosis

Binding with transport proteins

Filtration

Passive diffusion

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A patient noticed symptoms of approaching attack of bronchial asthma and took several tablets one by one at short intervals out of the doctor’s control. Short-term improvement of his condition came only after taking the first two tablets. Next intakes of a drug didn’t improve his condition. Reduction of the drug effectiveness was caused by:

Cumulation

Addiction

Dependence

Tachyphylaxis

Idiosyncrasy

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A patient with streptococcal infection of gums was prescribed a drug that contained betalactam ring in its structure. Whi- ch drug relates to this group?

Chloramphenicol

Rifampicin

Benzylpenicillin

Erythromycin

Streptomycin sulfate

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It was necessary to determine absolute gustation thresholds of a healthy man for different substances. The lowest threshold will be observed for the following substance:

Citric acid

Glucose

Sodium chloride

Quinine

Saccharose

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A patient with neck injury was admitted to the hospital. Examination revealed a damaged nerve located anteriad to the frontal scalene. What nerve is damaged?

Cervical part of sympathetic trunk

Phrenic

Sublingual

Vagus

Glossopharyngeal

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A 38 year old patient takes aspirin and sulfanilamides. After their intake intensified erythrocyte haemolysis is observed which is caused by deficiency of glucose 6-phosphate dehydrogenase. This pathology is caused by failure of the following coenzyme:

NADP - H

Pyridoxal phosphate

FAD - H2

FMN - H2

Ubiquinone

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After a road accident a driver has got deformity in the midle third of his left shin and intense pain, especially when he tries to move his left shin. The ends of a trihedral bone stick out of a wound, there is great blood loss. What bone might be damaged?

Patella

Femur

Fibula

Astragalus

Tibia

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A histological specimen presents the tissue that contains cells having no processes and a few tens of nuclei each. One of cell surfaces has a corrugated zone that provides secretion of hydrolytic elements. What tissue is it?

Muscular tissue

Osseous tissue

Cartilaginous tissue

Nerve tissue

Epithelial tissue

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Potassium cyanide that is a poison came into a patient’s organism and caused death a few minutes after it. The most probable cause of its toxic effect was abnormal activity of:

Catalase

Haemoglobin synthesis

ATP-synthetase

NADP — H-dehydrogenase

Cytochrome oxidase

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Abnormal chromosome disjunction during meiosis resulted in formation of: an ovum with 22 autosomes and polar body with 24 chromosomes. If such an ovum would be fertilized with a normal spermatozoon (22 + X) the child might have the following syndrome:

Trisomy X

Edwards’ syndrome

Turner’s syndrome

Klinefelter’s syndrome

Down’s syndrome

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A patient underwent Caesarean section. During the operation a long incision was made in the uterus wall and the fetus was extracted from uterus. Healing of the sutured myometrium will proceed in the following way:

Proliferation of myosatellitocytes

Hypertrophy of smooth myocytes

Formation of smooth muscular tissue

Formation of a fibrous cicatrix

Formation of cross-striated muscle fibers

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Rheography of an 18 year old student during exercise showed redistribution of blood flow between organs. The peak blood flow will be observed in the following vessels:

Gastrointestinal tract

Cerebrum

Kidneys

Skeletal muscles

Liver

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Microscopical examination of exudate obtained from a rat with aseptic peritoni- tis and mixed with bird’s erythrocytes revealed macrophages surrounded by foreign erythrocytes. What stage of phagocytosis is it?

Adherence

Immersion

Uncomplete phagocytosis

Approaching

Intracellular digestion

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On the 2nd day after myocardium infarction the patient’s systolic arterial pressure abruptly dropped down to 60 mm Hg. This was accompanied by tachycardia up to 140 bpm, dyspnea, loss of consciousness. What is the leading mechanism in the pathogenesis of this shock?

Decrease of stroke volume

Decrease of circulating blood volume

Paroxysmal tachycardia

Intoxication by the products of necrotic degeneration

Anaphylactic reaction to myocardial proteins

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A 35 year old patient complains about permanent thirst, poor appetite. He drinks 9 l water per day. Daily diuresis is increased, urine is colourless, its relative density is 1,005. The most probable cause of this pathology development is damege of:

Hypothalamic nuclei

Epiphysis

Adenohypophysis

Basal membrane of glomerular capillaries

Epithelium of renal tubuli

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A patient with disfunction of external respiration has to undergo tracheotomy. The isthmus of thyroid gland is commonly situated on a level with the following tracheal rings:

III-IV

I-II

V-VI

II- IV

IV-V

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Active physical work induces rise of concentration of carbonic acid in blood. This causes deepening and acceleration of respiration thus reducing concentration of carbonic acid and hydrogen ions in blood. This maintains the following process:

Homeostasis

Orthobiosis

Anabiosis

Immunity

Ontogenesis

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Pathological process of purulent barotitis involves an artery on the anterior wall of tympanic cavity. What artery is it? A.

A. meningea media

carotis interna

A. auricularis posterior

A. temporalis superficialis

A. carotis externa

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A 34 year old male patient cosulted a doctor about face carbuncle. Objectively: a loose, painless edema of hypodermic tissue; black crust in the centre of carbuncle, vesicular rash around it. Microbiological examination revealed static streptobacilli capable of capsule building. What microorganisms are the causative agents of this disease?

Bacillus antracis

Bacillus anthracoides

Bacillus megaterium

Staptylococcus aureus

Bacillus subtilis

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A 38 year old patient complained that after acute respiratory viral disease she had lost sensation of food contact with the front 2/3 of her tongue as well as pain and temperature sensation (burned her tongue with hot tea). Which nerve and which branch of it was damaged?

Lingual nerve of mandibular branch of trigeminus

Tympanichord of facial nerve

Lingual branches of glossopharyngeal nerve

Lingual nerves of sublingual nerve

Superior laryngeal nerve of vagus

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Microscopical examination of coronary artery of a 53 year old dead man revealed luminal narrowing of the vessel because of fibrous plaque mixed with lipides. The most probable form of atherosclerosis is:

Lipoidosis

Ulceration

Atheromatosis

-

Liposclerosis

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A blood sample of a pregnant woman was typed. Erythrocyte-agglutination reaction was present with standard sera 0a, P(I), Ba(III), reaction was absent with the serum Ap(II). The blood under examination relates to the following group:

AB(IV)

Ap(II)

0 a, p(I )

Ba(III)

-

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A female patient suffering from acute bronchitis complains about respiratory obstruction and cough with thick viscous sputum. She was prescribed a mucolytic agent that stimulates surfactant synthesis. What mucolytic agent was prescribed?

Sodium hydrocarbonate

Glaucin

Morphine hydrochloride

Ambroxolum

Theophylline

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Coprological examination of a patient’s feces revealed small operculate eggs. It is known from the anamnesis that the patient often consumes fish. What fluke parasitizes in the patient’s organism?

Cat liver fluke

Lancet fluke

Liver fluke

Blood fluke

Lung fluke

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Clinical examination of a female patient revealed reduction of basal metabolism by 40%, gain in body mass, drop of body temperature, face puffiness, sexual disfunctions, inertness and apathy, lowered intelligence. These symptoms are caused by disfunction of the following endocrine gland:

Hypofunction of thyroid gland

Hypophysis hyperfunction

Hyperfunction of thyroid gland

Hypofunction of parathyroid glands

Epiphysis hypofunction

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During a neuro-surgical operation the occipital areas of cerebral cortex are stimulated. What sensations will the patient have?

Tactile

Olfactory

Auditory

Visual

Gustatory

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Microscopic study of an endocrine gland revealed that its parenchyma consisted of follicular structures. Their wall was formed by monolayer cubic epithelium, and their cavity was filled up with oxyphilic substance. What hormon is secreted by this gland?

Oxytocin

Parathyrin

Aldosterone

Cortisol

Thyroxin

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During starvation normal rate of glucose is maintained by means of activation of gluconeogenesis. What substance can be used as a substrate for this process?

Ammonia

Urea

Adenine

Alanine

Guanine

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What chnges will be observed in an isolated heart after introduction of adrenaline into the perfusion solution?

Increase of heart rate and force

Diastolic arrest

Decrease of heart force

Increase of heart rate

Increase of heart force

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A sportsman needs to improve his sporting results. He was recommended a drug containing carnitine. What process is activated by this compound in the first place?

Transport of amino acids

Transport of fatty acids

Transport of calcium ions

Transport of vitamin K

Transport of glucose

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A patient consulted a doctor about acute pain in the right subcostal area. During examination the doctor noticed yellowed sclera of the patient. Laboratory analyses revealed high activity of alanine-aminotransferase and negative reaction to stercobilin in feces. What disease are these symptoms typical for?

Haemolytic jaundice

Cholelithiasis

Chronic colitis

Chronic gastritis

Hepatitis

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A patient was admitted to a hospital with poisoning with unsound food. His stomach was lavaged with solution of potassium permanganate. What is its mechanism of action?

Disturbance of synthesis of respiratory chain enzymes

Release of iodine

Destruction of bacteria membranes

Release of atomic oxygen

Release of chlorine

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A patient complained about ear noise and pain sensations. Objectively: the patient has acute respiratory disease, rhinitis. The infection penetrated into the tympanic cavity through the following opening of the pharynx:

Choanae

Fauces

Aperture of larynx

Pharyngeal opening of auditory tube

Tympanic opening of auditory tube

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A 3 month old infant has got a white deposition on the mucous membrane of his mouth, tongue and lips. The doctor suspected candidosis. What nutrient medium should be used for inoculation of the material under examination in order to confirm this diagnosis?

Endo

Clauberg

Loewenstein-Jensen

Roux

Sabouraud

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Specific prophylaxis involved application of a vaccine containing microorganisms and exotoxin detoxicated by formalin. It relates to the following type of vaccine:

Combined

Chemical

Live

Anatoxin

Genetically engineered

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A 70 year old patient suffering from cardiac insufficiency has been uncontrolledly taking digoxin that resulted in extrasystole, vomiting, vision impairment, anxiety, sleep disturbance, reduction of diuresis. Application of drugs relating to the following group will be pathogenetically reasonable in this case:

Donators of sulfhydric groups

Potassium channel blockers

Stimulants of pi-adrenoreceptors

Donators of nitrogen oxide

Angiotensin II receptor blockers

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A patient suffering from hepatocerebral degeneration has low cncentration of ceruloplasmin in blood serum. What element accumulation will be observed in liver, cerebrum and kidneys of the patient?

Cuprum

Ferrum

Calcium

Sodium

Potassium

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Electron-microscope investigation of cortical substance of a kidney reveals some structures lined with prismatic epithelium that normally has brush border and deep plicae of plasmolemma in its basal part. There is a big number of mi-tochondrions between these plicae. These structures belong to the following part of a nephron:

Distal convoluted tubule

Proximal tubule

Henle’s loop

Distal straight tubule

Renal corpuscle

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Intralobular capillaries of a liver specimen have wide irregular lumen. Basal membrane is absent in the major part of the capillary. What type of capillaries is it?

Visceral

Postcapillaries

Sinusoid

Precapillaries

Somatic

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In order to speed up healing of the thermal injury it is required to prescribe a drug that facilitates epithelization of skin and mucous membranes. What drug is it?

Ergocalciferol

Ascorbic acid

Nicotinic acid

Tocopherol acetate

Retinol acetate

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A patient with ventricular arrhythmia was admitted to the cardiological department. What drug should be administered?

Amiodarone

Drotaverine

Amlodipine

Aminazine

Proserin

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After restoration of blood circulation in damaged tissue accumulation of lactate comes to a stop and speed of glucose consumption slows down. These metabolic changes are caused by activation of the following process:

Anaerobic glycolysis

Gluconeogenesis

Lipolysis

Aerobic glycolysis

Glycogen biosynthesis

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Researches of the latest decades established that immediate 'executors' of cell apoptosis are special enzymes called caspases. Generation of one of them proceeds with participation of cytochrome What is its function in a normal cell?

Component of H + ATP system

Enzyme of tricarboxylic acid cycle

Enzyme of respiratory chain of electron transport

Enzyme of beta-oxidation of fatty acids

Component of pyruvate-dehydrogenase system

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A patient with essential hypertension was admitted to the cardiological department. In order to lower arterial pressure a doctor prescribed a drug that blocks pi and ^-adrenoreceptors. What drug is it?

Proserin

Prednisolone

Celecoxib

Indometacin

Propranolol

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A patient with myocardium infarction was delivered to the resuscitation department. What drug should be injected to the patient for prophylaxis of pain shock?

Analgin

Celecoxib

Promedol

Paracetamol

Naloxone

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A patient with myocardium infarction was admitted to the resuscitation department. What drug should be injected to the patient in order to prevent thrombosis?

Heparin

Chingamin

Thyroxine

Biseptol-480

Dimedrol

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A 28 year old woman consulted a doctor about sterility. Examination revealed underdeveloped ovaries and uterus, irregular menstrual cycle. Study of sex chromatin revealed 2 Barr’s bodies in most somatic cells. What chromosome disease is the most probable in this case?

Triplo-X syndrome

Turner’s syndrome

Klinefelter’s syndrome

Edwards’ syndrome

Patau’s syndrome

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Treatment of many diseases involves use of cocarboxylase (thiamine pyrophosphate) for supplying cells with energy. What metabolic process is activated in this case?

Glutamate deamination

Decarboxylation of biogenic amines

Amino acids decarboxylation

Oxidizing decarboxylation of pyruvate

Detoxication of harmful substances in liver

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A patient with apparent icteri-tiousness of skin, sclera and mucous membranes was admitted to the hospital. The patient’s urine was of brown ale colour, analysis revealed presence of direct bilirubin. Feces had low concentration of bile pigments. What type of jaundice is it?

Absorbtion

Obturative

Conjugated

Haemolytic

Parenchymatous

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A patient suffers from chronic left-ventricular insufficiency. What drug should be prescribed?

Bemegride

Etimizol

Digoxin

Vinpocetine

Pyracetam

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Medical ambulance delivered a 2 year old girl to the children’s department. Objectively: the child is inert, apathetic. Liver is enlarged, study of biopsy material revealed glycogen excess. Blood glucose rate is below normal. The most probable cause of hypoglycemia is:

Low activity of glucose 1-phosphate uridine transferase

Low activity of glucose 6-phosphatase

High activity of glucokinase

Low activity of glycogen synthase

Low activity of glycogen phosphorylase

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A 22 year old woman has been taking sulfanilamides for a long time that led to symptoms of hemolytic anaemia caused by hereditary disturbance of synthesis of glucose 6-phosphate dehydrogenase. This enzyme of pentose-phosphate cycle is responsible for generation of:

NAD

ATP

NADP - H2

FMN

FAD

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A patient suffering from non-insulin-dependent diabetes mellitus was prescribed glibenclamid internally. What is the mechanism of its hypoglycemic action?

It stimulates generation of endogenous insulin by beta cells

It intensifies utilization of glucose by peripheral tissues

It inhibits alpha glucosidase and polysaccharide breakdown

It inhibits gluconeogenesis in liver

It inhibits glucose absorption in the bowels

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During the preventive examination of a miner a doctor revealed changes in cardiovascular fitness being evidence of cardiac insuffisiency at a stage of compensation. What is the main evidence of compensation of cardiac activity?

Cyanosis

Tachycardia

Rise of arterial pressure

Dyspnea

Myocardium hypertrophy

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A typical symptom of cholera is great loss of water and sodium ions. What mechanism underlies development of diarrhea in this case?

Increased secretion of renin by the cells of renal arterioles

Increased corticotropin synthesis

Activation of adenylate cyclase of enterocytes

Inhibition of vasopressin synthesis in hypothalamus

Aldosterone oxidation in adrenal cortex

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A newborn has signs of dyspepsia after milk feeding. Symptoms of dyspepsia disappear when milk is substituted for glucose solution. The newborn has low activity of the following enzyme:

Invertase

Amylase

Maltase

Lactase

Isomaltase

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A 35 year old man got a trauma that resulted in complete rupture of spinal cord at a level of the first cervical segment. What changes of respiration will be observed?

Respiration will become infrequent and deep

Respiration will come to a standstill

Respiration won’t change

Respiration will become diaphragmatic

Respiration will become frequent and shallow

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During an experiment the median part of an animal’s cochlea was damaged. This resulted in impaired perception of acoustic vibrations of the following frequency:

Medium

High and medium

Low and medium

High

Low

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A man got poisoned with mushrooms. They contain muscarine that stimulates muscarinic cholinoreceptors. What symptom is typical for poisoning with inedible mushrooms?

Arterial pressure rise

Miosis

Mydriasis

Heart rate rise

Bronchi dilation

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A patient suffering from syphilis was prescribed a drug the action of which based upon disturbed generation of murein leading to death of the causati- ve agent. What drug is it?

Benzylpenicillin sodium salt

Doxycycline hydrochloride

Bijochinol

Azithromycin

Ciprofloxacin

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A patient suffering from chronic bronchitis takes a synthetic mucolytic drug that stimulates sputum liquefaction. What drug is it?

Heparin

Enalapril

Acetylcysteine

Diazepam

Furosemide

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A microspecimen of parotid gland presents secretory acines with serous cells that synthesize mostly enzymes. According to the chemical composition classification, the parotid gland relates to the following glands:

Enzymatic

Mucous

Seromucous

-

Serous

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After mouth opening the mouth closed reflectory. What receptors initiate this reflex?

Proprioceptors of depressor muscles of mandible

Periodontium receptors

Mechanoreceptors of oral mucous membrane

Proprioceptors of elevator muscles of mandible

Gustatory receptors

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After continuous treatment with antibiotics a patient got symptoms of stomatitis. Examination of specimens of oral mucous membrane revealed some oval polymorphous Gram-positive microorganisms arranged in clusters. What microorganism may be the cause of such manifestations?

C.pylori

S.pyogenes

S.aureus

C.perfringens

C.albicans

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After mouth closing and teeth clenching the mouth opens reflectory. What receptots initiate this reflex?

Gustatory receptors

Proprioceptors of depressor muscles of lower jaw

Proprioceptors of elevator muscles of lower jaw

Receptors of periodontium

Mechanoreceptors of oral mucous membrane

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Examination of a female patient revealed low activity of lipoprotein lipase which hydrolyzes chylomicron triglycerides on the surface of endothelium of adipose tissue capillaries. What biochemical disorders should be expected?

Type III hyperlipoproteinemia

Type II A hyperlipoproteinemia

Type II B hyperlipoproteinemia

Type I hyperlipoproteinemia

Type IV hyperlipoproteinemia

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A child has physical and mental retardation, serious abnormalities in connective tissue of internal organs; urine contains keratan sulfates. This is caused by metabolic disorder of the following substance:

Elastin

Collagen

Glycosaminoglycan

Fibronectin

Hyaluronic acid

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A 40 year old female patient has enlarged thyroid gland. On palpation the gland is dense, its surface is slightly tuberous. Histological examination of gland sample revealed diffuse infiltration of tissue by the cells, formation of lymphoid follicles. What disease is it?

Diffuse toxic goiter

Endemic goiter

Sporadic goiter

Autoimmune thyroiditis

Riedel’s disease

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A 30 year old woman has been continuously using lipstick with a fluorescent substance that led to development of a limited erythema on the prolabium, slight peeling, and later small transversal sulci and fissures. Microscopical examination of the affected zone revealed in the connective tissue sensibilized lymphocytes and macrophages, effects of cytolysis. What type of immunological hypersensitivity has developed on the lip?

Granulomatosis

IV type (cellular cytotoxicity)

I type (reagin type)

III type (immune complex cytotoxicity)

II type (antibody cytotoxicity)

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A patient suffering from essential arterial hypertension got hypertensic crisis that caused an attack of cardiac asthma. What is the leading mechanism of cardiac insufficiency in this case?

Cardiac overload due to increased blood volume

Disturbed blood inflow to the heart

Absolute coronary insufficiency

Cardiac overload due to increased resistance

Myocardium damage

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A patient who has been taking a certain drug for a long time cannot discontinue the use of it because this causes psychic and somatic disfunctions. The syndrome occuring at refraining from the use of a drug is called:

Abstinence

Cumulation

Sensitization

Idiosyncrasy

Tachyphylaxis

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A 43 year old female patient was admitted to the hospital with complaints of pain in the right subcostal area, skin itch. Examination revealed hypalgesia and hematolysis, skin icteritiousness, bradycardia, hypotonia. What is the most probable cause of these symptoms?

Hepatocellular jaundice

Cholemia

Parenchymatous jaundice

Intensification of erythrocyte haemolysis

Diabetes mellitus

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A patient underwent partial removal of a structure of central nervous system by medical indications. This resulted in development of atony, astasia, intention tremor, ataxia, adiadochokinesis. What structure of CNS was partially removed?

Cerebellum

Basal ganglions

Motor cortex

Amygdaloid complex

Hippocampus

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Blood analysis of a patient suffering from jaundice revealed increase of total bilirubin by its indirect fraction. Urine and feces have intense colouring. What is the most probable mechanism of these abnormalities?

Increased haemolysis of erythrocytes

Obstruction of bile outflow from the liver

Impaired generation of direct bilirubin

Impaired transformation of urobilinogen in the liver

Damage of liver parenchyma

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What contraction of upper extremity muscles will be observed during holding (but not moving) a load in a certain position?

Excentric

Isotonic

Concentric

Auxotonic

Isometric

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A patient has roundish ulcers on his face, inflammation and enlargement of lymph nodes. These symptoms turned up as a result of mosquito bites. Laboratory examination of discharge from the ulcers revealed unicellular aflagellar organisms. What is the most probable diagnosis?

Scabies

Toxoplasmosis

Dermatotropic leishmaniasis

Myasis

Trypanosomiasis

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A patient has been suffering from diabetes mellitus for 5 years. As a result of not keeping to a diet the patient passed into a comatose state. Emergency doctor injected him glucose. The patient’s state got better. What is the most probable type of coma in this case?

Hyperglycemic

Hypothyreoid

Hepatic

Acidotic

Hypoglycemic

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A patient was admitted to the infectious diseases department. His skin was dry, with low turgor; he had rice-water stool. The patient was diagnosed with cholera. This disease is ordinarily accompanied by the folowing disorder of water-electrolytic balance:

Hyperosmotic hypohydration

Hyposmotic hyperhydration

Hypoosmotic hypohydration

Isoosmotic hypohydration

Hyperosmotic hyperhydration

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A specimen of connective tissue of derma was stained with Sudan III and hematoxylin. There are clusters of big polygonal cells that turned orange. Their nuclei are flattened and located on periphery. What tissue is it?

Reticular connective

Lamellar osseous

White adipose

Brown adipose

Hyaline cartilaginous

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For the purpose of anaesthetization a patient got injection of local anesthetic. A few minutes later the patient got dyspnea and tachycardia; he lost consciousness. What type of shock is it?

Cardiogenic

Haemorrhagic

Burn

Anaphylactic

Traumatic

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A new-born child has hyperemia, edema of the oral mucous membrane, small erosions with viscous mucopus. Smears from the mucopus contain a lot of leukocytes with Gram-negative diplococci. The same microorganisms can be found also beyond the leukocytes. What is the most probable diagnosis?

Toxoplasmosis

Blennorrhea

Staphylococcal stomatitis

Gonococcal stomatitis

Congenital syphilis

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Examination of a tissue sample of enlarged cervical lymph nodes taken from a young woman revealed proliferation of lymphocytes, reticular cells, macrophages, big and small Hodgkin’s cells, multinuclear Sternberg-Reed cells. There were also multiple eosinophils, single foci of caseous necrosis of the node tissue. What is the most probable diagnosis?

Metastasis of lung cancer

Acute leukosis

Lymphosarcoma

Lymphogranulomatosis

Tuberculosis

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Microscopical study of discharges from urethra of a patient suffering from acute urethritis revealed bean-shaped microorganisms up to 1 micrometer in diameter arranged in pairs and placed inside the leukocytes. What microorganisms are these?

Tetracocci

Streptococci

Gonococci

Meningococci

Staphylococci

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A patient with fracture of femoral bone in the area of surgical neck got symptoms of acute dextroventricular insufficiency as a result of pulmonary embolism. What type of embolism is it?

Metastatic

Tissue

Air

Fat

Gas

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A patient has dislocation of his mandible that caused impairment of salivation and gustatory sensitivity of anterior 2/3 of his tongue. What nerve was damaged?

Tympanichord

Lesser petrosal nerve

Sublingual nerve

Deep petrosal nerve

Greater petrosal nerve

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A 40 year old male patient died from cerebral edema. In anamnesis the face carbuncle was registered. Autopsy revealed hyperemia and edema of cerebral tissue. White matter of the left hemisphere had two cavities 6x5,5 and 5x4,5 cm large filled with yellowish-green cream-like fluid. Walls of the cavities were built up by nerve tissue with irregular rands. What complication of carbuncle was it?

Acute abscesses

Empyema

Colliquative necroses

Chronic abscesses

Cysts

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A dentist was examining oral cavity of a 9 year old child in the buccal surface of gingiva in the area of the lower canine he revealed a red, soft, node-like formation 1 cm in diameter that started immediately bleeding when touched. Microscopical examination revealed that this formation consisted of many small vessels like venules and capillaries separated by thin layers of connective tissue, with focal infiltration by lymphoid and plasmatic cells. Such changes are typical for:

Capillary hemangioma

Radicular granuloma

Angiomatous epulis

Fibrous epulis

Papilloma

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In the surgical department of a dental clinic cases of hospital-acquired staphylococcal infection were registered which was caused by strains with multiple drug resistance. Such feature can be identified by presence of:

R-plasmids

Temperate bacteriophages

Virulent bacteriophages

F-plasmids

Exotoxins

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Roentgenological examination of a patient revealed a deformity of the inferior wall of the right eye socket. What paranasal sinus was most probably damaged?

Right ethmoidal labyrinth

Sphenoidal sinus

Right maxillary sinus

Left ethmoidal labyrinth

Frontal sinus

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During examination a dentist revealed cervical caries of right inferior incisors as well as enlargement of a certain group of lymph nodes. What lymph nodes are enlarged?

Facial

Occipital

Superficial cervical

Deep cervical

Submental

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Examination of a tubular organ revealed that its middle membrane consisted of solid hyaline rings. What epithelium lines mucous membrane of this organ?

Multinuclear prismatic ciliated

Monolayer prismatic with a limbus

Monolayer cubic

Multilayer squamous nonkeratinous

Monolayer prismatic glanduous

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What method should be applied for sterilization of heatproof and moi-stureproof stomatological instruments in order to ensure total destruction of vi- ruses, vegetative and spore forms of microorganisms?

Boiling

Pasteurization

Autoclaving

Tyndallization

Burning in the flame of gas burner

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A female patient was admitted to the hospital with pleuritis. Which area of pleural cavity contains most exudate?

Under the pleural cupula

Under the pulmonary radix

Phrenicomediastinal recess

Costomediastinal recess

Costodiaphragmatic recess

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A 10 month old child has high excitability, sleep disturbance, amyotonia, retarded dentition, teeth erupt with inadequate enamel calcification. These changes are caused by deficiency of the following vitamin:

Cholecalciferol

Retinol

Thiamine

Riboflavin

Nicotinamide

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Examination of nasal cavity revealed deviation of the posterior part of nasal septum. What bone is affected?

Vomer

Medial plate of pterygoid process

Lateral plate of pterygoid process

Perpendicular plate of ethmoid bone

Vertical plate of palatine bone

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During embryogenesis the epithelial band also known as vestibular plate gives rise to development of vestibule of mouth. What biological mechanism of the programmed death of cells provides growth of buccolabial sulcus from epithelial plate?

Paranecrosis

Meiosis

Apoptosis

Amitosis

Necrosis

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Roentgenological examination of mandible of a 27 year old man revealed a focus of osseous tissue destruction. Histological examination revealed a tumour consisting of odontogenous epithelium cords, immature connective tissue and dysplastic dentin rests. What tumour is it?

Odontoameloblastoma

Odontogenous fibroma

Complex odontoma

Ameloblastic fibro-odontoma

Dentinoma

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A male patient underwent an operation on account of inguinal hernia. During the operation a surgeon damaged content of the inguinal canal. What structure was damaged?

Lig. inguinale

Urarchus

Funiculus spermaticus

-

Lig. teres uteri

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A patient with fracture of the greater wing of sphenoid bone was admitted to the craniocerebral department. The fracture line went through the spinous foramen. What vessel was damaged?

Lateral pterygoid artery

Anterior deep temporal artery

Posterior deep temporal artery

Superficial artery

Middle meningeal artery

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A patient has allergic rhinitis with profuse mucous discharges, itching, frequent sneezing. What drug should be chosen if you know that it selectively blocks histamine receptors?

Naphthizin

Prednisolone

Loratadine

Adrenaline hydrochloride

Mesatonum

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A patient with myocardium infarction was admitted to the cardiological department. In order to relieve his pain it was decided to potentiate action of fentanyl by a certain neuroleptic. What is the most suitable neuroleptic for neuroleptanalgesia?

Haloperidol

Droperidol

Triftazine

Sulpiride

Aminazine

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During examination of a child’s oral cavity a pediatrician established presence of inferior medial incisors. The child’s development is normal. How old is the child?

10-12 months

13-14 months

8-9 months

-

6-7 months

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A 23 year old man got perforation of hard palate. There was also a solid well-defined formation. Post-operative microscopical examination of this formation revealed a large focus of caseous necrosis surrounded by granulation tissue with endovasculitis and cellular infiltrate consisting mainly of plasmocytes but also of lymphocytes and epithelioid cells. What is the most probable diagnosis?

Tuberculosis

Lepra

Sarcoma

Scleroma

Syphilis

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A young woman has entered a production unit where strongly smelled of paints and varnishes and had bronchospasm. This reflex was provoked by irritation of the following receptors:

Juxtaglomerular

Central chemoreceptors

Irritant

Pleural receptors

Peripheral chemoreceptors

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A histological specimen presents an organ that has both cortical and medullary substance. Cortical substance consists of an external zone that contains lymph nodules as well as of a paracortical zone. Medullary substance contains medullary cords, sinuses and trabecules. What organ possesses these morphological signs?

Kidney

Thymus

Adrenal glands

Lymph node

Spleen

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A ventral root of spinal cord was damaged as a result of a trauma. The following processes of the following neurons were damaged:

Dendrites of motor neurons

Dendrites of sensory neurons

Axons of sensory neurons

Dendrites of internuncial neurons

Axons of motor neurons

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A 7 year old child has angina. A smear from the tonsil surface was inoculated on blood agar. 24 hours later there had grown colonies of streptococci. Nutrient medium turned transparent around them. This study revealed presence of the following pathogenous factor:

Beta-lactamase

Hemolysin

Leukocidin

Endotoxin

Neuraminidase

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Hurtnup’s disease is caused by point mutation of only one gene. This results in abnormal absorption of tryptophane in the intestine as well as its abnormal reabsorption in renal tubules. This causes synchronous disorders in digestive and urinary excretion systems. What genetic phenomenon is observed in this case?

Codominance

Semidominance

Polymery

Pleiotropy

Complementary interaction

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A patient with Itsenko-Cushing syndrome has persistent hyperglycemia and glycosuria, hypertension, osteoporosis, obesity. Increased synthesis and hypersecretion of the following hormone will be observed in this case:

Thyroxin

Cortisol

Glucagon

Aldosterone

Adrenaline

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A patient was delivered to the admission ward with poisoning with an insecticide of anticholinesterase action. What drug able to block muscarinic choli-noreceptors should be prescribed?

Dithylinum

Pilocarpine hydrochloride

Benzohexonium

Mesatonum

Atropine sulfate

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A 15 year old girl was delivered to the hospital with inflammation of vermiform appendix. Blood analysis revealed signs of anaemia. Her feces contained lemon-shaped helminthic eggs (50x30 micrometer) with 'plugs' on the poles. What type of helminth is it?

Hookworm

Echinococcus

Trichuris

Hymenolepis nana

Pinworm

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Prophylactic medical examination of a 7 year old boy revealed that the boy had Lesch-Nyhan syndrome (only boys can be affected). His parents are healthy but his grandfather by his mother’s side has the same diagnosis. What is the type of disease inheritance?

Recessive, sex-linked

Autosomally recessive

Dominant, sex-linked

Semidominance

Autosomally dominant

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Endoscopic examination of duodenum revealed a tumour of the major papilla. This pathological formation is localized in the following part of duodenum:

Ascending part

Superior part

Horizontal part

Descending part

Superior flexure

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Autopsy revealed that the upper lobe of the right lung was enlarged, grey, airless; surface of incision was dripping with turbid liquid; pleura had a lot of fibrinous plicae. Microscopical examination of alveoles revealed exudate containing neutrophils, desquamated alveolocytes and fibrin fibres. Bronchus wall was intact. What is the most probable diagnosis?

Influenzal pneumonia

Focal pneumonia

Interstitial pneumonia

Croupous pneumonia

Pulmonary abscess

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Examination of mountain climbers who have spent a long time in a high-altitude region revealed increase of erythrocyte number (over 6 • 1012/l) and haemoglobin concentration ( over 170 g/l). What mechanism caused this phenomenon?

Weakening of erythrocyte haemolysis in bloodstream

Improved ability of tissue for oxygen utilization

Weakening of intracellular erythrocyte haemolysis

Intensified production of erythropoietin by the kidneys

Intensified processes of anoxic energy production

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A 60 year old patient complains of tongue burning, excessive salivation and glossalgia effects that came 5 days after he started using a metal dental bridge. Objectively: mucous membrane of oral cavity is edematic and hyperemic. What form of stomatitis is it?

Fibrinous

Catarrhal

Purulent

Gangrenous

Ulcerous

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A patient underwent extraction of a tooth with oval crown and two tubercles on its masticatory surface. Its root is strongly flattened in mesiodistal direction, its apex is bifurcated. What tooth was extracted?

First superior premolar

First inferior premolar

Second superior premolar

Second inferior premolar

Canine

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Analysis of a dentist’s urine obtained at the end of his working day revealed protein concentration at the rate of 0,7 g/l. His morning urine hadn’t such changes. What is this phenomenon called?

Nonselective proteinuria

Organic proteinuria

Extrarenal proteinuria

Functional proteinuria

Hematuria

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As a result of a trauma a patient has got disfunction of lachrymal gland. What nerve is responsible for its secretion?

N. petrosus minor

N. occipitalis minor

N. auricularis magnus

N. petrosus major

Chorda tympany

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Pathological material taken from a patient suffering from pulpitis was inoculated onto KittTarozzi cultural medium. It is planned to find the following microorganisms:

Aerobic

Anaerobic

Acid-resistant

Haemolytic

Acidophilic

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The 16th tooth of a patient is missing. X-ray picture shows in the depth of alveolar process rarefaction of bone and a well-defined cavity that contained the underdeveloped tooth crown. Microscopical examination revealed that the cavity wall was lined with stratified squamous epithelium and enclosed within a fibrous capsule. Make a diagnosis:

Cyst of the incisive canal

Primordial gnathic cyst

Cystic ameloblastoma of jaw

Follicular gnathic cyst

Radicular gnathic cyst

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A 52 year old patient suffering from cancer of the lower jaw underwent a course of radiation therapy. The tumour has remitted. Which mechanism of cell destruction ensures efficiency of radiation therapy most of all?

Lysis by natural killer cells

Mutagenesis

Generation of free radicals

Vessel thrombosis

Hyperthermia

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A histological specimen presents a developed tooth that has a coating resistant to acids, but it can be found only on the lateral surfaces of the tooth. What coating is meant?

Enamel pellicle

Cuticle

Dentine

Cement

Enamel

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A sensory nerve ganglion consists of roundish neurocytes with one process that divides into axon and dendrite at a certain distance from perikaryon. What are such cells called?

Apolar

Bipolar

Pseudounipolar

Multipolar

Unipolar

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Roentgenological examination of a patient revealed a cyst enclosing a tooth in its cavity in the area of the premolar. Microscopical examination revealed that the cyst wall consisted of connective tissue and was lined with multilayer squamous epithelium. What is the most probable diagnosis?

Radicular cyst

Follicular cyst

Epulis

Eosinophilic granuloma

Primordial cyst

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A patient consulted a dentist about itching and burning in the oral cavity; high temperature. The patient was diagnosed with trichomonal gingivostomatitis. What drug should be chosen for his treatment?

Gentamicin sulfate

Ampicillin

Doxycycline hydrochloride

Metronidazole

Nystatin

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A patient with a tumour in the area of superior tubercles of quadrigeminal plate has lost pupillary reflex. This is most probably caused by dysfunction of the following nucleus of cranial nerves:

Accessory nucleus of oculomotor nerve

Motor nucleus of oculomotor nerve

Motor nucleus of abducent nerve

Motor nucleus of trochlear nerve

Motor nucleus of accessory nerve

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What preventive medications should be injected to a patient with open maxillofacial trauma provided that he has never got prophylactic vaccination before?

Diphtheria, tetanus toxoids and pertussis vaccine and antibiotics

Antitetanus immunoglobulin and anatoxin

Anticonvulsive drugs and anatoxin

Tetanus anatoxin and antibiotics

Antitetanus serum and antibiotics

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Microscopic examination of periodontium revealed plethoric vessels, edema of connective tissue along with infiltration by single neutrophils. What type of exudative inflammation in the periodontium is it?

Putrid

Serous

Fibrinous

Catarrhal

Purulent

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Histological study of an extirpated pulp revealed some cylindrical cells in its peripheral layer. What are these cells called?

Monocytes

Ameloblasts

Fibroblasts

Myofibroblasts

Odontoblasts

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During examination of a patient a dentist revealed carious cavities on the front teeth that don’t have accessory antagonists. What teeth are meant?

Superior canines

Inferior medial incisors

Superior medial incisors

Inferior lateral incisors

Superior lateral incisors

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